Abstract:
BACKGROUND:Measuring repolarization characteristics is challenging and has been reserved for experienced physicians. In electrocardiographic imaging (ECGI), activation-recovery interval (ARI) is used as a measure of local cardiac repolarization duration. We hypothesized that repolarization characteristics, such as local electrogram morphology and local and global dispersion of repolarization timing and duration could be of significance in ECGI. OBJECTIVE:To further explore their potential in arrhythmic risk stratification we investigated the use of novel repolarization parameters in ECGI. MATERIALS AND METHODS:We developed and compared methods for T-peak and T-end detection in reconstructed potentials. All methods were validated on annotated reconstructed electrograms (EGMs). Characteristics of the reconstructed EGMs and epicardial substrate maps in IVF patients were analyzed by using data recorded during sinus rhythm. The ECGI data were analyzed for EGM morphology, conduction, and repolarization. RESULTS:We acquired ECGI data from 8 subjects for this study. In all patients we evaluated four repolarization parameters: Repolarization time, T-wave area, Tpeak-Tend interval, and T-wave alternans. Most prominent findings were steep repolarization time gradients in regions with flat EGMs. These regions were also characterized by low T-wave area and large differences in Tpeak-Tend interval. CONCLUSIONS:Measuring novel repolarization parameters in reconstructed electrograms acquired with ECGI is feasible, can be done in a fully automated manner and may provide additional information on underlying arrhythmogenic substrate for risk stratification. Further studies are needed to investigate their potential use and clinical application.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Blom LJ,Groeneveld SA,Wulterkens BM,van Rees B,Nguyen UC,Roudijk RW,Cluitmans M,Volders PGA,Hassink RJdoi
10.1016/j.jelectrocard.2020.02.003subject
Has Abstractpub_date
2020-01-01 00:00:00pages
116-121eissn
0022-0736issn
1532-8430pii
S0022-0736(19)30902-1journal_volume
59pub_type
杂志文章abstract::Vagally mediated paroxysmal atrial fibrillation is typically described to occur in otherwise healthy young-to-middle aged males during periods of high vagal tone. We report a case of cardioinhibitory type neurocardiogenic syncope associated with atrial fibrillation in an elderly female during episodes of nausea. This ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2014.07.007
更新日期:2014-09-01 00:00:00
abstract::Many electrocardiographic criteria have been proposed for the differentiation of ventricular extrasystole and supraventricular conduction with aberrancy in atrial fibrillation but the validity of these have not been confirmed by intracardiac studies. We recorded His bundle electrograms in nineteen patients (eleven men...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(85)80033-9
更新日期:1985-01-01 00:00:00
abstract::Information from 24-hour monitoring with on-line vectorcardiography, starting immediately after admission, was compared with results from a predischarge exercise test 3-13 days after admission. A total of 169 patients with acute myocardial infarction and 73 patients with unstable angina pectoris were investigated. Pat...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
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更新日期:1995-10-01 00:00:00
abstract:PURPOSE:Recent research has established that a tall R-wave in V1 indicates lateral wall involvement in non-anterior wall myocardial infarction (MI). The objective of this study was to assess the value of the admission electrocardiogram (ECG) to predict R-waves and consequently lateral wall damage in the late phase of n...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2015.02.005
更新日期:2015-07-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(85)80029-7
更新日期:1985-01-01 00:00:00
abstract::The present study was performed to evaluate the specificity of twin peaked P wave (TWPP) for left atrial overload (LOA) in orthogonal ECGs. A total of 2093 ECGs recorded with Frank's corrected orthogonal leads were used for analysis. It can be concluded from the present study that (1) TWPP is diagnostically non-specif...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(80)80051-3
更新日期:1980-04-01 00:00:00
abstract::Atrioventricular node reentry tachycardia is an incompletely understood substrate for supraventricular tachycardia. Although there is agreement that the mechanism involves functionally separate fast and slow AV node pathways, which are somewhat anatomically discrete, the anatomical basis for the reentrant circuit is n...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jelectrocard.2008.06.016
更新日期:2008-11-01 00:00:00
abstract::A three-dimensional heart model was constructed to simulate late potentials and ventricular fibrillation (VF). The model consisted of 50,000 discrete elements having a 1.5-mm spatial resolution. Each element represented excitable ventricular tissue, including a conduction system, and was characterized with classical f...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract::Sudden cardiac death occurs as a result of a complex interplay of changes in myocardial substrate, imbalance of autonomic regulation of the heart, and myocardial vulnerability. Noninvasive electrocardiology serves as a comprehensive tool for investigating factors representing mechanistic pathways leading to cardiac ev...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jelectrocard.2003.09.022
更新日期:2003-01-01 00:00:00
abstract::Ventricular fibrillation (VF) is the most common arrhythmia leading to sudden cardiac death, but in rare cases VF can manifest as a syncope, provided that it will self-terminate. We present a case of a 45-year old female with a history of unexplained syncopal episodes despite exhaustive diagnostics. Implantable loop r...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2018.04.006
更新日期:2018-01-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2019.11.043
更新日期:2020-01-01 00:00:00
abstract::Left ventricular (LV) dysfunction after myocardial infarction is associated with higher risk of serious ventricular arrhythmias and sudden death. We suspected that heterogeneity in ventricular repolarization contributes to these arrhythmias. To quantify this heterogeneity, we measured the recovery time (the interval b...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1054/jelc.2003.50005
更新日期:2003-01-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2012.05.001
更新日期:2012-09-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(10)80019-6
更新日期:1992-01-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(79)80060-6
更新日期:1979-07-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(85)80024-8
更新日期:1985-10-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2010.06.007
更新日期:2010-11-01 00:00:00
abstract::The dominant T wave (DTW) reflects the derivative of the repolarization phase of the transmembrane potential of myocytes. T-wave alternans (TWA) is defined as an alteration of this repolarization that repeats every other beat. We investigate if the DTW can offer new insight on TWA. We first proved that the DTW estimat...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2010.11.017
更新日期:2011-03-01 00:00:00
abstract::Patients with paroxysmal atrial fibrillation (AF) have greater overall P wave magnitude than control subjects, but the temporal localization of the increased energy is unknown. P wave spectral turbulence has not been investigated in such patients, and the optimum methodology for studying P wave signals has not been de...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(97)80013-1
更新日期:1997-04-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2007.05.016
更新日期:2007-11-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2017.02.012
更新日期:2017-01-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.jelectrocard.2004.01.003
更新日期:2004-04-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1054/jelc.2002.35844
更新日期:2002-10-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(98)90308-9
更新日期:1998-01-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(88)90105-7
更新日期:1988-11-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1054/jelc.2002.29943
更新日期:2002-01-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2015.08.006
更新日期:2016-01-01 00:00:00
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journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(96)80124-5
更新日期:1996-04-01 00:00:00
abstract::Hidden Markov modelling (HMM) is a powerful stochastic modelling technique that has been successfully applied to automatic speech recognition problems. We are currently investigating the application of HMM to electrocardiographic signal analysis with the goal of improving ambulatory ECG analysis. The HMM approach spec...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(90)90099-n
更新日期:1990-01-01 00:00:00