Abstract:
:BACKGROUND Laparoscopic donor nephrectomy (LDN) has evolved and has been established as a surgical standard of care for kidney transplantation. MATERIAL AND METHODS This study retrospectively reviews 1132 patients who underwent 4 different laparoscopic living-donor nephrectomies: hand-assisted laparoscopic nephrectomy (HALDN), pure laparoscopic donor nephrectomy (PLDN), laparoendoscopic single-site plus 1-port donor nephrectomy (LESSOP-DN), and mini laparoscopic donor nephrectomy (MLDN). RESULTS The mean estimated blood loss (EBL) for the HALDN group was meaningfully higher than those of LESSOP-DN and MLDN (57.5±52.2 mL versus 21.0±30.0 mL versus 18.2±28.7 mL) (P<0.001). The EBL for PLDN (53.3±35.3 mL) was also significantly higher than those of LESSOP-DN and MLDN (P<0.001). Length of stay (LOS) for HALDN was longer than that for LESSOP-DN (4.2±1.2 day versus 4.0±1.4 days, P=0.002). There was 1 intraoperative open conversion in the HALDN group and 2 HALDN surgeries that required postoperative exploratory laparotomy. LESSOP-DN had 3 (0.8%) postoperative incisional hernias. For recipients, the results revealed no significant differences between all 4 groups in terms of estimated glomerular filtration rate (eGFR) and the 1-year graft failure rate. CONCLUSIONS The LESSOP-DN group was associated with a shorter incision length than those of HALDN and PLDN and shorter LOS than that of HALDN. Recipient results showed no meaningful difference regarding laparoscopic donor nephrectomy technique.
journal_name
Ann Transplantjournal_title
Annals of transplantationauthors
Cho SJ,Moon HW,Kang SM,Choi SW,Kim KS,Choi YS,Hong SH,Ha US,Lee JY,Kim SW,Kim JC,Cho HJdoi
10.12659/AOT.918189subject
Has Abstractpub_date
2020-02-11 00:00:00pages
e918189eissn
1425-9524issn
2329-0358pii
918189journal_volume
25pub_type
杂志文章abstract:BACKGROUND:Transplantation is the only effective method of treatment for end-stage and acute liver failure. Increased average survival time has been observed, and results from improved surgical technique and amended immunosuppression protocols. However, longer survival of patients after orthotopic liver transplantation...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.882005
更新日期:2011-07-01 00:00:00
abstract::Advances in molecular biology techniques allowed for introduction of PCR-based methods for HLA typing. In routine HLA typing for organ transplantation serological method is still being used as a standard, although molecular techniques are applied more and more often. The aim of our study was to compare HLA-DR typing u...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::For each individual, there is a limit to the capacity to perform exercise. The limitation, however, depends on the nature of the task and is also influenced by a number of other factors. Muscle strength is determined largely by muscle mass, specifically muscle cross-sectional area, but is also influenced by neural dri...
journal_title:Annals of transplantation
pub_type: 杂志文章,评审
doi:
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Renal dysfunction often occurs in liver transplant (LT) recipients receiving calcineurin inhibitor (CNI)-based immunosuppressive regimens, increasing morbidity and mortality rates. Replacement of CNIs by mTOR inhibitor-based immunosuppressive protocols may prevent renal impairment in LT recipients. MATERIAL...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.895320
更新日期:2015-11-26 00:00:00
abstract::Liver graft function after transplantation is dependent on ischemia-reperfusion injury, toxicity of drugs (immunosuppression, antibiotics and other) and transplant rejection. Although routinely monitored with enzymatic tests (AST, ALT, GGT, ALP), bilirubin and coagulation parameters, differentiation between these path...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::BACKGROUND Inflammatory activity of the artery can be assessed by measuring 18F-fluorodeoxyglucose (18F-FDG) uptake with positron emission tomography computed tomography (PET/CT). Improvement in vascular function after renal transplantation has been reported, but no studies have used 18F-FDG PET/CT to examine the chan...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.909212
更新日期:2018-06-15 00:00:00
abstract:BACKGROUND:Induction of the hepatic and intestinal cytochrome P450-3A4 system and intestinal P-glycoprotein is an unavoidable consequence of rifampin administration which requires substantial increase in tacrolimus dose when given concurrently. Chronic diarrhea is known to precipitate tacrolimus toxicity irrespective o...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::Rat pancreatic islets were immunoisolated within alginate capsules with additional polyethyleneimine-protamine-heparin highly biocompatible membrane. Perifusion study in vitro demonstrated satisfactory similarities between the insulin release profiles of encapsulated and free islets. Concordant xenotransplantation of ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Antibody-mediated rejection (AMR), associated with the presence of C4d deposits, is well-defined in kidney transplantation but much less documented in liver transplantation (LTx). The aim of our study was to retrospectively analyze a group of pediatric liver transplant recipients who experienced episodes of ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.889921
更新日期:2014-03-04 00:00:00
abstract:BACKGROUND:Metabolic abnormalities have been reported in patients undergoing hematopoietic stem cell transplantation (HSCT). Potential causes, risk factors and outcomes of electrolyte imbalances have thoroughly been investigated. On HSCT recipients, multiple pathophysiologic contributors are inflicting electrolyte abno...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:Early post-operative hyperglycemia is commonly encountered in patients without pre-existing diabetes mellitus who are undergoing kidney transplantation. The aim of this study was to determine the effect of early post-operative hyperglycemia on graft and patient survival after kidney transplantation in our ce...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.883937
更新日期:2013-06-07 00:00:00
abstract::Organ transplantation program has been slowly developing over last 30 years. The number of DD (deceased donors) stabilized on the level of approximately 13/million of population. Multiorgan donation has been 45%, due to some problems with donor management. Polish Transplant Coordinating Center POLTRANSPLANT which is r...
journal_title:Annals of transplantation
pub_type: 社论
doi:
更新日期:2007-01-01 00:00:00
abstract::The ability of kidney transplantation to improve quality of life has made this therapeutic modality the treatment of choice among renal replacement therapies; however, the continuing organ shortage has forced the use of marginal kidneys as a supplementary source of allografts. It has been repeatedly suggested that fai...
journal_title:Annals of transplantation
pub_type: 杂志文章,评审
doi:10.12659/aot.898405
更新日期:2016-07-26 00:00:00
abstract::BACKGROUND Organ transplantation is one of the most critical topics in medical ethics that is commonplace in various countries. This study aimed to evaluate the knowledge and the ethical issues surrounding organ transplantation and organ donation among healthcare personnel in Tehran, Iran. MATERIAL AND METHODS In a cr...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.908615
更新日期:2018-05-04 00:00:00
abstract::Aim of this monocentric study is to compare the outcome of 101 renal transplants performed in patients older than 55 years with single kidney retrieved from donors older than 50 years, with 263 transplants performed in patients younger than 55 years transplanted with young kidneys. Delayed graft function (DGF) had sim...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Colonic diverticular disease is rare in developing nations but common in Western and industrialized societies. Many studies show that heart and lung transplantation increase the risk of having severe diverticulitis, although the exact magnitude of this risk remain unclear because many of these studies have b...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2010-07-01 00:00:00
abstract::Complete situs inversus (SI) is a very rare anomaly characterized by the total inversion of all abdominal and thoracic organs. SI has been traditionally considered an absolute contraindication for liver and heart transplantation. We report a case of a donor with complete SI diagnosed at the time of organ recovery and ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::This paper outlines the effect that the Transplant Games have had in influencing public opinion and the translation of that effect resulting in increased organ donation and transplantation in the global venues in which this activity took place. A brief account of the history of the Transplant Games now 25 years after ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::The patient is a 28 year old woman who received a heart transplant in 1992 secondary to hypertrophic cardiomyopathy with unremarkable post-operative course. In the period immediately post transplantation the patient was on a four-drug immunosuppressive regimen which was subsequently changed to standard three-agent the...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVES:The goal of this study was to examine the impact of various immunosuppressive regimens on an early NK cell recovery following haematopoietic cell transplantation (alloHCT). METHODS:The number of peripheral blood NK cells was analysed with the use of flow cytometry on day +30 (+/-2) after alloHCT from an HLA...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVES:Aim of the study was to assess frequency and risk factors of steroid resistant cellular rejection (SRR) in heart transplant recipients, to determine methods of its treatment, and to evaluate influence of steroid resistant rejection and method of its treatment on short- and long-term results. METHODS:All pts...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::Solid organ transplantation program in Poland is very limited. The main reason of this is organ shortage. All the organs procured are transplanted. It is a general feeling that recently issued legal regulations will favorably influence organ donation, however the improvement may be expected within a few years and will...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::BACKGROUND TruGraf is a blood-based biomarker test that measures differential expression of a collection of genes that have been shown to correlate with surveillance biopsy results. However, in the majority of U.S. transplant centers, surveillance biopsies are not performed. The objectives of this study were to evalua...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.920839
更新日期:2020-04-28 00:00:00
abstract::The hepatitis B virus (HBV) infects more than 260 million people globally, with increasing incidence, especially in developing countries. Despite antiviral therapies, HBV-related end-stage liver disease remains one of the most important indications for liver transplantation worldwide. Although new available treatments...
journal_title:Annals of transplantation
pub_type: 杂志文章,评审
doi:10.12659/aot.900216
更新日期:2016-10-14 00:00:00
abstract:BACKGROUND:The results of pancreas transplantation depend in a large degree on appropriate pancreas allograft donor selection. Several risk factors of early surgical complications or pancreas allograft loss following transplantation have been identified, but the final decision on pancreas harvesting for transplantation...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.894464
更新日期:2015-11-03 00:00:00
abstract:BACKGROUND:Transplant renal artery stenosis (TRAS) is a serious vascular complication due to non-specific clinical manifestations, causing serious diagnostic difficulties. Contrast-enhanced ultrasound (CE-US) can complement standard sonographic examination in evaluation of TRAS. MATERIAL AND METHODS:Standard ultrasoun...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.883896
更新日期:2013-04-26 00:00:00
abstract::Over the last decade significant improvement in patient and graft survival has been observed after liver transplantation for hepatitis B virus (HBV)-related liver disease, mostly because of efficient prophylaxis against hepatitis B reinfection. This review discusses different approches in prevention of hepatitis B rec...
journal_title:Annals of transplantation
pub_type: 杂志文章,评审
doi:
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Despite documented positive effect of MachinePerfusion (MP) on long-term kidneys-graft function its wide use is restricted due to higher costs. The aim of this study was to analyze the difference in costs of kidney transplantation in patients who received organ stored in ColdStorage (CS) vs those who receive...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2009-04-01 00:00:00
abstract::BACKGROUND ABO-incompatible (ABO-i) living donor liver transplantation (LDLT) is a feasible alternative for donor liver allograft in emergency situations, especially in Asia, where deceased-donor organs remain scarce. The reported outcomes of ABO-i LDLT after optimal desensitization are comparable to those of ABO-comp...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.923502
更新日期:2020-09-18 00:00:00
abstract:OBJECTIVES:Modification of the total body irradiation technique before bone marrow transplantation has been implemented to improve uniformity of the dose inside the irradiated body and to obtain appropriate reduction in doses in critical organs. METHODS:The total dose of 12.6 Gy was delivered with the use of a combina...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00