Tension-type headache in the Emergency Department Diagnosis and misdiagnosis: The TEDDi study.

Abstract:

:Headache is a common reason to visit the emergency department (ED). Tension-type headache (TTH) is the commonest headache. The diagnosis of TTH implies a mild condition, with no need for special tests. We evaluated the use of the International Classification of Headache Disorders (ICHD) criteria for TTH in the ED. We performed a cross-sectional study including all ED patients with a definite TTH diagnosis in their discharge report for 2.5 years. We evaluated whether the ICHD criteria for TTH were referenced and met. We analysed discrepancies concerning anamnesis or prior history and reclassified patients. A total of 211 out of 2132 patients fulfilled the criteria (9.9%). Only five patients fulfilled TTH criteria. Criteria A-D were referenced in 60-84% of patients and met in 16-74% of these patients. Anamnesis was discrepant in 87.5% as was prior history in 20.8%. After re-reclassification, 21 patients fulfilled the criteria for TTH (five) or probable TTH (16). In 106 patients, another headache was diagnosed, with migraine in 40 (18.9%), secondary headache in 64 (30.3%), and a life-threatening disorder in 13 (6.1%). In our sample, TTH was overdiagnosed. Only a minority of patients fulfilled the ICHD criteria. Inconsistencies in prior medical history or anamnesis were frequent.

journal_name

Sci Rep

journal_title

Scientific reports

authors

García-Azorín D,Farid-Zahran M,Gutiérrez-Sánchez M,González-García MN,Guerrero AL,Porta-Etessam J

doi

10.1038/s41598-020-59171-4

subject

Has Abstract

pub_date

2020-02-12 00:00:00

pages

2446

issue

1

issn

2045-2322

pii

10.1038/s41598-020-59171-4

journal_volume

10

pub_type

杂志文章
  • Tosylation of alcohols: an effective strategy for the functional group transformation of organic derivatives of polyoxometalates.

    abstract::Recently, the organic functionalization of polyoxometalates (POMs) has drawn increasing interest, and an easy and effective route to achieve organic derivatives is of great importance. Herein, the first reported synthesis of a tosyl ester derivative of the polyoxometalate (Bu4N)2[V6O13{(OCH2)3CCH2SO3C7H4}2]·2.5CH3CN (...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-12633-8

    authors: Jia H,Li Q,Bayaguud A,She S,Huang Y,Chen K,Wei Y

    更新日期:2017-10-02 00:00:00

  • Efficient derivation of knock-out and knock-in rats using embryos obtained by in vitro fertilization.

    abstract::Rats are effective model animals and have contributed to the development of human medicine and basic research. However, the application of reproductive engineering techniques to rats is not as advanced compared with mice, and genome editing in rats has not been achieved using embryos obtained by in vitro fertilization...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-47964-1

    authors: Honda A,Tachibana R,Hamada K,Morita K,Mizuno N,Morita K,Asano M

    更新日期:2019-08-09 00:00:00

  • Angiotensin II synergizes with BAFF to promote atheroprotective regulatory B cells.

    abstract::Angiotensin II (AngII) promotes hypertension, atherogenesis, vascular aneurysm and impairs post-ischemic cardiac remodeling through concerted roles on vascular cells, monocytes and T lymphocytes. However, the role of AngII in B lymphocyte responses is largely unexplored. Here, we show that chronic B cell depletion (Ba...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-04438-6

    authors: Ponnuswamy P,Joffre J,Herbin O,Esposito B,Laurans L,Binder CJ,Tedder TF,Zeboudj L,Loyer X,Giraud A,Zhang Y,Tedgui A,Mallat Z,Ait-Oufella H

    更新日期:2017-06-23 00:00:00

  • How goats avoid ingesting noxious insects while feeding.

    abstract::As mammalian herbivores feed, they often encounter noxious insects on plants. It is unknown how they handle such insects. We experimentally examined the behavioural responses of goats to the noxious spring-webworm (Ocnogyna loewii), and manipulated their sensory perception to reveal the process of insect detection. Go...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-14940-6

    authors: Berman TS,Ben-Ari M,Glasser TA,Gish M,Inbar M

    更新日期:2017-11-01 00:00:00

  • DNA methylation regulates TMEM16A/ANO1 expression through multiple CpG islands in head and neck squamous cell carcinoma.

    abstract::ANO1 is a calcium-activated chloride channel that is frequently overexpressed in head and neck squamous cell carcinoma (HNSCC) and other cancers. While ANO1 expression negatively correlates with survival in several cancers, its epigenetic regulation is poorly understood. We analyzed HNSCC samples from TCGA and a separ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-15634-9

    authors: Finegersh A,Kulich S,Guo T,Favorov AV,Fertig EJ,Danilova LV,Gaykalova DA,Califano JA,Duvvuri U

    更新日期:2017-11-09 00:00:00

  • Genome-wide analysis of horizontally acquired genes in the genus Mycobacterium.

    abstract::Horizontal gene transfer (HGT) was attributed as a major driving force for the innovation and evolution of prokaryotic genomes. Previously, multiple research endeavors were undertaken to decipher HGT in different bacterial lineages. The genus Mycobacterium houses some of the most deadly human pathogens; however, the i...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-33261-w

    authors: Panda A,Drancourt M,Tuller T,Pontarotti P

    更新日期:2018-10-04 00:00:00

  • The coupling of Phanerozoic continental weathering and marine phosphorus cycle.

    abstract::Organic matter production and decomposition primarily modulate the atmospheric O2 and CO2 levels. The long term marine primary productivity is controlled by the terrestrial input of phosphorus (P), while the marine P cycle would also affect organic matter production. In the past 540 million years, the evolution of ter...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-62816-z

    authors: Wang R,Lang X,Ding W,Liu Y,Huang T,Tang W,Shen B

    更新日期:2020-04-02 00:00:00

  • CD36 is expressed in a defined subpopulation of neurons in the olfactory epithelium.

    abstract::The sensory neurons in the olfactory epithelium (OSNs) are equipped with a large repertoire of olfactory receptors and the associated signal transduction machinery. In addition to the canonical OSNs, which express odorant receptors (ORs), the epithelium contains specialized subpopulations of sensory neurons that can d...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25507

    authors: Xavier AM,Ludwig RG,Nagai MH,de Almeida TJ,Watanabe HM,Hirata MY,Rosenstock TR,Papes F,Malnic B,Glezer I

    更新日期:2016-05-05 00:00:00

  • Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue.

    abstract::In comparison to genome-wide association studies (GWAS), there has been poor replication of gene expression studies in chronic obstructive pulmonary disease (COPD). We performed microarray gene expression profiling on a large sample of resected lung tissues from subjects with severe COPD. Comparing 111 COPD cases and ...

    journal_title:Scientific reports

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1038/srep44232

    authors: Morrow JD,Zhou X,Lao T,Jiang Z,DeMeo DL,Cho MH,Qiu W,Cloonan S,Pinto-Plata V,Celli B,Marchetti N,Criner GJ,Bueno R,Washko GR,Glass K,Quackenbush J,Choi AM,Silverman EK,Hersh CP

    更新日期:2017-03-13 00:00:00

  • White matter microstructure is associated with functional, cognitive and emotional symptoms 12 months after mild traumatic brain injury.

    abstract::Identifying patients at risk of poor outcome after mild traumatic brain injury (MTBI) is essential to aid prognostics and treatment. Diffuse axonal injury (DAI) may be the primary pathologic feature of MTBI but is normally not detectable by conventional imaging technology. This lack of sensitivity of clinical imaging ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-13628-1

    authors: Hellstrøm T,Westlye LT,Kaufmann T,Trung Doan N,Søberg HL,Sigurdardottir S,Nordhøy W,Helseth E,Andreassen OA,Andelic N

    更新日期:2017-10-23 00:00:00

  • RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143.

    abstract::Nitric oxide (NO)-induced apoptosis in neurons is an important cause of neurodegenerative disease in humans. The cold-inducible protein RBM3 mediates the protective effects of cooling on apoptosis induced by various insults. However, whether RBM3 protects neural cells from NO-induced apoptosis is unclear. This study a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41738

    authors: Yang HJ,Ju F,Guo XX,Ma SP,Wang L,Cheng BF,Zhuang RJ,Zhang BB,Shi X,Feng ZW,Wang M

    更新日期:2017-01-30 00:00:00

  • Epitope mapping of diverse influenza Hemagglutinin drug candidates using HDX-MS.

    abstract::Epitope characterization is critical for elucidating the mechanism of action of drug candidates. However, traditional high-resolution epitope mapping techniques are not well suited for screening numerous drug candidates recognizing a similar target. Here, we use Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-41179-0

    authors: Puchades C,Kűkrer B,Diefenbach O,Sneekes-Vriese E,Juraszek J,Koudstaal W,Apetri A

    更新日期:2019-03-18 00:00:00

  • Tailoring Plasmonic Enhanced Upconversion in Single NaYF4:Yb(3+)/Er(3+) Nanocrystals.

    abstract::By using silver nanoplatelets with a widely tunable localized surface plasmon resonance (LSPR), and their corresponding local field enhancement, here we show large manipulation of plasmonic enhanced upconversion in NaYF4:Yb(3+)/Er(3+) nanocrystals at the single particle level. In particular, we show that when the plas...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep10196

    authors: Wang YL,Mohammadi Estakhri N,Johnson A,Li HY,Xu LX,Zhang Z,Alù A,Wang QQ,Shih CK

    更新日期:2015-05-15 00:00:00

  • Reduction in Urinary Chemokine (C-C Motif) Ligand 2 (CCL2) After Surgery-Induced Weight Loss.

    abstract::Kidney dysfunction, a deleterious effect of obesity, is now recognized as a relevant health risk. Chemokine (C-C Motif) Ligand 2 (CCL2) is one of the critical chemokines that play a vital role in the development of obesity-related metabolic disease. We aim to measure the changes in urinary CCL2 in our patients before ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-57763-8

    authors: Said SB,Loo GH,Kosai NR,Rajan R,Mohd R,Wahab AA,Shah SA

    更新日期:2020-01-21 00:00:00

  • Transcriptome analyses suggest a novel hypothesis for whitefly adaptation to tobacco.

    abstract::The adaptation of herbivorous insects to various host plants facilitates the spread and outbreak of many important invasive pests, however, the molecular mechanisms that underneath this process are poorly understood. In the past three decades, two species of the whitefly Bemisia tabaci complex, Middle East-Asia Minor ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-12387-3

    authors: Xia WQ,Wang XR,Liang Y,Liu SS,Wang XW

    更新日期:2017-09-21 00:00:00

  • A mechanism of glucose tolerance and stimulation of GH1 β-glucosidases.

    abstract::β-Glucosidases are enzymes that hydrolyze β-glycosidic bonds to release non-reducing terminal glucosyl residues from glycosides and oligosaccharides, and thus have significant application potential in industries. However, most β-glucosidases are feedback inhibited by the glucose product, which restricts their applicat...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep17296

    authors: Yang Y,Zhang X,Yin Q,Fang W,Fang Z,Wang X,Zhang X,Xiao Y

    更新日期:2015-11-25 00:00:00

  • ATR-FTIR spectral discrimination between normal and tumorous mouse models of lymphoma and melanoma from serum samples.

    abstract::This study presents, attenuated total reflection Fourier transforms infrared spectroscopy of dried serum samples in an effort to assess biochemical changes induced by non-Hodgkin's lymphoma and subcutaneous melanoma. An EL4 mouse model of non-Hodgkin lymphoma and a B16 mouse model of subcutaneous melanoma are used to ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-17027-4

    authors: Ghimire H,Venkataramani M,Bian Z,Liu Y,Perera AGU

    更新日期:2017-12-05 00:00:00

  • Tetrameric structure of the restriction DNA glycosylase R.PabI in complex with nonspecific double-stranded DNA.

    abstract::R.PabI is a type II restriction enzyme that recognizes the 5'-GTAC-3' sequence and belongs to the HALFPIPE superfamily. Although most restriction enzymes cleave phosphodiester bonds at specific sites by hydrolysis, R.PabI flips the guanine and adenine bases of the recognition sequence out of the DNA helix and hydrolyz...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep35197

    authors: Wang D,Miyazono KI,Tanokura M

    更新日期:2016-10-12 00:00:00

  • Selective effect of cell membrane on synaptic neurotransmission.

    abstract::Atomistic molecular dynamics simulations were performed with 13 non-peptidic neurotransmitters (NTs) in three different membrane environments. The results provide compelling evidence that NTs are divided into membrane-binding and membrane-nonbinding molecules. NTs adhere to the postsynaptic membrane surface whenever t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep19345

    authors: Postila PA,Vattulainen I,Róg T

    更新日期:2016-01-19 00:00:00

  • Electrochemical analysis of anionic analytes in weakly supported media using electron transfer promotion effect: a case study on nitrite.

    abstract::In this study, a simple technique was developed for the electrochemical detection of anionic analytes in weakly supported media. This was conducted by the use of electrochemical paper-based analytical devices (ePADs). A sensing platform was modified with nereistoxin and used to determine nitrite as a case study. The e...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-71365-4

    authors: Khoshroo A,Fattahi A

    更新日期:2020-09-03 00:00:00

  • Systematized reporter assays reveal ZIC protein regulatory abilities are Subclass-specific and dependent upon transcription factor binding site context.

    abstract::The ZIC proteins are a family of transcription regulators with a well-defined zinc finger DNA-binding domain and there is evidence that they elicit functional DNA binding at a ZIC DNA binding site. Little is known, however, regarding domains within ZIC proteins that confer trans-activation or -repression. To address t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-69917-9

    authors: Ahmed JN,Diamand KEM,Bellchambers HM,Arkell RM

    更新日期:2020-08-04 00:00:00

  • Interactions among Drosophila larvae before and during collision.

    abstract::In populations of Drosophila larvae, both, an aggregation and a dispersal behavior can be observed. However, the mechanisms coordinating larval locomotion in respect to other animals, especially in close proximity and during/after physical contacts are currently only little understood. Here we test whether relevant in...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep31564

    authors: Otto N,Risse B,Berh D,Bittern J,Jiang X,Klämbt C

    更新日期:2016-08-11 00:00:00

  • A Strategy to enhance Eu3+ emission from LiYF4:Eu nanophosphors and green-to-orange multicolor tunable, transparent nanophosphor-polymer composites.

    abstract::LiYF4:Eu nanophosphors with a single tetragonal phase are synthesized, and various strategies to enhance the Eu(3+) emission from the nanophosphors are investigated. The optimized Eu(3+) concentration is 35 mol%, and the red emission peaks due to the (5)D0 →(7)FJ (J = 1 and 2) transitions of Eu(3+) ions are further en...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep07866

    authors: Kim SY,Won YH,Jang HS

    更新日期:2015-01-19 00:00:00

  • The secreted Ly6/uPAR-related protein-1 suppresses neutrophil binding, chemotaxis, and transmigration through human umbilical vein endothelial cells.

    abstract::The secreted Ly-6/uPAR Related Protein-1 (SLURP1) is an immunomodulatory protein that promotes corneal immune- and angiogenic-privilege. Here, we have examined the influence of SLURP1 on neutrophil-vascular endothelial cell interactions using human umbilical vein endothelial cells (HUVEC) and differentiated neutrophil...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-42437-x

    authors: Swamynathan S,Tiwari A,Loughner CL,Gnalian J,Alexander N,Jhanji V,Swamynathan SK

    更新日期:2019-04-11 00:00:00

  • Role of oxidants in enhancing dewaterability of anaerobically digested sludge through Fe (II) activated oxidation processes: hydrogen peroxide versus persulfate.

    abstract::Improving dewaterability of sludge is important for the disposal of sludge in wastewater treatment plants (WWTPs). This study, for the first time, investigated the Fe(II) activated oxidization processes in improving anaerobically digested sludge (ADS) dewaterability. The combination of Fe(II) (0-100 mg/g total solids ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep24800

    authors: Song K,Zhou X,Liu Y,Gong Y,Zhou B,Wang D,Wang Q

    更新日期:2016-04-25 00:00:00

  • Soil pH is equally important as salinity in shaping bacterial communities in saline soils under halophytic vegetation.

    abstract::While saline soils account for 6.5% of the total land area globally, it comprises about 70% of the area in northwestern China. Microbiota in these saline soils are particularly important because they are critical to maintaining ecosystem services. However, little is known about the microbial diversity and community co...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-22788-7

    authors: Zhao S,Liu JJ,Banerjee S,Zhou N,Zhao ZY,Zhang K,Tian CY

    更新日期:2018-03-14 00:00:00

  • Metallothionein Genes are Highly Expressed in Malignant Astrocytomas and Associated with Patient Survival.

    abstract::Gliomas are heterogeneous, primary brain tumours that originate from glial cells. The main type of gliomas is astrocytomas. There are four grades (I-IV) of astrocytoma malignancy. Astrocytoma grade IV known as glioblastoma multiforme (GBM) is the most common and aggressive type of astrocytic gliomas. Metallothioneins ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-41974-9

    authors: Masiulionytė B,Valiulytė I,Tamašauskas A,Skiriutė D

    更新日期:2019-04-01 00:00:00

  • The Natural Course of Intermittent Exotropia over a 3-year Period and the Factors Predicting the Control Deterioration.

    abstract::The natural course of intermittent exotropia and the factors affecting its control has been unclear. We aim to report the natural course of our cohort of 117 Chinese children with intermittent exotropia and to identify baseline parameters that may have predictive value in the control deterioration of the disease. The ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep27113

    authors: Kwok JJ,Chong GS,Ko ST,Yam JC

    更新日期:2016-06-03 00:00:00

  • Altered brain activation and functional connectivity in working memory related networks in patients with type 2 diabetes: An ICA-based analysis.

    abstract::Type 2 diabetes mellitus (T2DM) can cause multidimensional cognitive deficits, among which working memory (WM) is usually involved at an early stage. However, the neural substrates underlying impaired WM in T2DM patients are still unclear. To clarify this issue, we utilized functional magnetic resonance imaging (fMRI)...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep23767

    authors: Zhang Y,Lu S,Liu C,Zhang H,Zhou X,Ni C,Qin W,Zhang Q

    更新日期:2016-03-29 00:00:00

  • FAD104, a regulator of adipogenesis, is a novel suppressor of TGF-β-mediated EMT in cervical cancer cells.

    abstract::Epithelial-to-mesenchymal transition (EMT) is a biological process in which epithelial cells translate into a mesenchymal phenotype with invasive capacities, contributing to tumour progression, metastasis, and the acquisition of chemotherapy resistance. To identify new therapeutic targets for cancers, it is important ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-16555-3

    authors: Goto M,Osada S,Imagawa M,Nishizuka M

    更新日期:2017-11-27 00:00:00