Global resting-state functional connectivity of neural oscillations in tinnitus with and without hearing loss.

Abstract:

:This study examined global resting-state functional connectivity of neural oscillations in individuals with chronic tinnitus and normal and impaired hearing. We tested the hypothesis that distinct neural oscillatory networks are engaged in tinnitus with and without hearing loss. In both tinnitus groups, with and without hearing loss, we identified multiple frequency band-dependent regions of increased and decreased global functional connectivity. We also found that the auditory domain of tinnitus severity, assayed by the Tinnitus Functional Index, was associated with global functional connectivity in both auditory and nonauditory regions. These findings provide candidate biomarkers to target and monitor treatments for tinnitus with and without hearing loss.

journal_name

Hum Brain Mapp

journal_title

Human brain mapping

authors

Demopoulos C,Duong X,Hinkley LB,Ranasinghe KG,Mizuiri D,Garrett C,Honma S,Henderson-Sabes J,Findlay A,Racine-Belkoura C,Cheung SW,Nagarajan SS

doi

10.1002/hbm.24981

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

2846-2861

issue

10

eissn

1065-9471

issn

1097-0193

journal_volume

41

pub_type

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