Abstract:
:This study examined global resting-state functional connectivity of neural oscillations in individuals with chronic tinnitus and normal and impaired hearing. We tested the hypothesis that distinct neural oscillatory networks are engaged in tinnitus with and without hearing loss. In both tinnitus groups, with and without hearing loss, we identified multiple frequency band-dependent regions of increased and decreased global functional connectivity. We also found that the auditory domain of tinnitus severity, assayed by the Tinnitus Functional Index, was associated with global functional connectivity in both auditory and nonauditory regions. These findings provide candidate biomarkers to target and monitor treatments for tinnitus with and without hearing loss.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Demopoulos C,Duong X,Hinkley LB,Ranasinghe KG,Mizuiri D,Garrett C,Honma S,Henderson-Sabes J,Findlay A,Racine-Belkoura C,Cheung SW,Nagarajan SSdoi
10.1002/hbm.24981subject
Has Abstractpub_date
2020-07-01 00:00:00pages
2846-2861issue
10eissn
1065-9471issn
1097-0193journal_volume
41pub_type
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