Author Correction: Reactive oxygen species induce antibiotic tolerance during systemic Staphylococcus aureus infection.


:An amendment to this paper has been published and can be accessed via a link at the top of the paper.


Nat Microbiol


Nature microbiology


Rowe SE,Wagner NJ,Li L,Beam JE,Wilkinson AD,Radlinski LC,Zhang Q,Miao EA,Conlon BP




Has Abstract


2020-03-01 00:00:00












  • Genome reduction in an abundant and ubiquitous soil bacterium 'Candidatus Udaeobacter copiosus'.

    abstract::Although bacteria within the Verrucomicrobia phylum are pervasive in soils around the world, they are under-represented in both isolate collections and genomic databases. Here, we describe a single verrucomicrobial group within the class Spartobacteria that is not closely related to any previously described taxa. We e...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Brewer TE,Handley KM,Carini P,Gilbert JA,Fierer N

    更新日期:2016-10-31 00:00:00

  • Environmental drivers of a microbial genomic transition zone in the ocean's interior.

    abstract::The core properties of microbial genomes, including GC content and genome size, are known to vary widely among different bacteria and archaea 1,2 . Several hypotheses have been proposed to explain this genomic variability, but the fundamental drivers that shape bacterial and archaeal genomic properties remain uncertai...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Mende DR,Bryant JA,Aylward FO,Eppley JM,Nielsen T,Karl DM,DeLong EF

    更新日期:2017-10-01 00:00:00

  • The intestinal regionalization of acute norovirus infection is regulated by the microbiota via bile acid-mediated priming of type III interferon.

    abstract::Evidence has accumulated to demonstrate that the intestinal microbiota enhances mammalian enteric virus infections1. For example, we and others previously reported that commensal bacteria stimulate acute and persistent murine norovirus infections2-4. However, in apparent contradiction of these results, the virulence o...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Grau KR,Zhu S,Peterson ST,Helm EW,Philip D,Phillips M,Hernandez A,Turula H,Frasse P,Graziano VR,Wilen CB,Wobus CE,Baldridge MT,Karst SM

    更新日期:2020-01-01 00:00:00

  • Plasmid-encoded tet(X) genes that confer high-level tigecycline resistance in Escherichia coli.

    abstract::Tigecycline is one of the last-resort antibiotics to treat complicated infections caused by both multidrug-resistant Gram-negative and Gram-positive bacteria1. Tigecycline resistance has sporadically occurred in recent years, primarily due to chromosome-encoding mechanisms, such as overexpression of efflux pumps and r...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Sun J,Chen C,Cui CY,Zhang Y,Liu X,Cui ZH,Ma XY,Feng Y,Fang LX,Lian XL,Zhang RM,Tang YZ,Zhang KX,Liu HM,Zhuang ZH,Zhou SD,Lv JN,Du H,Huang B,Yu FY,Mathema B,Kreiswirth BN,Liao XP,Chen L,Liu YH

    更新日期:2019-09-01 00:00:00

  • Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation.

    abstract::Retinoic acid-inducible gene I (RIG-I) receptor recognizes 5'-triphosphorylated RNA and triggers a signalling cascade that results in the induction of type-I interferon (IFN)-dependent responses. Its precise regulation represents a pivotal balance between antiviral defences and autoimmunity. To elucidate the cellular ...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Soonthornvacharin S,Rodriguez-Frandsen A,Zhou Y,Galvez F,Huffmaster NJ,Tripathi S,Balasubramaniam VR,Inoue A,de Castro E,Moulton H,Stein DA,Sánchez-Aparicio MT,De Jesus PD,Nguyen Q,König R,Krogan NJ,García-Sastre A,Yoh

    更新日期:2017-03-01 00:00:00

  • Species-function relationships shape ecological properties of the human gut microbiome.

    abstract::Despite recent progress, the organization and ecological properties of the intestinal microbial ecosystem remain under-investigated. Here, using a manually curated metabolic module framework for (meta-)genomic data analysis, we studied species-function relationships in gut microbial genomes and microbiomes. Half of gu...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Vieira-Silva S,Falony G,Darzi Y,Lima-Mendez G,Garcia Yunta R,Okuda S,Vandeputte D,Valles-Colomer M,Hildebrand F,Chaffron S,Raes J

    更新日期:2016-06-13 00:00:00

  • Co-occurring genomic capacity for anaerobic methane and dissimilatory sulfur metabolisms discovered in the Korarchaeota.

    abstract::Phylogenetic and geological evidence supports the hypothesis that life on Earth originated in thermal environments and conserved energy through methanogenesis or sulfur reduction. Here we describe two populations of the deeply rooted archaeal phylum Korarchaeota, which were retrieved from the metagenome of a circumneu...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: McKay LJ,Dlakić M,Fields MW,Delmont TO,Eren AM,Jay ZJ,Klingelsmith KB,Rusch DB,Inskeep WP

    更新日期:2019-04-01 00:00:00

  • Murine colitis reveals a disease-associated bacteriophage community.

    abstract::The dysregulation of intestinal microbial communities is associated with inflammatory bowel diseases (IBD). Studies aimed at understanding the contribution of the microbiota to inflammatory diseases have primarily focused on bacteria, yet the intestine harbours a viral component dominated by prokaryotic viruses known ...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Duerkop BA,Kleiner M,Paez-Espino D,Zhu W,Bushnell B,Hassell B,Winter SE,Kyrpides NC,Hooper LV

    更新日期:2018-09-01 00:00:00

  • Erratum: Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.

    abstract::This corrects the article DOI: 10.1038/nmicrobiol.2016.155. ...

    journal_title:Nature microbiology

    pub_type: 已发布勘误


    authors: Buffalo CZ,Bahn-Suh AJ,Hirakis SP,Biswas T,Amaro RE,Nizet V,Ghosh P

    更新日期:2017-06-12 00:00:00

  • Bacterial alginate regulators and phage homologs repress CRISPR-Cas immunity.

    abstract::CRISPR-Cas systems are adaptive immune systems that protect bacteria from bacteriophage (phage) infection1. To provide immunity, RNA-guided protein surveillance complexes recognize foreign nucleic acids, triggering their destruction by Cas nucleases2. While the essential requirements for immune activity are well under...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Borges AL,Castro B,Govindarajan S,Solvik T,Escalante V,Bondy-Denomy J

    更新日期:2020-05-01 00:00:00

  • Phosphatidic acid governs natural egress in Toxoplasma gondii via a guanylate cyclase receptor platform.

    abstract::Toxoplasma gondii establishes a lifelong chronic infection in humans and animals1. Host cell entry and egress are key steps in the lytic cycle of this obligate intracellular parasite, ensuring its survival and dissemination. Egress is temporally orchestrated, underpinned by the exocytosis of secretory organelles calle...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Bisio H,Lunghi M,Brochet M,Soldati-Favre D

    更新日期:2019-03-01 00:00:00

  • Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis.

    abstract::Primary sclerosing cholangitis (PSC) is a chronic inflammatory liver disease and its frequent complication with ulcerative colitis highlights the pathogenic role of epithelial barrier dysfunction. Intestinal barrier dysfunction has been implicated in the pathogenesis of PSC, yet its underlying mechanism remains unknow...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Nakamoto N,Sasaki N,Aoki R,Miyamoto K,Suda W,Teratani T,Suzuki T,Koda Y,Chu PS,Taniki N,Yamaguchi A,Kanamori M,Kamada N,Hattori M,Ashida H,Sakamoto M,Atarashi K,Narushima S,Yoshimura A,Honda K,Sato T,Kanai T

    更新日期:2019-03-01 00:00:00

  • Publisher Correction: Enterotypes in the landscape of gut microbial community composition.

    abstract::In the version of this Perspective originally published, the first and last name of co-author Manimozhiyan Arumugam were switched. This has now been corrected in all versions of the Perspective. ...

    journal_title:Nature microbiology

    pub_type: 已发布勘误


    authors: Costea PI,Hildebrand F,Arumugam M,Bäckhed F,Blaser MJ,Bushman FD,de Vos WM,Ehrlich SD,Fraser CM,Hattori M,Huttenhower C,Jeffery IB,Knights D,Lewis JD,Ley RE,Ochman H,O'Toole PW,Quince C,Relman DA,Shanahan F,Sunaga

    更新日期:2018-03-01 00:00:00

  • Monkeypox virus emergence in wild chimpanzees reveals distinct clinical outcomes and viral diversity.

    abstract::Monkeypox is a viral zoonotic disease on the rise across endemic habitats. Despite the growing importance of monkeypox virus, our knowledge on its host spectrum and sylvatic maintenance is limited. Here, we describe the recent repeated emergence of monkeypox virus in a wild, human-habituated western chimpanzee (Pan tr...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Patrono LV,Pléh K,Samuni L,Ulrich M,Röthemeier C,Sachse A,Muschter S,Nitsche A,Couacy-Hymann E,Boesch C,Wittig RM,Calvignac-Spencer S,Leendertz FH

    更新日期:2020-07-01 00:00:00

  • Chance and pleiotropy dominate genetic diversity in complex bacterial environments.

    abstract::How does environmental complexity affect the evolution of single genes? Here, we measured the effects of a set of Bacillus subtilis glutamate dehydrogenase mutants across 19 different environments-from phenotypically homogeneous single-cell populations in liquid media to heterogeneous biofilms, plant roots and soil po...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Noda-García L,Davidi D,Korenblum E,Elazar A,Putintseva E,Aharoni A,Tawfik DS

    更新日期:2019-07-01 00:00:00

  • Growth control switch by a DNA-damage-inducible toxin-antitoxin system in Caulobacter crescentus.

    abstract::Bacterial toxin-antitoxin systems (TASs) are thought to respond to various stresses, often inducing growth-arrested (persistent) sub-populations of cells whose housekeeping functions are inhibited. Many such TASs induce this effect through the translation-dependent RNA cleavage (RNase) activity of their toxins, which ...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Kirkpatrick CL,Martins D,Redder P,Frandi A,Mignolet J,Chapalay JB,Chambon M,Turcatti G,Viollier PH

    更新日期:2016-02-22 00:00:00

  • Immune priming and clearance of orally acquired RNA viruses in Drosophila.

    abstract::Immune responses in insects are differentially triggered depending on the infection route used by the pathogen. In most studies involving Drosophila melanogaster and viruses, infection is done by injection, while oral infection, which is probably the most common route of viral entry in nature, remains unexplored. Here...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Mondotte JA,Gausson V,Frangeul L,Blanc H,Lambrechts L,Saleh MC

    更新日期:2018-12-01 00:00:00

  • Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB.

    abstract::The IncC family of broad-host-range plasmids enables the spread of antibiotic resistance genes among human enteric pathogens1-3. Although aspects of IncC plasmid conjugation have been well studied4-9, many roles of conjugation genes have been assigned based solely on sequence similarity. We applied hypersaturated tran...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Hancock SJ,Phan MD,Luo Z,Lo AW,Peters KM,Nhu NTK,Forde BM,Whitfield J,Yang J,Strugnell RA,Paterson DL,Walsh TR,Kobe B,Beatson SA,Schembri MA

    更新日期:2020-11-01 00:00:00

  • Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform.

    abstract::The development of new drug regimens that allow rapid, sterilizing treatment of tuberculosis has been limited by the complexity and time required for genetic manipulations in Mycobacterium tuberculosis. CRISPR interference (CRISPRi) promises to be a robust, easily engineered and scalable platform for regulated gene si...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Rock JM,Hopkins FF,Chavez A,Diallo M,Chase MR,Gerrick ER,Pritchard JR,Church GM,Rubin EJ,Sassetti CM,Schnappinger D,Fortune SM

    更新日期:2017-02-06 00:00:00

  • Lactate signalling regulates fungal β-glucan masking and immune evasion.

    abstract::As they proliferate, fungi expose antigens at their cell surface that are potent stimulators of the innate immune response, and yet the commensal fungus Candida albicans is able to colonize immuno competent individuals. We show that C. albicans may evade immune detection by presenting a moving immunological target. We...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Ballou ER,Avelar GM,Childers DS,Mackie J,Bain JM,Wagener J,Kastora SL,Panea MD,Hardison SE,Walker LA,Erwig LP,Munro CA,Gow NA,Brown GD,MacCallum DM,Brown AJ

    更新日期:2016-12-12 00:00:00

  • Author Correction: Evolution of host adaptation in the Salmonella typhoid toxin.

    abstract::The original version of this Letter has been modified in the abstract and main text to better reflect the distribution of Neu5Ac sialoglycans in humans. Additionally, co-author Lingquan Deng's present address has been further clarified. ...

    journal_title:Nature microbiology

    pub_type: 已发布勘误


    authors: Gao X,Deng L,Stack G,Yu H,Chen X,Naito-Matsui Y,Varki A,Galán JE

    更新日期:2017-12-01 00:00:00

  • Phenotypic heterogeneity driven by nutrient limitation promotes growth in fluctuating environments.

    abstract::Most microorganisms live in environments where nutrients are limited and fluctuate over time. Cells respond to nutrient fluctuations by sensing and adapting their physiological state. Recent studies suggest phenotypic heterogeneity(1) in isogenic populations as an alternative strategy in fluctuating environments, wher...

    journal_title:Nature microbiology

    pub_type: 信件


    authors: Schreiber F,Littmann S,Lavik G,Escrig S,Meibom A,Kuypers MM,Ackermann M

    更新日期:2016-05-09 00:00:00

  • A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.

    abstract::Pathogenic bacteria are armed with potent effector proteins that subvert host signalling processes during infection1. The activities of bacterial effectors and their associated roles within the host cell are often poorly understood, particularly for Chlamydia trachomatis2, a World Health Organization designated neglec...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Pruneda JN,Bastidas RJ,Bertsoulaki E,Swatek KN,Santhanam B,Clague MJ,Valdivia RH,Urbé S,Komander D

    更新日期:2018-12-01 00:00:00

  • Excess of non-conservative amino acid changes in marine bacterioplankton lineages with reduced genomes.

    abstract::Surface ocean waters are dominated by planktonic bacterial lineages with highly reduced genomes. The best examples are the cyanobacterial genus Prochlorococcus, the alphaproteobacterial clade SAR11 and the gammaproteobacterial clade SAR86, which together represent over 50% of the cells in surface oceans. Several studi...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Luo H,Huang Y,Stepanauskas R,Tang J

    更新日期:2017-06-12 00:00:00

  • Global spread of three multidrug-resistant lineages of Staphylococcus epidermidis.

    abstract::Staphylococcus epidermidis is a conspicuous member of the human microbiome, widely present on healthy skin. Here we show that S. epidermidis has also evolved to become a formidable nosocomial pathogen. Using genomics, we reveal that three multidrug-resistant, hospital-adapted lineages of S. epidermidis (two ST2 and on...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Lee JYH,Monk IR,Gonçalves da Silva A,Seemann T,Chua KYL,Kearns A,Hill R,Woodford N,Bartels MD,Strommenger B,Laurent F,Dodémont M,Deplano A,Patel R,Larsen AR,Korman TM,Stinear TP,Howden BP

    更新日期:2018-10-01 00:00:00

  • Epstein-Barr virus ncRNA from a nasopharyngeal carcinoma induces an inflammatory response that promotes virus production.

    abstract::The Epstein-Barr virus M81 strain, isolated from a nasopharyngeal carcinoma, induces potent spontaneous virus production in infected B cells. We found that the M81 non-coding Epstein-Barr-encoded RNA EBER2, which carries polymorphisms that are mainly restricted to viruses found in endemic nasopharyngeal carcinomas, ma...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Li Z,Tsai MH,Shumilov A,Baccianti F,Tsao SW,Poirey R,Delecluse HJ

    更新日期:2019-12-01 00:00:00

  • Methods for phylogenetic analysis of microbiome data.

    abstract::How does knowing the evolutionary history of microorganisms affect our analysis of microbiological datasets? Depending on the research question, the common ancestry of microorganisms can be a source of confounding variation, or a scaffolding used for inference. For example, when performing regression on traits, common...

    journal_title:Nature microbiology

    pub_type: 杂志文章,评审


    authors: Washburne AD,Morton JT,Sanders J,McDonald D,Zhu Q,Oliverio AM,Knight R

    更新日期:2018-06-01 00:00:00

  • AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling.

    abstract::Zika virus (ZIKV) is associated with neonatal microcephaly and Guillain-Barré syndrome1,2. While progress has been made in understanding the causal link between ZIKV infection and microcephaly3-9, the life cycle and pathogenesis of ZIKV are less well understood. In particular, there are conflicting reports on the role...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Chen J,Yang YF,Yang Y,Zou P,Chen J,He Y,Shui SL,Cui YR,Bai R,Liang YJ,Hu Y,Jiang B,Lu L,Zhang X,Liu J,Xu J

    更新日期:2018-03-01 00:00:00

  • Broad-spectrum anti-CRISPR proteins facilitate horizontal gene transfer.

    abstract::CRISPR-Cas adaptive immune systems protect bacteria and archaea against their invading genetic parasites, including bacteriophages/viruses and plasmids. In response to this immunity, many phages have anti-CRISPR (Acr) proteins that inhibit CRISPR-Cas targeting. To date, anti-CRISPR genes have primarily been discovered...

    journal_title:Nature microbiology

    pub_type: 杂志文章


    authors: Mahendra C,Christie KA,Osuna BA,Pinilla-Redondo R,Kleinstiver BP,Bondy-Denomy J

    更新日期:2020-04-01 00:00:00

  • Mini viral RNAs act as innate immune agonists during influenza virus infection.

    abstract::The molecular processes that determine the outcome of influenza virus infection in humans are multifactorial and involve a complex interplay between host, viral and bacterial factors1. However, it is generally accepted that a strong innate immune dysregulation known as 'cytokine storm' contributes to the pathology of ...

    journal_title:Nature microbiology

    pub_type: 信件


    authors: Te Velthuis AJW,Long JC,Bauer DLV,Fan RLY,Yen HL,Sharps J,Siegers JY,Killip MJ,French H,Oliva-Martín MJ,Randall RE,de Wit E,van Riel D,Poon LLM,Fodor E

    更新日期:2018-11-01 00:00:00