Abstract:
:The reproducibility crisis triggered worldwide initiatives to improve rigor, reproducibility, and transparency in biomedical research. There are many examples of scientists, journals, and funding agencies adopting responsible research practices. The QUEST (Quality-Ethics-Open Science-Translation) Center offers a unique opportunity to examine the role of institutions. The Berlin Institute of Health founded QUEST to increase the likelihood that research conducted at this large academic medical center would be trustworthy, useful for scientists and society, and ethical. QUEST researchers perform "science of science" studies to understand problems with standard practices and develop targeted solutions. The staff work with institutional leadership and local scientists to incentivize and support responsible practices in research, funding, and hiring. Some activities described in this paper focus on the institution, whereas others may benefit the national and international scientific community. Our experience, approaches, and recommendations will be informative for faculty leadership, administrators, and researchers interested in improving scientific practice.
journal_name
PLoS Bioljournal_title
PLoS biologyauthors
Strech D,Weissgerber T,Dirnagl U,QUEST Group.doi
10.1371/journal.pbio.3000576subject
Has Abstractpub_date
2020-02-11 00:00:00pages
e3000576issue
2eissn
1544-9173issn
1545-7885pii
PBIOLOGY-D-19-03177journal_volume
18pub_type
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