Abstract:
AIMS:Computational modelling may help us to detect the more important factors governing this process in order to optimize it. BACKGROUND:The generation of hazardous organic waste in teaching and research laboratories poses a big problem that universities have to manage. METHODS:In this work, we report on the experimental measurement of waste generation on the chemical education laboratories within our department. We measured the waste generated in the teaching laboratories of the Organic Chemistry Department II (UPV/EHU), in the second semester of the 2017/2018 academic year. Likewise, to know the anthropogenic and social factors related to the generation of waste, a questionnaire has been utilized. We focused on all students of Experimentation in Organic Chemistry (EOC) and Organic Chemistry II (OC2) subjects. It helped us to know their prior knowledge about waste, awareness of the problem of separate organic waste and the correct use of the containers. These results, together with the volumetric data, have been analyzed with statistical analysis software. We obtained two Perturbation-Theory Machine Learning (PTML) models including chemical, operational, and academic factors. The dataset analyzed included 6050 cases of laboratory practices vs. practices of reference. RESULTS:These models predict the values of acetone waste with R2 = 0.88 and non-halogenated waste with R2 = 0.91. CONCLUSION:This work opens a new gate to the implementation of more sustainable techniques and a circular economy with the aim of improving the quality of university education processes.
journal_name
Curr Top Med Chemjournal_title
Current topics in medicinal chemistryauthors
Montes-Bageneta I,Akesolo U,López S,Merino M,Anakabe E,Arrasate Sdoi
10.2174/1568026620666200211110043subject
Has Abstractpub_date
2020-01-01 00:00:00pages
720-730issue
9eissn
1568-0266issn
1873-4294pii
CTMC-EPUB-104382journal_volume
20pub_type
杂志文章abstract::The replication cycle of human immunodeficiency virus (HIV) is divided into an early and a late phase. Most of the steps of the cycle have been targeted in antiviral therapy, although the drugs currently available for clinical use are only effective against two replication enzymes of the virus, either against the reve...
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