TOR dynamically regulates plant cell-cell transport.

Abstract:

:The coordinated redistribution of sugars from mature "source" leaves to developing "sink" leaves requires tight regulation of sugar transport between cells via plasmodesmata (PD). Although fundamental to plant physiology, the mechanisms that control PD transport and thereby support development of new leaves have remained elusive. From a forward genetic screen for altered PD transport, we discovered that the conserved eukaryotic glucose-TOR (TARGET OF RAPAMYCIN) metabolic signaling network restricts PD transport in leaves. Genetic approaches and chemical or physiological treatments to either promote or disrupt TOR activity demonstrate that glucose-activated TOR decreases PD transport in leaves. We further found that TOR is significantly more active in mature leaves photosynthesizing excess sugars than in young, growing leaves, and that this increase in TOR activity correlates with decreased rates of PD transport. We conclude that leaf cells regulate PD trafficking in response to changing carbohydrate availability monitored by the TOR pathway.

authors

Brunkard JO,Xu M,Scarpin MR,Chatterjee S,Shemyakina EA,Goodman HM,Zambryski P

doi

10.1073/pnas.1919196117

subject

Has Abstract

pub_date

2020-03-03 00:00:00

pages

5049-5058

issue

9

eissn

0027-8424

issn

1091-6490

pii

1919196117

journal_volume

117

pub_type

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