Abstract:
:A novel Vibrio alginolyticus phage, VAP7, was isolated from seawater collected from Sanya, Hainan province, China. Whole-genome sequencing analysis revealed that phage VAP7 has a linear, double-stranded DNA genome of 144,685 bp with an average G+C content of 41.9% and a high degree of sequence similarity to Vibrio phage VP-1. Annotation results identified 193 open reading frames and one transfer RNA-encoding gene in the phage genome. The morphology and the results of phylogenetic analysis suggest that VAP7 should be classified as a new member of the family Ackermannviridae. Moreover, phage VAP7 grew over a wide pH (5.0-10.0) and temperature (4-40 °C) range. Host-range experiments revealed that VAP7 could infect 31 Vibrio alginolyticus strains. Thus, VAP7 infecting Vibrio alginolyticus strains represents a potential new candidate for use in phage therapy.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Gao M,Qin Y,Fan H,Zhang X,Li P,Liu H,Pei G,Mi Z,Xu X,Tong Y,Bai Cdoi
10.1007/s00705-020-04535-4subject
Has Abstractpub_date
2020-04-01 00:00:00pages
947-953issue
4eissn
0304-8608issn
1432-8798pii
10.1007/s00705-020-04535-4journal_volume
165pub_type
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