Abstract:
:Lung cancer is one of the most common and deadly malignancies worldwide, in spite of advances in targeted therapy in recent years. An effective strategy for lung cancer prevention remains a major problem. Advances in next-generation sequencing have helped in understanding the RNA and identifying novel circular RNAs (circRNAs) that may have a broad impact on the early diagnosis and treatment of lung cancer. The circRNAs, exhibiting spatiotemporal-specific expression, are stable and conserved and present diverse biological functions in the normal and diseased states, including cancer. In this review, we summarize the recent advances in elucidating the functional role of circRNAs in lung cancer pathogenesis and discuss their potential mechanisms.
journal_name
Int J Biol Scijournal_title
International journal of biological sciencesauthors
Zhang C,Ma L,Niu Y,Wang Z,Xu X,Li Y,Yu Ydoi
10.7150/ijbs.39212subject
Has Abstractpub_date
2020-01-16 00:00:00pages
803-814issue
5issn
1449-2288pii
ijbsv16p0803journal_volume
16pub_type
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journal_title:International journal of biological sciences
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journal_title:International journal of biological sciences
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abstract::Non-coding RNAs (ncRNAs) are transcribed from genome but not translated into proteins. Many ncRNAs are key regulators of plants growth and development, metabolism and stress tolerance. In order to make the web-based ncRNA resources for plant science research be more easily accessible and understandable, we made a comp...
journal_title:International journal of biological sciences
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更新日期:2018-05-22 00:00:00
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journal_title:International journal of biological sciences
pub_type: 杂志文章,评审
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更新日期:2020-01-01 00:00:00
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更新日期:2009-10-28 00:00:00
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journal_title:International journal of biological sciences
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doi:10.7150/ijbs.40535
更新日期:2020-02-04 00:00:00
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journal_title:International journal of biological sciences
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doi:10.7150/ijbs.7242
更新日期:2013-11-05 00:00:00
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journal_title:International journal of biological sciences
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doi:10.7150/ijbs.5855
更新日期:2013-05-15 00:00:00
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journal_title:International journal of biological sciences
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更新日期:2005-01-01 00:00:00
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journal_title:International journal of biological sciences
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更新日期:2009-01-01 00:00:00
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更新日期:2020-03-15 00:00:00
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journal_title:International journal of biological sciences
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更新日期:2016-12-07 00:00:00