Association between dental caries and adverse pregnancy outcomes.

abstract：:Cell counts decrease with sediment depth. Typical explanations consider limiting factors such as water availability and chemistry, carbon source, nutrients, energy and temperature, and overlook the role of pore size. Our analyses consider sediment self-compaction, the evolution of pore size with depth, and the probabi...

journal_title：Scientific reports

authors： Park J,Santamarina JC

更新日期：2020-12-10 00:00:00

abstract：:Ctenodactylinae (gundis) is a clade of rodents that experienced, in Miocene time, their greatest diversification and widest distribution. They expanded from the Far East, their area of origin, to Africa, which they entered from what would become the Arabian Peninsula. Questions concerning the origin of African Ctenoda...

journal_title：Scientific reports

authors： López-Antoñanzas R,Knoll F,Maksoud S,Azar D

更新日期：2015-08-07 00:00:00

abstract：:Alpha defensins are anti-microbial peptides of the innate immune system. The defensin A1 and A3 genes are located in a repeat array of variable copy number (the DEFA1A3 locus) and encode the human neutrophil peptides 1, 2 and 3. The possibility that copy number variation (CNV) may be associated with infection suscepti...

journal_title：Scientific reports

authors： Hughes T,Hansson L,Akkouh I,Hajdarevic R,Bringsli JS,Torsvik A,Inderhaug E,Steen VM,Djurovic S

更新日期：2020-06-04 00:00:00

abstract：:The tumor microenvironment (TME) plays critical roles in tumor growth and progression, however key regulators of gene expression in the TME of cutaneous malignant peripheral nerve sheath tumor (C-MPNST) and spindle cell melanoma (SCM) have not been well elucidated. Herein, we investigate the epigenetic regulation of p...

journal_title：Scientific reports

authors： Vougiouklakis T,Aung PP,Vasudevaraja V,Prieto VG,Torres-Cabala CA,Sulman EP,Snuderl M,Jour G

更新日期：2020-08-03 00:00:00

abstract：:Fundamental cell signaling mechanisms that regulate dynamic remodeling of the extracellular matrix (ECM) in mechanically loaded tissues are not yet clearly understood. Trabecular meshwork (TM) tissue in the eye is under constant mechanical stress and continuous remodeling of ECM is crucial to maintain normal aqueous h...

journal_title：Scientific reports

authors： Tellios N,Belrose JC,Tokarewicz AC,Hutnik C,Liu H,Leask A,Motolko M,Iijima M,Parapuram SK

更新日期：2017-04-11 00:00:00

abstract：:It has previously been shown that the consumption of probiotics may have beneficial effects not only on peripheral tissues but also on the central nervous system and behavior via the microbiota-gut-brain axis, raising the possibility that treatment with probiotics could be an effective therapeutic strategy for managin...

journal_title：Scientific reports

authors： Kobayashi Y,Sugahara H,Shimada K,Mitsuyama E,Kuhara T,Yasuoka A,Kondo T,Abe K,Xiao JZ

更新日期：2017-10-18 00:00:00

abstract：:Large sediment fluxes from mountain belts have the potential to cause megafans to prograde into the neighbouring sedimentary basins. These mechanisms have been documented based from numerical modelling and stratigraphic records. However, little attention has been focused on inferring temporal changes in the concentrat...

journal_title：Scientific reports

authors： Garefalakis P,Schlunegger F

更新日期：2018-01-09 00:00:00

abstract：:The formation of OD (order-disorder) phases of the LPSO (long-period stacking ordered)-type in Mg-Al-RE (RE (rare earth) = Y, La, Ce, Nd, Sm, Dy, Ho, Er and Yb) ternary systems has been investigated for both as-solidified and annealed conditions. The OD phase is found to form in those systems with RE = Y, Nd, Sm, Dy, ...

journal_title：Scientific reports

authors： Kishida K,Yokobayashi H,Inui H

更新日期：2017-09-25 00:00:00

abstract：:Both targeted therapy and immunotherapy have been used successfully to treat melanoma, but the development of resistance and poor response rates to the individual therapies has limited their success. Designing rational combinations of targeted therapy and immunotherapy may overcome these obstacles, but requires assess...

journal_title：Scientific reports

authors： Lelliott EJ,Cullinane C,Martin CA,Walker R,Ramsbottom KM,Souza-Fonseca-Guimaraes F,Abuhammad S,Michie J,Kirby L,Young RJ,Slater A,Lau P,Meeth K,Oliaro J,Haynes N,McArthur GA,Sheppard KE

更新日期：2019-02-04 00:00:00

abstract：:Listeria monocytogenes is an intracellular pathogen that causes listeriosis. Due to its intracellular niche, L. monocytogenes has evolved to limit immune recognition and response to infection. Antibodies that are slightly induced by listerial infection are completely unable to protect re-infection of L. monocytogenes....

journal_title：Scientific reports

authors： Asano K,Sashinami H,Osanai A,Hirose S,Ono HK,Narita K,Hu DL,Nakane A

更新日期：2016-12-22 00:00:00

abstract：:Protein kinase C-δ (PKC-δ), a member of the lipid-regulated serine/threonine PKC family, has been implicated in a wide range of important cellular processes, such as cell growth, differentiation, and apoptosis. Lampreys belong to the most primitive class of vertebrates, and there is little information on PKC-δ in thes...

journal_title：Scientific reports

authors： Xu Y,Zhu S,Zhao H,Li Q

更新日期：2017-09-22 00:00:00

abstract：:We present a detailed experimental and theoretical study of the acoustic phonon modes in rolled-up multilayers with thickness of the layers in the nanometre and diameters in the micrometre range. We compare our results to planar, unrolled multilayers grown by molecular beam epitaxy. For the planar multilayers the expe...

journal_title：Scientific reports

authors： Brick D,Engemaier V,Guo Y,Grossmann M,Li G,Grimm D,Schmidt OG,Schubert M,Gusev VE,Hettich M,Dekorsy T

更新日期：2017-07-14 00:00:00

abstract：:Selective inhibition of function-specific β-GlcNAcase has great potential in terms of drug design and biological research. The symmetrical bis-naphthalimide M-31850 was previously obtained by screening for specificity against human glycoconjugate-lytic β-GlcNAcase. Using protein-ligand co-crystallization and molecular...

journal_title：Scientific reports

authors： Liu T,Guo P,Zhou Y,Wang J,Chen L,Yang H,Qian X,Yang Q

更新日期：2014-08-26 00:00:00

abstract：:Silicon nanocrystals offer huge advantages compared to other semi-conductor quantum dots as they are made from an abundant, non-toxic material and are compatible with silicon devices. Besides, among a wealth of extraordinary properties ranging from catalysis to nanomedicine, metal nanoparticles are known to increase t...

journal_title：Scientific reports

authors： Goffard J,Gérard D,Miska P,Baudrion AL,Deturche R,Plain J

更新日期：2013-01-01 00:00:00

abstract：:Broadband acoustic absorbers with thin thickness are highly desired in practical situations such as architectural acoustics, yet it is still challenging to achieve high absorption by using structure with limited thickness. Here we report the theoretical optimal design, numerical simulation and experimental demonstrati...

journal_title：Scientific reports

authors： Gao YX,Lin YP,Zhu YF,Liang B,Yang J,Yang J,Cheng JC

更新日期：2020-07-01 00:00:00

abstract：:The most obvious method to observe transplanted islets in the liver is direct biopsy, but the distribution and location of the best biopsy site in the recipient's liver are poorly understood. Islets transplanted into the whole liver of five diabetic cynomolgus monkeys that underwent insulin-independent survival for an...

journal_title：Scientific reports

authors： Kim GS,Lee JH,Shin DY,Lee HS,Park H,Lee KW,Yang HM,Kim SJ,Park JB

更新日期：2020-01-21 00:00:00

abstract：:Extracellular vesicles (EVs) have important roles in physiology, pathology, and more recently have been identified as efficient carriers of therapeutic cargoes. For efficient study of EVs, a single-step, rapid and scalable isolation strategy is necessary. Chromatography techniques are widely used for isolation of biol...

journal_title：Scientific reports

authors： Heath N,Grant L,De Oliveira TM,Rowlinson R,Osteikoetxea X,Dekker N,Overman R

更新日期：2018-04-10 00:00:00

abstract：:Chromosome segment substitution lines (CSSLs) are useful tools for precise mapping of quantitative trait loci (QTLs) and the evaluation of gene action and interaction in inter-specific crosses. In this study, a set of 90 back cross lines at BC2F8 generation derived from Swarna x Oryza nivara IRGC81832 was evaluated fo...

journal_title：Scientific reports

authors： Balakrishnan D,Surapaneni M,Yadavalli VR,Addanki KR,Mesapogu S,Beerelli K,Neelamraju S

更新日期：2020-05-08 00:00:00

abstract：:Inflammatory and cardiovascular biomarkers have been associated with obesity, but little is known about how they change upon dietary intervention and concomitant weight loss. Further, protein biomarkers might be useful for predicting weight loss in overweight and obese individuals. We performed secondary analyses in t...

journal_title：Scientific reports

authors： Figarska SM,Rigdon J,Ganna A,Elmståhl S,Lind L,Gardner CD,Ingelsson E

更新日期：2020-05-13 00:00:00

abstract：:In March/April 2020 the Italian government drastically reduced vehicle traffic and interrupted all non-essential industrial activities over the entire national territory. Italy thus became the first country in the world, with the exception of Hubei, to enact lockdown measures as a consequence of the COVID-19 outbreak ...

journal_title：Scientific reports

authors： Poli P,Boaga J,Molinari I,Cascone V,Boschi L

更新日期：2020-06-10 00:00:00

abstract：:Solute segregating to grain boundary can stabilize the microstructure of nanocrystalline materials, but a lot of solutes also cause embrittlement effect on interfacial strength. Therefore, uncovering the solute effect on grain boundary strength is very important for nanocrystalline alloys design. In this work, we have...

journal_title：Scientific reports

authors： Huang Z,Wang P,Chen F,Shen Q,Zhang L

更新日期：2020-10-08 00:00:00

abstract：:Human behaviors exhibit ubiquitous correlations in many aspects, such as individual and collective levels, temporal and spatial dimensions, content, social and geographical layers. With rich Internet data of online behaviors becoming available, it attracts academic interests to explore human mobility similarity from t...

journal_title：Scientific reports

authors： Fan C,Liu Y,Huang J,Rong Z,Zhou T

更新日期：2017-09-20 00:00:00

abstract：:Wss1 is a DNA-protein crosslinks (DPCs) repair protein, which is responsible for degradation of the protein components in DPCs. In this investigation, crystal structure of the protease domain from saccharomyces cerevisiae Wss1 (ScWss1) was solved and was compared with the known crystal structure of Schizosaccharomyces...

journal_title：Scientific reports

authors： Yang X,Li Y,Gao Z,Li Z,Xu J,Wang W,Dong Y

更新日期：2017-08-15 00:00:00

abstract：:Gelatin-methacryloyl (GelMA) is one of the most commonly used photopolymerizable biomaterials in bio-applications. However, GelMA synthesis remains suboptimal, as its reaction parameters have not been fully investigated. The goal of this study is to establish an optimal route for effective and controllable GelMA synth...

journal_title：Scientific reports

authors： Shirahama H,Lee BH,Tan LP,Cho NJ

更新日期：2016-08-09 00:00:00

abstract：:Cisplatin is a highly effective anti-cancer chemotherapeutic agent; however, its clinical use is severely limited by serious side effects, of which nephrotoxicity is the most important. In this study, we investigated whether Qiong-Yu-Gao (QYG), a popular traditional Chinese medicinal formula described 840 years ago, e...

journal_title：Scientific reports

authors： Teng ZY,Cheng XL,Cai XT,Yang Y,Sun XY,Xu JD,Lu WG,Chen J,Hu CP,Zhou Q,Wang XN,Li SL,Cao P

更新日期：2015-10-29 00:00:00

abstract：:Virus production in the deep-sea environment has been found to be high, and viruses have been suggested to play significant roles in the overall functioning of this ecosystem. Nevertheless, little is known about these viruses, including the mechanisms that control their production, which makes them one of the least un...

journal_title：Scientific reports

authors： Jian H,Xiong L,Xu G,Xiao X,Wang F

更新日期：2016-02-22 00:00:00

abstract：:Malignant peripheral nerve sheath tumors (MPNST) are aggressive cancers that occur spontaneously (sporadic MPNST) or from benign plexiform neurofibromas in neurofibromatosis type 1 (NF1) patients. MPNSTs metastasize easily, are therapy resistant and are frequently fatal. The molecular changes underlying the malignant ...

journal_title：Scientific reports

authors： Amirnasr A,Verdijk RM,van Kuijk PF,Kartal P,Vriends ALM,French PJ,van Royen ME,Taal W,Sleijfer S,Wiemer EAC

更新日期：2020-02-19 00:00:00

abstract：:Atropa acuminata Royle Ex Lindl (Atropa acuminata) under tremendous threat of extinction in its natural habitat. However, the antimicrobial, antileishmanial and anticancer effects of the plant's extracts have not been reported yet. In the current study, an attempt has been made to evaluate the pharmacological potentia...

journal_title：Scientific reports

authors： Rahman K,Khan SU,Fahad S,Shinwari ZK,Khan D,Kamal S,Ullah I,Anjum SI,Man S,Khan AJ,Khan WU,Khan MHU,Jan M,Adnan M,Noor M

更新日期：2018-07-23 00:00:00

abstract：:This research utilized an external longitudinal dataset of hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) to compare and validate various predictive models that support the current recommendations to select the most effective predictive risk models to estimate short- and long-term mortality and fa...

journal_title：Scientific reports

authors： Shen Y,Wang X,Zhang S,Qin G,Liu Y,Lu Y,Liang F,Zhuang X

更新日期：2016-09-16 00:00:00

abstract：:In day-to-day life, humans usually perceive the location of sound sources as outside their heads. This externalized auditory spatial perception can be reproduced through headphones by recreating the sound pressure generated by the source at the listener's eardrums. This requires the acoustical features of the recordin...

journal_title：Scientific reports

authors： Gil-Carvajal JC,Cubick J,Santurette S,Dau T

更新日期：2016-11-17 00:00:00