Post-marketing surveillance of adverse events following measles, mumps, rubella and varicella (MMRV) vaccine: retrospecive study in apulia region (ITALY), 2009-2017.

abstract：AIM:Pertussis continues to be a common worldwide infection in pediatric and adult populations. We aimed to study epidemiological and clinical characteristics of infants and children admitted for pertussis to a tertiary-care hospital and to investigate the risk factors for pediatric intensive care unit (PICU) admission....

journal_title：Human vaccines & immunotherapeutics

authors： Di Camillo C,Vittucci AC,Antilici L,Ciarlitto C,Linardos G,Concato C,Lancella L,Villani A

更新日期：2020-08-05 00:00:00

abstract：:Meningococcal serogroup B (MenB) is the predominant cause of invasive meningococcal disease in the United States, with older adolescents and young adults attending college at increased risk. Notably, MenB caused all meningococcal disease outbreaks at US colleges between 2011 and 2018. MenB disease is vaccine-preventab...

journal_title：Human vaccines & immunotherapeutics

authors： McDaniel A,Dempsey A,Srivastava A

更新日期：2019-01-01 00:00:00

abstract：:Background: Rotavirus (RV) is worldwide an important cause of acute gastroenteritis (AGE) in infants and young children. There is no specific treatment for AGE caused by RV (RVGE) but since 2006 two safe and effective vaccines have been available. RV vaccination was included in the national immunization program (NIP) ...

journal_title：Human vaccines & immunotherapeutics

authors： Tafalla M,Gardovska D,Gopala K,Kozlovska L

更新日期：2019-01-01 00:00:00

abstract：:Rotavirus vaccines were licensed in Spain between late 2006 and early 2007. Rotavirus vaccination was recommended but not reimbursed by the Spanish National Health System. Significant coverage rates have been reached in Galicia, with an average of 47% since the period July 2007-June 2008. We aim to explore eventual va...

journal_title：Human vaccines & immunotherapeutics

authors： Martinón-Torres F,Martinón-Torres N,Bouzón Alejandro M,Redondo Collazo L,Pértega-Díaz S,Seoane-Pillado MT,Aboal Viñas J,San-Martín M

更新日期：2012-07-01 00:00:00

abstract：:Influenza vaccination is the most effective way of preventing influenza infections but its coverage is extremely low in China. Poor influenza vaccine effectiveness (VE) was reported in the 2014/15 season in some Northern Hemisphere countries with a predominance of H3N2 viruses belonging to the 3C.2a clade. However, th...

journal_title：Human vaccines & immunotherapeutics

authors： Ma C,Pan Y,Zhang L,Zhang Y,Wu S,Sun Y,Duan W,Zhang M,Wang Q,Yang P

更新日期：2017-10-03 00:00:00

abstract：:SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), is suspected to have been first contracted via animal-human interactions; it has further spread across the world by efficient human-to-human transmission. Recent reports of COVID-19 in companion animals (dogs and cats) and wild carnivores such as tigers hav...

journal_title：Human vaccines & immunotherapeutics

authors： Sharun K,Tiwari R,Patel SK,Karthik K,Iqbal Yatoo M,Malik YS,Singh KP,Panwar PK,Harapan H,Singh RK,Dhama K

更新日期：2020-12-01 00:00:00

abstract：:Background: To assess the knowledge and attitudes of middle school students toward vaccination, we measured their understanding of vaccine safety and effectiveness, expectations for communication with heath care providers, and their desired role in the vaccination decision-making process. Methods: A cross-sectional, s...

journal_title：Human vaccines & immunotherapeutics

authors： Herman R,McNutt LA,Mehta M,Salmon DA,Bednarczyk RA,Shaw J

更新日期：2019-01-01 00:00:00

abstract：:Assessing the beliefs and attitudes of Health Care Workers (HCW) to influenza and influenza vaccination can be useful in overcoming low compliance rates. The purpose of our study is to evaluate the opinion of HCW and students regarding influenza, influenza vaccine and the factors associated with vaccination compliance...

journal_title：Human vaccines & immunotherapeutics

authors： Bonaccorsi G,Lorini C,Santomauro F,Guarducci S,Pellegrino E,Puggelli F,Balli M,Bonanni P

更新日期：2013-12-01 00:00:00

abstract：:Timely vaccine supply is critical during influenza pandemics but is impeded by current virus-based manufacturing methods. The 2009 H1N1/2009pdm 'swine flu' pandemic reinforced the need for innovation in pandemic vaccine design. We report on insights gained during rapid development of a pandemic vaccine based on recomb...

journal_title：Human vaccines & immunotherapeutics

authors： Honda-Okubo Y,Rajapaksha H,Sajkov D,Gordon D,Cox MMJ,Petrovsky N

更新日期：2017-06-03 00:00:00

abstract：:Pregnant women are risk group for influenza infection. Results of new subunit vaccines application have not been studied enough. Prospective, randomized, open-label comparative study of subunit (Agrippal) and polymeric subunit (Grippol plus) vaccines. 42 pairs of mothers-infants were participated in the study. Protect...

journal_title：Human vaccines & immunotherapeutics

authors： Kostinov MP,Cherdantsev AP,Kuselman AI,Akhmatova NK,Kostinova AM,Deryabina EV,Demina EO,Kostinov AM

更新日期：2018-01-01 00:00:00

abstract：:Integrating additive or synergistic antitumor effects that focus on distinct elements of tumor biology are the most rational strategies for cancer treatment. Treatments for breast cancer have increased overall survival, but remain limited by lack of efficacy in a subset of breast cancer patients. The real challenge is...

journal_title：Human vaccines & immunotherapeutics

authors： Kieber-Emmons T,Monzavi-Karbassi B,Hutchins LF,Pennisi A,Makhoul I

更新日期：2017-02-01 00:00:00

abstract：:The Advisory Committee on Immunization Practices recommends administering diphtheria, tetanus and acellular pertussis (DTaP) vaccines to children at 2, 4, 6, 15-18 months, and 4-6 y of age; preferably with the same-brand vaccine for the whole series. We estimated age-appropriate DTaP dose completion and the proportion...

journal_title：Human vaccines & immunotherapeutics

authors： Masseria C,Buikema AR,Liu F,Krishnarajah G

更新日期：2015-01-01 00:00:00

abstract：:The interleukin 6 (IL6) family of proteins regulate important cellular processes and act through a variety of signaling pathways via a shared gp130 receptor. In the liver, there is a large body of evidence showing a protective and pro-regenerative role for IL6 cis and trans signaling. While a few studies suggest a pat...

journal_title：Human vaccines & immunotherapeutics

authors： Widjaja AA,Chothani SP,Cook SA

更新日期：2020-10-02 00:00:00

abstract：:Eight months after the mass immunization campaign of November 2015 against measles and rubella in the southeast of Iran, in order to evaluate the sero-immunity level of the people living in the mentioned region, a serosurvey study was performed. Using a multi-stage probability proportional to size cluster sampling, th...

journal_title：Human vaccines & immunotherapeutics

authors： Izadi S,Zahraei SM,Mokhtari-Azad T

更新日期：2018-06-03 00:00:00

abstract：:Influenza, caused by the influenza virus, is a contagious acute viral respiratory disease with a high incidence rate and wide and rapid spread. Influenza-related morbidity, mortality, and hospitalization rates remain high and are increasing continuously in high-risk groups, with a significant impact on human health an...

journal_title：Human vaccines & immunotherapeutics

authors： Gao D,Yang H,Deng B,Yin G,Song W,Zhang H,Li Y

更新日期：2016-10-02 00:00:00

abstract：:Individuals fail to elicit protective antibody after hepatitis B vaccination remain at risk for hepatitis B virus infection. Analysis of the transcriptome of peripheral blood mononuclear cells (PBMCs) is essential to elucidate the characteristics of gene expression in non-responders. In this study, we enrolled seven r...

journal_title：Human vaccines & immunotherapeutics

authors： Qiu S,He P,Fang X,Tong H,Lv J,Liu J,Zhang L,Zhai X,Wang L,Hu Z,Yu Y

更新日期：2018-07-03 00:00:00

abstract：:Previously, we have shown that DNA prime-protein boost is effective in eliciting neutralizing antibodies (NAb) against randomly selected HIV-1 isolates. Given the genetic diversity of HIV-1 viruses and the unique predominant subtypes in different geographic regions, it is critical to test the DNA prime-protein boost a...

journal_title：Human vaccines & immunotherapeutics

authors： Zhang M,Zhang L,Zhang C,Hong K,Shao Y,Huang Z,Wang S,Lu S

更新日期：2012-11-01 00:00:00

abstract：:Vaccine information of varying quality is available through many different sources. We describe the creation, release and utilization of ReadyVax, a new mobile smartphone app providing access to trustworthy, evidence-based vaccine information for a target audience of healthcare providers, pharmacists, and patients (in...

journal_title：Human vaccines & immunotherapeutics

authors： Bednarczyk RA,Frew PM,Salmon DA,Whitney E,Omer SB

更新日期：2017-05-04 00:00:00

abstract：:Cancer vaccines are designed to stimulate the body's immune system to kill tumor cells. To improve their immunogenicity, vaccine antigens must be combined with adjuvants which are able to stimulate the innate immunity and potentiate the adaptive immune response. In the last years a new generation of adjuvants mimickin...

journal_title：Human vaccines & immunotherapeutics

authors： Circelli L,Tornesello M,Buonaguro FM,Buonaguro L

更新日期：2017-08-03 00:00:00

abstract：:Tetanus is caused by a neurotoxin produced by Clostridium tetani (C. tetani), a spore-forming bacterium. Infection begins when tetanus spores are introduced into damaged tissue. Tetanus is characterized by muscle rigidity and painful muscle spasms caused by tetanus toxin's blockade of inhibitory neurons that normally ...

journal_title：Human vaccines & immunotherapeutics

authors： Verma R,Khanna P

更新日期：2012-10-01 00:00:00

abstract：:WHO defines adolescence age between 10 to 19 years. In India, there are 243 million adolescents which constitute 21 per cent of the total population. The global burden of disease in adolescents (2011) reports that the total number of disability adjusted life years (DALYs) worldwide among adolescents were 230 million w...

journal_title：Human vaccines & immunotherapeutics

authors： Verma R,Khanna P,Chawla S

更新日期：2015-01-01 00:00:00

abstract：:Development of live-attenuated human respiratory syncytial virus (HRSV) vaccines has proven to be difficult. Several vaccine candidates were found to be over-attenuated and displayed limited immunogenicity. Recently, we identified three synthetic cationic lipopeptides that enhanced paramyxovirus infections in vitro. T...

journal_title：Human vaccines & immunotherapeutics

authors： Tien Nguyen D,Boes J,van Amerongen G,van Remmerden Y,Yüksel S,Guichelaar T,Osterhaus AD,de Swart RL

更新日期：2013-12-01 00:00:00

abstract：:The 2014-2016 Ebola virus outbreak in West Africa led to advances in the development of vaccines against Ebola. This study examined factors associated with willingness to pay for an Ebola vaccine among a U.S. national sample during the recent Ebola outbreak. From April 30-May 8, 2015, a national survey was conducted u...

journal_title：Human vaccines & immunotherapeutics

authors： Painter JE,von Fricken ME,Viana de O Mesquita S,DiClemente RJ

更新日期：2018-07-03 00:00:00

abstract：:Although catch-up campaigns (CCs) at the introduction of pneumococcal conjugate vaccines (PCVs) may accelerate their impact, supply constraints may limit their benefit if the need for additional PCV doses results in introduction delay. We studied the impact of PCV13 introduction with and without CC in Nha Trang, Vietn...

journal_title：Human vaccines & immunotherapeutics

authors： Le Polain De Waroux O,Edmunds WJ,Takahashi K,Ariyoshi K,Mulholland EK,Goldblatt D,Choi YH,Anh DD,Yoshida LM,Flasche S

更新日期：2018-01-01 00:00:00

abstract：:Human papillomavirus (HPV) can cause genital warts and HPV-related cancer.People living with human immunodeficiency virus (HIV)are more symptomatic for HPV infections.Campos dos Goytacazes,a municipality of Rio de Janeiro,introduced the quadrivalent HPV vaccine (4vHPV)for HIV-positive women four years before initiatio...

journal_title：Human vaccines & immunotherapeutics

authors： Miguel Haddad Kury C,Santos KCDS,Carestiato FN,Rapozo G,Leandro CG,Fernandes LA,Silva PRT,Passos MRL,Cruz OG,Cavalcanti SMB

更新日期：2020-09-22 00:00:00

abstract：:Immunocompromising conditions increase the risk of invasive pneumococcal disease (IPD). Vaccine uptake in patients with these conditions may be low in part because of concerns about decreased immunogenicity and safety in these high-risk groups. We conducted a literature search to identify publications describing antib...

journal_title：Human vaccines & immunotherapeutics

authors： Chilson E,Scott DA,Schmoele-Thoma B,Watson W,Moran MM,Isturiz R

更新日期：2020-11-01 00:00:00

abstract：:Influenza can be potentially fatal to vulnerable populations, particularly those in the hospital. Canada's National Advisory Committee on Immunization recommends that health-care workers (HCW) be immunized against influenza partly to avoid infecting high-risk populations. However, influenza immunization rates among HC...

journal_title：Human vaccines & immunotherapeutics

authors： Di Castri AM,Halperin DM,McPherson CM,Nunn A,Farrar-Muir H,Kwong JC,Henry B

更新日期：2020-06-02 00:00:00

abstract：:HIV sequence diversity and the propensity of eliciting immunodominant responses targeting inessential variable regions are hurdles in the development of an effective AIDS vaccine. We developed a DNA vaccine comprising conserved elements (CE) of SIV p27Gag and HIV-1 Env and found that priming vaccination with CE DNA is...

journal_title：Human vaccines & immunotherapeutics

authors： Hu X,Lu Z,Valentin A,Rosati M,Broderick KE,Sardesai NY,Marx PA,Mullins JI,Pavlakis GN,Felber BK

更新日期：2018-01-01 00:00:00

abstract：:Despite the long-term efficacy and immune persistence observed following HBV vaccination of infants, the need for a booster dose following infant immunization continues to be deliberated. Evidence from HBV booster dose response studies and long-term immunization program reviews are the basis for the recommendation tha...

journal_title：Human vaccines & immunotherapeutics

authors： Osiowy C

更新日期：2018-01-01 00:00:00

abstract：:Vaccination directly protects vaccinated individuals, but it also has the potential for indirectly protecting the unvaccinated in a population (herd protection). Unintended negative consequences such as the re-manifestation of infection, mainly expressed as age shifts, result from vaccination programs as well. We disc...

journal_title：Human vaccines & immunotherapeutics

authors： Scarbrough Lefebvre CD,Terlinden A,Standaert B

更新日期：2015-01-01 00:00:00