The association between NAT2 acetylator status and adverse drug reactions of sulfasalazine: a systematic review and meta-analysis.

abstract：:Adverse maternal environments, such as diabetes and obesity, impair placental mitochondrial function, which affects fetal development and offspring long-term health. The underlying mechanisms and effective interventions to abrogate such effect remain unclear. Our previous studies demonstrated impaired mitochondrial bi...

journal_title：Scientific reports

authors： Jiang S,Teague AM,Tryggestad JB,Jensen ME,Chernausek SD

更新日期：2020-05-20 00:00:00

abstract：:We report low-temperature solution-processed p-CuO nanorods (NRs)/n-ZnO NRs heterojunction light emitting diode (LED), exploiting the native point defects of ZnO NRs. ZnO NRs were synthesized at 90 °C by using hydrothermal method while CuO NRs were synthesized at 100 °C by using microwave reaction system. The electric...

journal_title：Scientific reports

authors： Biswas P,Baek SD,Lee SH,Park JH,Lee SJ,Lee TI,Myoung JM

更新日期：2015-12-09 00:00:00

abstract：:Gene essentiality changes are crucial for organismal evolution. However, it is unclear how essentiality of orthologs varies across species. We investigated the underlying mechanism of gene essentiality changes between yeast and mouse based on the framework of network evolution and comparative genomic analysis. We foun...

journal_title：Scientific reports

authors： Kim J,Kim I,Han SK,Bowie JU,Kim S

更新日期：2012-01-01 00:00:00

abstract：:This work reports the oxygen reduction reaction (ORR) kinetics of metal nanoparticle catalysts between 500 and 600 °C at low oxygen partial pressures. Ex situ and in situ TEM measurements demonstrate catalyzed nanowire growth initially follows linear kinetics; characteristic of being ORR rate limited. The ORR rates of...

journal_title：Scientific reports

authors： Sun K,Xue J,Tai K,Dillon SJ

更新日期：2017-08-01 00:00:00

abstract：:MBL2 gene encodes mannose-binding lectin, is a member of innate immune system. Earlier studies revealed that MBL2 gene variants, rs1800451, rs1800450, rs5030737, rs7096206, rs11003125 and rs7095891 are associated with impaired serum level and susceptibility to TB, but their results are inconsistent. A meta-analysis wa...

journal_title：Scientific reports

authors： Areeshi MY,Mandal RK,Akhter N,Dar SA,Jawed A,Wahid M,Mahto H,Panda AK,Lohani M,Haque S

更新日期：2016-11-23 00:00:00

abstract：:PAP80-2a, purified from Pholiota adiposa mycelia, is a polysaccharide exhibiting prominent antitumor effects. However, the yield of PAP80-2a was low and its structure has not been characterized, impeding the exploration of its structure-function relationship, thus influencing the development of oral drugs for antitumo...

journal_title：Scientific reports

authors： Zou Y,Du F,Hu Q,Wang H

更新日期：2019-02-11 00:00:00

abstract：:Transgenic sexing strains (TSS) that carry conditional female lethal genes are advantageous for genetic control programs based on the sterile insect technique (SIT). It is desirable if females die early in development as larval diet is a major cost for mass production facilities. This can be achieved by using a gene p...

journal_title：Scientific reports

authors： Yan Y,Linger RJ,Scott MJ

更新日期：2017-05-31 00:00:00

abstract：:Mixed Plasmodium malaria infections can lead to severe malaria. This systematic review and meta-analysis aimed to explore the prevalence of severe mixed Plasmodium malaria infection and to compare it with the prevalence of severe P. falciparum malaria mono-infection across the included studies. Original English-langua...

journal_title：Scientific reports

authors： Kotepui M,Kotepui KU,De Jesus Milanez G,Masangkay FR

更新日期：2020-07-06 00:00:00

abstract：:Conventional spin-singlet Cooper pairs convert into spin-triplet pairs in ferromagnetic Josephson junctions in which the superconductor/ferromagnet interfaces (S/F) are magnetically inhomogeneous. Although much of the theoretical work describing this triplet proximity effect has considered ideal junctions with magneti...

journal_title：Scientific reports

authors： Robinson JW,Chiodi F,Egilmez M,Halász GB,Blamire MG

更新日期：2012-01-01 00:00:00

abstract：:Low back pain (LBP) is a widespread debilitating disorder of significant socio-economic importance and intervertebral disc (IVD) degeneration has been implicated in its pathogenesis. Despite its high prevalence the underlying causes of LBP and IVD degeneration are not well understood. Recent work in musculoskeletal de...

journal_title：Scientific reports

authors： Wiet MG,Piscioneri A,Khan SN,Ballinger MN,Hoyland JA,Purmessur D

更新日期：2017-10-02 00:00:00

abstract：:Herein, by growing mono dispersed gold nanoparticles (MNPAu) on the surface of polystyrene (PS)/nanogold (Au) core-shell composites (PS@Au), we successfully synthesized a micron-sized gold cage (2.6-10.7 μm), referred to as PS@Au@MNPAu for the first time. The new micron-gold cage materials exhibit broadband absorption...

journal_title：Scientific reports

authors： Dong S,Yi L,Cheng L,Li S,Yang W,Wang Z,Jiang S

更新日期：2020-10-06 00:00:00

abstract：:We conducted extensive molecular dynamics simulations to investigate the thermal conductivity of polycrystalline hexagonal boron-nitride (h-BN) films. To this aim, we constructed large atomistic models of polycrystalline h-BN sheets with random and uniform grain configuration. By performing equilibrium molecular dynam...

journal_title：Scientific reports

authors： Mortazavi B,Pereira LFC,Jiang JW,Rabczuk T

更新日期：2015-08-19 00:00:00

abstract：:Proteins are of interest in nano-bio electronic devices due to their versatile structures, exquisite functionality and specificity. However, quantum transport measurements produce conflicting results due to technical limitations whereby it is difficult to precisely determine molecular orientation, the nature of the mo...

journal_title：Scientific reports

authors： Sheu SY,Yang DY

更新日期：2017-01-04 00:00:00

abstract：:The interaction of (quasi)particles with a periodic potential arises in various domains of science and engineering, such as solid-state physics, chemical physics, and communication theory. An attractive test ground to investigate this interaction is represented by superconductors with artificial pinning sites, where m...

journal_title：Scientific reports

authors： Dobrovolskiy OV,Huth M,Shklovskij VA,Vovk RV

更新日期：2017-10-23 00:00:00

abstract：:Follicular bronchiolitis (FB) is a rare interstitial lung disease (ILD) and has been reported in diverse clinical contexts. Six FB patients demonstrated by surgical lung biopsy (SLB) were reviewed between 2009 and 2017 from Nanjing Drum Tower Hospital in China. The average age of subjects was 42 years old (range: 31-5...

journal_title：Scientific reports

authors： Lu J,Ma M,Zhao Q,Meng F,Wang D,Cai H,Cao M

更新日期：2018-05-08 00:00:00

abstract：:Pesticides are the main tactics for pest control because they reduce the pest population very fast and their efficiency does not depend on abiotic factors. However, the indiscriminate use of these substances can speed up the development of resistant populations and causing environmental contamination. Therefore, alter...

journal_title：Scientific reports

authors： Campos EVR,Proença PLF,Oliveira JL,Pereira AES,de Morais Ribeiro LN,Fernandes FO,Gonçalves KC,Polanczyk RA,Pasquoto-Stigliani T,Lima R,Melville CC,Della Vechia JF,Andrade DJ,Fraceto LF

更新日期：2018-05-16 00:00:00

abstract：:Using 137Cs and 210Pb dating and multi-proxy evidence from a 41-cm sediment core from Bosten Lake in China, the responses of sediment grain size to environmental changes were reconstructed over the past 150 years. After the end of the Little Ice Age, the climate of the Bosten Lake region became warmer and drier, and t...

journal_title：Scientific reports

authors： Ma L,Abuduwaili J,Liu W

更新日期：2020-01-22 00:00:00

abstract：:The purpose of this study was to investigate a preclinical spectral photon-counting CT (SPCCT) prototype compared to conventional CT for pulmonary imaging. A custom-made lung phantom, including nodules of different sizes and shapes, was scanned with a preclinical SPCCT and a conventional CT in standard and high-resolu...

journal_title：Scientific reports

authors： Kopp FK,Daerr H,Si-Mohamed S,Sauter AP,Ehn S,Fingerle AA,Brendel B,Pfeiffer F,Roessl E,Rummeny EJ,Pfeiffer D,Proksa R,Douek P,Noël PB

更新日期：2018-11-26 00:00:00

abstract：:The cell adhesion molecule neuroplastin (Np) is a novel candidate to influence human intelligence. Np-deficient mice display complex cognitive deficits and reduced levels of Plasma Membrane Ca2+ ATPases (PMCAs), an essential regulator of the intracellular Ca2+ concentration ([iCa2+]) and neuronal activity. We show abu...

journal_title：Scientific reports

authors： Herrera-Molina R,Mlinac-Jerkovic K,Ilic K,Stöber F,Vemula SK,Sandoval M,Milosevic NJ,Simic G,Smalla KH,Goldschmidt J,Bognar SK,Montag D

更新日期：2017-08-04 00:00:00

abstract：:Organic light emitting diodes (OLEDs) operating in the near-infrared spectral region are gaining growing relevance for emerging photonic technologies, such as lab-on-chip platforms for medical diagnostics, flexible self-medicated pads for photodynamic therapy, night vision and plastic-based telecommunications. The ach...

journal_title：Scientific reports

authors： Sassi M,Buccheri N,Rooney M,Botta C,Bruni F,Giovanella U,Brovelli S,Beverina L

更新日期：2016-09-28 00:00:00

abstract：:Vertical vergence is generally associated with one of three mechanisms: vestibular activation during a head tilt, induced by vertical visual disparity, or as a by-product of ocular torsion. However, vertical vergence can also be induced by seemingly unrelated visual conditions, such as optokinetic rotations. This stud...

journal_title：Scientific reports

authors： Wibble T,Pansell T

更新日期：2020-09-23 00:00:00

abstract：:It is well known the thermal properties of three-dimensional (3-D) hybrid graphene (GR)-carbon nanotube (CNT) structures are not superior to that of the individual GR and CNT, however, the 3-D hybrid GR-CNT structures can effectively improve the thermal properties of polymer matrix. Therefore, understanding the therma...

journal_title：Scientific reports

authors： Liu F,Liu X,Hu N,Ning H,Atobe S,Yan C,Mo F,Fu S,Zhang J,Wang Y,Mu X

更新日期：2017-10-31 00:00:00

abstract：:The liver is constantly exposed to dietary antigens, viruses, and bacterial products with inflammatory potential. For decades cellular uptake of virus has been studied in connection with infection, while the few studies designed to look into clearance mechanisms focused mainly on the role of macrophages. In recent yea...

journal_title：Scientific reports

authors： Øie CI,Wolfson DL,Yasunori T,Dumitriu G,Sørensen KK,McCourt PA,Ahluwalia BS,Smedsrød B

更新日期：2020-01-21 00:00:00

abstract：:Glioblastoma multiforme (GBM) is a highly invasive and chemoradioresistant brain malignancy. Temozolomide (TMZ), a DNA-alkylating agent, is effective against GBM and has become the standard first-line drug. However, the mechanism by which TMZ regulates the progression of GBM remains elusive. Here, we demonstrate that ...

journal_title：Scientific reports

authors： Yamaki T,Suenaga Y,Iuchi T,Alagu J,Takatori A,Itami M,Araki A,Ohira M,Inoue M,Kageyama H,Yokoi S,Saeki N,Nakagawara A

更新日期：2013-01-01 00:00:00

abstract：:There is strong in vitro cell survival evidence that the relative biological effectiveness (RBE) of protons is variable, with dependence on factors such as linear energy transfer (LET) and dose. This is coupled with the growing in vivo evidence, from post-treatment image change analysis, of a variable RBE. Despite thi...

journal_title：Scientific reports

authors： Smith EAK,Henthorn NT,Warmenhoven JW,Ingram SP,Aitkenhead AH,Richardson JC,Sitch P,Chadwick AL,Underwood TSA,Merchant MJ,Burnet NG,Kirkby NF,Kirkby KJ,Mackay RI

更新日期：2019-12-27 00:00:00

abstract：:Despite growing acknowledgement of the role of oxidized fatty acids (oxFA) as cellular signaling molecules and in the pathogenesis of disease, developing methods to measure these species in biological samples has proven challenging. Here we describe a novel method utilizing HPLC-ESI-MS/MS to identify and quantify mult...

journal_title：Scientific reports

authors： Ahern KW,Serbulea V,Wingrove CL,Palas ZT,Leitinger N,Harris TE

更新日期：2019-08-01 00:00:00

abstract：:The investigation of chemical and structural dynamics in battery materials is essential to elucidation of structure-property relationships for rational design of advanced battery materials. Spatially resolved techniques, such as scanning/transmission electron microscopy (S/TEM), are widely applied to address this chal...

journal_title：Scientific reports

authors： Lin F,Markus IM,Doeff MM,Xin HL

更新日期：2014-07-16 00:00:00

abstract：:We study universal uncertainty relations and present a method called joint probability distribution diagram to improve the majorization bounds constructed independently in [Phys. Rev. Lett. 111, 230401 (2013)] and [J. Phys. A. 46, 272002 (2013)]. The results give rise to state independent uncertainty relations satisfi...

journal_title：Scientific reports

authors： Li T,Xiao Y,Ma T,Fei SM,Jing N,Li-Jost X,Wang ZX

更新日期：2016-10-24 00:00:00

abstract：:We here describe the dc magnetic field over the human head produced by healthy hair follicles when the scalp is lightly pressed. This phenomenon was briefly reported decades earlier, where a double-planar SQUID (Superconducting Quantum Interference Devices) gradiometer at a single location was used. We here perform a ...

journal_title：Scientific reports

authors： Khan S,Cohen D

更新日期：2019-10-30 00:00:00

abstract：:R-loops are RNA-DNA hybrid sequences that are emerging players in various biological processes, occurring in both prokaryotic and eukaryotic cells. In viruses, R-loop investigation is limited and functional importance is poorly understood. Here, we performed a computational approach to investigate prevalence, distribu...

journal_title：Scientific reports

authors： Wongsurawat T,Gupta A,Jenjaroenpun P,Owens S,Forrest JC,Nookaew I

更新日期：2020-04-14 00:00:00