The efficacy and tolerability of febuxostat in gout patients on dialysis.

abstract：:Inappropriate polypharmacy and its associated harm pose a significant threat to older patients. The prescribing decisions of physicians greatly influence what other practitioners prescribe. Minimising medication-related harm requires physicians to adopt a systematic approach to the deliberate and judicious deprescribi...

journal_title：Internal medicine journal

authors： Scott IA,Le Couteur DG

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The relationship between serum triglycerides (TG) level and the risk of coronary heart disease (CHD) mortality remains controversial. AIMS:To evaluate whether TG level is a risk factor for CHD in elderly people from general population, and to look for interactions between TG and other risk factors. METHODS...

journal_title：Internal medicine journal

authors： Mazza A,Tikhonoff V,Schiavon L,Casiglia E

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Ageism among health professionals is increasingly recognized, but few studies investigated hospital doctors' attitudes towards older people. The aims of this study were to investigate hospital doctors' attitudes towards older people and to determine whether factors, which were identified in studies on other ...

journal_title：Internal medicine journal

authors： Leung S,Logiudice D,Schwarz J,Brand C

更新日期：2011-04-01 00:00:00

abstract：:Depression is the leading cause of non-fatal disease burden in Australia. Recently, increasing public recognition, together with the development of more integrated medical and psychological healthcare services has resulted in significant improvements. New pathophysiological models incorporate structural brain changes ...

journal_title：Internal medicine journal

authors： Hickie IB,Naismith SL,Norrie LM,Scott EM

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:The comparative effectiveness of biologic treatment regimens in a real world Australian population is unknown. AIM:To assess the effectiveness of biological disease-modifying anti-rheumatic drugs (bDMARD) as monotherapy or in combination with methotrexate and/or other conventional DMARD (cDMARD) for the tre...

journal_title：Internal medicine journal

authors： Nicholls D,Barrett R,Button P,Truman M,Bird P,Roberts L,Tymms K,Littlejohn G,Griffiths H

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Pulmonary embolism (PE) is associated with significant morbidity and mortality. PE is a heterogeneous entity that causes a wide variety of clinical presentations, making it imperative to establish which clinical symptoms, signs and biomarkers can influence the pretest probability of PE to aid clinicians and ...

journal_title：Internal medicine journal

authors： Sethwala A,Wang X,Sturm EE,Collins KL,O'Donnabhain R,Friedman ND

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Clopidogrel is an antiplatelet drug increasingly used in the secondary prevention of atherosclerotic vascular events. Compared with aspirin, clopidogrel has marginal additional efficacy and similar safety, but carries a substantial price premium. It remains unclear whether its use is cost-effective. AIMS:(i...

journal_title：Internal medicine journal

authors： Kubler PA,Pillans PI,Marrinan MC,Frogley M

更新日期：2004-12-01 00:00:00

abstract：:Diabetes mellitus (DM) has been found to be associated with cardiovascular disease. The goal of this study is to evaluate the prevalence of asthma in patients with type II DM after adjusting for other comorbid conditions. We used patient treatment files of inpatients' admissions containing discharge diagnosis (Classif...

journal_title：Internal medicine journal

authors： Hashemzadeh M,Movahed MR

更新日期：2009-10-01 00:00:00

abstract：AIM:Premature discontinuation of antiplatelet therapy is an independent predictor of late stent thrombosis. We sought to determine the prevalence and predictors of premature discontinuation of antiplatelet therapy after drug-eluting stent implantation among patients in Asia. METHODS:A total of 207 consecutive patients...

journal_title：Internal medicine journal

authors： Poh CL,Chan MY,Lau C,Teo SG,Low AF,Tan HC,Lee CH

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:The reported risk of depression in patients with hypomagnesaemia is controversial. AIM:The objective of this meta-analysis was to assess the association between depression and hypomagnesaemia. METHODS:A literature search was performed using MEDLINE, EMBASE, Cochrane Database and clinicaltrials.gov from inc...

journal_title：Internal medicine journal

authors： Cheungpasitporn W,Thongprayoon C,Mao MA,Srivali N,Ungprasert P,Varothai N,Sanguankeo A,Kittanamongkolchai W,Erickson SB

更新日期：2015-04-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) has been described as a cause of thrombotic microangiopathy, especially thrombotic thrombocytopenic purpura (TTP). Haemolytic-uraemic syndrome (HUS) is less frequent in SLE. We report a case of such an association during an episode of severe lupus nephritis in a young woman, who was ...

journal_title：Internal medicine journal

authors： Samson M,Audia S,Leguy V,Berthier S,Janikashvili N,Martin L,Bonnotte B,Lorcerie B

更新日期：2012-01-01 00:00:00

abstract：:The Australian Clinical Guidelines for Stroke Management 2010 represents an update of the Clinical Guidelines for Stroke Rehabilitation and Recovery (2005) and the Clinical Guidelines for Acute Stroke Management (2007). For the first time, they cover the whole spectrum of stroke, from public awareness and prehospital ...

journal_title：Internal medicine journal

authors： Wright L,Hill KM,Bernhardt J,Lindley R,Ada L,Bajorek BV,Barber PA,Beer C,Golledge J,Gustafsson L,Hersh D,Kenardy J,Perry L,Middleton S,Brauer SG,Nelson MR,National Stroke Foundation Stroke Guidelines Expert Working Group.

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Populations with increased skin pigmentation who have migrated to countries of high latitude are at increased risk of low vitamin D. This study aimed to determine the prevalence of low vitamin D among the refugee population arriving in New Zealand. METHODS:An audit of all refugees arriving at the national r...

journal_title：Internal medicine journal

authors： Wishart HD,Reeve AM,Grant CC

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Early involvement of palliative care and advance care planning improves quality of life outcomes and survival for patients with advanced lung cancer, however there are barriers to implementation. AIMS AND METHODS:A single-centre prospective audit reviewing "Goals of Care" (GOC) form completion and palliativ...

journal_title：Internal medicine journal

authors： Conduit C,Thompson M,Thomas R,Nott L,Wuttke M

更新日期：2020-03-23 00:00:00

abstract：BACKGROUND:Haemolysis, elevated liver enzymes and low platelets (HELLP) syndrome occurs in one to six per 1000 pregnancies; maternal death has been reported in 1-24% of cases. Vague presentation is common; hypertension and proteinuria which characterise pre eclampsia are often absent when HELLP syndrome presents. Physi...

journal_title：Internal medicine journal

authors： Jayawardena L,Mcnamara E

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Exacerbations requiring hospital admission for chronic obstructive pulmonary disease (COPD) contribute to a decline in health status and are costly to the community. Long-term trends in admissions and associated outcomes are difficult to establish because of frequent readmissions, high case fatality and pote...

journal_title：Internal medicine journal

authors： Geelhoed EA,Brameld KJ,Holman CD,Thompson PJ

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:IgE-mediated allergy to the wheat protein omega-5-gliadin (O5G) is associated with wheat-dependent exercise-induced anaphylaxis (WDEIA), where exercise acts as a cofactor, triggering anaphylaxis after wheat ingestion. The wider application of O5G-specific IgE (sIgE) testing has revealed that the manifestatio...

journal_title：Internal medicine journal

authors： Le TA,Al Kindi M,Tan JA,Smith A,Heddle RJ,Kette FE,Hissaria P,Smith WB

更新日期：2016-06-01 00:00:00

abstract：:(Neo)adjuvant chemotherapy for early stage breast cancer is associated with side-effects, resulting in increased emergency department (ED) presentations. Treatment-related toxicity can affect quality of life, compromise chemotherapy delivery and treatment outcomes, and increase healthcare use. We performed a retrospec...

journal_title：Internal medicine journal

authors： Tang M,Horsley P,Lewis CR

更新日期：2018-05-01 00:00:00

abstract：:The negative health effects of the 2003 invasion of Iraq should act as a watershed in the medical profession's approach to violent conflict. ...

journal_title：Internal medicine journal

authors： Huggan PJ

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:The parenteral administration of oestradiol acutely protects against exercise-induced myocardial ischaemia in women, but whether this effect is sex-specific is not known. AIMS:The effects of acutely administered conjugated equine oestrogen on exercise-induced myocardial ischaemia in men with established cor...

journal_title：Internal medicine journal

authors： Davis SR,Bradbury J,Bell R,Johns JA

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Anticipating the prospect of specific treatment, we studied a large group of Australians with Fabry's disease. AIMS:We aimed to: (i) document the clinical features of Fabry's disease in Australian patients, (ii) test the hypothesis that clinical features vary with specific mutation and blood group and (iii)...

journal_title：Internal medicine journal

authors： Galanos J,Nicholls K,Grigg L,Kiers L,Crawford A,Becker G

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:The short Synacthen test is widely used to assess the hypothalamus pituitary adrenal axis in the outpatient setting. In the inpatient setting however, technical difficulties to adhere to the protocol may pose a challenge for using this test. AIMS:In this study we attempted to find the most suitable basal se...

journal_title：Internal medicine journal

authors： Tolkin L,Vidberg M,Munter G

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:There is no mechanism in place for monitoring or quality improvement of cancer multidisciplinary meetings (MDM) in Australia. AIM:To develop a peer-review process for quality improvement of MDM. METHODS:This project involved three phases: (i) development of a draft peer-review framework, supporting documen...

journal_title：Internal medicine journal

authors： Johnson CE,Slavova-Azmanova N,Saunders C

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Low dose computed tomography (LDCT) screening can reduce lung cancer deaths in high risk individuals yet current Australian guidelines do not recommend screening. Little is known about current screening practices in Australia. METHODS:A survey was distributed to a nationally-representative sample of 4000 Au...

journal_title：Internal medicine journal

authors： Abeyweera PD,Brims FJH,Piccolo F,Lei C,Manners D

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Off-label use of rituximab in lupus nephritis is reported to be beneficial. While the optimal dose is unknown, the regimen of four intravenous doses of 375 mg/m(2) is commonly employed, despite expense and potential side-effects. AIM:To investigate the response to single-dose rituximab, added to standard co...

journal_title：Internal medicine journal

authors： Kotagiri P,Martin A,Hughes P,Becker G,Nicholls K

更新日期：2016-08-01 00:00:00

abstract：:The use of tissue-type plasminogen activator (t-PA) in ischaemic stroke outside of experienced stroke centres remains controversial. The aim of this study was to present the initial experience with t-PA in patients with ischaemic stroke at an institution with no prior experience in i.v. stroke thrombolysis and to comp...

journal_title：Internal medicine journal

authors： Bray JE,Coughlan K,Bladin C

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Quick Sepsis-related Organ Failure Assessment (qSOFA) is recommended for use by the most recent international sepsis definition taskforce to identify suspected sepsis in patients outside the Intensive Care Unit (ICU) at risk of adverse outcomes. Evidence of its comparative effectiveness with existing sepsis ...

journal_title：Internal medicine journal

authors： Li L,Rathnayake K,Green M,Shetty A,Fullick M,Walter S,Middleton-Rennie C,Meller M,Braithwaite J,Lander H,Westbrook JI

更新日期：2020-01-06 00:00:00

abstract：:The burden and consequences of skin infections for remote living indigenous people are high. While skin infections are recognised as an antecedent to conditions such as acute rheumatic fever in children, data are limited concerning skin infection complications such as cellulitis, abscesses and osteomyelitis in older c...

journal_title：Internal medicine journal

authors： Thomas L,Bowen AC,Tong SYC

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Myelodysplastic syndrome (MDS), a haematological disorder of the elderly, has been formally classified as a neoplastic disease for 10 years. AIMS:Our aim was to collate national cancer registry incidence data to describe the epidemiology of MDS in New Zealand. METHODS:The New Zealand Cancer Registry has no...

journal_title：Internal medicine journal

authors： Rodger EJ,Morison IM

更新日期：2012-11-01 00:00:00

abstract：:Previous reports have noted an association between membranous nephropathy and focal segmental glomerulosclerosis with Guillain-Barre syndrome. We report a case of Campylobacter enteritis, which was complicated by both focal segmental glomerulosclerosis of the collapsing variety and Guillain-Barre syndrome, and propose...

journal_title：Internal medicine journal

authors： Lim A,Lydia A,Rim H,Dowling J,Kerr P

更新日期：2007-10-01 00:00:00