Factors Associated with Endocrine Therapy Non-Adherence in Breast Cancer Survivors.

Abstract:

BACKGROUND:For women with hormone receptor positive breast cancer, long-term endocrine therapy (ET) can greatly reduce the risk of recurrence, yet adherence is low- particularly among traditionally underserved populations. METHODS:The Carolina Breast Cancer Study oversampled Black and young women (<50 years of age). Participants answered an ET-specific medication adherence questionnaire assessing reasons for non-adherence. We used principal factor analysis to identify latent factors describing ET non-adherence. We then performed multivariable regression to determine clinical and demographic characteristics associated with each ET non-adherence factor. RESULTS:1,231 women were included in analysis, 59% reported at least one barrier to ET adherence. We identified three latent factors which we defined as: habit - challenges developing medication-taking behavior; tradeoffs - high perceived side effect burden and medication safety concerns; and resource barriers - challenges related to cost or accessibility. Older age (50+) was associated with less reporting of habit (Adjusted Risk Ratio (aRR) 0.54[95% CI: 0.43-0.69] and resource barriers (aRR 0.66[0.43-0.997]), but was not associated with tradeoff barriers. Medicaid-insured women were more likely than privately-insured to report tradeoff (aRR:1.53 [1.10-2.13]) or resource barriers (aRR:4.43[2.49-6.57]). Black race was associated with increased reporting of all factors (habit: aRR 1.29[1.09-1.53]; tradeoffs: 1.32[1.09-1.60], resources: 1.65[1.18-2.30]). CONCLUSION:Barriers to ET adherence were described by three distinct factors, and strongly associated with sociodemographic characteristics. Barriers to ET adherence appear inadequately addressed for younger, Black, and publicly-insured breast cancer survivors. These findings underscore the importance of developing multi-faceted, patient-centered interventions that address a diverse range of barriers to ET adherence.

journal_name

Psychooncology

journal_title

Psycho-oncology

authors

Spencer JC,Reeve BB,Troester MA,Wheeler SB

doi

10.1002/pon.5289

subject

Has Abstract

pub_date

2020-04-01 00:00:00

pages

647-654

issue

4

eissn

1057-9249

issn

1099-1611

journal_volume

29

pub_type

杂志文章
  • Psychotropic drug metabolism in the cancer patient: clinical aspects of management of potential drug interactions.

    abstract::An overview of drug metabolism, with particular focus on the cytochrome p450 system, is provided in this review. To date, there has been a growing body of literature concerning the cytochrome p450 enzyme, drug-drug interactions and the role of psychotropic medications when co-administered with medications prescribed i...

    journal_title:Psycho-oncology

    pub_type: 杂志文章,评审

    doi:10.1002/(SICI)1099-1611(199807/08)7:4<307::AID-PON

    authors: Kalash GR

    更新日期:1998-07-01 00:00:00

  • Providing care to parents dying from cancer with dependent children: Health and social care professionals' experience.

    abstract:OBJECTIVE:Parents often feel ill-equipped to prepare their dependent children (<18 years old) for the death of a parent, necessitating support from professionals. The aim of this study is to explore health and social care professionals' (HSCPs) experiences and perceptions of providing supportive care to parents regardi...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.5581

    authors: Hanna JR,McCaughan E,Beck ER,Semple CJ

    更新日期:2020-10-22 00:00:00

  • Fear of recurrence and psychological distress in head and neck cancer patients and their carers.

    abstract:BACKGROUND:Fear of recurrence (FOR) has been increasingly recognised as an issue of significant burden for most cancer patients, and has been associated with psychological morbidity and reduced quality of life. More recently, the impact of recurrence fears has been indicated in the families of cancer patients. However,...

    journal_title:Psycho-oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/pon.1346

    authors: Hodges LJ,Humphris GM

    更新日期:2009-08-01 00:00:00

  • Dyadic coping in specialized palliative care intervention for patients with advanced cancer and their caregivers: Effects and mediation in a randomized controlled trial.

    abstract:OBJECTIVE:Specialized palliative care (SPC) interventions increasingly include patient-caregiver dyads, but their effects on dyadic coping are unknown. We investigated whether an SPC and dyadic psychological intervention increased aspects of dyadic coping in patients with advanced cancer and their caregivers, whether d...

    journal_title:Psycho-oncology

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/pon.4932

    authors: von Heymann-Horan A,Bidstrup PE,Johansen C,Rottmann N,Andersen EAW,Sjøgren P,von der Maase H,Timm H,Kjellberg J,Guldin MB

    更新日期:2019-02-01 00:00:00

  • Caregiving experiences of Korean family caregivers of cancer patients: An integrative literature review.

    abstract:OBJECTIVE:The purpose of this study was to describe the experiences of Korean family caregivers of patients with cancer by reviewing recent literature. METHODS:Five electronic databases were searched-MEDLINE, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), and PubMed for English literature, and ...

    journal_title:Psycho-oncology

    pub_type: 杂志文章,评审

    doi:10.1002/pon.5498

    authors: Lee EE,Lee SY

    更新日期:2020-10-01 00:00:00

  • Relationship between hot flashes and distress in men receiving androgen deprivation therapy for prostate cancer.

    abstract:OBJECTIVE:Side effects of cancer treatment have been found to have a significant impact on patients' psychological well-being. Each of the primary treatment options for prostate cancer is associated with significant side effects that can have a dramatic impact on quality of life. Hot flashes are a notable side effect o...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.1427

    authors: Ulloa EW,Salup R,Patterson SG,Jacobsen PB

    更新日期:2009-06-01 00:00:00

  • Assessing unmet supportive care needs in partners of cancer survivors: the development and evaluation of the Cancer Survivors' Partners Unmet Needs measure (CaSPUN).

    abstract:BACKGROUND:Partners of cancer patients typically provide the majority of patients' emotional and physical care. Partners may be profoundly affected by the cancer and may experience ongoing supportive care needs across the survivorship continuum. Research has been restricted by a lack of psychometrically evaluated measu...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.1138

    authors: Hodgkinson K,Butow P,Hobbs KM,Hunt GE,Lo SK,Wain G

    更新日期:2007-09-01 00:00:00

  • The epidemiology of psychiatric disorders among women with breast cancer in South Korea: analysis of national registry data.

    abstract:OBJECTIVE:Population-based data on the epidemiology of psychiatric disorders in patients with breast cancer are lacking. Because the National Health Insurance (NHI) Program in South Korea is a compulsory social insurance system covering the entire Korean population, the NHI is a good source of information for epidemiol...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.3369

    authors: Kang JI,Sung NY,Park SJ,Lee CG,Lee BO

    更新日期:2014-01-01 00:00:00

  • Cancer survivorship and psychological distress in later life.

    abstract::Recent research in psychosocial oncology has pointed to the traumatic nature of the stress experienced by cancer survivors. Most of this research has focused on children, young adults survivors and their families. This investigation proposes a conceptual model for understanding general psychological distress (anxiety,...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.614

    authors: Deimling GT,Kahana B,Bowman KF,Schaefer ML

    更新日期:2002-11-01 00:00:00

  • Hostility in cancer patients as an underexplored facet of distress.

    abstract:OBJECTIVE:In the present study, we aimed to assess hostility and to examine its association with formal psychiatric diagnosis, coping, cancer worries, and quality of life in cancer patients. METHODS:The World Health Organization (WHO) Composite International Diagnostic Interview (CIDI) to make an ICD-10 (International...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.5594

    authors: Grassi L,Belvederi Murri M,Riba M,de Padova S,Bertelli T,Sabato S,Nanni MG,Caruso R,Ounalli H,Zerbinati L

    更新日期:2020-11-18 00:00:00

  • Individual quality of life of patients undergoing autologous peripheral blood stem cell transplantation.

    abstract:BACKGROUND:Most quality-of-life (QoL) studies in autologous Peripheral Blood Stem Cell Transplantation (PBSCT) are descriptive and concentrate on symptom severity and functional deficits. The aim of this study is to compare individual QoL (iQoL) with health-related QoL (hrQoL) and functional status of patients before h...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.730

    authors: Frick E,Borasio GD,Zehentner H,Fischer N,Bumeder I

    更新日期:2004-02-01 00:00:00

  • Caregiver burden among poor caregivers of patients with cancer in an urban African setting.

    abstract:OBJECTIVES:The nature and magnitude of the problems facing caregivers remain largely unknown in developing countries of the world. This study addresses these issues in a group of caregivers of patients with cancer in Zaria, Nigeria. METHOD:One hundred and three patients attending an oncology outpatient clinic at the A...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.1814

    authors: Yusuf AJ,Adamu A,Nuhu FT

    更新日期:2011-08-01 00:00:00

  • 2016 President's Plenary International Psycho-Oncology Society: challenges and opportunities for growing and developing psychosocial oncology programmes worldwide.

    abstract::Consistent with the International Psycho-Oncology Society's (IPOS) vision and goals, we are committed to improving quality cancer care and cancer policies through psychosocial care globally. As part of IPOS's mission, upon entering "Official Relations" for a second term with the World Health Organization (WHO), IPOS h...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.4471

    authors: Travado L,Bultz BD,Ullrich A,Asuzu CC,Turner J,Grassi L,Jacobsen P

    更新日期:2017-09-01 00:00:00

  • Level of physical activity and characteristics associated with change following breast cancer diagnosis and treatment.

    abstract:OBJECTIVE:While the physical and psychosocial benefits of participating in physical activity (PA) during and following breast cancer treatment are well understood, less is known about rates and uptake of PA following diagnosis. This paper explores the levels and patterns of PA among women recently diagnosed with breast...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.1504

    authors: Harrison S,Hayes SC,Newman B

    更新日期:2009-04-01 00:00:00

  • Effects of financial status on major depressive disorder and complicated grief among bereaved family members of patients with cancer.

    abstract:OBJECTIVE:To examine current financial status, changes before and after bereavement, and their effects on possible major depressive disorder (MDD) and complicated grief (CG) among bereaved family members of patients with cancer. METHODS:We conducted a nationwide cross-sectional questionnaire survey on 787 bereaved fam...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.5642

    authors: Aoyama M,Sakaguchi Y,Igarashi N,Morita T,Shima Y,Miyashita M

    更新日期:2021-01-28 00:00:00

  • Does a symptom management intervention affect depression among cancer patients: results from a clinical trial.

    abstract::Cancer patients diagnosed with solid tumors and undergoing a first course of chemotherapy were randomized to either conventional care or a 10 contact 20 week cognitive behavioral intervention designed to reduce emotional distress. Three hypotheses were tested. First, a test for a group effect found that patients in th...

    journal_title:Psycho-oncology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/pon.807

    authors: Given C,Given B,Rahbar M,Jeon S,McCorkle R,Cimprich B,Galecki A,Kozachik S,Devoss D,Brady A,Fisher-Malloy MJ,Courtney K,Bowie E

    更新日期:2004-11-01 00:00:00

  • Partners and close family members of long-term cancer survivors: health status, psychosocial well-being and unmet supportive care needs.

    abstract:BACKGROUND:A cancer diagnosis can have a profound impact on partners and close family members of patients. Little is currently known about the long-term impact. OBJECTIVES:The objective of this study is to describe health status, levels of anxiety and depression, unmet supportive care needs and positive outcomes in th...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.2050

    authors: Turner D,Adams E,Boulton M,Harrison S,Khan N,Rose P,Ward A,Watson EK

    更新日期:2013-01-01 00:00:00

  • Quality of life and psychological distress are differentially associated with distinct symptom-functional states in terminally ill cancer patients' last year of life.

    abstract:OBJECTIVE:Quality of life (QOL) and psychological distress at end of life (EOL) heavily depend on symptom distress and functional impairment, which may not deteriorate synchronously at EOL. METHODS:Using multivariate hierarchical linear modeling, we simultaneously evaluated the differential association of 5 previously...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.4775

    authors: Wen FH,Chen JS,Chou WC,Hsieh CH,Chang WC,Shen WC,Tang ST

    更新日期:2018-09-01 00:00:00

  • Effects of dignity therapy on dignity, psychological well-being, and quality of life among palliative care cancer patients: A systematic review and meta-analysis.

    abstract:OBJECTIVES:The review aims to identify available evidence related to the effects of dignity therapy on dignity, psychological well-being, and quality of life (QoL) among patients with cancer under palliative care. METHODS:Thirteen electronic databases were searched for published articles in English or Chinese from inc...

    journal_title:Psycho-oncology

    pub_type: 杂志文章,meta分析

    doi:10.1002/pon.5162

    authors: Xiao J,Chow KM,Liu Y,Chan CWH

    更新日期:2019-09-01 00:00:00

  • Predictors of breast cancer-related distress following mammography screening in younger women on a family history breast screening programme.

    abstract:OBJECTIVE:This longitudinal study investigated pre-screening factors that predicted breast cancer-specific distress among 1286 women who were undergoing annual mammography screening as part of a UK programme for younger women (i.e., under 50) with a family history of breast cancer. METHODS:Women completed questionnair...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.1355

    authors: Brain K,Henderson BJ,Tyndel S,Bankhead C,Watson E,Clements A,Austoker J,PIMMS Study Management Group.

    更新日期:2008-12-01 00:00:00

  • Trusting God and medicine: spirituality in advanced cancer patients volunteering for clinical trials of experimental agents.

    abstract::The purpose of this study was to examine the role of spirituality in terminally ill cancer patients who volunteer for clinical trials of experimental agents. Information about spirituality (FACIT-Sp), quality of life (FACT-G), awareness of prognosis, and decision-making preferences was obtained from 162 advanced cance...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.829

    authors: Daugherty CK,Fitchett G,Murphy PE,Peterman AH,Banik DM,Hlubocky F,Tartaro J

    更新日期:2005-02-01 00:00:00

  • Colorectal cancer patients can be advocates for colorectal cancer screening for their siblings: A study on siblings' perspectives.

    abstract:OBJECTIVE:This study was performed to explore in-depth, the issues and barriers pertaining to colorectal cancer (CRC) screening amongst the siblings of CRC patients in view of their higher risk of developing CRC. METHODS:A qualitative study of siblings of CRC patients was performed from August 2017 to October 2018. Se...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.5496

    authors: Tan KK,Lim TZ,Chew E,Chow WM,Koh GC

    更新日期:2020-12-01 00:00:00

  • The relationship between cancer-related worry and posttraumatic growth in adolescent and young adult cancer survivors.

    abstract:OBJECTIVES:To examine cancer-related worry in adolescent and young adult (AYA) cancer survivors and its relationship with posttraumatic growth over time, as the relationship between these constructs has not been assessed longitudinally in this population. METHODS:A total of 153 AYA cancer survivors completed measures ...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.4785

    authors: McDonnell GA,Pope AW,Schuler TA,Ford JS

    更新日期:2018-09-01 00:00:00

  • Spirituality is associated with less treatment regret in men with localized prostate cancer.

    abstract:BACKGROUND:Some patients with prostate cancer regret their treatment choice. Treatment regret is associated with lower physical and mental quality of life. We investigated whether, in men with prostate cancer, spirituality is associated with lower decisional regret 6 months after treatment and whether this is, in part,...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.4248

    authors: Mollica MA,Underwood W 3rd,Homish GG,Homish DL,Orom H

    更新日期:2017-11-01 00:00:00

  • Providing psychosocial support for breast cancer patients based on screening for distress within a consultation-liaison service.

    abstract::In a consecutive sample of 100 breast cancer patients undergoing radiotherapy, cancer-related distress was assessed with the Hospital Anxiety and Depression Scale and patients' interest in and acceptance of psychosocial support with the Questionnaire for Psychosocial Support and the European Consultation Liaison Workg...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.867

    authors: Söllner W,Maislinger S,König A,Devries A,Lukas P

    更新日期:2004-12-01 00:00:00

  • A 3-factor model for the FACIT-Sp.

    abstract:OBJECTIVE:The 12-item Functional Assessment of Chronic Illness Therapy-Spiritual Well-being Scale (FACIT-Sp) is a popular measure of the religious/spiritual (R/S) components of quality of life (QoL) in patients with cancer. The original factor analyses of the FACIT-Sp supported two factors: Meaning/Peace and Faith. Bec...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.1307

    authors: Canada AL,Murphy PE,Fitchett G,Peterman AH,Schover LR

    更新日期:2008-09-01 00:00:00

  • First use of antidepressant medication in male partners of women with breast cancer in Denmark from 1998 to 2011.

    abstract:OBJECTIVE:A diagnosis of breast cancer disrupts the life of the patient, but also the partner may experience adverse psychological effects. We examined partners' risk for first use of antidepressant medication, as a proxy for pharmacologically treated depression. METHODS:By linkage of national registers, we identified...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.4459

    authors: Cromhout PF,Latocha KM,Olsen MH,Suppli NP,Christensen J,Johansen C,Dalton SO

    更新日期:2017-12-01 00:00:00

  • Supporting 'work-related goals' rather than 'return to work' after cancer? A systematic review and meta-synthesis of 25 qualitative studies.

    abstract:BACKGROUND:This study aimed to systematically review and synthesise qualitative studies of employment and cancer. METHODS:A rigorous systematic review and meta-synthesis process was followed. A total of 13,233 papers were retrieved from eight databases; 69 were deemed relevant following title and abstract appraisal. F...

    journal_title:Psycho-oncology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1002/pon.3148

    authors: Wells M,Williams B,Firnigl D,Lang H,Coyle J,Kroll T,MacGillivray S

    更新日期:2013-06-01 00:00:00

  • Posttraumatic growth, social support, and social constraint in hematopoietic stem cell transplant survivors.

    abstract:OBJECTIVE:The relation between posttraumatic growth (PTG) and aspects of the social context, such as social support and social constraint, continues to be unclear in cancer survivors. Social cognitive processing theory is a useful framework for examining the effect of the social context on PTG. In theory, support inter...

    journal_title:Psycho-oncology

    pub_type: 杂志文章

    doi:10.1002/pon.2073

    authors: Nenova M,DuHamel K,Zemon V,Rini C,Redd WH

    更新日期:2013-01-01 00:00:00

  • Psycho-educational interventions for melanoma survivors: a systematic review.

    abstract:OBJECTIVE:To systematically review psycho-educational interventions developed for melanoma survivors. METHODS:Electronic databases Medline, PsycINFO, Embase, and CINAHL were systematically searched using key words and subject headings for articles describing educational or psychological interventions designed specific...

    journal_title:Psycho-oncology

    pub_type: 杂志文章,评审

    doi:10.1002/pon.3165

    authors: McLoone J,Menzies S,Meiser B,Mann GJ,Kasparian NA

    更新日期:2013-07-01 00:00:00