Virological, immunological and pathological findings of transplacentally transmitted bluetongue virus serotype 1 in IFNAR1-blocked mice during early and mid gestation.

abstract：:The aim of this systematic review was to assess the performance of anthropometric tools to determine obesity in the general population (CRD42018086888). Our review included 32 studies. To detect obesity with body mass index (BMI), the meta-analyses rendered a sensitivity of 51.4% (95% CI 38.5-64.2%) and a specificity ...

journal_title：Scientific reports

authors： Sommer I,Teufer B,Szelag M,Nussbaumer-Streit B,Titscher V,Klerings I,Gartlehner G

更新日期：2020-07-29 00:00:00

abstract：:Anatase TiO2 has been suggested as a potential sodium anode material, but the low electrical conductivity of TiO2 often limits the rate capability, resulting in poor electrochemical properties. To address this limitation, we propose graphene-wrapped anatase TiO2 nanofibers (rGO@TiO2 NFs) through an effective wrapping ...

journal_title：Scientific reports

authors： Yeo Y,Jung JW,Park K,Kim ID

更新日期：2015-09-10 00:00:00

abstract：:Variability in the x-ray tube current used in computed tomography may affect quantitative features extracted from the images. To investigate these effects, we scanned the Credence Cartridge Radiomics phantom 12 times, varying the tube current from 25 to 300 mA∙s while keeping the other acquisition parameters constant....

journal_title：Scientific reports

authors： Mackin D,Ger R,Dodge C,Fave X,Chi PC,Zhang L,Yang J,Bache S,Dodge C,Jones AK,Court L

更新日期：2018-02-05 00:00:00

abstract：:Hepatocyte-specific HMGB1 deletion has been found to worsen the injury and inflammation in liver ischemia-reperfusion injury (IRI), highlighting a role for intracellular HMGB1 in cellular protection. Down-regulation of nuclear HMGB1 by small interfering RNA (siRNA) might not only decrease its injurious extracellular r...

journal_title：Scientific reports

authors： Zhao G,Fu C,Wang L,Zhu L,Yan Y,Xiang Y,Zheng F,Gong F,Chen S,Chen G

更新日期：2017-04-06 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most common liver cancer, with a very poor prognosis. There is an urgent need for an effective therapy for HCC. Ginsenoside Rh2 (GRh2) has been shown to significantly inhibit growth of some types of cancer, whereas its effects on HCC have not been examined. Here, we treated human ...

journal_title：Scientific reports

authors： Yang Z,Zhao T,Liu H,Zhang L

更新日期：2016-01-19 00:00:00

abstract：:Patterns of temperature fluctuations in nature affect numerous biological processes, yet, empirical studies often utilize constant temperature treatments. This can limit our understanding of how thermally sensitive species respond to ecologically relevant temperatures. Research on turtles with temperature-dependent se...

journal_title：Scientific reports

authors： Carter AW,Sadd BM,Tuberville TD,Paitz RT,Bowden RM

更新日期：2018-01-08 00:00:00

abstract：:The association between blood urea nitrogen to creatinine ratio (UCR) and survival is uncertain in hemodialysis patients. We examined the influence of UCR on mortality and morbidity in hemodialysis patients. A total of 3,401 hemodialysis patients were prospectively followed for 4 years. The association between UCR wit...

journal_title：Scientific reports

authors： Tanaka S,Ninomiya T,Taniguchi M,Tokumoto M,Masutani K,Ooboshi H,Kitazono T,Tsuruya K

更新日期：2017-11-02 00:00:00

abstract：:Ultrafast betatron x-ray emission from electron oscillations in laser wakefield acceleration (LWFA) has been widely investigated as a promising source. Betatron x-rays are usually produced via self-injected electron beams, which are not controllable and are not optimized for x-ray yields. Here, we present a new method...

journal_title：Scientific reports

authors： Huang K,Li YF,Li DZ,Chen LM,Tao MZ,Ma Y,Zhao JR,Li MH,Chen M,Mirzaie M,Hafz N,Sokollik T,Sheng ZM,Zhang J

更新日期：2016-06-08 00:00:00

abstract：:Different subtypes of bone marrow-derived stem cells are characterized by varying functionality and activity after transplantation into the infarcted heart. Improvement of stem cell therapeutics requires deep knowledge about the mechanisms that mediate the benefits of stem cell treatment. Here, we demonstrated that co...

journal_title：Scientific reports

authors： Lemcke H,Gaebel R,Skorska A,Voronina N,Lux CA,Petters J,Sasse S,Zarniko N,Steinhoff G,David R

更新日期：2017-08-29 00:00:00

abstract：:Arrestin domain-containing 3 (ARRDC3) is a tumor suppressor whose expression is either lost or suppressed in basal-like breast cancer (BLBC). However, the mechanism by which BLBC suppresses ARRDC3 expression is not established. Here, we show that expression of ARRDC3 in BLBC cells is suppressed at the transcriptional ...

journal_title：Scientific reports

authors： Soung YH,Pruitt K,Chung J

更新日期：2014-01-24 00:00:00

abstract：:One of the famous results of network science states that networks with heterogeneous connectivity are more susceptible to epidemic spreading than their more homogeneous counterparts. In particular, in networks of identical nodes it has been shown that network heterogeneity, i.e. a broad degree distribution, can lower ...

journal_title：Scientific reports

authors： Yang H,Tang M,Gross T

更新日期：2015-08-21 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been found to play important roles in various biological processes; however, many of their functions remain unclear. In this study, we present a novel approach to identify the lncRNA-associated protein-protein interaction (PPI) modules and ascertain their functions in human lung squ...

journal_title：Scientific reports

authors： Wu CH,Hsu CL,Lu PC,Lin WC,Juan HF,Huang HC

更新日期：2016-10-27 00:00:00

abstract：:Convenient drug-resistance testing of viral mutants is indispensable to effective treatment of viral infection. We developed a novel fluorometric assay for phenotypic differentiation of drug-resistant mutants of human immunodeficiency virus-I protease (HIV-PR) which uses enzymatic and peptide-specific fluorescence (FL...

journal_title：Scientific reports

authors： Zhu Q,Yu Z,Kabashima T,Yin S,Dragusha S,El-Mahdy AF,Ejupi V,Shibata T,Kai M

更新日期：2015-05-19 00:00:00

abstract：:Cohesins are vital for chromosome organisation during meiosis and mitosis. In addition to the important function in sister chromatid cohesion, these complexes play key roles in meiotic recombination, DSB repair, homologous chromosome pairing and segregation. Egg-laying mammals (monotremes) feature an unusually complex...

journal_title：Scientific reports

authors： Casey AE,Daish TJ,Barbero JL,Grützner F

更新日期：2017-06-26 00:00:00

abstract：:We report the high susceptibility of several clinical isolates of Propionibacterium acnes from different sources (skin, bone, wound exudates, abscess or blood contamination) to the head-to-tail cyclized bacteriocin AS-48. This peptide is a feasible candidate for further pharmacological development against this bacteri...

journal_title：Scientific reports

authors： Cebrián R,Arévalo S,Rubiño S,Arias-Santiago S,Rojo MD,Montalbán-López M,Martínez-Bueno M,Valdivia E,Maqueda M

更新日期：2018-08-06 00:00:00

abstract：:Long-term high-fat diet (HFD) consumption leads to not only obese-insulin resistance, but also impaired left ventricular (LV) function. Vagus nerve stimulation (VNS) has been shown to exert cardioprotection. However, its effects on the heart and metabolic parameters under obese-insulin resistant condition is not known...

journal_title：Scientific reports

authors： Samniang B,Shinlapawittayatorn K,Chunchai T,Pongkan W,Kumfu S,Chattipakorn SC,KenKnight BH,Chattipakorn N

更新日期：2016-02-01 00:00:00

abstract：:Fresh produce vegetables are colonized by different bacterial species, some of which are antagonistic to microbes that cause postharvest losses. However, no comprehensive assessment of the diversity and composition of bacteria inhabiting surfaces of fresh pepper plants grown under different conditions has been conduct...

journal_title：Scientific reports

authors： Mamphogoro TP,Maboko MM,Babalola OO,Aiyegoro OA

更新日期：2020-05-22 00:00:00

abstract：:Human Influenza A virus undergoes recurrent changes in the hemagglutinin (HA) surface protein, primarily involved in the human antibody recognition. Relevant antigenic changes, enabling the virus to evade host immune response, have been recognized to occur in parallel to multiple mutations at antigenic sites in HA. Ye...

journal_title：Scientific reports

authors： Tria F,Pompei S,Loreto V

更新日期：2013-01-01 00:00:00

abstract：:Circadian clocks keep time via ~ 24 h transcriptional feedback loops. In Drosophila, CLOCK-CYCLE (CLK-CYC) activators and PERIOD-TIMELESS (PER-TIM) repressors are feedback loop components whose transcriptional status varies over a circadian cycle. Although changes in the state of activators and repressors has been cha...

journal_title：Scientific reports

authors： Mahesh G,Rivas GBS,Caster C,Ost EB,Amunugama R,Jones R,Allen DL,Hardin PE

更新日期：2020-10-21 00:00:00

abstract：:Anaerobic ammonium oxidation (anammox) is known to autotrophically convert ammonium to dinitrogen gas with nitrite as the electron acceptor, but little is known about their released microbial products and how these are relative to heterotrophic growth in anammox system. In this work, we applied a mathematical model to...

journal_title：Scientific reports

authors： Liu Y,Sun J,Peng L,Wang D,Dai X,Ni BJ

更新日期：2016-06-07 00:00:00

abstract：:Biofertilizer production and application for sustainable agriculture is already a reality. The methods for biofertilizers delivery in crop fields are diverse. Although foliar spray is gaining wide acceptance, little is known about the influence that the biochemical features of leaves have on the microbial colonization...

journal_title：Scientific reports

authors： Ramírez-Ordorica A,Valencia-Cantero E,Flores-Cortez I,Carrillo-Rayas MT,Elizarraraz-Anaya MIC,Montero-Vargas J,Winkler R,Macías-Rodríguez L

更新日期：2020-05-21 00:00:00

abstract：:Since the SOX2 amplification was identified in lung squamous cell carcinoma (lung SCC), SOX2 transcriptional downstream targets have been actively investigated; however, such targets are often cell line specific. Here, in order to identify highly consensus SOX2 downstream genes in lung SCC cells, we used RNA-seq data ...

journal_title：Scientific reports

authors： Fukazawa T,Guo M,Ishida N,Yamatsuji T,Takaoka M,Yokota E,Haisa M,Miyake N,Ikeda T,Okui T,Takigawa N,Maeda Y,Naomoto Y

更新日期：2016-02-05 00:00:00

abstract：:Deconvolution is widely used to improve the contrast and clarity of a 3D focal stack collected using a fluorescence microscope. But despite being extensively studied, deconvolution algorithms can introduce reconstruction artifacts when their underlying noise models or priors are violated, such as when imaging biologic...

journal_title：Scientific reports

authors： Ikoma H,Broxton M,Kudo T,Wetzstein G

更新日期：2018-07-31 00:00:00

abstract：:Comet assay is a widely used method, especially in the field of genotoxicity, to quantify and measure DNA damage visually at the level of individual cells with high sensitivity and efficiency. Generally, computer programs are used to analyze comet assay output images following two main steps. First, each comet region ...

journal_title：Scientific reports

authors： Hong Y,Han HJ,Lee H,Lee D,Ko J,Hong ZY,Lee JY,Seok JH,Lim HS,Son WC,Sohn I

更新日期：2020-11-03 00:00:00

abstract：:Intergroup competition has an important impact on the survival and fitness of individuals in group-living species. However, factors influencing the probability of winning an encounter are not fully understood. We studied the influence of numerical advantage and location of the encounter on the chances of winning in ei...

journal_title：Scientific reports

authors： Koch F,Signer J,Kappeler PM,Fichtel C

更新日期：2016-06-22 00:00:00

abstract：:Understanding the neural basis of poor impulse control in Internet addiction (IA) is important for understanding the neurobiological mechanisms of this syndrome. The current study investigated how neuronal pathways implicated in response inhibition were affected in IA using a Go-Stop paradigm and functional magnetic r...

journal_title：Scientific reports

authors： Li B,Friston KJ,Liu J,Liu Y,Zhang G,Cao F,Su L,Yao S,Lu H,Hu D

更新日期：2014-05-22 00:00:00

abstract：:Severe sepsis or septic shock is one of the rising causes for mortality worldwide representing nearly 10% of intensive care unit admissions. Susceptibility to sepsis is identified to be mediated by innate pattern recognition receptors and responsive signaling pathways of the host. The c-Jun N-terminal Kinase (JNK)-med...

journal_title：Scientific reports

authors： Prasad KD,Trinath J,Biswas A,Sekar K,Balaji KN,Guru Row TN

更新日期：2014-11-27 00:00:00

abstract：:Defense mechanisms of plant genomes can epigenetically inactivate repetitive sequences and exogenous transgenes. Loss of mutant phenotypes in intronic T-DNA insertion lines by interaction with another T-DNA locus, termed T-DNA suppression, has been observed in Arabidopsis thaliana, although the molecular basis of esta...

journal_title：Scientific reports

authors： Osabe K,Harukawa Y,Miura S,Saze H

更新日期：2017-03-24 00:00:00

abstract：:Here we report the study of two bioengineered variants of human trace amine-associated receptor 5 (hTAAR5) that were expressed in stable tetracycline-inducible HEK293S cell lines. A systematic detergent screen showed that fos-choline-14 was the optimal detergent to solubilize and subsequently purify the receptors. Mil...

journal_title：Scientific reports

authors： Wang X,Corin K,Rich C,Zhang S

更新日期：2011-01-01 00:00:00

abstract：:V-domain immunoglobulin (Ig) suppressor of T cell activation (VISTA) is an immune checkpoint that maintains peripheral T cell quiescence and inhibits anti-tumor immune responses. VISTA functions by dampening the interaction between myeloid cells and T cells, orthogonal to PD-1 and other checkpoints of the tumor-T cell...

journal_title：Scientific reports

authors： Mehta N,Maddineni S,Kelly RL,Lee RB,Hunter SA,Silberstein JL,Parra Sperberg RA,Miller CL,Rabe A,Labanieh L,Cochran JR

更新日期：2020-09-16 00:00:00