Cardiac Computed Tomography Perfusion: Contrast Agents, Challenges and Emerging Methodologies from Preclinical Research to the Clinics.

Abstract:

:Computed Tomography (CT) has long been regarded as a purely anatomical imaging modality. Recent advances on CT technology and Contrast Agents (CA) in both clinical and preclinical cardiac imaging offer opportunities for the use of CT in functional imaging. Combined with modern ECG-gating techniques, functional CT has now become a reality allowing a comprehensive evaluation of myocardial global and regional function, perfusion and coronary angiography. This article aims at reviewing the current status of cardiac CT perfusion and micro-CT perfusion with established and experimental scanners and contrast agents, from clinical practice to the experimental domain of investigations based on animal models of heart diseases.

journal_name

Acad Radiol

journal_title

Academic radiology

authors

Panetta D,Gabelloni M,Faggioni L,Pelosi G,Aringhieri G,Caramella D,Salvadori PA

doi

10.1016/j.acra.2019.12.026

subject

Has Abstract

pub_date

2021-01-01 00:00:00

pages

e1-e13

issue

1

eissn

1076-6332

issn

1878-4046

pii

S1076-6332(20)30023-4

journal_volume

28

pub_type

杂志文章,评审
  • Results of the 1993 survey of the American Association of Academic Chief Residents in Radiology.

    abstract:RATIONALE AND OBJECTIVES:A survey of chief residents of academic radiology programs is conducted annually on behalf of the American Association of Academic Chief Residents in Radiology (A3CR2). Data are obtained to improve the training of diagnostic radiology residents and to increase the understanding of radiologists ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(05)80835-9

    authors: Oser AB,Baker SM,Wilson AJ,Evens RG

    更新日期:1994-10-01 00:00:00

  • Does biopsy, aspiration or six-month follow-up of a false-positive mammogram reduce future screening or have large psychosocial effects?

    abstract:RATIONALE AND OBJECTIVES:To determine the differences in the psychosocial effects and future mammography screening behavior between women who had an abnormal mammogram followed either by percutaneous or open surgical breast biopsy or cyst aspiration, or by short-term follow-up mammography to provide insight to radiolog...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(03)00382-9

    authors: Currence BV,Pisano ED,Earp JA,Moore A,Chiu YF,Brown ME,Kurgat KL

    更新日期:2003-11-01 00:00:00

  • Imaging Volume Trends and Recovery During the COVID-19 Pandemic: A Comparative Analysis Between a Large Urban Academic Hospital and Its Affiliated Imaging Centers.

    abstract:RATIONALE AND OBJECTIVES:While affiliated imaging centers play an important role in healthcare systems, little is known of how their operations are impacted by the COVID-19 pandemic. Our goal was to investigate imaging volume trends during the pandemic at our large academic hospital compared to the affiliated imaging c...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2020.08.008

    authors: Lang M,Yeung T,Mendoza DP,Flores EJ,Som A,Lang AL,Pianykh OS,Lee SI,Saini S,Little BP,Succi MD

    更新日期:2020-10-01 00:00:00

  • Cause of satisfaction of search effects in contrast studies of the abdomen.

    abstract:RATIONALE AND OBJECTIVES:Extraintestinal abnormalities visible without contrast material on abdominal radiographs are reported less frequently when contrast examinations are performed. Gaze dwell time was used to determine whether this difference is due to failure by observers to scan plain-film regions of contrast stu...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(96)80271-6

    authors: Berbaum KS,Franken EA Jr,Dorfman DD,Miller EM,Krupinski EA,Kreinbring K,Caldwell RT,Lu CH

    更新日期:1996-10-01 00:00:00

  • Automatic determination of differential coronary artery motion minima for cardiac computed tomography optimal phase selection.

    abstract:RATIONALE AND OBJECTIVES:Selecting the optimal phase for coronary artery evaluation can be challenging, especially at higher heart rates, given that the optimal phase may differ for each of the coronary arteries. This study aimed to evaluate a novel vessel-specific algorithm which automatically outputs the minimum moti...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2015.01.013

    authors: Lessick J,Klass O,Wuchenauer S,Walker MJ,Schmitt H,Peters J,Weese J,Brunner H,Vembar M,Grass M,Aronson D,Hoffmann MH

    更新日期:2015-06-01 00:00:00

  • System for robotically assisted prostate biopsy and therapy with intraoperative CT guidance.

    abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to assess the work-in-progress prototype of an image-guided, robotic system for accurate and consistent placement of transperineal needles into the prostate with intraoperative image guidance inside the gantry of a computed tomographic (CT) scanner. MATERIALS AND ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(03)80297-0

    authors: Fichtinger G,DeWeese TL,Patriciu A,Tanacs A,Mazilu D,Anderson JH,Masamune K,Taylor RH,Stoianovici D

    更新日期:2002-01-01 00:00:00

  • MRI-based delta-radiomics are predictive of pathological complete response after neoadjuvant chemoradiotherapy in locally advanced rectal cancer.

    abstract:RATIONALE AND OBJECTIVES:To investigate the capability of delta-radiomics to predict pathological complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) in patients with locally advanced rectal cancer (LARC). MATERIALS AND METHODS:This retrospective study enrolled 165 consecutive patients with LARC (traini...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2020.10.026

    authors: Wan L,Peng W,Zou S,Ye F,Geng Y,Ouyang H,Zhao X,Zhang H

    更新日期:2020-11-11 00:00:00

  • Optimal contrast agents for vascular imaging on computed tomography: iodixanol versus iohexol.

    abstract:RATIONALE AND OBJECTIVES:Dimeric nonionic iodinated contrast has a lower osmolality than monomeric nonionic iodinated contrast but is available at lower iodine concentrations. Less dilution of intravascular fluid by influx from the extravascular space is proposed to occur with decreasing osmolality. The purpose of this...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2005.01.015

    authors: Pannu HK,Thompson RE,Phelps J,Magee CA,Fishman EK

    更新日期:2005-05-01 00:00:00

  • Nephrogenic systemic fibrosis and management of high-risk patients.

    abstract::The purpose of this work is to provide current information on the rapidly evolving subject of nephrogenic systemic fibrosis (NSF), to establish the radiologic approach to the management of high-risk patients for NSF, and to assess the probabilistic risk of NSF compared to contrast induced nephropathy (CIN), as encount...

    journal_title:Academic radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.acra.2009.01.001

    authors: Altun E,Semelka RC,Cakit C

    更新日期:2009-07-01 00:00:00

  • Apprenticeships ease the transition to independent call: an evaluation of anxiety and confidence among junior radiology residents.

    abstract:RATIONALE AND OBJECTIVES:The aims of this study were to quantify resident anxiety when beginning independent call and to assess whether an apprenticeship experience (buddy call) can lessen anxiety and improve confidence. MATERIALS AND METHODS:A prospective cohort comparison of two groups of radiology residents beginni...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2011.04.015

    authors: Trout AT,Wang PI,Cohan RH,Bailey JE,Khalatbari S,Myles JD,Dunnick NR

    更新日期:2011-09-01 00:00:00

  • Role of endothelium-derived nitric oxide-endothelin balance in contrast medium-induced acute renal vasoconstriction in dogs.

    abstract:RATIONALE AND OBJECTIVES:The authors evaluated the involvement of nitric oxide and endothelin in radiographic contrast medium-induced changes in renal hemodynamics. METHODS:Eleven anesthetized healthy dogs were each studied during three periods. Thirty minutes before the first, second, and third periods, the dogs rece...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(97)80115-8

    authors: Bagnis C,Idee JM,Dubois M,Jacquiaud C,Maistre G,Jacobs C,Deray G

    更新日期:1997-05-01 00:00:00

  • Diffusion-weighted imaging of prostate cancer on 3T MR: Relationship between apparent diffusion coefficient values and Ki-67 expression.

    abstract:RATIONALE AND OBJECTIVES:To investigate the relationship between apparent diffusion coefficient (ADC) values and the Ki-67 staining index (Ki-67 SI), a tumor proliferation marker, in prostate cancer (PCa). MATERIALS AND METHODS:Forty-three patients with PCa and thirty-six patients with benign prostatic hyperplasia (BP...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2013.09.007

    authors: Zhang J,Jing H,Han X,Huang Z,Cao Z,Liu Q

    更新日期:2013-12-01 00:00:00

  • Performance of T2 Maps in the Detection of Prostate Cancer.

    abstract:RATIONALE AND OBJECTIVES:This study compares the performance of T2 maps in the detection of prostate cancer (PCa) in comparison to T2-weighted (T2W) magnetic resonance images. MATERIALS AND METHODS:The prospective study was institutional review board approved. Consenting patients (n = 45) with histologic confirmed PCa...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2018.04.005

    authors: Chatterjee A,Devaraj A,Mathew M,Szasz T,Antic T,Karczmar GS,Oto A

    更新日期:2019-01-01 00:00:00

  • Correlation Between Cardiac Computed Tomography and Histopathology for Evaluating Patients with Aortic Valve Disease.

    abstract:BACKGROUND:The use of cardiac computed tomography (cardiac CT) and the quantification of the Agatston score for the evaluation of calcium of the aortic valve (AVC) has increased in different clinical contexts for diagnostic and prognostic purposes. This study aims to evaluate the correlation between cardiac CT and hist...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2020.12.015

    authors: Saucedo-Orozco H,Torres IP,Vera SAC,Frausto AA,Godínez JAA,Guarner-Lans V,Rubio E,López MES

    更新日期:2021-01-14 00:00:00

  • Magnetic resonance lymphography in rats: effects of muscular activity and hyperthermia on the lymph node uptake of intravenously injected superparamagnetic iron oxide particles.

    abstract:RATIONALE AND OBJECTIVES:We investigated the influence of muscular activity and regional body temperature changes on the accumulation of intravenously (i.v.) administered, dextran-coated superparamagnetic iron oxide (SPIO) particles in the lymph nodes of rats. METHODS:Four groups of rats (N = 21) were used. Five rats ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(96)80193-0

    authors: Elste V,Wagner S,Taupitz M,Pfefferer D,Kresse M,Hamm B,Berg R,Wolf KJ,Semmler W

    更新日期:1996-08-01 00:00:00

  • A pulmonary nodule view system for the Lung Image Database Consortium (LIDC).

    abstract:RATIONALE AND OBJECTIVES:The aim of this study was to develop a pulmonary nodule viewing system to visualize and retrieve data from the Lung Image Database Consortium. MATERIALS AND METHODS:The pulmonary nodule viewing system, developed using Microsoft C++ and the .NET 2.0 Framework, is composed of a clinical informat...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2011.04.006

    authors: Lin H,Chen Z,Wang W

    更新日期:2011-09-01 00:00:00

  • Microvascular versus macrovascular cerebral vasomotor reactivity in patients with severe internal carotid artery stenosis or occlusion.

    abstract:RATIONALE AND OBJECTIVES:In patients with severe internal carotid artery steno-occlusive lesions (ISOL), impaired cerebrovascular reactivity (CVR) is predictive of future ischemic stroke (IS) or transient ischemic attack (TIA). Therefore, the evaluation of CVR in ISOL patients may be a means to evaluate the risk for IS...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2013.10.010

    authors: Zirak P,Delgado-Mederos R,Dinia L,Martí-Fàbregas J,Durduran T

    更新日期:2014-02-01 00:00:00

  • Intraarterial biocompatibility of polyethylene terephthalate self-expandable stents implanted in porcine peripheral arteries.

    abstract:RATIONALE AND OBJECTIVES:We tested deployment feasibility and intraarterial biocompatibility of polyethylene terephthalate (PET) self-expandable vascular stents in a porcine peripheral artery model. METHODS:To assess the thrombogenicity and neointimal response to oversized PET self-expandable stents, we implanted 10 s...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/S1076-6332(05)80151-5

    authors: De Scheerder IK,Wilczek KV,Verbeken EV,Barios L,Piessens J,De Geest H

    更新日期:1995-02-01 00:00:00

  • Providing Feedback: Practical Skills and Strategies.

    abstract::Feedback is an essential component of education. It is designed to influence, reinforce, and change behaviors, concepts, and attitudes in learners. Although providing constructive feedback can be challenging, it is a learnable skill. The negative consequences of destructive feedback or lack of feedback all together ar...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2016.11.023

    authors: Sarkany D,Deitte L

    更新日期:2017-06-01 00:00:00

  • CT-guided Drainage of Deep Pelvic Abscesses via a Percutaneous Presacral Space Approach: A Clinical Report and Review of the Literature.

    abstract:RATIONALE AND OBJECTIVES:Some deep pelvic abscesses are not accessible through anterior or lateral approaches because of the presence of organs and structures. The objective of this study was to assess the feasibility, safety, tolerability, and efficacy of a percutaneous presacral space approach by reviewing our clinic...

    journal_title:Academic radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.acra.2016.06.009

    authors: Peng T,Dong L,Zhu Z,Cui J,Li Q,Li X,Wu H,Wang C,Yang Z

    更新日期:2016-12-01 00:00:00

  • Evaluation of the quality of radiology requisitions for intensive care unit patients.

    abstract:RATIONALE AND OBJECTIVES:The study aim is to evaluate the quality of radiology requisitions for plain film radiographs on intensive care unit (ICU) patients. MATERIALS AND METHODS:Radiology requisitions for 58 patients in ICU units at our children's hospital and the corresponding original orders for the study, written...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2005.10.017

    authors: Cohen MD,Curtin S,Lee R

    更新日期:2006-02-01 00:00:00

  • Selection of subtle cases for observer-performance studies: the importance of knowing the true diagnosis.

    abstract:RATIONALE AND OBJECTIVES:To assess the usefulness of classifying degree of difficulty in abnormality detection and to determine the effect of knowing the true diagnosis when selecting subtle images for observer-performance studies. MATERIALS AND METHODS:A total of 529 posteroanterior chest images that had been used in...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(98)80127-x

    authors: Rockette HE,King JL,Thaete FL,Fuhrman CR,Slifko RM,Gur D

    更新日期:1998-02-01 00:00:00

  • Optimization of TI values in inversion-recovery MR sequences for the depiction of fine structures within gray and white matter: separation of globus pallidus interna and externa.

    abstract:RATIONALE AND OBJECTIVES:The authors' purpose was to search the inversion time (TI) values that enable the best differentiation of fine structures in gray matter (gray-gray differentiation). MATERIALS AND METHODS:Seven healthy adult volunteers with no history of neurologic disease or head trauma were recruited and gav...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(03)80789-4

    authors: Nakamura H,Yamada K,Kizu O,Ito H,Nishimura T

    更新日期:2003-01-01 00:00:00

  • A Breast Radiology Department-operated, Proactive Same-day Program Identifies Pathogenic Breast Cancer Mutations in Unaffected Women.

    abstract:RATIONALE AND OBJECTIVES:Pathogenic mutations in some genes elevate women's breast cancer risk, necessitating risk-reduction strategies. Unfortunately, women are underscreened for cancer risk, and when identified as potentially high risk, women seldom pursue genetic counseling or testing. To improve cancer risk managem...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2020.12.005

    authors: Loving VA,Luiten RC,Siettmann JM,Mina LA

    更新日期:2020-12-15 00:00:00

  • A permutation test for comparing ROC curves in multireader studies a multi-reader ROC, permutation test.

    abstract:RATIONALE AND OBJECTIVES:The aim of the study is to develop a permutation test to compare receiver operating characteristic (ROC) curves of two diagnostic modalities in a multireader paired design. MATERIALS AND METHODS:A statistical test for comparing two diagnostic modalities is developed based on all possible excha...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2005.12.012

    authors: Bandos AI,Rockette HE,Gur D

    更新日期:2006-04-01 00:00:00

  • Lower limb vascular disease in diabetic patients: a study with calf compression contrast-enhanced magnetic resonance angiography at 3.0 Tesla.

    abstract:RATIONALE AND OBJECTIVES:To retrospectively analyze the significance of 3.0-T contrast-enhanced (CE) magnetic resonance angiography (MRA) with calf compression in the lower limbs of diabetic patients with peripheral vascular disease. MATERIALS AND METHODS:Sixty-one type 2 diabetes patients underwent both MRA and digit...

    journal_title:Academic radiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.acra.2011.01.013

    authors: Li J,Zhao JG,Li MH

    更新日期:2011-06-01 00:00:00

  • Deep Learning in the Prediction of Ischaemic Stroke Thrombolysis Functional Outcomes: A Pilot Study.

    abstract:RATIONALE AND OBJECTIVES:Intravenous thrombolysis decision-making and obtaining of consent would be assisted by an individualized risk-benefit ratio. Deep learning (DL) models may be able to assist with this patient selection. MATERIALS AND METHODS:Clinical data regarding consecutive patients who received intravenous ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2019.03.015

    authors: Bacchi S,Zerner T,Oakden-Rayner L,Kleinig T,Patel S,Jannes J

    更新日期:2020-02-01 00:00:00

  • The role of ultrasonography in the evaluation of abdominal fat: analysis of technical and methodological issues.

    abstract:RATIONALE AND OBJECTIVES:Ultrasonography (US) is becoming popular for the assessment of adiposity, but no one has studied this tool in the light of its potential limitations. Our purpose was to investigate the impact of technical conditions on the evaluation of abdominal fat by US. MATERIALS AND METHODS:Forty-five hea...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2013.07.009

    authors: Bazzocchi A,Filonzi G,Ponti F,Amadori M,Sassi C,Salizzoni E,Albisinni U,Battista G

    更新日期:2013-10-01 00:00:00

  • Relating dose of contrast media administered to uptake and washout of malignant lesions on DCEMRI of the breast.

    abstract:RATIONALE AND OBJECTIVES:To quantify the relationship between dose of contrast administered and contrast kinetics of malignant breast lesions. MATERIALS AND METHODS:A total of 108 patients with 120 malignant lesions were selected for an institutional review board-approved review. Dynamic magnetic resonance protocol: o...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2009.06.015

    authors: Jansen SA,Fan X,Yang C,Shimauchi A,Karczmar G,Newstead GM

    更新日期:2010-01-01 00:00:00

  • Bayesian regression methodology for estimating a receiver operating characteristic curve with two radiologic applications: prostate biopsy and spiral CT of ureteral stones.

    abstract:RATIONALE AND OBJECTIVES:The authors evaluated two Bayesian regression models for receiver operating characteristic (ROC) curve analysis of continuous diagnostic outcome data with covariates. MATERIALS AND METHODS:Full and partial Bayesian regression models were applied to data from two studies (n = 180 and 100, respe...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(03)80578-0

    authors: Omalley AJ,Zou KH,Fielding JR,Tempany CM

    更新日期:2001-08-01 00:00:00