Biomechanical evaluation of spinal fixation devices: I. A conceptual framework.


:In the field of spinal fixation devices, there is a profusion of new instrumentations. Often, the biomechanical evaluation is done in a nonstandardized manner, which makes it difficult to compare the results of one researcher with those of another, for the same device or for different devices. There is a need for a conceptual framework under which guidelines may be suggested for the evaluation of these devices in some uniform and comprehensive manner. There are three basic biomechanical tests: strength, fatigue, and stability. The strength test evaluates the failure load of the device, determines its weak points, and is helpful in the initial development of the device. The fatigue test provides a measure of longevity of the device, either alone or as part of the spinal construct, by testing the device to failure using cyclically varying loads. In contrast, the stability test measures the capability of the device to provide multi-directional stability to the injured spine. There is no failure of the device, and the results of this test are clinically important, as they characterize the potential for early fracture healing and early fusion. A conceptual framework for the evaluation of multi-direction stability of spinal fixation devices and guidelines for designing the necessary experiments are described.


Spine (Phila Pa 1976)




Panjabi MM




Has Abstract


1988-10-01 00:00:00














  • A prospective, randomized, controlled, multicenter study of osteogenic protein-1 in instrumented posterolateral fusions: report on safety and feasibility.

    abstract:STUDY DESIGN:A prospective, randomized, controlled, multicenter clinical study. OBJECTIVE:To evaluate the safety and feasibility of osteogenic protein (OP)-1 in 1-level lumbar spine instrumented posterolateral fusions. SUMMARY OF BACKGROUND DATA:Instrumented posterolateral fusion with the use of autograft is a common...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Delawi D,Dhert WJ,Rillardon L,Gay E,Prestamburgo D,Garcia-Fernandez C,Guerado E,Specchia N,Van Susante JL,Verschoor N,van Ufford HM,Oner FC

    更新日期:2010-05-20 00:00:00

  • Inpatient Pain Scores and Narcotic Utilization Based on American Society of Anesthesiologists Score Following Anterior Cervical Discectomy and Fusion.

    abstract:STUDY DESIGN:Retrospective. OBJECTIVE:To examine the relationship between American Society of Anesthesiologists (ASA) score and inpatient pain and narcotics consumption following anterior cervical discectomy and fusion (ACDF). SUMMARY OF BACKGROUND DATA:Higher ASA scores have been previously linked to increased posto...


    pub_type: 杂志文章


    authors: Yoo JS,Brundage TS,Hrynewycz NM,Singh K

    更新日期:2019-11-15 00:00:00

  • Feasibility and Accuracy of Thoracolumbar Minimally Invasive Pedicle Screw Placement With Augmented Reality Navigation Technology.

    abstract:STUDY DESIGN:Cadaveric laboratory study. OBJECTIVE:To assess the feasibility and accuracy of minimally invasive thoracolumbar pedicle screw placement using augmented reality (AR) surgical navigation. SUMMARY OF BACKGROUND DATA:Minimally invasive spine (MIS) surgery has increasingly become the method of choice for a w...


    pub_type: 杂志文章


    authors: Elmi-Terander A,Nachabe R,Skulason H,Pedersen K,Söderman M,Racadio J,Babic D,Gerdhem P,Edström E

    更新日期:2018-07-15 00:00:00

  • Age distribution of three radiologic factors for lumbar instability: probable aging process of the instability with disc degeneration.

    abstract:STUDY DESIGN:Cross-sectional study of 880 outpatients with low back and/or leg pain regarding age distribution of three radiologic factors. OBJECTIVES:To investigate the proportion and relationship of three individual radiologic factors with age on segmental instability in sagittal plane in consecutive age groups. SU...


    pub_type: 杂志文章


    authors: Iguchi T,Kanemura A,Kasahara K,Kurihara A,Doita M,Yoshiya S

    更新日期:2003-12-01 00:00:00

  • Surgical Consent of Children and Guardians for the Treatment of Adolescent Idiopathic Scoliosis is Incompletely Informed.

    abstract:STUDY DESIGN:Prospective, multicenter cohort analysis. OBJECTIVE:Assess children and guardian's comprehension of surgical consent for adolescent idiopathic scoliosis (AIS) surgery and factors associated with their comprehension. SUMMARY OF BACKGROUND DATA:Informed consent is essential to the ethical practice of surge...


    pub_type: 杂志文章,多中心研究


    authors: Theologis AA,Anaya A,Sabatini C,Sucato DJ,Parent S,Erickson M,Diab M

    更新日期:2016-01-01 00:00:00

  • Anterior interbody fusion of the cervical spine with coralline hydroxyapatite.

    abstract:STUDY DESIGN:A nonrandomized, retrospective human study of patients requiring anterior discectomy and reconstruction from C3 to T1. The pattern of incorporation, presence or absence of disc space collapse, maintenance of correction, and clinical outcomes were considered. OBJECTIVE:To determine the efficacy of corallin...


    pub_type: 杂志文章


    authors: Thalgott JS,Fritts K,Giuffre JM,Timlin M

    更新日期:1999-07-01 00:00:00

  • Surgical treatment of severe isthmic spondylolisthesis in adolescents. Reduction or fusion in situ.

    abstract::Twenty-two adolescent patients with severe (more than 50%) slip were surgically treated. Eleven were reduced with Magerl/Dick transpedicular screw devices and fused posteriorly from L4 to S1, and 2 weeks later anteriorly L5-S1; the other 11 were fused in situ L4-S1 (6 patients) or L5-S1 (5 patients) using a circumfere...


    pub_type: 杂志文章


    authors: Poussa M,Schlenzka D,Seitsalo S,Ylikoski M,Hurri H,Osterman K

    更新日期:1993-06-01 00:00:00

  • Use of video-assisted thoracoscopic surgery to reduce perioperative morbidity in scoliosis surgery.

    abstract:STUDY DESIGN:A case series of idiopathic scoliosis patients treated with thoracoscopic anterior instrumentation was compared to a similar group of patients treated by open anterior instrumentation. OBJECTIVES:To evaluate the morbidity associated with thoracoscopic instrumentation compared to the open approach for thor...


    pub_type: 杂志文章


    authors: Newton PO,Marks M,Faro F,Betz R,Clements D,Haher T,Lenke L,Lowe T,Merola A,Wenger D

    更新日期:2003-10-15 00:00:00

  • Comparison of Three Reconstructive Techniques in the Surgical Management of Patients With Four-Level Cervical Spondylotic Myelopathy.

    abstract:STUDY DESIGN:Retrospective clinical series. OBJECTIVE:To compare perioperative parameters, clinical outcomes, radiographic parameters, and complication rates of three reconstructive techniques after the anterior decompression of four-level cervical spondylotic myelopathy (CSM). SUMMARY OF BACKGROUND DATA:At present, ...


    pub_type: 杂志文章


    authors: Li Z,Wang H,Tang J,Ren D,Li L,Hou S,Zhang H,Hou T

    更新日期:2017-05-15 00:00:00

  • Automatic Cobb angle determination from radiographic images.

    abstract:STUDY DESIGN:Automatic measurement of Cobb angle in patients with scoliosis. OBJECTIVE:To test the accuracy of an automatic Cobb angle determination method from frontal radiographical images. SUMMARY OF BACKGROUND DATA:Thirty-six frontal radiographical images of patients with scoliosis. METHODS:A modified charged pa...


    pub_type: 杂志文章


    authors: Sardjono TA,Wilkinson MH,Veldhuizen AG,van Ooijen PM,Purnama KE,Verkerke GJ

    更新日期:2013-09-15 00:00:00

  • The relationship between the cross-sectional area of the cauda equina and the preoperative symptoms in central lumbar spinal stenosis.

    abstract:STUDY DESIGN:A cross-sectional registry and imaging cohort study. OBJECTIVES:To study the association between typical symptoms and signs of central spinal stenosis and the minimum cross-sectional area (mCSA) of the cauda equina in patients subsequently undergoing surgery. SUMMARY OF BACKGROUND DATA:Relations between ...


    pub_type: 杂志文章


    authors: Ogikubo O,Forsberg L,Hansson T

    更新日期:2007-06-01 00:00:00

  • Prospective comparative study of intradiscal high-dose and low-dose collagenase versus chymopapain.

    abstract::The mixed results of two studies on intradiscal therapy with collagenase versus chymopapain are presented. The first study was performed from January 1983 to March 1984 and consisted of 71 patients treated with collagenase injection (600 ABC units) and 93 patients treated with chymopapain injection (4,000 units) into ...


    pub_type: 杂志文章


    authors: Hedtmann A,Steffen R,Krämer J

    更新日期:1987-05-01 00:00:00

  • Analysis and prevention of spinal column deformity following cervical laminectomy. I. Pathogenetic analysis of postlaminectomy deformities.

    abstract::Postlaminectomy deformities were simulated in the cervical or cervicothoracic spine by the use of a displacement incremental method based on finite-element analysis combined with composite material and spanning element theory. The simulation analyses revealed that the primary cause of postlaminectomy deformity was the...


    pub_type: 杂志文章


    authors: Saito T,Yamamuro T,Shikata J,Oka M,Tsutsumi S

    更新日期:1991-05-01 00:00:00

  • Radicular pain after vertebroplasty: compression or irritation of the nerve root? Initial experience with the "cooling system".

    abstract:STUDY DESIGN:During vertebroplasty (VP), polymethylmethacrylate (PMMA) may leak into the posterior epidural venus plexus, provoking symptoms ranging from radicular pain to medullar compression. OBJECTIVES:To propose and test the feasibility of a procedure (cooling system) to prevent radicular irritation caused by fora...


    pub_type: 杂志文章


    authors: Kelekis AD,Martin JB,Somon T,Wetzel SG,Dietrich PY,Ruefenacht DA

    更新日期:2003-07-15 00:00:00

  • Respiratory dysfunction in patients with chronic-onset cervical myelopathy.

    abstract:STUDY DESIGN:A retrospective study. OBJECTIVE To clarify the characteristics of respiratory dysfunction associated with chronic-onset cervical myelopathy. SUMMARY OF BACKGROUND DATA:In acute cervical cord injury, respiratory dysfunction, especially vital capacity (VC), is impaired, which causes respiratory complicatio...


    pub_type: 杂志文章


    authors: Ishibe T,Takahashi S

    更新日期:2002-10-15 00:00:00

  • Effects of age and comorbidities on complication rates and adverse outcomes after lumbar laminectomy in elderly patients.

    abstract:STUDY DESIGN:This is a retrospective cohort study using the National Inpatient Sample database. OBJECTIVE:The objective is to report mortality and complications after lumbar laminectomy in the elderly. SUMMARY OF BACKGROUND DATA:As the population continues to age in the United States, it is important to consider the ...


    pub_type: 杂志文章


    authors: Li G,Patil CG,Lad SP,Ho C,Tian W,Boakye M

    更新日期:2008-05-15 00:00:00

  • Anterior cervical screw extrusion leading to acute upper airway obstruction: case report.

    abstract:STUDY DESIGN:Case report of late postoperative complication. SUMMARY OF BACKGROUND DATA:There have been a number of reports of migration and extrusion of cervical fusion instrumentation. The majority of such cases have a benign outcome. To our knowledge, cervical instrumentation extrusion resulting in prevertebral abs...


    pub_type: 杂志文章


    authors: Wong DT,Fehlings MG,Massicotte EM

    更新日期:2005-11-15 00:00:00

  • Changes in intervertebral disc cross-sectional area with bed rest and space flight.

    abstract:STUDY DESIGN:We measured the cross-sectional area of the intervertebral discs of normal volunteers after an overnight rest; before, during, and after 5 or 17 weeks of bed rest; and before and after 8 days of weightlessness. OBJECTIVES:This study sought to determine the degree of expansion of the lumbar discs resulting...


    pub_type: 杂志文章


    authors: LeBlanc AD,Evans HJ,Schneider VS,Wendt RE 3rd,Hedrick TD

    更新日期:1994-04-01 00:00:00

  • Painful osteolytic metastasis of the atlas: treatment with percutaneous vertebroplasty.

    abstract:STUDY DESIGN:Technical note. OBJECTIVE:To describe a technique for performing percutaneous vertebroplasty of C1 for treatment of osteolytic metastatic disease involving the lateral portions of the atlas in which precautions are taken to protect the vertebrobasilar arterial supply and a posterior access route is used f...


    pub_type: 杂志文章


    authors: Wetzel SG,Martin JB,Somon T,Wilhelm K,Rufenacht DA

    更新日期:2002-11-15 00:00:00

  • Quantitative Magnetization Transfer MRI Measurements of the Anterior Spinal Cord Region are Associated With Clinical Outcomes in Cervical Spondylotic Myelopathy.

    abstract:STUDY DESIGN:A case-control study. OBJECTIVE:The aim of this study was to understand the role of magnetization transfer ratio (MTR) in identifying patients with clinically significant myelopathy and disability. SUMMARY OF BACKGROUND DATA:MTR is a quantitative measure that correlates with myelin loss and neural tissue...


    pub_type: 杂志文章


    authors: Cloney MB,Smith ZA,Weber KA 2nd,Parrish TB

    更新日期:2018-05-15 00:00:00

  • Bilateral laminotomy and discectomy for segmental lumbar disc disease. Decompression with stability.

    abstract::A type of bilateral laminotomy with discectomy for segmental lumbar discogenic disease is presented. The procedure includes wide bilateral decompressive laminotomies and radical partial discectomies, partial V-ostectomy of the adjacent spinous processes, partial facetectomies of the inferior and superior articular pro...


    pub_type: 杂志文章


    authors: Herron LD,Pheasant HC

    更新日期:1983-01-01 00:00:00

  • Is sedation indicated before spinal injections?

    abstract:STUDY DESIGN:Survey. OBJECTIVE:The purpose of this research was to help determine whether sedation is indicated before lumbar and cervical interventional pain management procedures, and additionally, to determine whether benzodiazepams are effective at controlling anxiety for these procedures. SUMMARY OF BACKGROUND D...


    pub_type: 临床试验,杂志文章


    authors: Kim N,Delport E,Cucuzzella T,Marley J,Pruitt C

    更新日期:2007-12-01 00:00:00

  • Progressive scoliosis following chest wall resection in children.

    abstract::The effect of partial chest wall resection on subsequent production of spinal deformity was studied in six pediatric patients. The following observations are made: Scoliosis secondary to chest wall resection in the pediatric age group is progressive. The degree of curvature is related to the number of ribs resected. A...


    pub_type: 杂志文章


    authors: DeRosa GP

    更新日期:1985-09-01 00:00:00

  • Dual Time-Point 18F-FDG PET/CT in Spinal Sarcoidosis: A Single Institution Case Series.

    abstract:STUDY DESIGN:A case series of dual time-point F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (F-FDG PET/CT) for the diagnosis of spinal cord sarcoidosis. OBJECTIVE:The aim of this study was to illustrate three cases of spinal sarcoidosis with occult presentation and subsequent identificati...


    pub_type: 杂志文章


    authors: Ordóñez-Rubiano EG,Solano-Noguera DF,Row W,Weinberg J,Tatsui CE,Johnson JM,Gule-Monroe MK

    更新日期:2019-11-01 00:00:00

  • Acupuncture for chronic low back pain: a multicenter, randomized, patient-assessor blind, sham-controlled clinical trial.

    abstract:STUDY DESIGN:Multicenter, randomized, patient-assessor blind, sham-controlled clinical trial. OBJECTIVE:To investigate the efficacy of acupuncture treatment with individualized setting for reduction of bothersomeness in participants with chronic low back pain (cLBP). SUMMARY OF BACKGROUND DATA:Low back pain is one of...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Cho YJ,Song YK,Cha YY,Shin BC,Shin IH,Park HJ,Lee HS,Kim KW,Cho JH,Chung WS,Lee JH,Song MY

    更新日期:2013-04-01 00:00:00

  • Cross-Cultural Adaptation, Validity, and Reliability Study of the Turkish Version of Back Performance Scale.

    abstract:STUDY DESIGN:Validation of a performance scale. OBJECTIVE:The purpose of this study is to investigate adaptation, validity, and reliability of the Turkish version of the Back Performance Scale (BPS). SUMMARY OF BACKGROUND DATA:Low back pain affects people of all ages and causes pain, disability, and psychosocial prob...


    pub_type: 杂志文章


    authors: Maras G,Citaker S,Meray J

    更新日期:2019-01-01 00:00:00

  • Is There a Relationship Between Bony Fusion After Anterior Cervical Discectomy and Fusion and Heterotopic Ossification After Cervical Disc Arthroplasty in Hybrid Surgery?

    abstract:STUDY DESIGN:Retrospective analysis. OBJECTIVE:The aim of this study was to investigate the relationship between bony fusion after anterior cervical discectomy and fusion (ACDF) and heterotopic ossification (HO) after cervical disc arthroplasty (CDA) in hybrid surgery (HS). SUMMARY OF BACKGROUND DATA:The mechanism of...


    pub_type: 杂志文章


    authors: He J,Ding C,Liu H,Wu T,Huang K,Wang B,Hong Y,Liu Y

    更新日期:2020-12-15 00:00:00

  • The Minimum Clinically Important Difference for Patient Health Questionnaire-9 in Minimally Invasive Transforaminal Interbody Fusion.

    abstract:STUDY DESIGN:Retrospective Cohort OBJECTIVE.: Investigate and establish minimum clinically important differences (MCID) for PHQ-9 among patients undergoing minimally invasive transforaminal lumbar interbody fusion (MIS TLIF). SUMMARY OF BACKGROUND:Spine surgery is linked to postoperative improvements in anxiety, depre...


    pub_type: 杂志文章


    authors: Lynch CP,Cha EDK,Jenkins NW,Parrish JM,Mohan S,Jadczak CN,Geoghegan CE,Singh K

    更新日期:2020-12-07 00:00:00

  • Electronic monitoring improves brace-wearing compliance in patients with adolescent idiopathic scoliosis: a randomized clinical trial.

    abstract:STUDY DESIGN:Randomized controlled trial. OBJECTIVE:To assess whether monitoring increases brace-wearing compliance in patients with adolescent idiopathic scoliosis (AIS). SUMMARY OF BACKGROUND DATA:Noncompliance is a barrier to brace treatment of AIS. Studies have demonstrated that monitoring improves medication com...


    pub_type: 杂志文章,随机对照试验


    authors: Miller DJ,Franzone JM,Matsumoto H,Gomez JA,Avendaño J,Hyman JE,Roye DP Jr,Vitale MG

    更新日期:2012-04-20 00:00:00

  • Early reconstruction failures after multilevel cervical corpectomy.

    abstract:STUDY DESIGN:A retrospective analysis of graft and plate complications after multilevel anterior cervical corpectomy and fusion (ACF) attributed to spondylosis, stenosis, and ossification of posterior longitudinal ligament was conducted. OBJECTIVE:To identify factors contributing to graft and plate complications in th...


    pub_type: 杂志文章


    authors: Sasso RC,Ruggiero RA Jr,Reilly TM,Hall PV

    更新日期:2003-01-15 00:00:00