Phytochemical and comparative transcriptome analyses reveal different regulatory mechanisms in the terpenoid biosynthesis pathways between Matricaria recutita L. and Chamaemelum nobile L.

Abstract:

BACKGROUND:Matricaria recutita (German chamomile) and Chamaemelum nobile (Roman chamomile) belong to the botanical family Asteraceae. These two herbs are not only morphologically distinguishable, but their secondary metabolites - especially the essential oils present in flowers are also different, especially the terpenoids. The aim of this project was to preliminarily identify regulatory mechanisms in the terpenoid biosynthetic pathways that differ between German and Roman chamomile by performing comparative transcriptomic and metabolomic analyses. RESULTS:We determined the content of essential oils in disk florets and ray florets in these two chamomile species, and found that the terpenoid content in flowers of German chamomile is greater than that of Roman chamomile. In addition, a comparative RNA-seq analysis of German and Roman chamomile showed that 54% of genes shared > 75% sequence identity between the two species. In particular, more highly expressed DEGs (differentially expressed genes) and TF (transcription factor) genes, different regulation of CYPs (cytochrome P450 enzymes), and rapid evolution of downstream genes in the terpenoid biosynthetic pathway of German chamomile could be the main reasons to explain the differences in the types and levels of terpenoid compounds in these two species. In addition, a phylogenetic tree constructed from single copy genes showed that German chamomile and Roman chamomile are closely related to Chrysanthemum nankingense. CONCLUSION:This work provides the first insights into terpenoid biosynthesis in two species of chamomile. The candidate unigenes related to terpenoid biosynthesis will be important in molecular breeding approaches to modulate the essential oil composition of Matricaria recutita and Chamaemelum nobile.

journal_name

BMC Genomics

journal_title

BMC genomics

authors

Tai Y,Hou X,Liu C,Sun J,Guo C,Su L,Jiang W,Ling C,Wang C,Wang H,Pan G,Si X,Yuan Y

doi

10.1186/s12864-020-6579-z

subject

Has Abstract

pub_date

2020-02-18 00:00:00

pages

169

issue

1

issn

1471-2164

pii

10.1186/s12864-020-6579-z

journal_volume

21

pub_type

杂志文章
  • Haplotype analysis of sucrose synthase gene family in three Saccharum species.

    abstract:BACKGROUND:Sugarcane is an economically important crop contributing about 80% and 40% to the world sugar and ethanol production, respectively. The complicated genetics consequential to its complex polyploid genome, however, have impeded efforts to improve sugar yield and related important agronomic traits. Modern sugar...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-14-314

    authors: Zhang J,Arro J,Chen Y,Ming R

    更新日期:2013-05-10 00:00:00

  • In silico identification of genes involved in selenium metabolism: evidence for a third selenium utilization trait.

    abstract:BACKGROUND:Selenium (Se) is a trace element that occurs in proteins in the form of selenocysteine (Sec) and in tRNAs in the form of selenouridine (SeU). Selenophosphate synthetase (SelD) is required for both utilization traits. However, previous research also revealed SelDs in two organisms lacking Sec and SeU, suggest...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-9-251

    authors: Zhang Y,Turanov AA,Hatfield DL,Gladyshev VN

    更新日期:2008-05-29 00:00:00

  • Gill transcriptome response to changes in environmental calcium in the green spotted puffer fish.

    abstract:BACKGROUND:Calcium ion is tightly regulated in body fluids and for euryhaline fish, which are exposed to rapid changes in environmental [Ca2+], homeostasis is especially challenging. The gill is the main organ of active calcium uptake and therefore plays a crucial role in the maintenance of calcium ion homeostasis. To ...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-11-476

    authors: Pinto PI,Matsumura H,Thorne MA,Power DM,Terauchi R,Reinhardt R,Canário AV

    更新日期:2010-08-17 00:00:00

  • Discovering monotonic stemness marker genes from time-series stem cell microarray data.

    abstract:BACKGROUND:Identification of genes with ascending or descending monotonic expression patterns over time or stages of stem cells is an important issue in time-series microarray data analysis. We propose a method named Monotonic Feature Selector (MFSelector) based on a concept of total discriminating error (DEtotal) to i...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-16-S2-S2

    authors: Wang HW,Sun HJ,Chang TY,Lo HH,Cheng WC,Tseng GC,Lin CT,Chang SJ,Pal N,Chung IF

    更新日期:2015-01-01 00:00:00

  • Whole genome sequencing identified a 16 kilobase deletion on ECA13 associated with distichiasis in Friesian horses.

    abstract:BACKGROUND:Distichiasis, an ocular disorder in which aberrant cilia (eyelashes) grow from the opening of the Meibomian glands of the eyelid, has been reported in Friesian horses. These misplaced cilia can cause discomfort, chronic keratitis, and corneal ulceration, potentially impacting vision due to corneal fibrosis, ...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-020-07265-8

    authors: Hisey EA,Hermans H,Lounsberry ZT,Avila F,Grahn RA,Knickelbein KE,Duward-Akhurst SA,McCue ME,Kalbfleisch TS,Lassaline ME,Back W,Bellone RR

    更新日期:2020-11-30 00:00:00

  • Daily rhythmicity of clock gene transcript levels in fast and slow muscle fibers from Chinese perch (Siniperca chuatsi).

    abstract:BACKGROUND:Clock genes are considered to be the molecular core of biological clock in vertebrates and they are directly involved in the regulation of daily rhythms in vertebrate tissues such as skeletal muscles. Fish myotomes are composed of anatomically segregated fast and slow muscle fibers that possess different met...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-016-3373-z

    authors: Wu P,Li YL,Cheng J,Chen L,Zhu X,Feng ZG,Zhang JS,Chu WY

    更新日期:2016-12-08 00:00:00

  • Identification of candidate genes for human pituitary development by EST analysis.

    abstract:BACKGROUND:The pituitary is a critical neuroendocrine gland that is comprised of five hormone-secreting cell types, which develops in tandem during the embryonic stage. Some essential genes have been identified in the early stage of adenohypophysial development, such as PITX1, FGF8, BMP4 and SF-1. However, it is likely...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-10-109

    authors: Ma Y,Qi X,Du J,Song S,Feng D,Qi J,Zhu Z,Zhang X,Xiao H,Han Z,Hao X

    更新日期:2009-03-15 00:00:00

  • Genomic divergences among cattle, dog and human estimated from large-scale alignments of genomic sequences.

    abstract:BACKGROUND:Approximately 11 Mb of finished high quality genomic sequences were sampled from cattle, dog and human to estimate genomic divergences and their regional variation among these lineages. RESULTS:Optimal three-way multi-species global sequence alignments for 84 cattle clones or loci (each >50 kb of genomic se...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-7-140

    authors: Liu GE,Matukumalli LK,Sonstegard TS,Shade LL,Van Tassell CP

    更新日期:2006-06-07 00:00:00

  • The unique genomic landscape surrounding the EPSPS gene in glyphosate resistant Amaranthus palmeri: a repetitive path to resistance.

    abstract:BACKGROUND:The expanding number and global distributions of herbicide resistant weedy species threaten food, fuel, fiber and bioproduct sustainability and agroecosystem longevity. Amongst the most competitive weeds, Amaranthus palmeri S. Wats has rapidly evolved resistance to glyphosate primarily through massive amplif...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-016-3336-4

    authors: Molin WT,Wright AA,Lawton-Rauh A,Saski CA

    更新日期:2017-01-17 00:00:00

  • Genome-wide analysis of the WRKY gene family and their positive responses to phytoplasma invasion in Chinese jujube.

    abstract:BACKGROUND:The WRKY gene family is one of the most important families in higher plants. As transcription factors, they actively respond to biotic and abiotic stress and are also involved in plant development. Chinese jujube (Ziziphus jujuba Mill.) is the largest type of dried fruit tree in China in terms of production,...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-019-5789-8

    authors: Xue C,Li H,Liu Z,Wang L,Zhao Y,Wei X,Fang H,Liu M,Zhao J

    更新日期:2019-06-07 00:00:00

  • Functional innovations of three chronological mesohexaploid Brassica rapa genomes.

    abstract:BACKGROUND:The Brassicaceae family is an exemplary model for studying plant polyploidy. The Brassicaceae knowledge-base includes the well-annotated Arabidopsis thaliana reference sequence; well-established evidence for three rounds of whole genome duplication (WGD); and the conservation of genomic structure, with 24 co...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-15-606

    authors: Kim J,Lee J,Choi JP,Park I,Yang K,Kim MK,Lee YH,Nou IS,Kim DS,Min SR,Park SU,Kim H

    更新日期:2014-07-18 00:00:00

  • Transcriptome sequencing reveals genome-wide variation in molecular evolutionary rate among ferns.

    abstract:BACKGROUND:Transcriptomics in non-model plant systems has recently reached a point where the examination of nuclear genome-wide patterns in understudied groups is an achievable reality. This progress is especially notable in evolutionary studies of ferns, for which molecular resources to date have been derived primaril...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-016-3034-2

    authors: Grusz AL,Rothfels CJ,Schuettpelz E

    更新日期:2016-08-30 00:00:00

  • Strand-specific transcriptomes of Enterohemorrhagic Escherichia coli in response to interactions with ground beef microbiota: interactions between microorganisms in raw meat.

    abstract:BACKGROUND:Enterohemorrhagic Escherichia coli (EHEC) are zoonotic agents associated with outbreaks worldwide. Growth of EHEC strains in ground beef could be inhibited by background microbiota that is present initially at levels greater than that of the pathogen E. coli. However, how the microbiota outcompetes the patho...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-017-3957-2

    authors: Galia W,Leriche F,Cruveiller S,Garnier C,Navratil V,Dubost A,Blanquet-Diot S,Thevenot-Sergentet D

    更新日期:2017-08-03 00:00:00

  • Highly-multiplexed SNP genotyping for genetic mapping and germplasm diversity studies in pea.

    abstract:BACKGROUND:Single Nucleotide Polymorphisms (SNPs) can be used as genetic markers for applications such as genetic diversity studies or genetic mapping. New technologies now allow genotyping hundreds to thousands of SNPs in a single reaction.In order to evaluate the potential of these technologies in pea, we selected a ...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-11-468

    authors: Deulvot C,Charrel H,Marty A,Jacquin F,Donnadieu C,Lejeune-Hénaut I,Burstin J,Aubert G

    更新日期:2010-08-11 00:00:00

  • Identification of genomic aberrations in hemangioblastoma by droplet digital PCR and SNP microarray highlights novel candidate genes and pathways for pathogenesis.

    abstract:BACKGROUND:The genetic mechanisms underlying hemangioblastoma development are still largely unknown. We used high-resolution single nucleotide polymorphism microarrays and droplet digital PCR analysis to detect copy number variations (CNVs) in total of 45 hemangioblastoma tumors. RESULTS:We identified 94 CNVs with a m...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-016-2370-6

    authors: Mehrian-Shai R,Yalon M,Moshe I,Barshack I,Nass D,Jacob J,Dor C,Reichardt JK,Constantini S,Toren A

    更新日期:2016-01-14 00:00:00

  • Polysome profiling reveals broad translatome remodeling during endoplasmic reticulum (ER) stress in the pathogenic fungus Aspergillus fumigatus.

    abstract:BACKGROUND:The unfolded protein response (UPR) is a network of intracellular signaling pathways that supports the ability of the secretory pathway to maintain a balance between the load of proteins entering the endoplasmic reticulum (ER) and the protein folding capacity of the ER lumen. Current evidence indicates that ...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-15-159

    authors: Krishnan K,Ren Z,Losada L,Nierman WC,Lu LJ,Askew DS

    更新日期:2014-02-25 00:00:00

  • Discovery of cashmere goat (Capra hircus) microRNAs in skin and hair follicles by Solexa sequencing.

    abstract:BACKGROUND:MicroRNAs (miRNAs) are a large family of endogenous, non-coding RNAs, about 22 nucleotides long, which regulate gene expression through sequence-specific base pairing with target mRNAs. Extensive studies have shown that miRNA expression in the skin changes remarkably during distinct stages of the hair cycle ...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-14-511

    authors: Yuan C,Wang X,Geng R,He X,Qu L,Chen Y

    更新日期:2013-07-28 00:00:00

  • Genome-wide association and transcriptional studies reveal novel genes for unsaturated fatty acid synthesis in a panel of soybean accessions.

    abstract:BACKGROUND:The nutritional value of soybean oil is largely influenced by the proportions of unsaturated fatty acids (FAs), including oleic acid (OA, 18:1), linoleic acid (LLA, 18:2), and linolenic acid (LNA, 18:3). Genome-wide association (GWAS) studies along with gene expression studies in soybean [Glycine max (L.) Me...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-019-5449-z

    authors: Zhao X,Jiang H,Feng L,Qu Y,Teng W,Qiu L,Zheng H,Han Y,Li W

    更新日期:2019-01-21 00:00:00

  • Efficient depletion of ribosomal RNA for RNA sequencing in planarians.

    abstract:BACKGROUND:The astounding regenerative abilities of planarian flatworms prompt steadily growing interest in examining their molecular foundation. Planarian regeneration was found to require hundreds of genes and is hence a complex process. Thus, RNA interference followed by transcriptome-wide gene expression analysis b...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-019-6292-y

    authors: Kim IV,Ross EJ,Dietrich S,Döring K,Sánchez Alvarado A,Kuhn CD

    更新日期:2019-11-29 00:00:00

  • Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of heterozygosity is common in the cell lines but uncommon in primary tumors.

    abstract:BACKGROUND:Copy neutral loss of heterozygosity (CN-LOH) refers to a special case of LOH occurring without any resulting loss in copy number. These alterations is sometimes seen in tumors as a way to inactivate a tumor suppressor gene and have been found to be important in several types of cancer. RESULTS:We have used ...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-12-443

    authors: Kryh H,Carén H,Erichsen J,Sjöberg RM,Abrahamsson J,Kogner P,Martinsson T

    更新日期:2011-09-07 00:00:00

  • A comparative approach to elucidate chloroplast genome replication.

    abstract:BACKGROUND:Electron microscopy analyses of replicating chloroplast molecules earlier predicted bidirectional Cairns replication as the prevalent mechanism, perhaps followed by rounds of a rolling circle mechanism. This standard model is being challenged by the recent proposition of homologous recombination-mediated rep...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-10-237

    authors: Krishnan NM,Rao BJ

    更新日期:2009-05-20 00:00:00

  • Genome-wide association and prediction of direct genomic breeding values for composition of fatty acids in Angus beef cattle.

    abstract:BACKGROUND:As consumers continue to request food products that have health advantages, it will be important for the livestock industry to supply a product that meet these demands. One such nutrient is fatty acids, which have been implicated as playing a role in cardiovascular disease. Therefore, the objective of this s...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-14-730

    authors: Saatchi M,Garrick DJ,Tait RG Jr,Mayes MS,Drewnoski M,Schoonmaker J,Diaz C,Beitz DC,Reecy JM

    更新日期:2013-10-25 00:00:00

  • P_RNA_scaffolder: a fast and accurate genome scaffolder using paired-end RNA-sequencing reads.

    abstract:BACKGROUND:Obtaining complete gene structures is one major goal of genome assembly. Some gene regions are fragmented in low quality and high-quality assemblies. Therefore, new approaches are needed to recover gene regions. Genomes are widely transcribed, generating messenger and non-coding RNAs. These widespread transc...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-018-4567-3

    authors: Zhu BH,Xiao J,Xue W,Xu GC,Sun MY,Li JT

    更新日期:2018-03-02 00:00:00

  • RNAseq analysis of Aspergillus fumigatus in blood reveals a just wait and see resting stage behavior.

    abstract:BACKGROUND:Invasive aspergillosis is started after germination of Aspergillus fumigatus conidia that are inhaled by susceptible individuals. Fungal hyphae can grow in the lung through the epithelial tissue and disseminate hematogenously to invade into other organs. Low fungaemia indicates that fungal elements do not re...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-015-1853-1

    authors: Irmer H,Tarazona S,Sasse C,Olbermann P,Loeffler J,Krappmann S,Conesa A,Braus GH

    更新日期:2015-08-27 00:00:00

  • Mosquito transcriptome changes and filarial worm resistance in Armigeres subalbatus.

    abstract:BACKGROUND:Armigeres subalbatus is a natural vector of the filarial worm Brugia pahangi, but it rapidly and proficiently kills Brugia malayi microfilariae by melanotic encapsulation. Because B. malayi and B. pahangi are morphologically and biologically similar, the Armigeres-Brugia system serves as a valuable model for...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-8-463

    authors: Aliota MT,Fuchs JF,Mayhew GF,Chen CC,Christensen BM

    更新日期:2007-12-18 00:00:00

  • Reconstruction of evolutionary trajectories of chromosomes unraveled independent genomic repatterning between Triticeae and Brachypodium.

    abstract:BACKGROUND:After polyploidization, a genome may experience large-scale genome-repatterning, featuring wide-spread DNA rearrangement and loss, and often chromosome number reduction. Grasses share a common tetraploidization, after which the originally doubled chromosome numbers reduced to different chromosome numbers amo...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-019-5566-8

    authors: Wang Z,Wang J,Pan Y,Lei T,Ge W,Wang L,Zhang L,Li Y,Zhao K,Liu T,Song X,Zhang J,Yu J,Hu J,Wang X

    更新日期:2019-03-07 00:00:00

  • Expression dynamics and relations with nearby genes of rat transposable elements across 11 organs, 4 developmental stages and both sexes.

    abstract:BACKGROUND:TEs pervade mammalian genomes. However, compared with mice, fewer studies have focused on the TE expression patterns in rat, particularly the comparisons across different organs, developmental stages and sexes. In addition, TEs can influence the expression of nearby genes. The temporal and spatial influences...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-017-4078-7

    authors: Dong Y,Huang Z,Kuang Q,Wen Z,Liu Z,Li Y,Yang Y,Li M

    更新日期:2017-08-29 00:00:00

  • Complete plastid genome sequence of Daucus carota: implications for biotechnology and phylogeny of angiosperms.

    abstract:BACKGROUND:Carrot (Daucus carota) is a major food crop in the US and worldwide. Its capacity for storage and its lifecycle as a biennial make it an attractive species for the introduction of foreign genes, especially for oral delivery of vaccines and other therapeutic proteins. Until recently efforts to express recombi...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-7-222

    authors: Ruhlman T,Lee SB,Jansen RK,Hostetler JB,Tallon LJ,Town CD,Daniell H

    更新日期:2006-08-31 00:00:00

  • Uncovering molecular events associated with the chemosuppressive effects of flaxseed: a microarray analysis of the laying hen model of ovarian cancer.

    abstract:BACKGROUND:The laying hen model of spontaneous epithelial ovarian cancer (EOC) is unique in that it is the only model that enables observations of early events in disease progression and is therefore also uniquely suited for chemoprevention trials. Previous studies on the effect of dietary flaxseed in laying hens have ...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-15-709

    authors: Hales KH,Speckman SC,Kurrey NK,Hales DB

    更新日期:2014-08-24 00:00:00

  • Altering gene expression by aminocoumarins: the role of DNA supercoiling in Staphylococcus aureus.

    abstract:BACKGROUND:It has been shown previously that aminocoumarin antibiotics such as novobiocin lead to immediate downregulation of recA expression and thereby inhibit the SOS response, mutation frequency and recombination capacity in Staphylococcus aureus. Aminocoumarins function by inhibiting the ATPase activity of DNA gyr...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-15-291

    authors: Schröder W,Bernhardt J,Marincola G,Klein-Hitpass L,Herbig A,Krupp G,Nieselt K,Wolz C

    更新日期:2014-04-16 00:00:00