Abstract:
BACKGROUND:For women with hormone receptor positive breast cancer, long-term endocrine therapy (ET) can greatly reduce the risk of recurrence, yet adherence is low- particularly among traditionally underserved populations. METHODS:The Carolina Breast Cancer Study oversampled Black and young women (<50 years of age). Participants answered an ET-specific medication adherence questionnaire assessing reasons for non-adherence. We used principal factor analysis to identify latent factors describing ET non-adherence. We then performed multivariable regression to determine clinical and demographic characteristics associated with each ET non-adherence factor. RESULTS:1,231 women were included in analysis, 59% reported at least one barrier to ET adherence. We identified three latent factors which we defined as: habit - challenges developing medication-taking behavior; tradeoffs - high perceived side effect burden and medication safety concerns; and resource barriers - challenges related to cost or accessibility. Older age (50+) was associated with less reporting of habit (Adjusted Risk Ratio (aRR) 0.54[95% CI: 0.43-0.69] and resource barriers (aRR 0.66[0.43-0.997]), but was not associated with tradeoff barriers. Medicaid-insured women were more likely than privately-insured to report tradeoff (aRR:1.53 [1.10-2.13]) or resource barriers (aRR:4.43[2.49-6.57]). Black race was associated with increased reporting of all factors (habit: aRR 1.29[1.09-1.53]; tradeoffs: 1.32[1.09-1.60], resources: 1.65[1.18-2.30]). CONCLUSION:Barriers to ET adherence were described by three distinct factors, and strongly associated with sociodemographic characteristics. Barriers to ET adherence appear inadequately addressed for younger, Black, and publicly-insured breast cancer survivors. These findings underscore the importance of developing multi-faceted, patient-centered interventions that address a diverse range of barriers to ET adherence.
journal_name
Psychooncologyjournal_title
Psycho-oncologyauthors
Spencer JC,Reeve BB,Troester MA,Wheeler SBdoi
10.1002/pon.5289subject
Has Abstractpub_date
2020-04-01 00:00:00pages
647-654issue
4eissn
1057-9249issn
1099-1611journal_volume
29pub_type
杂志文章相关文献
PSYCHO-ONCOLOGY文献大全abstract::An overview of drug metabolism, with particular focus on the cytochrome p450 system, is provided in this review. To date, there has been a growing body of literature concerning the cytochrome p450 enzyme, drug-drug interactions and the role of psychotropic medications when co-administered with medications prescribed i...
journal_title:Psycho-oncology
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1099-1611(199807/08)7:4<307::AID-PON
更新日期:1998-07-01 00:00:00
abstract:OBJECTIVE:Parents often feel ill-equipped to prepare their dependent children (<18 years old) for the death of a parent, necessitating support from professionals. The aim of this study is to explore health and social care professionals' (HSCPs) experiences and perceptions of providing supportive care to parents regardi...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.5581
更新日期:2020-10-22 00:00:00
abstract:BACKGROUND:Fear of recurrence (FOR) has been increasingly recognised as an issue of significant burden for most cancer patients, and has been associated with psychological morbidity and reduced quality of life. More recently, the impact of recurrence fears has been indicated in the families of cancer patients. However,...
journal_title:Psycho-oncology
pub_type: 杂志文章,多中心研究
doi:10.1002/pon.1346
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:Specialized palliative care (SPC) interventions increasingly include patient-caregiver dyads, but their effects on dyadic coping are unknown. We investigated whether an SPC and dyadic psychological intervention increased aspects of dyadic coping in patients with advanced cancer and their caregivers, whether d...
journal_title:Psycho-oncology
pub_type: 杂志文章,随机对照试验
doi:10.1002/pon.4932
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to describe the experiences of Korean family caregivers of patients with cancer by reviewing recent literature. METHODS:Five electronic databases were searched-MEDLINE, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), and PubMed for English literature, and ...
journal_title:Psycho-oncology
pub_type: 杂志文章,评审
doi:10.1002/pon.5498
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:Side effects of cancer treatment have been found to have a significant impact on patients' psychological well-being. Each of the primary treatment options for prostate cancer is associated with significant side effects that can have a dramatic impact on quality of life. Hot flashes are a notable side effect o...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.1427
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Partners of cancer patients typically provide the majority of patients' emotional and physical care. Partners may be profoundly affected by the cancer and may experience ongoing supportive care needs across the survivorship continuum. Research has been restricted by a lack of psychometrically evaluated measu...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.1138
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:Population-based data on the epidemiology of psychiatric disorders in patients with breast cancer are lacking. Because the National Health Insurance (NHI) Program in South Korea is a compulsory social insurance system covering the entire Korean population, the NHI is a good source of information for epidemiol...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.3369
更新日期:2014-01-01 00:00:00
abstract::Recent research in psychosocial oncology has pointed to the traumatic nature of the stress experienced by cancer survivors. Most of this research has focused on children, young adults survivors and their families. This investigation proposes a conceptual model for understanding general psychological distress (anxiety,...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.614
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVE:In the present study, we aimed to assess hostility and to examine its association with formal psychiatric diagnosis, coping, cancer worries, and quality of life in cancer patients. METHODS:The World Health Organization (WHO) Composite International Diagnostic Interview (CIDI) to make an ICD-10 (International...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.5594
更新日期:2020-11-18 00:00:00
abstract:BACKGROUND:Most quality-of-life (QoL) studies in autologous Peripheral Blood Stem Cell Transplantation (PBSCT) are descriptive and concentrate on symptom severity and functional deficits. The aim of this study is to compare individual QoL (iQoL) with health-related QoL (hrQoL) and functional status of patients before h...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.730
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVES:The nature and magnitude of the problems facing caregivers remain largely unknown in developing countries of the world. This study addresses these issues in a group of caregivers of patients with cancer in Zaria, Nigeria. METHOD:One hundred and three patients attending an oncology outpatient clinic at the A...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.1814
更新日期:2011-08-01 00:00:00
abstract::Consistent with the International Psycho-Oncology Society's (IPOS) vision and goals, we are committed to improving quality cancer care and cancer policies through psychosocial care globally. As part of IPOS's mission, upon entering "Official Relations" for a second term with the World Health Organization (WHO), IPOS h...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.4471
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:While the physical and psychosocial benefits of participating in physical activity (PA) during and following breast cancer treatment are well understood, less is known about rates and uptake of PA following diagnosis. This paper explores the levels and patterns of PA among women recently diagnosed with breast...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.1504
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:To examine current financial status, changes before and after bereavement, and their effects on possible major depressive disorder (MDD) and complicated grief (CG) among bereaved family members of patients with cancer. METHODS:We conducted a nationwide cross-sectional questionnaire survey on 787 bereaved fam...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.5642
更新日期:2021-01-28 00:00:00
abstract::Cancer patients diagnosed with solid tumors and undergoing a first course of chemotherapy were randomized to either conventional care or a 10 contact 20 week cognitive behavioral intervention designed to reduce emotional distress. Three hypotheses were tested. First, a test for a group effect found that patients in th...
journal_title:Psycho-oncology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/pon.807
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:A cancer diagnosis can have a profound impact on partners and close family members of patients. Little is currently known about the long-term impact. OBJECTIVES:The objective of this study is to describe health status, levels of anxiety and depression, unmet supportive care needs and positive outcomes in th...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.2050
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:Quality of life (QOL) and psychological distress at end of life (EOL) heavily depend on symptom distress and functional impairment, which may not deteriorate synchronously at EOL. METHODS:Using multivariate hierarchical linear modeling, we simultaneously evaluated the differential association of 5 previously...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.4775
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVES:The review aims to identify available evidence related to the effects of dignity therapy on dignity, psychological well-being, and quality of life (QoL) among patients with cancer under palliative care. METHODS:Thirteen electronic databases were searched for published articles in English or Chinese from inc...
journal_title:Psycho-oncology
pub_type: 杂志文章,meta分析
doi:10.1002/pon.5162
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:This longitudinal study investigated pre-screening factors that predicted breast cancer-specific distress among 1286 women who were undergoing annual mammography screening as part of a UK programme for younger women (i.e., under 50) with a family history of breast cancer. METHODS:Women completed questionnair...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.1355
更新日期:2008-12-01 00:00:00
abstract::The purpose of this study was to examine the role of spirituality in terminally ill cancer patients who volunteer for clinical trials of experimental agents. Information about spirituality (FACIT-Sp), quality of life (FACT-G), awareness of prognosis, and decision-making preferences was obtained from 162 advanced cance...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.829
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:This study was performed to explore in-depth, the issues and barriers pertaining to colorectal cancer (CRC) screening amongst the siblings of CRC patients in view of their higher risk of developing CRC. METHODS:A qualitative study of siblings of CRC patients was performed from August 2017 to October 2018. Se...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.5496
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:To examine cancer-related worry in adolescent and young adult (AYA) cancer survivors and its relationship with posttraumatic growth over time, as the relationship between these constructs has not been assessed longitudinally in this population. METHODS:A total of 153 AYA cancer survivors completed measures ...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.4785
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Some patients with prostate cancer regret their treatment choice. Treatment regret is associated with lower physical and mental quality of life. We investigated whether, in men with prostate cancer, spirituality is associated with lower decisional regret 6 months after treatment and whether this is, in part,...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.4248
更新日期:2017-11-01 00:00:00
abstract::In a consecutive sample of 100 breast cancer patients undergoing radiotherapy, cancer-related distress was assessed with the Hospital Anxiety and Depression Scale and patients' interest in and acceptance of psychosocial support with the Questionnaire for Psychosocial Support and the European Consultation Liaison Workg...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.867
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:The 12-item Functional Assessment of Chronic Illness Therapy-Spiritual Well-being Scale (FACIT-Sp) is a popular measure of the religious/spiritual (R/S) components of quality of life (QoL) in patients with cancer. The original factor analyses of the FACIT-Sp supported two factors: Meaning/Peace and Faith. Bec...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.1307
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:A diagnosis of breast cancer disrupts the life of the patient, but also the partner may experience adverse psychological effects. We examined partners' risk for first use of antidepressant medication, as a proxy for pharmacologically treated depression. METHODS:By linkage of national registers, we identified...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.4459
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:This study aimed to systematically review and synthesise qualitative studies of employment and cancer. METHODS:A rigorous systematic review and meta-synthesis process was followed. A total of 13,233 papers were retrieved from eight databases; 69 were deemed relevant following title and abstract appraisal. F...
journal_title:Psycho-oncology
pub_type: 杂志文章,meta分析,评审
doi:10.1002/pon.3148
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:The relation between posttraumatic growth (PTG) and aspects of the social context, such as social support and social constraint, continues to be unclear in cancer survivors. Social cognitive processing theory is a useful framework for examining the effect of the social context on PTG. In theory, support inter...
journal_title:Psycho-oncology
pub_type: 杂志文章
doi:10.1002/pon.2073
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To systematically review psycho-educational interventions developed for melanoma survivors. METHODS:Electronic databases Medline, PsycINFO, Embase, and CINAHL were systematically searched using key words and subject headings for articles describing educational or psychological interventions designed specific...
journal_title:Psycho-oncology
pub_type: 杂志文章,评审
doi:10.1002/pon.3165
更新日期:2013-07-01 00:00:00