Abstract：
:Acute kidney disease (AKD), or renal dysfunction persisting >7 days after an initiating event of acute kidney injury, is a rising concern. This study aimed to elucidate the clinical course of AKD after cardiac surgery with data on post-cardiac surgery patients admitted to intensive care units (ICU) at 18 Japanese hospitals during 2012-2014. Using multivariable logistic models, we evaluated the association of AKD with 90-day mortality and the 50% eGFR decline during 2-year follow-up compared to eGFR at 90 days. AKD was defined as an elevation in serum creatinine to at least 1.5-fold from baseline in >7 days after ICU admission. Of the 3,605 eligible patients undergoing cardiac surgery, 403 patients (11.2%) had AKD. Multivariable analysis revealed that the adjusted odds ratio (OR) of AKD for 90-day mortality was 63.0 (95% confidence interval [CI], 27.9-180.6). In addition, the adjusted OR of AKD for 50% eGFR decline was 3.56 (95% CI, 2.24-5.57) among hospital survivors. In conclusion, AKD after cardiac surgery was associated with higher 90-day mortality and renal function decline after hospital discharge.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Matsuura R,Iwagami M,Moriya H,Ohtake T,Hamasaki Y,Nangaku M,Doi K,Kobayashi S,Noiri Edoi
10.1038/s41598-020-62981-1subject
Has Abstractpub_date
2020-04-16 00:00:00pages
6490issue
1issn
2045-2322pii
10.1038/s41598-020-62981-1journal_volume
10pub_type
杂志文章abstract：:Birds play unique functional roles in the maintenance of ecosystems, such as pollination and seed dispersal, and thus monitoring bird species diversity is a first step towards avoiding undesirable consequences of anthropogenic impacts on bird communities. In the present study, we hypothesized that birds, regardless of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22817-5
更新日期：2018-03-14 00:00:00
abstract：:In this paper, we propose an angle- and polarization-insensitive metamaterial absorber. We design a metamaterial unit cell that is based on a split ring cross resonator (SRCR). We observe that the absorption frequency and absorption ratio are insensitive to incident angles when a via array surrounds the SRR. We demons...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39686
更新日期：2016-12-21 00:00:00
abstract：:Global exponential increase in levels of Photovoltaic (PV) module waste is an increasing concern. The purpose of this study is to investigate if there is energy value in the polymers contained within first-generation crystalline silicon (c-Si) PV modules to help contribute positively to recycling rates and the circula...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41762-5
更新日期：2019-03-27 00:00:00
abstract：:Huntington's disease (HD) is a progressive and fatal neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene. Although HD is monogenic, its molecular manifestation appears highly complex and involves multiple cellular processes. The recent application of high throughput platforms such as mic...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05224-0
更新日期：2017-07-12 00:00:00
abstract：:Abscisic acid (ABA) is an ancient stress hormone and is detectable in a wide variety of organisms where it regulates innate immunity and inflammation. Previously, we showed that oral supplementation with ABA decreased parasitemia in a mouse model of malaria, decreased liver and spleen pathology and reduced parasite tr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-27073-1
更新日期：2018-06-11 00:00:00
abstract：:Mulching with organic materials is a management practice with long history for weed suppression, soil water conservation and erosion control. Its potential impact on crop pests is less well explored. Here we report its utility for reducing crop damage by the serious pest, sweetpotato weevil (Cylas formicarius). Labora...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50521-5
更新日期：2019-10-16 00:00:00
abstract：:Currently, diagnostic testing for Lyme disease is done by determination of the serologic responses to Borrelia burgdorferi antigens, with the exception of the early localized phase of disease where diagnosis must be done clinically. Here, we describe the use of microfluidics technology to develop a multiplexed rapid l...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35069
更新日期：2016-10-11 00:00:00
abstract：ABSTARCT:Graphene has sparked extensive research interest for its excellent physical properties and its unique potential for application in absorption of electromagnetic waves. However, the processing of stable large-scale graphene and magnetic particles on a micrometer-thick conductive support is a formidable challeng...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-02639-7
更新日期：2017-05-24 00:00:00
abstract：:In general, the poultry industry uses 0.5-1 ppm chlorine solution in the meat sanitization process. However, chlorine can react with organic material and produce halogenated organic compounds, notably chloroform, which causes bladder and rectal cancer in humans. For this reason, many industries try to avoid chlorine. ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-58199-w
更新日期：2020-01-31 00:00:00
abstract：:Amyloid plaques composed of Aβ amyloid peptides and neurofibrillary tangles are a pathological hallmark of Alzheimer's disease. In situ identification of early-stage amyloid aggregates in Alzheimer's disease is relevant for their importance as potential targets for effective drugs. Synchrotron-based infrared imaging i...
journal_title：Scientific reports
pub_type： 杂志文章,收录出版
doi：10.1038/s41598-020-62708-2
更新日期：2020-04-03 00:00:00
abstract：:Photodynamic therapy (PDT) is an efficacious treatment for some types of cancers. However, PDT-induced tumor hypoxia as a result of oxygen consumption and vascular damage can reduce the efficacy of this therapy. Measuring and monitoring intrinsic and PDT-induced tumor hypoxia in vivo during PDT is of high interest for...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep31551
更新日期：2016-08-22 00:00:00
abstract：:Galectin-3 is a biomarker of fibrosis, inflammation and oxidative stress, and its role in heart remodelling and exercise intolerance has not been conclusively proven in heart failure (HF) patients with reduced ejection fraction (rEF). We prospectively assessed 67 consecutive patients with symptomatic HF and left ventr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73634-8
更新日期：2020-10-07 00:00:00
abstract：:Converging evidence from laboratory models pointed that the widely used antidiabetic drug metformin has direct effects on cancer cells. Thus far, relatively little attention has been addressed to the drug exposures used experimentally relative to those achievable clinically. Here, we demonstrated that metformin loaded...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-01118-3
更新日期：2017-04-21 00:00:00
abstract：:A metal-free three component cyclization reaction with amidation is devised for direct synthesis of DFT-designed amido-phenazine derivative bearing noncovalent gluing interactions to fabricate organic nanomaterials. Composition-dependent organic nanoelectronics for nonvolatile memory devices are discovered using mixed...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13754-w
更新日期：2017-10-17 00:00:00
abstract：:ABX464 is a first-in-class, clinical-stage, small molecule for oral administration that has shown strong anti-inflammatory effects in the DSS-model for inflammatory bowel disease (IBD) and also prevents replication of the HIV virus. ABX464 which binds to cap binding complex (CBC) has demonstrated safety and efficacy i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37813-y
更新日期：2019-01-28 00:00:00
abstract：:Various treatment methods for tracheal defects have been attempted, such as artificial implants, allografts, autogenous grafts, and tissue engineering; however, no perfect method has been established. We attempted to create an effective artificial trachea via a tissue engineering method using 3D bio-printing. A multi-...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-38565-z
更新日期：2019-02-14 00:00:00
abstract：:Transit-time flow measurement (TTFM) is frequently used to evaluate intraoperative quality control during coronary artery bypass grafting (CABG) and has the ability to assess graft failure intraoperatively. However, perioperative factors affecting TTFM during CABG remain poorly understood. Patients who underwent CABG ...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/s41598-020-69924-w
更新日期：2020-07-31 00:00:00
abstract：:Synapse and dendritic spine loss induced by amyloid-β oligomers is one of the main hallmarks of the early phases of Alzheimer's disease (AD) and is directly correlated with the cognitive decline typical of this pathology. The p75 neurotrophin receptor (p75NTR) binds amyloid-β oligomers in the nM range. While it was sh...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-70153-4
更新日期：2020-08-07 00:00:00
abstract：:Irisin is conventionally regarded as a myokine involved in the browning of white adipose tissue, energy expenditure and glucose tolerance. Its potential link to fat accumulation and metabolic dysfunction is debated. We sought to explore the relationship between circulating irisin and components of body composition in ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-57855-5
更新日期：2020-01-23 00:00:00
abstract：:Fish reproductive success is linked to the ability of couples to mate and produce clutches that successfully hatch. Environmental stressors like high temperature and low pH can jeopardize this energetically costly process. In this study, exposure to high temperature and low pH was tested on a marine temperate species,...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-77906-1
更新日期：2020-11-30 00:00:00
abstract：:The effect of different contact configurations (semi-infinite extended-channel, normal metal and ferromagnetic metal) on quantum transport through thin Bi2Se3 three-dimensional (3D) topological insulator (TI) slab (channel) has been investigated through Non-Equilibrium Green Function. The issue of contact dependent cu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09479
更新日期：2015-03-30 00:00:00
abstract：:A highly sensitive bismuth/silver nanoparticles/Nafion-modified screen-printed graphene electrode was fabricated and was utilized for the detection of trace lead (Pb) concentrations in river water samples prior to and after remediation using calamansi (Citrofortunella Microcarpa) rinds in different forms viz., ground ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80672-9
更新日期：2021-01-14 00:00:00
abstract：:Cardiac progenitor cells (CPCs) have been shown to promote cardiac regeneration and improve heart function. However, evidence suggests that their regenerative capacity may be limited in conditions of severe hypoxia. Elucidating the mechanisms involved in CPC protection against hypoxic stress is essential to maximize t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09813-x
更新日期：2017-08-29 00:00:00
abstract：:Protective antigen (PA) of Bacillus anthracis is being considered as a vaccine candidate against anthrax and its production has been explored in several heterologous host systems. Since the systems tested introduced adverse issues such as inclusion body formation and endotoxin contamination, the production from B. ant...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34196-y
更新日期：2018-10-31 00:00:00
abstract：:The effects of antithrombotic drugs on random and free flap survival have been investigated in the past, but the experimental and clinical results are not in agreement. A perforator-based critical ischaemia model was used to evaluate the effects of different perioperatively administered pharmaceutical agents on tissue...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35833
更新日期：2016-10-21 00:00:00
abstract：:We tried to establish a reliable detrusor underactivity (DUA) rat model and to investigate pathophysiology of chronic bladder ischemia (CBI) on voiding behavior and bladder function. Adult male rats were divided into five groups. The arterial injury (AI) groups (AI-10, AI-20, AI-30) underwent vascular endothelial dama...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52811-4
更新日期：2019-11-08 00:00:00
abstract：:In arid and semiarid regions, low precipitation rates lead to soil salinity problems, which may limit plant establishment, growth, and survival. Herein, we investigated the NaCl stress effect on chlorophyll fluorescence, photosynthetic-pigments, movement and chloroplasts ultrastructure in chlorenchyma cells of Opuntia...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08744-x
更新日期：2017-08-17 00:00:00
abstract：:Overexpression of hST3Gal1 leads to hypersialylation of cell-surface glycoconjugates, a cancer-associated condition that promotes cell growth, migration and invasion. Upregulation of this enzyme in ovarian cancer is linked to cancer progression and metastasis, contributing also to chemotherapy resistance. Strategies f...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-54384-8
更新日期：2019-11-29 00:00:00
abstract：:Molecular behaviour of liquid water under proton irradiation is of great importance to a number of technological and medical applications. The highly energetic proton generates a time-varying field that is highly localized and heterogeneous at the molecular scale, and massive electronic excitations are produced as a r...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40379
更新日期：2017-01-13 00:00:00
abstract：:Tsetse flies are the transmitting vector of trypanosomes causing human sleeping sickness and animal trypanosomiasis in sub-saharan Africa. 3-alkylphenols are used as attractants in tsetse fly traps to reduce the spread of the disease. Here we present an inexpensive production method for 3-ethylphenol (3-EP) and 3-prop...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66997-5
更新日期：2020-06-19 00:00:00
