Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Plint T,Longstaffe FJ,Zazula Gdoi
10.1038/s41598-020-61338-ysubject
Has Abstractpub_date
2020-03-06 00:00:00pages
4533issue
1issn
2045-2322pii
10.1038/s41598-020-61338-yjournal_volume
10pub_type
已发布勘误abstract::The increased risk of cardiovascular events in older men is multifactorial, but the significant reduction of testosterone levels has been involved. As this hormone regulates the expression of TFPI by unknown mechanisms, we aimed to evaluate the role of miRNAs in the regulation of TFPIα expression under normal conditio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43500
更新日期:2017-02-27 00:00:00
abstract::Tradional antireflection coatings composed of dielectric layers usually require the thickness to be larger than quarter wavelength. Here, we demonstrate that materials with permittivity or permeability dominated by imaginary parts, i.e. lossy or gain media, can realize non-resonant antireflection coatings in deep sub-...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28681
更新日期:2016-06-28 00:00:00
abstract::Associations between cognitive decline and cerebral microbleeds (CMBs) have received increasing attention. An association between CMB distribution (deep or lobar) and cognitive decline has been reported, but these findings are controversial. We investigated the association between magnetic resonance imaging (MRI) find...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73404-6
更新日期:2020-10-02 00:00:00
abstract::This study measured the effects of vitamin D (VD) supplementation on the underlying molecular pathways involved in renal and testicular damage induced by lead (Pb) toxicity. Thirty two adult male Wistar rats were divided equally into four groups that were treated individually or simultaneously, except the negative con...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23258-w
更新日期:2018-03-19 00:00:00
abstract::Fluorescence is widespread in marine organisms but uncommon in terrestrial tetrapods. We here show that many chameleon species have bony tubercles protruding from the skull that are visible through their scales, and fluoresce under UV light. Tubercles arising from bones of the skull displace all dermal layers other th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-19070-7
更新日期:2018-01-15 00:00:00
abstract::We investigated risk factors for postoperative serious adverse events (SAEs) in elderly patients with preoperative chronic hypoxaemia undergone total hip arthroplasty (THA) or hemiarthroplasty and performed an implementation to modify and improve clinical outcome. A retrospective medical record review was performed to...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-55607-8
更新日期:2019-12-16 00:00:00
abstract::Safe management of high level nuclear waste is a worldwide significant issue for which vitrification has been selected by many countries. There exists a crucial need for improving our understanding of the ageing of the glass under irradiation. While external irradiation by ions provides a rapid simulation of damage in...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25499
更新日期:2016-05-05 00:00:00
abstract::Two decades ago, a phenomenon resembling Landau damping was described in the synchronization of globally coupled oscillators: the evidence of a regime where the order parameter decays when linear theory predicts neutral stability for the incoherent state. We here show that such an effect is far more generic, as soon a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18235
更新日期:2015-12-14 00:00:00
abstract::Tumors are characterized by a rigid, highly cross-linked extracellular matrix (ECM), which impedes homogeneous drug distribution and potentially protects malignant cells from exposure to therapeutics. Lysyl oxidases are major contributors to tissue stiffness and the elevated expression of these enzymes observed in mos...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep17576
更新日期:2015-12-01 00:00:00
abstract::Biofertilizer production and application for sustainable agriculture is already a reality. The methods for biofertilizers delivery in crop fields are diverse. Although foliar spray is gaining wide acceptance, little is known about the influence that the biochemical features of leaves have on the microbial colonization...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65314-4
更新日期:2020-05-21 00:00:00
abstract::The use of microwave (MW) irradiation to increase the rate of chemical reactions has attracted much attention recently in nearly all fields of chemistry due to substantial enhancements in reaction rates. However, the intrinsic nature of the effects of MW irradiation on chemical reactions remains unclear. Herein, the h...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25149
更新日期:2016-04-27 00:00:00
abstract::Anti-EGFR antibodies are effective in therapies for late-stage colorectal cancer (CRC); however, many tumours are unresponsive or develop resistance. We performed genomic analysis of intrinsic and acquired resistance to anti-EGFR therapy in prospectively collected tumour samples from 25 CRC patients receiving cetuxima...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-51981-5
更新日期:2019-10-25 00:00:00
abstract::Internet gaming disorder (IGD) has been conceptualized as a behavioral addiction and shares clinical, neuropsychological, and personality characteristics with alcohol use disorder (AUD), but IGD dose not entail brain exposure to toxic agents, which renders it different from AUD. To achieve a clear understanding of the...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06057-7
更新日期:2017-07-18 00:00:00
abstract::Deriving cell populations from human embryonic stem cells (hESCs) for cell-based therapy is considered a promising strategy to achieve functional cells, yet its translation to clinical practice depends on achieving fully defined differentiated cells. In this work, we generated a miRNA-responsive lethal mRNA construct ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50899-2
更新日期:2019-10-10 00:00:00
abstract::In order to ensure successful development, cells of the early mammalian embryo must differentiate to either trophectoderm (TE) or inner cell mass (ICM), followed by epiblast (EPI) or primitive endoderm (PE) specification within the ICM. Here, we deciphered the mechanism that assures the correct order of these sequenti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15427-0
更新日期:2017-11-09 00:00:00
abstract::Structural materials used for safety critical applications require high strength and simultaneously high resistance against crack growth, referred to as damage tolerance. However, the two properties typically exclude each other and research efforts towards ever stronger materials are hampered by drastic loss of fractu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33228
更新日期:2016-09-14 00:00:00
abstract::We have studied an expansion behavior of pressurized bubbles at the orifice of a capillary inserted in gelator-solvent (agarose-water) mixtures as a function of the gelator concentration in which the phase transition points are included. The pressure (P) -dependence of the radius of the curvature (R) of the bubbles mo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58905-8
更新日期:2020-02-14 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-68818-1
更新日期:2020-08-10 00:00:00
abstract::We investigated the cognitive and behavioral profile of three distinct groups of epilepsies with a genetic background for intergroup differences: (1) idiopathic/genetic generalized epilepsies (IGE/GGE group); (2) idiopathic focal epilepsies (IFE group); and (3) epilepsies with proven or strongly suggested monogenic or...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-78218-0
更新日期:2020-12-09 00:00:00
abstract::The objective of this study was to investigate the effects of slightly elevated atmospheric temperature in the spring on photosynthetic products in wheat seedlings and on organic compounds and biological activity in rhizosphere soil under cadmium (Cd) stress. Elevated temperature was associated with increased soluble ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14426
更新日期:2015-09-23 00:00:00
abstract::Periodontal (gum) disease is a highly prevalent infection and inflammation accounting for the majority of tooth loss in adult population worldwide. Porphyromonas gingivalis is a keystone periodontal pathogen and its lipopolysaccharide (PgLPS) acts as a major virulence attribute to the disease. Herein, we deciphered th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29829
更新日期:2016-08-19 00:00:00
abstract::Pluripotent stem cells (PSCs) have various degrees of pluripotency, which necessitates selection of PSCs with high pluripotency before their application to regenerative medicine. However, the quality control processes for PSCs are costly and time-consuming, and it is essential to develop inexpensive and less laborious...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37779-x
更新日期:2019-02-11 00:00:00
abstract::Sideroflexin4 (SFXN4) is a member of a family of nuclear-encoded mitochondrial proteins. Rare germline mutations in SFXN4 lead to phenotypic characteristics of mitochondrial disease including impaired mitochondrial respiration and hematopoetic abnormalities. We sought to explore the function of this protein. We show t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-55907-z
更新日期:2019-12-23 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-65967-1
更新日期:2020-06-04 00:00:00
abstract::Elucidation of temperature tolerance mechanisms in yeast is essential for enhancing cellular robustness of strains, providing more economically and sustainable processes. We investigated the differential responses of three distinct Saccharomyces cerevisiae strains, an industrial wine strain, ADY5, a laboratory strain,...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-77846-w
更新日期:2020-12-18 00:00:00
abstract::Frequent self-monitoring of blood glucose (SMBG) is the only accurate method available for insulin dose titration in patients with T1DM. Professional continuous glucose monitoring (p-CGM) is blinded recording of glucose trends over 5-7 days and helps physicians to guide insulin titration to patient. This study was pla...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-42555-6
更新日期:2019-04-16 00:00:00
abstract::Oceanic physics at fine scale; e.g. eddies, fronts, filaments; are notoriously difficult to sample. However, an increasing number of theoretical approaches hypothesize that these processes affect phytoplankton diversity which have cascading effects on regional ecosystems. In 2015, we targeted the Iroise Sea (France) a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82071-0
更新日期:2021-01-29 00:00:00
abstract::The dispensing of tiny droplets is a basic and crucial process in a myriad of applications, such as DNA/protein microarray, cell cultures, chemical synthesis of microparticles, and digital microfluidics. This work systematically demonstrates droplet dispensing into immiscible fluids through electric charge concentrati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31901
更新日期:2016-08-18 00:00:00
abstract::Recently, 5-hydroxymethylcytosine patterning across the tumor genome was considered as a hallmark of cancer development and progression. However, locus-specific difference of hydroxymethylation between colorectal cancer and normal tissue is unknown. In this study, we performed a newly developed method, HMST-seq, to pr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31826
更新日期:2016-08-22 00:00:00
abstract::In the present work, the mechanisms involved in the recently reported antiviral activity of zebrafish C-reactive protein-like protein (CRP1-7) against the spring viraemia of carp rhabdovirus (SVCV) in fish are explored. The results neither indicate blocking of the attachment or the binding step of the viral replicatio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-57501-0
更新日期:2020-01-17 00:00:00