Histological and immunocytochemical study of the endocrine pancreas of the lizard Podarcis hispanica Steindachner, 1870 (Lacertidae).


:The endocrine pancreas of the lizard Podarcis hispanica is described using light and electron microscopy. The endocrine pancreas of this reptile is located throughout the spleen side of the organ and consists of islet-like structures, small groups of two to five cells, and single scattered endocrine cells. The endocrine cells, including the islet-like structures, are not discrete units; on the contrary, they are intermingled with the endocrine component, both forming the glandular units. The endocrine islet-like structure shows a peculiar pseudoacinar pattern. The tridimensional reconstruction allows us to recognize the true structure of the glandular units. They are made up of two or three tubules closely arranged around a blood vessel, the endocrine component being disposed in the facing aspects of the tubules, around the vessel. Silver methods, Giemsa, and peroxidase-antiperoxidase techniques for light microscopy, immunogold, and routine methods for electron microscopy were used to demonstrate the regulatory peptide-producing cells present in the endocrine pancreas. Four major pancreatic endocrine cells, immunolocalized with the light and electron microscope, have been described: glucagon-containing cells (granules of 440 nm in diameter), insulin cells (400 nm), somatostatin cells (610 nm), and pancreatic polypeptide-containing cells (460 nm).


Gen Comp Endocrinol


López J,Echevarría M,Vázquez JJ




Has Abstract


1988-08-01 00:00:00














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    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Sessa AK,Harris RM,Hofmann HA

    更新日期:2013-08-01 00:00:00

  • Changes in hormone levels in relation to breeding behavior in male bullfrogs (Rana catesbeiana) at the individual and population levels.

    abstract::Fluctuations in plasma androgen (testosterone and 5 alpha-dihydrotestosterone), corticosterone (B), and luteinizing hormone (LH) of male bullfrogs in central California were measured during the spring mating season. Androgen and LH levels generally increased in the population prior to the initiation of chorusing and e...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Mendonça MT,Licht P,Ryan MJ,Barnes R

    更新日期:1985-05-01 00:00:00

  • Post-natal corticosterone exposure affects ornaments in adult male house sparrows (Passer domesticus).

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    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Dupont SM,Grace JK,Brischoux F,Angelier F

    更新日期:2019-05-15 00:00:00

  • Development and application of an ELISA for a sex pheromone released by the male sea lamprey (Petromyzon marinus L.).

    abstract::An enzyme-linked immunosorbent assay (ELISA) has been developed for a conjugated bile acid, 7alpha,12alpha,24-trihydroxy-5alpha-cholan-3-one 24-sulfate (commonly referred to as 3-keto petromyzonol sulfate [3kPZS]), a pheromone released by reproductively mature male sea lampreys to attract sexually mature females. A po...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Yun SS,Scott AP,Siefkes MJ,Li W

    更新日期:2002-12-01 00:00:00

  • No evidence for sex-specific effects of the maternal social environment on offspring development in Japanese quail (Coturnix japonica).

    abstract::The social environment of reproducing females can cause physiological changes, with consequences for reproductive investment and offspring development. These prenatal maternal effects are often found to be sex-specific and may have evolved as adaptations, maximizing fitness of male and female offspring for their futur...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Langen EMA,von Engelhardt N,Goerlich-Jansson VC

    更新日期:2018-07-01 00:00:00

  • Plasma androgen levels, spermatogenesis, and secondary sexual characteristics in two species of plethodontid salamanders with dissociated reproductive patterns.

    abstract::In the summer of 1991 (late May to early September), I measured seasonal levels of plasma androgens in two species of plethodontid salamanders to assess the temporal relationship of elevated plasma androgen levels with spermatogenic events and with sexual behavior. In both species, spermatogenesis occurs in the spring...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Woodley SK

    更新日期:1994-11-01 00:00:00

  • [Establishment of a map of neurons in the brain of Eisenia fetida (Annelida, Oligochaeta) containing substances immunologically specific to vertebrate peptides].

    abstract::Several antisera specific to neuropeptides of vertebrates were applied to sections of the earthworm Eisenia fetida Sav. Some of them were able to reveal specific neurones of the supraoesophageal ganglion: h-GHRF, CRF, Leu- and Met-enkephalin, dynorphin, substance P, CCK-8, and CCK-8S. A map of different areas or nucle...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Lkhider M,Marcel R,Tramu G

    更新日期:1987-03-01 00:00:00

  • Relationships between CB1 cannabinoid receptors and pituitary endocrine cells in Xenopus laevis: an immunohistochemical study.

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    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Cesa R,Guastalla A,Cottone E,Mackie K,Beltramo M,Franzoni MF

    更新日期:2002-01-01 00:00:00

  • Identification, expression analysis, and functional characterization of motilin and its receptor in spotted sea bass (Lateolabrax maculatus).

    abstract::Motilin (MLN), an interdigestive hormone secreted by endocrine cells of the intestinal mucosa, binds to a G protein-coupled receptor to exert its biological function of regulating gastrointestinal motility. In the present study, we identified the prepromotilin and mln receptor (mlnr) from the spotted sea bass, Lateola...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Zhou Y,Qi X,Wen H,Zhang K,Zhang X,Li J,Li Y,Fan H

    更新日期:2019-06-01 00:00:00

  • Purification and characterization of plasma vitamin D binding protein from the snapping turtle, Chelydra serpentina.

    abstract::Vitamin D binding protein (DBP) was isolated from the plasma of the snapping turtle, Chelydra serpentina (mixed sex adult), and compared with the previously characterized dual function binding plasma protein that binds both thyroxine (T4) and vitamin D (tsTDBP) in an emydid turtle, Trachemys scripta. Purification of C...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Horowitz M,Licht P

    更新日期:1996-12-01 00:00:00

  • Production of symmetrical flatfish by controlling the timing of thyroid hormone treatment in spotted halibut Verasper variegatus.

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    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Tagawa M,Aritaki M

    更新日期:2005-04-01 00:00:00

  • Differential expression of CTGF in pre- and post-ovulatory granulosa cells in the hen ovary is regulated by TGFβ1 and gonadotrophins.

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    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Zhu G,Kang L,Yang C,Zhang X,Wang M,Jiang Y

    更新日期:2012-09-01 00:00:00

  • Transfer pathways between the ovaries and the uterus in the cebus monkeys (Cebus apella).

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    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Nagle CA,Mendizábal AF,Lahoz MM,Porta MM,Torres MI

    更新日期:2005-12-01 00:00:00

  • Seasonal reproduction of female round stingrays (Urobatis halleri): steroid hormone profiles and assessing reproductive state.

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    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Mull CG,Lowe CG,Young KA

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    journal_title:General and comparative endocrinology

    pub_type: 杂志文章,评审


    authors: Scott AP,Ellis T

    更新日期:2007-08-01 00:00:00

  • Natural variability and response interpretation of fecundity, vertebrate-like sex-steroid levels and energy status in the New Zealand mudsnail Potamopyrgus antipodarum (Gray).

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    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Gust M,Mouthon J,Queau H,Dussart C,Buronfosse T,Garric J

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    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Funkenstein B,Almuly R,Chan SJ

    更新日期:1997-09-01 00:00:00

  • Rapid decline in the concentrations of three yolk steroids during development: is it embryonic regulation?

    abstract::Maternally derived yolk steroids have been found to elicit both short-term and long-term effects on offspring phenotype. Paradoxically, their effects can be strikingly specific given the often substantial concentrations present at oviposition, and they do not appear to uniformly affect all steroid-sensitive processes....

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Paitz RT,Bowden RM

    更新日期:2009-04-01 00:00:00

  • Hormonal regulation of ion and water transport in anuran amphibians.

    abstract::Amphibians occupy a wide variety of ecological habitats, and their adaptation is made possible through the specialization of the epithelia of their osmoregulatory organs, such as the skin, kidney, and urinary bladder, which control the hydromineral and acid-base balance of their internal medium. Amphibians can change ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章,评审


    authors: Uchiyama M,Konno N

    更新日期:2006-05-15 00:00:00

  • Neurohormonal control of growth and carbohydrate metabolism by the light green cells in Lymnaea stagnalis.

    abstract::The neuroendocrine light green cells (LGCs), 4 clusters of together approximately 150 giant neurons in the cerebral ganglia of the freshwater gastropod, Lymnaea stagnalis, have been suggested to be involved in the control of growth. The present study examines in greater detail this role and possible actions on energy ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Geraerts WP

    更新日期:1992-06-01 00:00:00

  • Characterization of two new preproGnRH mRNAs in the tree shrew: first direct evidence for mesencephalic GnRH gene expression in a placental mammal.

    abstract::Reproductive maturation and regulation is centrally orchestrated by gonadotropin-releasing hormone (GnRH). GnRH produced in the vertebrate hypothalamus acts on the pituitary to regulate gonadotropins. In nonplacental mammalian species, it has recently been shown that a second GnRH gene is expressed in mesencephalic ce...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Kasten TL,White SA,Norton TT,Bond CT,Adelman JP,Fernald RD

    更新日期:1996-10-01 00:00:00

  • Development of the adrenocortical response to stress in Eurasian kestrel nestlings: defence ability, age, brood hierarchy and condition.

    abstract::The developmental hypothesis proposes that the adrenocortical response to stress during postnatal development in birds should not develop when the benefits of elevated corticosterone do not outweigh the deleterious effects on growth and development. We tested three predictions developed from this hypothesis in free-li...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Müller C,Jenni-Eiermann S,Jenni L

    更新日期:2010-09-15 00:00:00

  • In silico analysis, seasonal variation and gonadotropic regulation of jag1 and its receptor notch1 in testis of spotted snakehead Channa punctatus.

    abstract::The present study in seasonally breeding spotted snakehead Channa punctatus, for the first time in nonmammalian vertebrates, demonstrated correlation between reproductive phase-dependent testicular expression of ligand Jag1/receptor Notch1 and spermatogenic events. Testicular transcriptome sequencing data from our ear...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Roy A,Basak R,Rai U

    更新日期:2018-09-15 00:00:00

  • Urinary corticosterone metabolite responses to capture and captivity in the cane toad (Rhinella marina).

    abstract::Urinary corticosterone metabolite responses to capture have recently been shown for the first time in amphibians, and in the present study urinary corticosterone metabolite responses to capture and to confinement in captivity were measured in adult cane toads (Rhinella marina) in Queensland, Australia. An adrenocortic...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Narayan EJ,Cockrem JF,Hero JM

    更新日期:2011-09-01 00:00:00

  • Specificity of ovulation hormones of some basommatophoran species studied by means of iso- and heterospecific injections.

    abstract::Isospecific injections of intercerebral commissure (COM) extracts of L. stagnalis, L. palustris, and L. ovata (Lymnaeidae) and of extracts of COM/mediodorsal bodies complexes (COM/DB) of Bulinus truncatus (Bulinidae) and Biomphalaria glabrata (Planorbidae) induced oviposition in a high percentage of the experimental s...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Dogterom GE,van Loenhout H

    更新日期:1983-10-01 00:00:00

  • Endothelin-1 stimulates suppressor of cytokine signaling-3 gene expression in adipocytes.

    abstract::Endothelin (ET)-1 and suppressor of cytokine signaling (SOCS)-3 were respectively found to regulate energy metabolism and hormone signaling in fat cells. Although ET-1 can also regulate the expression of SOCS-3-stimulating hormones, it is still unknown whether ET-1 regulates SOCS-3 gene expression. This study investig...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Chang HH,Huang YM,Wu CP,Tang YC,Liu CW,Huang CH,Ho LT,Wu LY,Kuo YC,Kao YH

    更新日期:2012-09-15 00:00:00

  • Experimental increase in temperature affects eggshell thickness, and not egg mass, eggshell spottiness or egg composition in the great tit (Parus major).

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    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Bleu J,Agostini S,Angelier F,Biard C

    更新日期:2019-05-01 00:00:00

  • Immunoreactive gonadotropin-releasing hormone-like material in the brain and the pituitary gland during the periovulatory period in the brown trout (Salmo trutta L.): relationships with the plasma and pituitary gonadotropin.

    abstract::In fish there are few data on the gonadotropin-releasing hormone (Gn-RH) neurosecretory activity, which could explain long- and short-term variations of the gonadotropin secretion. There is no biological species specificity between mammal and fish Gn-RH; although there is a structural difference, they are, on the cont...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Breton B,Motin A,Billard R,Kah O,Geoffre S,Precigoux G

    更新日期:1986-01-01 00:00:00

  • Interactions between progesterone and androgens in the stimulation of sex behaviors in male little striped whiptail lizards, Cnemidophorus inornatus.

    abstract::Progesterone is believed to have a suppressive or inhibitory role in regulating androgen-dependent sex behaviors in male mammals and birds. Previous studies in this laboratory have revealed that in the little striped whiptail lizard (Cnemidophorus inornatus), progesterone (P) can stimulate sex behavior in a proportion...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Lindzey J,Crews D

    更新日期:1992-04-01 00:00:00

  • Neuropeptide Y-immunoreactive (NPY-ir) structures in the brain of the gar Lepisosteus oculatus (Lepisosteiformes, Osteichthyes) with special regard to their anatomical relations to gonadotropin-releasing hormone (GnRH)-ir structures in the hypothalamus an

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    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Chiba A

    更新日期:2005-07-01 00:00:00