Substances injected at the Sydney supervised injecting facility: A chemical analysis of used injecting equipment and comparison with self-reported drug type.

Abstract:

:Providing information about substances injected can reduce the negative impact of illicit drug consumption and support people who inject drugs to make informed decisions. In Australia, information about drugs injected relies largely on periodic self-report surveys. For the first time, the analysis of the residual content of used injecting equipment was conducted in a supervised injecting facility (SIF) located in Sydney, Australia. The aim was to gain a better understanding of the substances injected by clients through: (1) chemical analyses of the content of used syringes; (2) comparison of these results with clients' self-reported drug use; and (3) assessing the usefulness of analysing other injecting equipment to detect substances used. During one week in February 2019, syringes and other injecting equipment were collected at the Sydney SIF. Their residual content was analysed by gas-chromatography/mass-spectrometry. Heroin was the most commonly detected substance (present in 51% of syringes), followed by methamphetamine (22%) and oxycodone (10%). In addition to the main psychoactive substance, cutting agents reported in the literature were also detected in used syringes. The main psychoactive substance identified by laboratory analysis reliably corresponded with users' self-reported drug type. Analytical confirmation of substances injected allows for the provision of better targeted harm reduction messaging based on timely and objective data. The approach used is amenable to clients and feasible in the Australian SIF context. Upscaling and wider implementation could be done through Needle and Syringe Programs, and would support the early detection of harmful substances entering drug markets and better inform harm reduction strategies.

journal_name

Drug Alcohol Depend

authors

Lefrancois E,Belackova V,Silins E,Latimer J,Jauncey M,Shimmon R,Mozaner Bordin D,Augsburger M,Esseiva P,Roux C,Morelato M

doi

10.1016/j.drugalcdep.2020.107909

subject

Has Abstract

pub_date

2020-04-01 00:00:00

pages

107909

eissn

0376-8716

issn

1879-0046

pii

S0376-8716(20)30074-0

journal_volume

209

pub_type

杂志文章
  • Efficacy of brief motivational intervention in reducing binge drinking in young men: A randomized controlled trial.

    abstract:BACKGROUND:Brief motivational intervention (BMI) is one of the few effective strategies targeting alcohol consumption, but has not been tested in young men in the community. We evaluated the efficacy of BMI in reducing alcohol use and related problems among binge drinkers and in maintaining low-risk drinking among non-...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.drugalcdep.2010.07.009

    authors: Daeppen JB,Bertholet N,Gaume J,Fortini C,Faouzi M,Gmel G

    更新日期:2011-01-01 00:00:00

  • Acute alcohol intake alters resting state functional connectivity of nucleus accumbens with pain-related corticolimbic structures.

    abstract:BACKGROUND:The nucleus accumbens (NAc) is a ventral striatal structure underlying reward, reinforcement, and motivation, with extensive anatomic and functional connections to a wide range of affective processing structures (medial prefrontal cortex (mPFC), amygdala, and insula). Characterizing how acute alcohol intake ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2019.107811

    authors: Boissoneault J,Stennett B,Robinson ME

    更新日期:2020-02-01 00:00:00

  • High uptake of naloxone-based overdose prevention training among previously incarcerated syringe-exchange program participants.

    abstract:BACKGROUND:Incarceration is common among people who inject drugs. Prior research has shown that incarceration is a marker of elevated risk for opioid overdose, suggesting that the criminal justice system may be an important, under-utilized venue for implementing overdose prevention strategies. To better understand the ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2015.06.023

    authors: Barocas JA,Baker L,Hull SJ,Stokes S,Westergaard RP

    更新日期:2015-09-01 00:00:00

  • In vivo effects of 3,4-methylenedioxymethamphetamine (MDMA) and its deuterated form in rodents: Drug discrimination and thermoregulation.

    abstract:BACKGROUND:Recent clinical studies support the use of 3,4-methylenedioxymethamphetamine (MDMA) as an adjunct treatment for posttraumatic stress disorder (PTSD). Despite these promising findings, MDMA administration in controlled settings can increase blood pressure, heart rate, and body temperature. Previous studies in...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2020.107850

    authors: Berquist MD,Leth-Petersen S,Kristensen JL,Fantegrossi WE

    更新日期:2020-03-01 00:00:00

  • Subjective, cognitive/psychomotor, and physiological effects of aripiprazole in Chinese light and heavy smokers.

    abstract:BACKGROUND:Drug addiction researchers have begun to study dopamine partial agonists as potential therapeutic agents. The partial dopamine D(2) receptor agonist aripiprazole has recently been tested as a treatment for stimulant and alcohol dependence in both animal and clinical studies. METHODS:A randomized and placebo...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.drugalcdep.2008.10.024

    authors: Liu Y,Sun HQ,Bao YP,Li SX,Beveridge TJ,Di XL,Yang FD,Lu L

    更新日期:2009-04-01 00:00:00

  • Relationships between drinking quantity and frequency and behavioral and hippocampal BOLD responses during working memory performance involving allocentric spatial navigation in college students.

    abstract:BACKGROUND:Quantity and frequency of drinking may be used to effectively quantify the severity of alcohol-use. Drinking-severity has been related to neurocognitive impairments in such domains as spatial working memory (SWM). Youth drinking has been associated with altered neurofunctional underpinnings of SWM. The curre...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2019.03.030

    authors: Banz BC,Worhunsky PD,Pittman BP,Astur RS,Tennen HA,Raskin SA,Austad CS,Wood RM,Fallahi CR,Potenza MN,Pearlson GD

    更新日期:2019-08-01 00:00:00

  • The impact of an alcohol harm reduction intervention on interpersonal violence and engagement in sex work among female sex workers in Mombasa, Kenya: Results from a randomized controlled trial.

    abstract:AIMS:To evaluate whether an alcohol harm reduction intervention was associated with reduced interpersonal violence or engagement in sex work among female sex workers (FSWs) in Mombasa, Kenya. DESIGN:Randomized controlled trial. SETTING:HIV prevention drop-in centers in Mombasa, Kenya. PARTICIPANTS:818 women 18 or ol...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.drugalcdep.2015.12.037

    authors: Parcesepe AM,L Engle KL,Martin SL,Green S,Sinkele W,Suchindran C,Speizer IS,Mwarogo P,Kingola N

    更新日期:2016-04-01 00:00:00

  • Epidemiological survey of the use and abuse of agonist-antagonist analgesics in the Western Pacific region.

    abstract::Epidemiological studies are carried out by the National Drug Research Centre, Malaysia on various aspects of drug use and abuse. One of the groups of substances studied are the opioid agonist-antagonists. The study utilised information submitted to international agencies and obtained through a questionnaire survey. Th...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(87)90009-3

    authors: Navaratnam V

    更新日期:1987-12-01 00:00:00

  • Cross-border drug injection relationships among injection drug users in Tijuana, Mexico.

    abstract:BACKGROUND:International borders are unique social and environmental contexts characterized by high levels of mobility. Among drug users, mobility increases risk for human immunodeficiency virus (HIV) in part through its effects on the social environment. However, the social dynamics of drug users living in border regi...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2010.08.009

    authors: Wagner KD,Pollini RA,Patterson TL,Lozada R,Ojeda VD,Brouwer KC,Vera A,Volkmann TA,Strathdee SA

    更新日期:2011-01-15 00:00:00

  • Suspected determinants of enrollment into detoxification and methadone maintenance treatment among injecting drug users.

    abstract::Our primary aim in this study has been to evaluate selected conditions thought to influence the entry of injecting drug users (IDU) into detoxification and methadone maintenance programs, making use of a prospective study design to strengthen a cross-sectional investigation of these conditions. To begin our investigat...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(94)90095-7

    authors: Schütz CG,Rapiti E,Vlahov D,Anthony JC

    更新日期:1994-10-01 00:00:00

  • A retrospective review of unintentional opioid overdose risk and mitigating factors among acutely injured trauma patients.

    abstract:BACKGROUND:Opioid medication to treat acutely injured patients is usual care in trauma settings. A higher prevalence of alcohol and other substance misuse in this population compared to the general population increases the vulnerability of such patients to both misuse of their prescribed opioids, and also unintentional...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.drugalcdep.2017.04.030

    authors: Baird J,Faul M,Green TC,Howland J,Adams CA,George A,Mello MJ

    更新日期:2017-09-01 00:00:00

  • Efficacy of the Community Reinforcement and Family Training for concerned significant others of treatment-refusing individuals with alcohol dependence: A randomized controlled trial.

    abstract:BACKGROUND:The Community Reinforcement and Family Training (CRAFT) is a promising approach for Concerned Significant Others (CSOs) of alcohol-dependent individuals (ADI) that aims to engage treatment-refusing patients in alcohol treatment and to improve CSO functioning. To date, only two randomized controlled trials (R...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.drugalcdep.2016.04.015

    authors: Bischof G,Iwen J,Freyer-Adam J,Rumpf HJ

    更新日期:2016-06-01 00:00:00

  • Treatment of adolescent tobacco smokers: issues and opportunities for exposure reduction approaches.

    abstract::The cycle of tobacco dependence typically begins with the initiation of tobacco use during adolescence. Many teenagers try to quit smoking, fail and subsequently desire treatment for their tobacco dependence. Adolescents do not currently benefit from the same level of societal support for quit attempts as adults, and ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,评审

    doi:10.1016/s0376-8716(03)00012-7

    authors: Moolchan ET,Aung AT,Henningfield JE

    更新日期:2003-06-05 00:00:00

  • Sex differences in drug use among polysubstance users.

    abstract:BACKGROUND:Available evidence indicates women with substance use disorders may experience more rapid progression through usage milestones (telescoping). The few investigations of sex differences in treatment-seeking populations often focus on single substances and typically do not account for significant polysubstance ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2014.10.003

    authors: Lewis B,Hoffman LA,Nixon SJ

    更新日期:2014-12-01 00:00:00

  • Patterns of drug use amongst Malaysian secondary schoolchildren.

    abstract::A representative sampling of the secondary school population of two states of Malaysia (sample size 16166) indicated that 11% of students had had experience of drug use. Use of a single drug was the common pattern, with cannabis reported most often by older students, and sedatives most often by younger students. A qua...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(80)90163-5

    authors: Spencer C,Navaratnam V

    更新日期:1980-05-01 00:00:00

  • Effect of variation in BDNF Val(66)Met polymorphism, smoking, and nicotine dependence on symptom severity of depressive and anxiety disorders.

    abstract:BACKGROUND:Smoking, especially nicotine dependence is associated with more severe symptoms of depression and anxiety disorders. However, the mechanisms underlying this association are unclear. We investigated the effect of brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism on the severity of depressive an...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2014.12.032

    authors: Jamal M,Van der Does W,Penninx BW

    更新日期:2015-03-01 00:00:00

  • Effects of three monoamine uptake inhibitors on behavior maintained by cocaine or food presentation in rhesus monkeys.

    abstract::Rhesus monkeys (n = 6) were surgically prepared with double lumen i.v. catheters and the effects of continuous infusion of the monoamine reuptake blockers mazindol, sertraline and fluoxetine were examined on behavior maintained by food presentation or i.v. cocaine injections. Under baseline conditions, lever pressing ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(93)90067-z

    authors: Kleven MS,Woolverton WL

    更新日期:1993-01-01 00:00:00

  • Short term impact of same intensity but different duration interventions for cannabis users.

    abstract::The present study evaluates the efficacy of a brief intervention for cannabis users. A randomized controlled trial compared 3 conditions: 4 weekly individual sessions of motivational interviewing and relapse prevention over 1 month (1MIRP); the same 4 sessions over 3 months (3MIRP), and delayed treatment control (DTC)...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.drugalcdep.2007.02.019

    authors: Jungerman FS,Andreoni S,Laranjeira R

    更新日期:2007-10-08 00:00:00

  • Substance abuse and white matter: Findings, limitations, and future of diffusion tensor imaging research.

    abstract::Individuals who abuse substances often differ from nonusers in their brain structure. Substance abuse and addiction is often associated with atrophy and pathology of grey matter, but much less is known about the role of white matter, which constitutes over half of human brain volume. Diffusion tensor imaging (DTI), a ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,评审

    doi:10.1016/j.drugalcdep.2019.02.005

    authors: Hampton WH,Hanik IM,Olson IR

    更新日期:2019-04-01 00:00:00

  • Cognitive remediation improves executive functions, self-regulation and quality of life in residents of a substance use disorder therapeutic community.

    abstract:BACKGROUND:Executive dysfunction is common in substance use disorder (SUD) populations and hinders treatment. We previously found that 50% of residents in SUD therapeutic communities had been hospitalized for head injuries; this was a significant determinant of cognitive impairment. The current study aimed to establish...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2017.04.023

    authors: Marceau EM,Berry J,Lunn J,Kelly PJ,Solowij N

    更新日期:2017-09-01 00:00:00

  • Needle sharing in regular sexual relationships: an examination of serodiscordance, drug using practices, and the gendered character of injecting.

    abstract:BACKGROUND:This paper examines correlates of needle and other equipment sharing among injecting drug users (IDU) in regular heterosexual relationships. METHODS:A cross-sectional survey collected data from people obtaining sterile needles and syringes from pharmacies in New South Wales, Australia. 181 IDU in regular he...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2009.10.007

    authors: Bryant J,Brener L,Hull P,Treloar C

    更新日期:2010-03-01 00:00:00

  • Adolescent treatment admissions for marijuana following recreational legalization in Colorado and Washington.

    abstract:INTRODUCTION:There is concern that recreational marijuana legalization (RML) may lead to increased cannabis use disorder (CUD) among youth due to increased marijuana use. This study investigates whether adolescent substance use disorder treatment admissions for marijuana use increased in Colorado and Washington followi...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2020.107960

    authors: Mennis J,Stahler GJ

    更新日期:2020-05-01 00:00:00

  • Respondent-driven sampling to assess characteristics and estimate the number of injection drug users in Bangkok, Thailand.

    abstract:BACKGROUND:Since early in Thailand's HIV epidemic, HIV seroprevalence among injection drug users (IDUs) in Bangkok has been around 40%. As Thailand moves to strengthen HIV prevention and care programs for Bangkok IDUs, information on current patterns of drug use and an estimate of the size and composition of the IDU po...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2007.03.013

    authors: Wattana W,van Griensven F,Rhucharoenpornpanich O,Manopaiboon C,Thienkrua W,Bannatham R,Fox K,Mock PA,Tappero JW,Levine WC

    更新日期:2007-10-08 00:00:00

  • Characteristics of benzodiazepine abuse in methadone maintenance treatment patients: a 1 year prospective study in an Israeli clinic.

    abstract::We aimed to study the prevalence patterns and course of benzodiazepine (BZD) abuse in an Israeli methadone maintenance (MMT) clinic using repeated random observed urine analysis as well as self-report data. Lifetime and current prevalence of BZD abuse were found in 66.3 and 50.8% patients, respectively. It was found t...

    journal_title:Drug and alcohol dependence

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0376-8716(98)00175-6

    authors: Gelkopf M,Bleich A,Hayward R,Bodner G,Adelson M

    更新日期:1999-06-01 00:00:00

  • Associations between polysubstance use and psychiatric problems in a criminal justice population in Sweden.

    abstract:BACKGROUND:Polysubstance use is common in substance users, and may complicate their clinical course. This study, in a criminal justice setting in Sweden, examines the association between the number of concurrently used substance types and psychiatric symptoms during 30 days before incarceration, while controlling for b...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2011.02.014

    authors: Hakansson A,Schlyter F,Berglund M

    更新日期:2011-10-01 00:00:00

  • Racial and gender inequities in the implementation of a cannabis criminal justice diversion program in a large and diverse metropolitan county of the USA.

    abstract:BACKGROUND:Diversion programs are considered alternatives to the arrest and incarceration of non-violent drug offenders, including those found in possession of smaller amounts of cannabis in states with prohibitive laws. Despite the progressive nature of such programs, the inability to complete diversion program requir...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2020.108316

    authors: Sanchez HF,Orr MF,Wang A,Cano MÁ,Vaughan EL,Harvey LM,Essa S,Torbati A,Clark US,Fagundes CP,de Dios MA

    更新日期:2020-11-01 00:00:00

  • Exploring the use and non-use of marijuana as reasoned actions: an application of Fishbein and Ajzen's methodology.

    abstract::Fishbein and Ajzen's methodology can predict behaviour on the basis of questionnaire measures of attitudes toward the specific act and the subjective norms with respect to that behaviour which the individual experiences. In the present study this methodology was used to differentiate between the non-users, experimente...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(83)90081-9

    authors: Budd R,Bleiker S,Spencer C

    更新日期:1983-04-01 00:00:00

  • Adverse childhood experiences and MSM marijuana use.

    abstract:BACKGROUND:Past research identified individuals who experienced adverse childhood experiences (ACEs) are at a higher risk of drug use. There is evidence to suggest that identifying as a man who has sex with other men (MSM) may increase the likelihood of drug use when adverse childhood experiences are prevalent. However...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2019.01.024

    authors: Giano Z,Hubach RD,Currin JM,Wheeler DL

    更新日期:2019-05-01 00:00:00

  • Buprenorphine in primary care: risk factors for treatment injection and implications for clinical management.

    abstract:AIMS:Though the introduction of office-based buprenorphine has greatly contributed to stem the HIV epidemic since 1995, concerns have been raised about the intravenous use of buprenorphine even in patients on substitution treatment. The aim of this study was to identify which factors are predictive of buprenorphine inj...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2008.03.025

    authors: Roux P,Villes V,Blanche J,Bry D,Spire B,Feroni I,Carrieri MP

    更新日期:2008-09-01 00:00:00

  • Dronabinol and lofexidine for cannabis use disorder: A randomized, double-blind, placebo-controlled trial.

    abstract:BACKGROUND:Cannabis use disorder is associated with substantial morbidity and, after alcohol, is the most common drug bringing adolescents and adults into treatment. At present, there are no FDA-approved medications for cannabis use disorder. Combined pharmacologic interventions might be particularly useful in mitigati...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.drugalcdep.2015.11.025

    authors: Levin FR,Mariani JJ,Pavlicova M,Brooks D,Glass A,Mahony A,Nunes EV,Bisaga A,Dakwar E,Carpenter KM,Sullivan MA,Choi JC

    更新日期:2016-02-01 00:00:00