Abstract:
PURPOSE:We examined (1) if child maltreatment (CM) is associated with lower health-related quality of life (HRQoL) and fewer quality-adjusted life years (QALY) over a 9-year follow-up of midlife women and (2) if adulthood psychosocial mediators could explain these associations. METHODS:Women (n = 342) completed the Childhood Trauma Questionnaire. Longitudinal HRQoL and QALY outcomes measured at five study visits include 36-item Short-Form Health Survey mental component score and physical component score and the Short Form-6 Dimension health index. Aims 1 and 2 were investigated by generalized estimating equations and sequential structural nested mean models, respectively. RESULTS:Twenty percent reported 2+ CM types. Compared with women without CM, women who experienced 2+ CM types reported 5- and 4-points lower scores in mental component score and physical component score, respectively, and 28 fewer healthy days per year in QALY. Low optimism, sleep problems, and low social support each explained greater than 10% of the relationship between 2+ CM and HRQoL and QALY over time. CONCLUSIONS:CM is a life-course social determinant of HRQoL and QALY throughout midlife, particularly in women who experienced 2+ CM types. Several mediators are modifiable and could be targets of interventions to mitigate the negative impact of CM on midlife HRQoL and QALY in women.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Lin HS,Naimi AI,Brooks MM,Richardson GA,Burke JG,Bromberger JTdoi
10.1016/j.annepidem.2020.01.005subject
Has Abstractpub_date
2020-03-01 00:00:00pages
58-65eissn
1047-2797issn
1873-2585pii
S1047-2797(19)30421-1journal_volume
43pub_type
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:2008-02-01 00:00:00
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journal_title:Annals of epidemiology
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2017.09.010
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journal_title:Annals of epidemiology
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journal_title:Annals of epidemiology
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更新日期:2013-06-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2008.04.005
更新日期:2008-08-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:2005-04-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2005.06.055
更新日期:2006-03-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2019.10.005
更新日期:2019-12-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2020.04.007
更新日期:2020-08-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2004.03.007
更新日期:2005-01-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2013.02.006
更新日期:2013-05-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2004.09.003
更新日期:2005-05-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2004.12.004
更新日期:2005-07-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2019.12.003
更新日期:2020-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/1047-2797(92)90013-g
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Annals of epidemiology
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doi:10.1016/j.annepidem.2009.03.007
更新日期:2009-06-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
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更新日期:2015-03-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2011.10.006
更新日期:2012-01-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.annepidem.2007.01.005
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:To investigate the possible association between ibuprofen use and dermatologic superinfections among children with recent varicella infection. METHODS:A retrospective cohort study of children in Harvard Pilgrim Health Care, a health maintenance organization in New England, was conducted. Outcomes and exposures...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(97)00040-9
更新日期:1997-10-01 00:00:00
abstract::PURPOSE: Evaluating the impact of population-based rehabilitation interventions for work-related low back disorders (WR-LBD) requires job exposure factors to be considered as time-varying covariates. The role of job factors in recovery has not been well-established as most studies are based upon clinic samples, not wo...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(00)00165-4
更新日期:2000-10-01 00:00:00
abstract::In the context of generalized human immunodeficiency virus (HIV) epidemics, there has been limited recent investment in HIV surveillance and prevention programming for key populations including female sex workers. Often implicit in the decision to limit investment in these epidemic settings are assumptions including t...
journal_title:Annals of epidemiology
pub_type: 杂志文章,评审
doi:10.1016/j.annepidem.2016.06.004
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:We estimated female and male incident AIDS diagnosis rates (IARs) among people who inject drugs (PWID) in U.S. metropolitan statistical areas (MSAs) over time to assess whether declines in IARs varied by sex after combination antiretroviral therapy (cART) dissemination. METHODS:We compared IARs and 95% confide...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2015.01.006
更新日期:2015-04-01 00:00:00
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journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2013.02.002
更新日期:2013-05-01 00:00:00