Oxathiapiprolin, a Novel Chemical Inducer Activates the Plant Disease Resistance.

Abstract:

:Oxathiapiprolin was developed as a specific plant pathogenic oomycete inhibitor, previously shown to have highly curative and protective activities against the pepper Phytophthora blight disease under field and greenhouse tests. Therefore, it was hypothesized that oxathiapiprolin might potentially activate the plant disease resistance against pathogen infections. This study investigated the potential and related mechanism of oxathiapiprolin to activate the plant disease resistance using the bacterium Pseudomonas syringae pv tomato (Pst) and plant Arabidopsis interaction as the targeted system. Our results showed that oxathiapiprolin could activate the plant disease resistance against Pst DC3000, a non-target pathogen of oxathiapiprolin, in Arabidopsis, tobacco, and tomato plants. Our results also showed the enhanced callose deposition and H2O2 accumulation in the oxathiapiprolin-treated Arabidopsis under the induction of flg22 as the pathogen-associated molecular pattern (PAMP) treatment. Furthermore, increased levels of free salicylic acid (SA) and jasmonic acid (JA) were detected in the oxathiapiprolin-treated Arabidopsis plants compared to the mock-treated ones under the challenge of Pst DC3000. Besides, the gene expression results confirmed that at 24 h after the infiltration with Pst DC3000, the oxathiapiprolin-treated Arabidopsis plants had upregulated expression levels of the respiratory burst oxidase homolog D (RBOHD), JA-responsive gene (PDF1.2), and SA-responsive genes (PR1, PR2, and PR5) compared to the control. Taken together, oxathiapiprolin is identified as a novel chemical inducer which activates the plant disease resistance against Pst DC3000 by enhancing the callose deposition, H2O2 accumulation, and hormone SA and JA production.

journal_name

Int J Mol Sci

authors

Peng Q,Wang Z,Liu P,Liang Y,Zhao Z,Li W,Liu X,Xia Y

doi

10.3390/ijms21041223

subject

Has Abstract

pub_date

2020-02-12 00:00:00

issue

4

issn

1422-0067

pii

ijms21041223

journal_volume

21

pub_type

杂志文章
  • Hydroxyl Radical-Suppressing Mechanism and Efficiency of Melanin-Mimetic Nanoparticles.

    abstract::Harnessing melanins to scavenge free radicals in vivo may yield treatment methods for inflammatory disorders. Furthermore, elucidation of the mechanism underlying melanin-mediated suppression of free radicals, which is yet unclear, is warranted. Herein, we chemically synthesized melanin-mimetic nanoparticles (MeNPs) a...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19082309

    authors: Hayashi K,Tokuda A,Sakamoto W

    更新日期:2018-08-07 00:00:00

  • In vitro models in biocompatibility assessment for biomedical-grade chitosan derivatives in wound management.

    abstract::One of the ultimate goals of wound healing research is to find effective healing techniques that utilize the regeneration of similar tissues. This involves the modification of various wound dressing biomaterials for proper wound management. The biopolymer chitosan (beta-1,4-D-glucosamine) has natural biocompatibility ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms10031300

    authors: Keong LC,Halim AS

    更新日期:2009-03-01 00:00:00

  • Perillyl Alcohol and Its Drug-Conjugated Derivatives as Potential Novel Methods of Treating Brain Metastases.

    abstract::Metastasis to the central nervous system remains difficult to treat, and such patients are faced with a dismal prognosis. The blood-brain barrier (BBB), despite being partially compromised within malignant lesions in the brain, still retains much of its barrier function and prevents most chemotherapeutic agents from e...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms17091463

    authors: Chen TC,Da Fonseca CO,Schönthal AH

    更新日期:2016-09-02 00:00:00

  • A Tale of Two Proteolytic Machines: Matrix Metalloproteinases and the Ubiquitin-Proteasome System in Pulmonary Fibrosis.

    abstract::Pulmonary fibrosis is a chronic and progressive lung disease characterized by the activation of fibroblasts and the irreversible deposition of connective tissue matrices that leads to altered pulmonary architecture and physiology. Multiple factors have been implicated in the pathogenesis of lung fibrosis, including ge...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms21113878

    authors: Roque W,Boni A,Martinez-Manzano J,Romero F

    更新日期:2020-05-29 00:00:00

  • Dissemination of Genetic Acquisition/Loss Provides a Variety of Quorum Sensing Regulatory Properties in Pseudoalteromonas.

    abstract::A bstract: Quorum sensing (QS) enables single-celled bacteria to communicate with chemical signals in order to synchronize group-level bacterial behavior. Pseudoalteromonas are marine bacteria found in versatile environments, of which QS regulation for their habitat adaptation is extremely fragmentary. To distinguish ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19113636

    authors: Yu Z,Ding Y,Yin J,Yu D,Zhang J,Zhang M,Ding M,Zhong W,Qiu J,Li J

    更新日期:2018-11-18 00:00:00

  • MOS1 Negatively Regulates Sugar Responses and Anthocyanin Biosynthesis in Arabidopsis.

    abstract::Sugars, which are important signaling molecules, regulate diverse biological processes in plants. However, the convergent regulatory mechanisms governing these physiological activities have not been fully elucidated. MODIFIER OF snc1-1 (MOS1), a modulator of plant immunity, also regulates floral transition, cell cycle...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21197095

    authors: Zhang N,Wang M,Huang J,Yang L,Wang Z,Wu D,Shu X

    更新日期:2020-09-26 00:00:00

  • Deep Sequencing and Screening of Differentially Expressed MicroRNAs Related to Milk Fat Metabolism in Bovine Primary Mammary Epithelial Cells.

    abstract::Milk fat is a key factor affecting milk quality and is also a major trait targeted in dairy cow breeding. To determine how the synthesis and the metabolism of lipids in bovine milk is regulated at the miRNA level, primary mammary epithelial cells (pMEC) derived from two Chinese Holstein dairy cows that produced extrem...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms17020200

    authors: Shen B,Zhang L,Lian C,Lu C,Zhang Y,Pan Q,Yang R,Zhao Z

    更新日期:2016-02-17 00:00:00

  • Assessment of Dextran Antigenicity of Intravenous Iron Preparations with Enzyme-Linked Immunosorbent Assay (ELISA).

    abstract::Intravenous iron preparations are typically classified as non-dextran-based or dextran/dextran-based complexes. The carbohydrate shell for each of these preparations is unique and is key in determining the various physicochemical properties, the metabolic pathway, and the immunogenicity of the iron-carbohydrate comple...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms17071185

    authors: Neiser S,Koskenkorva TS,Schwarz K,Wilhelm M,Burckhardt S

    更新日期:2016-07-21 00:00:00

  • Terminal Phase Components of the Clotting Cascade in Patients with End-Stage Renal Disease Undergoing Hemodiafiltration or Hemodialysis Treatment.

    abstract::Hemostasis disorder in patients with end-stage renal disease (ESRD) is frequently associated with bleeding diathesis but it may also manifest in thrombotic complications. Analysis of individual coagulation and fibrinolytic factors may shed light on the background of this paradox situation. Here we explored components ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21228426

    authors: Pénzes K,Hurják B,Katona É,Becs G,Balla J,Muszbek L

    更新日期:2020-11-10 00:00:00

  • Reduced Diet-induced Thermogenesis in Apolipoprotein A-IV Deficient Mice.

    abstract::In the presence of dietary lipids, both apolipoprotein A-IV (ApoA-IV) production and brown adipose tissue (BAT) thermogenesis are increased. The effect of dietary lipid-induced AproA-IV on BAT thermogenesis and energy expenditure remains unknown. In the present study, we hypothesized that ApoA-IV knockout (ApoA-IV-KO)...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20133176

    authors: Pence S,Zhu Q,Binne E,Liu M,Shi H,Lo CC

    更新日期:2019-06-28 00:00:00

  • Application of ionic liquids in high performance reversed-phase chromatography.

    abstract::Ionic liquids, considered "green" chemicals, are widely used in many areas of analytical chemistry due to their unique properties. Recently, ionic liquids have been used as a kind of novel additive in separation and combined with silica to synthesize new stationary phase as separation media. This review will focus on ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms10062591

    authors: Wang Y,Tian M,Bi W,Row KH

    更新日期:2009-06-04 00:00:00

  • Pro-Resolving Molecules-New Approaches to Treat Sepsis?

    abstract::Inflammation is a complex response of the body to exogenous and endogenous insults. Chronic and systemic diseases are attributed to uncontrolled inflammation. Molecules involved in the initiation of inflammation are very well studied while pathways regulating its resolution are insufficiently investigated. Approaches ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms18030476

    authors: Buechler C,Pohl R,Aslanidis C

    更新日期:2017-02-23 00:00:00

  • Molecular Research on Emerging Viruses: Evolution, Diagnostics, Pathogenesis, and Therapeutics.

    abstract::Viruses are increasingly recognized as emerging infectious disease agents in both humans and animals.[...]. ...

    journal_title:International journal of molecular sciences

    pub_type: 社论

    doi:10.3390/ijms19020398

    authors: Lau SKP

    更新日期:2018-01-30 00:00:00

  • TMPRSS4 as a poor prognostic factor for triple-negative breast cancer.

    abstract::Triple-negative breast cancer (TNBC) is characterized by the lack of immunohistochemical staining for estrogen receptors (ER), progesterone receptors (PR), and lack of overexpression or amplification of human epidermal growth factor receptor 2 (HER2). Our aim was to investigate the expression of transmembrane protease...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms140714659

    authors: Cheng D,Kong H,Li Y

    更新日期:2013-07-12 00:00:00

  • Atrazine affects phosphoprotein and protein expression in MCF-10A human breast epithelial cells.

    abstract::Atrazine, a member of the 2-chloro-s-triazine family of herbicides, is the most widely used pesticide in the world and often detected in agriculture watersheds. Although it was generally considered as an endocrine disruptor, posing a potential threat to human health, the molecular mechanisms of atrazine effects remain...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms151017806

    authors: Huang P,Yang J,Song Q

    更新日期:2014-10-01 00:00:00

  • Structural Insights into tRNA Dynamics on the Ribosome.

    abstract::High-resolution structures at different stages, as well as biochemical, single molecule and computational approaches have highlighted the elasticity of tRNA molecules when bound to the ribosome. It is well acknowledged that the inherent structural flexibility of the tRNA lies at the heart of the protein synthesis proc...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms16059866

    authors: Agirrezabala X,Valle M

    更新日期:2015-04-30 00:00:00

  • Causal Transcription Regulatory Network Inference Using Enhancer Activity as a Causal Anchor.

    abstract::Transcription control plays a crucial role in establishing a unique gene expression signature for each of the hundreds of mammalian cell types. Though gene expression data have been widely used to infer cellular regulatory networks, existing methods mainly infer correlations rather than causality. We developed statist...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19113609

    authors: Vipin D,Wang L,Devailly G,Michoel T,Joshi A

    更新日期:2018-11-15 00:00:00

  • Prediction of a new ligand-binding site for type 2 motif based on the crystal structure of ALG-2 by dry and wet approaches.

    abstract::ALG-2 is a penta-EF-hand Ca(2+)-binding protein and interacts with a variety of intracellular proteins. Two types of ALG-2-binding motifs have been determined: type 1, PXYPXnYP (X, variable; n = 4), in ALIX and PLSCR3; type 2, PXPGF, in Sec31A and PLSCR3. The previously solved X-ray crystal structure of the complex be...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms13067532

    authors: Takahashi T,Suzuki H,Inuzuka T,Shibata H,Maki M

    更新日期:2012-01-01 00:00:00

  • Gomisin N from Schisandra chinensis Ameliorates Lipid Accumulation and Induces a Brown Fat-Like Phenotype through AMP-Activated Protein Kinase in 3T3-L1 Adipocytes.

    abstract::Obesity results from an imbalance between energy intake and energy expenditure, in which excess fat is stored as triglycerides (TGs) in white adipocytes. Recent studies have explored the anti-obesity effects of certain edible phytochemicals, which suppress TG accumulation and stimulate a brown adipocyte-like phenotype...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21062153

    authors: Lee K,Lee YJ,Kim KJ,Chei S,Jin H,Oh HJ,Lee BY

    更新日期:2020-03-20 00:00:00

  • A Novel Zinc Chelator, 1H10, Ameliorates Experimental Autoimmune Encephalomyelitis by Modulating Zinc Toxicity and AMPK Activation.

    abstract::Previous studies in our lab revealed that chemical zinc chelation or zinc transporter 3 (ZnT3) gene deletion suppresses the clinical features and neuropathological changes associated with experimental autoimmune encephalomyelitis (EAE). In addition, although protective functions are well documented for AMP-activated p...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21093375

    authors: Choi BY,Jeong JH,Eom JW,Koh JY,Kim YH,Suh SW

    更新日期:2020-05-10 00:00:00

  • TFIP11 interacts with mDEAH9, an RNA helicase involved in spliceosome disassembly.

    abstract::Yeast proteins Ntr1, Ntr2 and Prp43 function in spliceosome disassembly. An Ntr1-Ntr2 protein complex recruits Prp43 to allow the removal of the lariat-intron in late-stage RNA splicing activity. Based on amino-acid sequence similarities across species, TFIP11 and mDEAH9/Dhx15 have been identified as homologues of yea...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms9112105

    authors: Wen X,Tannukit S,Paine ML

    更新日期:2008-11-01 00:00:00

  • Key Developments in Ionic Liquid Crystals.

    abstract::Ionic liquid crystals are materials that combine the classes of liquid crystals and ionic liquids. The first one is based on the multi-billion-dollar flat panel display industry, whilst the latter quickly developed in the past decades into a family of highly-tunable non-volatile solvents. The combination yields materi...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms17050731

    authors: Alvarez Fernandez A,Kouwer PH

    更新日期:2016-05-16 00:00:00

  • Optimizing PCR Detection of West Nile Virus from Body Fluid Specimens to Delineate Natural History in an Infected Human Cohort.

    abstract::West Nile virus (WNV), a mosquito-borne arbovirus, remains a major global health concern. In this study, we optimized PCR methods then assessed serially-collected whole blood (WB), urine (UR), saliva, and semen specimens from a large cohort of WNV-positive participants to evaluate the natural history of infection and ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20081934

    authors: Gorchakov R,Gulas-Wroblewski BE,Ronca SE,Ruff JC,Nolan MS,Berry R,Alvarado RE,Gunter SM,Murray KO

    更新日期:2019-04-19 00:00:00

  • Impact and Intricacies of Bone Marrow Microenvironment in B-cell Lymphomas: From Biology to Therapy.

    abstract::Lymphoma, a group of widely prevalent hematological malignancies of lymphocyte origin, has become the focus of significant clinical research due to their high propensity for refractory/relapsed (R/R) disease, leading to poor prognostic outcomes. The complex molecular circuitry in lymphomas, especially in the aggressiv...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms21030904

    authors: Sircar A,Chowdhury SM,Hart A,Bell WC,Singh S,Sehgal L,Epperla N

    更新日期:2020-01-30 00:00:00

  • Salicylic Acid Induces Resistance in Rubber Tree against Phytophthora palmivora.

    abstract::Induced resistance by elicitors is considered to be an eco-friendly strategy to stimulate plant defense against pathogen attack. In this study, we elucidated the effect of salicylic acid (SA) on induced resistance in rubber tree against Phytophthora palmivora and evaluated the possible defense mechanisms that were inv...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19071883

    authors: Deenamo N,Kuyyogsuy A,Khompatara K,Chanwun T,Ekchaweng K,Churngchow N

    更新日期:2018-06-26 00:00:00

  • Regulation of enzyme activity through interactions with nanoparticles.

    abstract::The structure and function of an enzyme can be altered by nanoparticles (NPs). The interaction between enzyme and NPs is governed by the key properties of NPs, such as structure, size, surface chemistry, charge and surface shape. Recent representative studies on the NP-enzyme interactions and the regulation of enzyme ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms10104198

    authors: Wu Z,Zhang B,Yan B

    更新日期:2009-11-20 00:00:00

  • Metabolomics and Transcriptomics Identify Multiple Downstream Targets of Paraburkholderia phymatum σ54 During Symbiosis with Phaseolus vulgaris.

    abstract::RpoN (or σ54) is the key sigma factor for the regulation of transcription of nitrogen fixation genes in diazotrophic bacteria, which include α- and β-rhizobia. Our previous studies showed that an rpoN mutant of the β-rhizobial strain Paraburkholderia phymatum STM815T formed root nodules on Phaseolus vulgaris cv. Negro...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19041049

    authors: Lardi M,Liu Y,Giudice G,Ahrens CH,Zamboni N,Pessi G

    更新日期:2018-04-01 00:00:00

  • Atomic Force Microscopy Based Tip-Enhanced Raman Spectroscopy in Biology.

    abstract::Most biological phenomena occur at the nanometer scale, which is not accessible by the conventional optical techniques because of the optical diffraction limitation. Tip-enhanced Raman spectroscopy (TERS), one of the burgeoning probing techniques, not only can provide the topography characterization with high resoluti...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms19041193

    authors: Gao L,Zhao H,Li T,Huo P,Chen D,Liu B

    更新日期:2018-04-13 00:00:00

  • An Integrated Approach of Proteomics and Computational Genetic Modification Effectiveness Analysis to Uncover the Mechanisms of Flood Tolerance in Soybeans.

    abstract::Flooding negatively affects the growth of soybeans. Recently, omic approaches have been used to study abiotic stress responses in plants. To explore flood-tolerant genes in soybeans, an integrated approach of proteomics and computational genetic modification effectiveness analysis was applied to the soybean (Glycine m...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19051301

    authors: Wang X,Sakata K,Komatsu S

    更新日期:2018-04-26 00:00:00

  • Impact of Chronic Hepatitis C Virus Genotype 1b Infection on Triglyceride Concentration in Serum Lipoprotein Fractions.

    abstract::Reduced low-density lipoprotein (LDL) cholesterol level is a characteristic feature of dyslipidemia in chronic hepatitis C virus (HCV) infection. However, abnormality in serum triglyceride (TG) has not been fully investigated. To clarify the impact of HCV genotype 1b (G1b) infection and advanced fibrosis on serum TG p...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms160920576

    authors: Nagano T,Seki N,Tomita Y,Sugita T,Aida Y,Itagaki M,Sutoh S,Abe H,Tsubota A,Aizawa Y

    更新日期:2015-08-31 00:00:00