Aberrant dendritic development in the human agyric cortex: a quantitative and qualitative Golgi study of two cases.


:A quantitative and qualitative Golgi comparison of the visual cortex from two agyric brains and of two age-matched controls is reported. In the camera lucida drawings, most pyramidal cells were oriented vertically to the pial surface in the external cellular layer, frequently with their apical dendrites directed toward the deep layers (inverted pyramidal neurons). The deep cellular layer contained pyramidal and polymorphic neurons normally found in the second to fourth cortical layers. In quantitative analysis of the agyric cortex of a ten-month-old patient, relative immaturity of basal dendritic arborization was apparent together with a bipolar configuration of dendritic development of the pyramidal neurons. The 3-year-old patient had a significant delay in apical dendritic arborization (shorter branch length, decreased number of dendritic intersections) compared with his age-matched normal control. The pathogenesis of the abnormal dendritic development in agyria is discussed.


Clin Neuropathol


Clinical neuropathology


Takada K,Becker LE,Chan F


Has Abstract


1988-05-01 00:00:00










  • Prevention of diabetic foot complications.

    abstract::This paper discussed the importance of prevention of diabetic foot ulcers and our institution's protocol for prevention, reviewing the existing evidence in the literature regarding the effectiveness of the preventive approach. Diabetes mellitus is the second most significant cause of disease in Singapore after ischaem...

    journal_title:Singapore medical journal

    pub_type: 杂志文章


    authors: Nather A,Cao S,Chen JLW,Low AY

    更新日期:2018-06-01 00:00:00

  • Evaluation of Malondialdehyde Low-Density Lipoprotein Stratified by Low-Density Lipoprotein Cholesterol.

    abstract:BACKGROUND:Malondialdehyde low-density lipoprotein (MDA-LDL) is a major form of oxidized LDL and considered to be more atherogenic than LDL. Information on major determinants of MDA-LDL and their association in subjects who are not under treatment for diabetes mellitus and dyslipidemia is limited. METHODS:This study i...

    journal_title:Clinical laboratory

    pub_type: 杂志文章


    authors: Moriyama K,Takahashi E

    更新日期:2017-07-01 00:00:00

  • Occlusion of the ascending pharyngeal artery during carotid artery surgery: importance and technique.

    abstract:AIM:In surgeries involving clamping, opening and repairing the carotid artery such as carotid endarterectomy (CEA) and proximal anastomosis at radial artery (RA) grafting, back-bleeding, often due to insufficient occlusion of the ascending pharyngeal artery (APA), must be avoided. In 96% of cases the APA originates at ...

    journal_title:Turkish neurosurgery

    pub_type: 杂志文章


    authors: Umeoka K,Mizunari T,Murai Y,Kobayashi S,Morita A

    更新日期:2014-01-01 00:00:00

  • Embryonated duck ("balut") eggshell aspiration in a one-year-old boy.

    abstract::A one-year-old boy with two months' chronic cough and dysphonia, unresponsive to therapy for pneumonia, had a radiopaque, wedge-shaped tracheal foreign body noted on anteroposterior, but not lateral radiographs, and he eventually became aphonic. Laryngoscopy yielded a subglottic embryonated duck eggshell. Foreign body...

    journal_title:Singapore medical journal

    pub_type: 杂志文章


    authors: Lapeña JF Jr

    更新日期:2009-05-01 00:00:00

  • Fecal contamination of food, water, hands, and kitchen utensils at the household level in rural areas of Peru.

    abstract::The study described in this article evaluated sources of contamination of children's food and drinking water in rural households in the highlands of Peru. Samples from children's meals, drinking water, kitchen utensils, and caregivers' and children's hands were analyzed for total coliforms and E. coli counts using Pet...

    journal_title:Journal of environmental health

    pub_type: 杂志文章


    authors: Gil AI,Lanata CF,Hartinger SM,Mäusezahl D,Padilla B,Ochoa TJ,Lozada M,Pineda I,Verastegui H

    更新日期:2014-01-01 00:00:00

  • Monitoring of national drug policies--regional comparison between Bulgaria, Romania, Macedonia, Bosnia Herzegovina.

    abstract::After the profound economic and political changes most of the East European countries started market-oriented reforms. During the last 10 years rapid development of the private pharmaceutical sector and a slow privatisation process was observed. The balance between the private and public sector became very important f...

    journal_title:Central European journal of public health

    pub_type: 杂志文章


    authors: Petrova GI

    更新日期:2001-11-01 00:00:00

  • The role of immunohistochemistry in the diagnosis of urinary bladder neoplasms.

    abstract::The spectrum of neoplasms involving the urinary bladder is diverse, and, at times, different entities with distinct prognostic and managerial implications may have significant morphologic overlap. The presence of a neoplasm with an unusual morphologic appearance, such as an undifferentiated spindled, or plasmacytoid p...

    journal_title:Seminars in diagnostic pathology

    pub_type: 杂志文章,评审


    authors: McKenney JK,Amin MB

    更新日期:2005-02-01 00:00:00

  • Precipitating factors and patient outcomes in acute kidney injury treated with renal replacement therapy.

    abstract::Acute kidney injury (AKI) is not uncommon in acute hospital admissions. AKI treated with renal replacement therapy (RRT) has a wide spectrum of causes and the mortality rate at 90 days, approaches 50%. This study was performed to analyse the identifiable causes and outcomes of all cases of AKI treated with RRT in the ...

    journal_title:Scottish medical journal

    pub_type: 杂志文章


    authors: McMillan M,Mactier R

    更新日期:2011-02-01 00:00:00

  • Auditory-visual stimulus pairing enhances perceptual learning in a songbird.

    abstract::In many oscine birds, song learning is affected by social variables, for example the behaviour of a tutor. This implies that both auditory and visual perceptual systems should be involved in the acquisition process. To examine whether and how particular visual stimuli can affect song acquisition, we tested the impact ...

    journal_title:Animal behaviour

    pub_type: 杂志文章


    authors: Hultsch H,Schleuss F,Todt D

    更新日期:1999-07-01 00:00:00

  • The treatment of stab wounds in about 1600. The death of the three Henry's of France.

    abstract::On the 10th July 1559, Henry II died of posttraumatic meningo-encephalitis due to a perforating trauma through his left eye. His third son, the last Valois king, Henry III succumbed on 5th of August 1589, four days after having been daggered in the abdomen. The sister's husband of the latter, king Henry IV, the first ...

    journal_title:Acta chirurgica Belgica

    pub_type: 传,历史文章,杂志文章


    authors: Broos PL

    更新日期:1993-09-01 00:00:00

  • [Restoration of upper-limb function in patients with cervical spinal cord lesion].

    abstract:PURPOSE OF THE STUDY:Injury to the spinal chord at the C5 level results in a severe handicap to the patient because of a loss of active motion of the wrist and hand. Selected surgical procedures can effectively restore active extension of the wrist and provide conditions for some vital pinching and gripping abilities. ...

    journal_title:Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca

    pub_type: 杂志文章


    authors: Cižmář I,Ehler E,Calabová N,Vinter R,Palčák J

    更新日期:2010-01-01 00:00:00

  • [Motor fluctuations].

    abstract::The therapeutic approach of motor fluctuations is based on the need for recognizing various types of motor fluctuations for each patient by a meticulous interrogation and also to have a good knowledge of the pharmacology of the various anti-parkinsonian drugs. The treatment of the morning akinesia is linked to the use...

    journal_title:Revue neurologique

    pub_type: 杂志文章,评审


    authors: Durif F

    更新日期:2002-12-01 00:00:00

  • [Technique of inclusion in epoxy resin for alternative photonic and ultrastructural examination (author's transl)].

    abstract::Fragmentation of the samples in small blocks for electron microscopy fail to allow topographic study. Therefore a method fod embedding large blocks in epon is detailed here. It provides large semi-thin sections for photomic examination and, after making a "mesa", ultrathin for ultrastructural study. ...

    journal_title:Annales de pathologie

    pub_type: 杂志文章


    authors: Barioz CM,Schaber S,Stoebner P

    更新日期:1982-01-01 00:00:00

  • Report - Report on the heterozygosis mutations of c.567dupT, p.(Ile190Tyrfs*13) of MMACHC gene in 1 Child patient with methylmalonic academia.

    abstract::This article reported 1 child patient with early-onset methylmalonic acidemia and proceeded gene detection for the child and his parents. The detecting results showed that there were respectively heterozygosis mutations of c.609G>A,p.(Trp203*) and c.567dupT,p.(Ile190Tyrfs*13) in the MMA CHC gene of child's parents, an...

    journal_title:Pakistan journal of pharmaceutical sciences

    pub_type: 杂志文章


    authors: Liu K,Chen G,Ma Y,Xian Y,Zhang Z

    更新日期:2016-05-01 00:00:00

  • Effects of acute moderate hypoxemia on kinetics of metoclopramide and its metabolites in chronically instrumented sheep.

    abstract::Hypoxemia is known to induce various physiological changes which can result in alteration in drug pharmacokinetics. To examine the effect of acute moderate hypoxemia on metoclopramide (MCP) pharmacokinetics, a continuous 14-hour infusion of MCP during a normoxemic, hypoxemic and subsequent normoxemic period was conduc...

    journal_title:Archives of pharmacal research

    pub_type: 杂志文章


    authors: Kim J,Riggs KW,Rurak DW

    更新日期:2002-10-01 00:00:00

  • Impact of MTHFR rs1801133, MTHFR rs1801131 and ABCB1 rs1045642 polymorphisms with increased susceptibility of rheumatoid arthritis in the West Algerian population: A case-control study.

    abstract::Rheumatoid arthritis (RA) is an autoimmune disease that results in a chronic systemic inflammation. A few genetic epidemiologic studies found a potential association between genetic polymorphisms C677T (rs1801133) and A1298C (rs1801131) of methylenetatrahydrofolate reductase (MTHFR) gene and C3435T (rs1045642) of ATP-...

    journal_title:Acta reumatologica portuguesa

    pub_type: 杂志文章


    authors: Boughrara W,Aberkane M,Fodil M,Benzaoui A,Dorgham S,Zemani F,Dahmani C,Petit Teixeira E,Boudjema A

    更新日期:2015-10-01 00:00:00

  • Early contribution of Alexandria medical school to the anatomy, physiology and pathology of the nervous system.

    abstract::Alexandria's famous medical school was established about 300 BC. It was the seat of learning for many Greco-Roman physicians. The physiologist Erasistratus, the anatomist Herophilus - named the Father of Anatomy were outstanding pioneers. Their work and discoveries of the nervous system, its structure and function, ar...

    journal_title:Revue neurologique

    pub_type: 历史文章,杂志文章,评审


    authors: Pearce JMS

    更新日期:2019-03-01 00:00:00

  • Relative Importance of Traditional Risk Factors for Malignant Melanoma in the Czech Population.

    abstract:AIM:The Czech Republic is one of the leading European countries in incident cases of malignant melanoma (MM), which is on the rise. The study objective was to assess the strength of associations between MM and the known generally accepted risk factors for MM in the population of the Czech Republic. METHODS:The study w...

    journal_title:Central European journal of public health

    pub_type: 杂志文章


    authors: Rajská L,Göpfertová D,Hercogová J,Jiráková A,Sečníková Z,Rob F,Šmerhovský Z

    更新日期:2016-12-01 00:00:00

  • Synthesis and anticonvulsant properties of a series of N-substituted 2-aza-spiro[4.5]decane-1,3-diones and 8-phenyl-2-aza-spiro[4.5]decane-1,3-diones.

    abstract::A series of N-phenyl-2-aza-spiro[4.5]decane-1,3-diones [III-VIIII] structurally related to the previously described N-phenyl-3-arylpyrrolidine-2,5-dione (11) was synthesized and tested for their anticonvulsant activity in the maximum electroshock seizure (MES) and metrazole seizure threshold (sc. MET) tests. The most ...

    journal_title:Acta poloniae pharmaceutica

    pub_type: 杂志文章


    authors: Obniska J

    更新日期:2004-11-01 00:00:00

  • The effect of meteorological factors on airborne Betula pollen concentrations in Lublin (Poland).

    abstract::The present study investigated the pattern of the birch atmospheric pollen seasons in Lublin in the period 2001-2010. Pollen monitoring was conducted using a Lanzoni VPPS 2000 sampler. The atmospheric pollen seasons were determined with the 98% method. Regression analysis was used to determine correlations between met...


    pub_type: 杂志文章


    authors: Piotrowska K,Kubik-Komar A

    更新日期:2012-12-01 00:00:00

  • Blood loss closely correlates with body mass index in total hip arthroplasty performed through direct lateral approach.

    abstract:OBJECTIVE:To investigate total blood loss (TBL), intraoperative blood loss (IBL), post-operative drainage (POD), and other related variables in total hip arthroplasty (THA) performed through direct lateral approach. METHODS:This study was completed in Shanghai Sixth People's Hospital, Shanghai, China, between January ...

    journal_title:Saudi medical journal

    pub_type: 杂志文章


    authors: Yu XW,Ai ZS,Gao YS,Zhang CQ

    更新日期:2013-07-01 00:00:00

  • [Erysipelas: epidemiological, clinical and therapeutic data (111 cases)].

    abstract::A retrospective study of 111 patients admitted to the Dermatology department of the Bichat hospital, Paris, between 1981 and 1988 for treatment of erysipelas revealed the following data: 1. Erysipelas was located on the lower limbs in 88.3 p. 100 of the cases and on the face in only 9.8 p. 100. 2. Facilitating and/or ...

    journal_title:Annales de dermatologie et de venereologie

    pub_type: 杂志文章


    authors: Crickx B,Chevron F,Sigal-Nahum M,Bilet S,Faucher F,Picard C,Lazareth I,Belaich S

    更新日期:1991-01-01 00:00:00

  • Lesion preparation prior to stenting.

    abstract::Lesion preparation before stent implantation remains an essential component of the contemporary practice of coronary stent implantation in patients with long lesions, ostial lesions, chronic total occlusions, bifurcations, and calcified or nondilatable lesions. The goal of lesion preparation in these patients is to fa...

    journal_title:Reviews in cardiovascular medicine

    pub_type: 杂志文章,评审


    authors: Moses JW,Carlier S,Moussa I

    更新日期:2004-01-01 00:00:00

  • Activation of NK activity and auto-reactive cytotoxicity after hepatectomy.

    abstract::Spleen cells serially sampled from normal mice following partial hepatectomy were tested for antibody-dependent cellular cytotoxicity (ADCC) and natural killer (NK) activity. There was a marked augmentation of these activities of spleen cells from the hepatectomized animals, compared to cells from controls with a simp...

    journal_title:Acta medica Okayama

    pub_type: 杂志文章


    authors: Ono M,Tanaka N,Orita K

    更新日期:1984-04-01 00:00:00

  • Crushing or splitting medications: unrecognized hazards.

    abstract::Given the high use and the cost of medications in the current economy, one way older adults may save money on prescription costs is to split some of their medications in half. However, not all oral medications can be split. Splitting inappropriate medications such as extended-release tablets can be harmful and in some...

    journal_title:Journal of gerontological nursing

    pub_type: 杂志文章


    authors: Gill D,Spain M,Edlund BJ

    更新日期:2012-01-01 00:00:00

  • Elite athletes refine their internal clocks.

    abstract::Evaluating time properly is crucial for everyday activities from fundamental behaviors to refined coordinative movements such as in sport playing. Lately the concept of the existence of a unique internal clock for evaluating time in different scales has been challenged by recent neurophysiology studies. Here we provid...

    journal_title:Motor control

    pub_type: 杂志文章


    authors: Chen YH,Cesari P

    更新日期:2015-01-01 00:00:00

  • Function of neurotrophic factors beyond the nervous system: inflammation and autoimmune demyelination.

    abstract::In the nervous system, neurotrophic factors play a role during development, especially for the differentiation of neuronal and glial cells. Moreover, they promote cell survival of neurons, axons, and oligodendrocytes, as well as their precursors, in vitro and in lesional paradigms. In recent years, several functions o...

    journal_title:Critical reviews in immunology

    pub_type: 杂志文章,评审


    authors: Linker R,Gold R,Luhder F

    更新日期:2009-01-01 00:00:00

  • Prophylaxis against infective endocarditis. A review of current international guidelines.

    abstract::The purpose of this review is to discuss current international guidelines on the prevention of infective endocarditis (IE). It has long been considered that all patients with heart conditions predisposing to IE should receive antibiotic prophylaxis when undergoing procedures leading to bacteremia with organisms known ...

    journal_title:Saudi medical journal

    pub_type: 杂志文章


    authors: Al-Yousef SA

    更新日期:2009-10-01 00:00:00

  • Spontaneous rupture of splenic hemangioma in puerperium.

    abstract::Atraumatic splenic rupture is a rare clinical entity and in the absence of trauma, the diagnosis and treatment are often delayed. In this article the authors discuss a case of a 45-year-old woman, gravida 5, para 4, with spontaneous splenic rupture on her second postpartum day. The rupture was related to a splenic hem...

    journal_title:Clinical and experimental obstetrics & gynecology

    pub_type: 杂志文章


    authors: Carta G,D'Alfonso A,Nallbani A,Palermo P,Franchi V,Patacchiola F

    更新日期:2012-01-01 00:00:00

  • Identification of campylobacters from bovine and ovine faeces.

    abstract::Campylobacters isolated in Scotland and the north of England from bovine (497 isolates) and ovine (51 isolates) faeces were studied in order to determine which simple methods would be useful for identification of groups and species. By means of the catalase test, growth and microscopic characteristics, coccal transfor...

    journal_title:Revista Argentina de microbiologia

    pub_type: 杂志文章


    authors: Terzolo HR

    更新日期:1988-04-01 00:00:00