Abstract：
:Transcranial magnetic stimulation (TMS) may offer a reliable means to characterize significant pathophysiologic and neurochemical aspects of restless legs syndrome (RLS). Namely, TMS has revealed specific patterns of changes in cortical excitability and plasticity, in particular dysfunctional inhibitory mechanisms and sensorimotor integration, which are thought to be part of the pathophysiological mechanisms of RLS rather than reflect a non-specific consequence of sleep architecture alteration. If delivered repetitively, TMS is able to transiently modulate the neural activity of the stimulated and connected areas. Some studies have begun to therapeutically use repetitive TMS (rTMS) to improve sensory and motor disturbances in RLS. High-frequency rTMS applied over the primary motor cortex or the supplementary motor cortex, as well as low-frequency rTMS over the primary somatosensory cortex, seem to have transient beneficial effects. However, further studies with larger patient samples, repeated sessions, an optimized rTMS setup, and clinical follow-up are needed in order to corroborate preliminary results. Thus, we performed a systematic search of all the studies that have used TMS and rTMS techniques in patients with RLS.
journal_name
Sleep Medjournal_title
Sleep medicineauthors
Nardone R,Sebastianelli L,Versace V,Brigo F,Golaszewski S,Pucks-Faes E,Saltuari L,Trinka Edoi
10.1016/j.sleep.2019.12.009subject
Has Abstractpub_date
2020-07-01 00:00:00pages
124-134eissn
1389-9457issn
1878-5506pii
S1389-9457(19)31660-0journal_volume
71pub_type
杂志文章,评审相关文献
SLEEP MEDICINE文献大全abstract：OBJECTIVE AND BACKGROUND:Impaired cerebral blood flow and cerebrovascular reactivity to hypercapnia during wakefulness at rest as well as reduced exercise tolerance have been reported in severe obstructive sleep apnea (OSA) patients. Impaired cerebral oxygenation and hemodynamics can contribute to reduced exercise perf...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2018.06.013
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVE:Nocturnal eating behavior is shared by patients affected by a parasomnia, sleep-related eating disorder (SRED), and several eating disorders such as night eating syndrome (NES) and binge-eating disorder (BED); however, the differential clinical features of these patients have been poorly studied, with persist...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2014.12.020
更新日期：2015-06-01 00:00:00
abstract：OBJECTIVE:To explore the correlates of nocturnal sleep duration, nocturnal sleep variability, and nocturnal sleep problems in a sample of Australian toddlers. METHODS:Participants were 173 toddlers (average age 19.7 ± 4.1 months) from the GET UP! STUDY:Nocturnal sleep duration, nocturnal sleep variability, nap(s) and...
journal_title：Sleep medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.sleep.2018.08.035
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Restless Legs Syndrome (RLS) is characterized by uncomfortable nocturnal sensations in the legs making sedentary activities and sleep difficult, and is thus linked with psychosocial distress. Due to the symptomatology and neurobiology of RLS (disrupting brain iron and dopamine) it is likely that RLS associat...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2018.02.007
更新日期：2018-05-01 00:00:00
abstract：:Lingual thyroid has been reported to cause obstructive sleep apnea (OSA) only once in the literature. We present a case of a 49-year-old nonobese female with a 2-year history of progressive snoring, apneas, snort arousals, and daytime somnolence associated with the sensation of an 'enlarging tongue'. She was found to ...
journal_title：Sleep medicine
pub_type： 杂志文章,评审
doi：10.1016/j.sleep.2004.06.005
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to analyze statistically the number of single leg movements (LMs) forming bilateral LMs during sleep, along with their combined duration, to eventually provide evidence-based data for the adjustment of the current scoring rules defining bilateral LMs. METHODS:Polysomnographic record...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2016.03.018
更新日期：2017-04-01 00:00:00
abstract：INTRODUCTION:We investigated the impact of delayed sleep phase disorder (DSPD) on the daily lives of adolescents and their families. METHOD:In this qualitative study, six adolescents with DSPD, and six parents were given in-depth interviews. Using thematic analysis, we merged open codes into themes that reflected the ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2019.05.022
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND AND PURPOSE:We investigated the frequency of restless legs syndrome (RLS) and sleep disturbance in spinocerebellar ataxia type 6 (SCA6). PATIENTS AND METHODS:Five patients out of three multigenerational SCA6 families underwent a standardized investigation protocol including clinical interview for RLS, neuro...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2006.03.013
更新日期：2006-09-01 00:00:00
abstract：STUDY OBJECTIVES:To examine the associations between screen time, the time spent on different screen devices, and sleep in a sample of Finnish preschool children. METHODS:The current study analyzed cross-sectional data from the DAGIS study carried out in Finland in 2015-2016 on 736 children aged 3-6 years. Parents rep...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2020.11.008
更新日期：2020-11-11 00:00:00
abstract：BACKGROUND:Very few prospective studies examine the relationship between childhood sleep problems and subsequent substance use. In this study, we examined how sleep problems at ages 3-8 predicted onset of alcohol, cigarette, and marijuana use in adolescence. We also investigated the relationships between childhood slee...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2008.06.015
更新日期：2009-08-01 00:00:00
abstract：OBJECTIVE:The aim of the present study was to investigate the impact of sleep on osteoporosis. METHODS:The study used a baseline examination of the Hiroshima Sleep and Healthcare study, which was a cross-sectional and cohort study that addressed the association of sleep habits with lifestyle-related diseases. A total ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2016.06.029
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:Slow wave sleep (SWS) has been theorized as reflecting a homeostatic sleep process and is considered a state of recuperation. SWS is reduced in obstructive sleep apnea (OSA) patients, but SWS has not been specifically studied in respiratory failure patients. The aim of this study is to investigate SWS in pre...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2011.01.007
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:Eveningness tendency and insomnia are common in adolescents, but whether they have an independent or synergistic effect on the risk of psychopathology have remained undefined. The present study aimed to examine eveningness chronotype and insomnia symptoms in relation to mental health and emotional and behavio...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2018.03.025
更新日期：2018-07-01 00:00:00
abstract：:Sleep disturbances are common in extrapyramidal diseases, including not only insomnia but excessive daytime sleepiness and parasomnias. In particular, complaints related to sleep are extremely common among patients affected by Parkinson's disease (PD). The underlying causes may include: patient age, associated illness...
journal_title：Sleep medicine
pub_type： 杂志文章,评审
doi：10.1016/j.sleep.2003.10.012
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVES:To investigate potential delays in endogenous melatonin in individuals with obsessive-compulsive disorder (OCD). METHODS:First, data are presented for 15 individuals with OCD and matched healthy controls. Next, nine additional participants with OCD who did not have matched controls were added, resulting in ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2020.03.021
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:Based on cross-sectional studies, sleep duration has been shown to have a relationship with the prevalence of metabolic syndrome (MS); however, no prospective studies have verified a correlation between the incidence of MS and the gender difference. Herein we prospectively determined the association between M...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2015.03.024
更新日期：2015-08-01 00:00:00
abstract：OBJECTIVE:This study aimed to investigate longitudinal relationships between sleep problems and subtypes of anxiety symptoms among adolescent earthquake survivors. METHODS:Participants were 1573 adolescents (male, 45.8%; mean age at baseline 15.01 years, standard deviation (SD) = 1.26) in the Wenchuan Earthquake Adole...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2018.05.017
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVES:Large prospective studies have established that sleep-disordered breathing (SDB) is associated with an increased incidence of cardiovascular and cerebrovascular diseases. Heterogeneous results have been published about SDB and ischaemic stroke mechanism. The aim of this study was to evaluate the relationship...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2015.07.031
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Cerebral small vessel disease (CSVD) is a well-known cause of vascular dementia, a leading medical morbidity in the aging population. Obstructive sleep apnea (OSA) has been validated as a cardiovascular risk factor. However, the relationship between these two clinical syndromes is not well established. We ai...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2019.11.1262
更新日期：2020-04-01 00:00:00
abstract：OBJECTIVE/BACKGROUND:Daytime napping longer than one hour has been associated with an increased risk for all-cause mortality. Associations between cytokine polymorphisms and daytime napping in chronic illnesses such as HIV, however, have not been well described. The purpose of this study was to examine cytokine polymor...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2016.12.021
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:It is now recognized that the vast majority of individuals with typical RBD will develop a synucleinopathy; usually 11-16 years after symptom onset. Parasomnia Overlap Disorder (POD) with adolescent-onset dream enactment behavior with phenoconversion to neurodegenerative disease after a long latency has not ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2019.01.041
更新日期：2019-05-01 00:00:00
abstract：:Rapid eye movement (REM) sleep behavior disorder (RBD) occurring prior to age 50 is termed early-onset RBD. Early-onset RBD comprises a substantial minority of cases, and demonstrates the differences in demographics, comorbidities, and clinical considerations from previously described typical RBD with onset >50years. ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2012.09.026
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND AND PURPOSE:This study explored the distribution of Epworth Sleepiness Scale (ESS) scores in a randomly sampled, community population and provided percentile scores that will assist in decision-making in both research and clinical settings. PATIENTS AND METHODS:Participants included 703 individuals between ...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2006.01.010
更新日期：2006-06-01 00:00:00
abstract：:A 63-year-old right-handed woman developed an alien hand syndrome (AHS) after an acute infarction in the territory of the left anterior cerebral artery. The uncontrolled hand movements were present during the daytime and eventually disturbed sleep. Polysomnography revealed that these motor actions only appeared when t...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/s1389-9457(02)00236-8
更新日期：2003-05-01 00:00:00
abstract：OBJECTIVE:As the relationships of sleep-wake schedule and mealtime with children's behaviors have not often been studied together, we investigated the relationships of these lifestyles variables with preschool children's well-being. METHODS:Using a network survey, we investigated several lifestyle variables of 1000 fa...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2019.03.023
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To create a sleep duration classification technique for waist-worn ActiGraph accelerometers in preschool-aged children. METHODS:Children wore ActiGraph wGT3X-BT accelerometers on their right hip for 7 days (24 h/day). Ground truth nap, sleep, and wake were estimated through visual inspection of accelerometer...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2020.12.019
更新日期：2021-01-08 00:00:00
abstract：PURPOSE:Obstructive sleep apnea (OSA) contributes to an increased risk for multiple co-morbidities and decreased quality of life. As a result, OSA patients may have higher usage of healthcare resources which can be mitigated with effective treatment. This study evaluates changes in healthcare utilization (HCU) followin...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2017.07.020
更新日期：2017-10-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy of moderate aerobic physical activity with sleep hygiene education to improve sleep, mood and quality of life in older adults with chronic insomnia. METHODS:Seventeen sedentary adults aged >or=55 years with insomnia (mean age 61.6 [SD±4.3] years; 16 female) participated in a randomized...
journal_title：Sleep medicine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.sleep.2010.04.014
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Intrinsic variance of the urine proteome limits the discriminative power of proteomic analysis and complicates potential biomarker detection in the context of paediatric sleep disorders. METHODS AND RESULTS:Using a rigorous workflow for proteomic analysis of urine, we demonstrate that gender and diurnal eff...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2014.01.010
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:Obstructive sleep apnea (OSA) and asthma are common and share similar nocturnal symptoms. We hypothesized that the prevalence of OSA symptoms would be greater in asthmatics compared to a general internal medicine population. METHODS:Patients in the Asthma Clinics (n=177) and Internal Medicine Clinics (n=328...
journal_title：Sleep medicine
pub_type： 杂志文章
doi：10.1016/j.sleep.2007.06.010
更新日期：2008-07-01 00:00:00
