Heterogeneous integration of single-crystalline complex-oxide membranes.

Abstract:

:Complex-oxide materials exhibit a vast range of functional properties desirable for next-generation electronic, spintronic, magnetoelectric, neuromorphic, and energy conversion storage devices1-4. Their physical functionalities can be coupled by stacking layers of such materials to create heterostructures and can be further boosted by applying strain5-7. The predominant method for heterogeneous integration and application of strain has been through heteroepitaxy, which drastically limits the possible material combinations and the ability to integrate complex oxides with mature semiconductor technologies. Moreover, key physical properties of complex-oxide thin films, such as piezoelectricity and magnetostriction, are severely reduced by the substrate clamping effect. Here we demonstrate a universal mechanical exfoliation method of producing freestanding single-crystalline membranes made from a wide range of complex-oxide materials including perovskite, spinel and garnet crystal structures with varying crystallographic orientations. In addition, we create artificial heterostructures and hybridize their physical properties by directly stacking such freestanding membranes with different crystal structures and orientations, which is not possible using conventional methods. Our results establish a platform for stacking and coupling three-dimensional structures, akin to two-dimensional material-based heterostructures, for enhancing device functionalities8,9.

journal_name

Nature

journal_title

Nature

authors

Kum HS,Lee H,Kim S,Lindemann S,Kong W,Qiao K,Chen P,Irwin J,Lee JH,Xie S,Subramanian S,Shim J,Bae SH,Choi C,Ranno L,Seo S,Lee S,Bauer J,Li H,Lee K,Robinson JA,Ross CA,Schlom DG,Rzchowski MS,Eom CB,Kim J

doi

10.1038/s41586-020-1939-z

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

75-81

issue

7793

eissn

0028-0836

issn

1476-4687

pii

10.1038/s41586-020-1939-z

journal_volume

578

pub_type

杂志文章

相关文献

NATURE文献大全
  • Transient dynamics of an altered large marine ecosystem.

    abstract::Overfishing of large-bodied benthic fishes and their subsequent population collapses on the Scotian Shelf of Canada's east coast and elsewhere resulted in restructuring of entire food webs now dominated by planktivorous, forage fish species and macroinvertebrates. Despite the imposition of strict management measures i...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature10285

    authors: Frank KT,Petrie B,Fisher JA,Leggett WC

    更新日期:2011-07-27 00:00:00

  • Cloned human phenylalanine hydroxylase gene allows prenatal diagnosis and carrier detection of classical phenylketonuria.

    abstract::The human gene for the hepatic enzyme phenylalanine hydroxylase has been cloned and used to analyse the phenylalanine hydroxylase locus in the human genome. The detection of polymorphisms in this locus by several restriction enzymes has allowed feasibility studies of prenatal diagnosis of classical phenylketonuria and...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/306151a0

    authors: Woo SL,Lidsky AS,Güttler F,Chandra T,Robson KJ

    更新日期:1983-11-10 00:00:00

  • DNA cloning in Streptomyces: resistance genes from antibiotic-producing species.

    abstract::The biochemical and morphological differentiation of actinomycetes makes them academically and economically interesting. Their secondary metabolites provide the majority of medically and agriculturally important antibiotics (streptomycete genes may also be the primary source of clinically important antibiotic resistan...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/286525a0

    authors: Thompson CJ,Ward JM,Hopwood DA

    更新日期:1980-07-31 00:00:00

  • Identification of a proline residue as a transduction element involved in voltage gating of gap junctions.

    abstract::Gap junction channels are structurally distinct from other ion channels in that they comprise two hemichannels which interact head-to-head to form an aqueous channel between cells. Intercellular voltage differences together with increased intracellular concentrations of H+ and Ca2+ cause closure of these normally pate...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/365847a0

    authors: Suchyna TM,Xu LX,Gao F,Fourtner CR,Nicholson BJ

    更新日期:1993-10-28 00:00:00

  • Machine learning helps to hunt down the cause of a paralysing illness.

    abstract:: ...

    journal_title:Nature

    pub_type: 新闻

    doi:10.1038/d41586-018-07631-3

    authors: Reardon S

    更新日期:2018-12-01 00:00:00

  • Molecular basis of agonism and antagonism in the oestrogen receptor.

    abstract::Oestrogens are involved in the growth, development and homeostasis of a number of tissues. The physiological effects of these steroids are mediated by a ligand-inducible nuclear transcription factor, the oestrogen receptor (ER). Hormone binding to the ligand-binding domain (LBD) of the ER initiates a series of molecul...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/39645

    authors: Brzozowski AM,Pike AC,Dauter Z,Hubbard RE,Bonn T,Engström O,Ohman L,Greene GL,Gustafsson JA,Carlquist M

    更新日期:1997-10-16 00:00:00

  • Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor.

    abstract::Calcitonin gene-related peptide (CGRP) is a widely expressed neuropeptide that has a major role in sensory neurotransmission. The CGRP receptor is a heterodimer of the calcitonin receptor-like receptor (CLR) class B G-protein-coupled receptor and a type 1 transmembrane domain protein, receptor activity-modifying prote...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/s41586-018-0535-y

    authors: Liang YL,Khoshouei M,Deganutti G,Glukhova A,Koole C,Peat TS,Radjainia M,Plitzko JM,Baumeister W,Miller LJ,Hay DL,Christopoulos A,Reynolds CA,Wootten D,Sexton PM

    更新日期:2018-09-01 00:00:00

  • T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection.

    abstract::The clinical course of autoimmune and infectious disease varies greatly, even between individuals with the same condition. An understanding of the molecular basis for this heterogeneity could lead to significant improvements in both monitoring and treatment. During chronic infection the process of T-cell exhaustion in...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature14468

    authors: McKinney EF,Lee JC,Jayne DR,Lyons PA,Smith KG

    更新日期:2015-07-30 00:00:00

  • A per-cent-level determination of the nucleon axial coupling from quantum chromodynamics.

    abstract::The axial coupling of the nucleon, gA, is the strength of its coupling to the weak axial current of the standard model of particle physics, in much the same way as the electric charge is the strength of the coupling to the electromagnetic current. This axial coupling dictates the rate at which neutrons decay to proton...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/s41586-018-0161-8

    authors: Chang CC,Nicholson AN,Rinaldi E,Berkowitz E,Garron N,Brantley DA,Monge-Camacho H,Monahan CJ,Bouchard C,Clark MA,Joó B,Kurth T,Orginos K,Vranas P,Walker-Loud A

    更新日期:2018-06-01 00:00:00

  • In situ detection of collisionless reconnection in the Earth's magnetotail.

    abstract::Magnetic reconnection is the process by which magnetic field lines of opposite polarity reconfigure to a lower-energy state, with the release of magnetic energy to the surroundings. Reconnection at the Earth's dayside magnetopause and in the magnetotail allows the solar wind into the magnetosphere. It begins in a smal...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/35086520

    authors: Oieroset M,Phan TD,Fujimoto M,Lin RP,Lepping RP

    更新日期:2001-07-26 00:00:00

  • Effect of natural iron fertilization on carbon sequestration in the Southern Ocean.

    abstract::The availability of iron limits primary productivity and the associated uptake of carbon over large areas of the ocean. Iron thus plays an important role in the carbon cycle, and changes in its supply to the surface ocean may have had a significant effect on atmospheric carbon dioxide concentrations over glacial-inter...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature05700

    authors: Blain S,Quéguiner B,Armand L,Belviso S,Bombled B,Bopp L,Bowie A,Brunet C,Brussaard C,Carlotti F,Christaki U,Corbière A,Durand I,Ebersbach F,Fuda JL,Garcia N,Gerringa L,Griffiths B,Guigue C,Guillerm C,Jacquet S,J

    更新日期:2007-04-26 00:00:00

  • Neuropeptide Y functions as a neuroproliferative factor.

    abstract::Neuropeptide Y (NPY) has a number of functions in mammalian physiology. Here we identify a role for NPY in promoting proliferation of postnatal neuronal precursor cells. NPY is synthesized in the postnatal olfactory epithelium by sustentacular cells, previously proposed to function only in structural support. Mice wit...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/35073601

    authors: Hansel DE,Eipper BA,Ronnett GV

    更新日期:2001-04-19 00:00:00

  • Development of a preventive vaccine for Ebola virus infection in primates.

    abstract::Outbreaks of haemorrhagic fever caused by the Ebola virus are associated with high mortality rates that are a distinguishing feature of this human pathogen. The highest lethality is associated with the Zaire subtype, one of four strains identified to date. Its rapid progression allows little opportunity to develop nat...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/35046108

    authors: Sullivan NJ,Sanchez A,Rollin PE,Yang ZY,Nabel GJ

    更新日期:2000-11-30 00:00:00

  • Identifier sequences are transcribed specifically in brain.

    abstract::'Identifier' or ID sequences are present in 62% of the RNA polymerase II and III transcripts made in vitro from brain nuclei but in fewer than 4% of the transcripts made from the nuclei of other tissues. An homologous 160-nucleotide cytoplasmic poly(A)+ RNA species, BC1, and a smaller species, BC2, are located in vivo...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/308237a0

    authors: Sutcliffe JG,Milner RJ,Gottesfeld JM,Lerner RA

    更新日期:1984-03-15 00:00:00

  • The strength and pattern of natural selection on gene expression in rice.

    abstract::Levels of gene expression underpin organismal phenotypes1,2, but the nature of selection that acts on gene expression and its role in adaptive evolution remain unknown1,2. Here we assayed gene expression in rice (Oryza sativa)3, and used phenotypic selection analysis to estimate the type and strength of selection on t...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/s41586-020-1997-2

    authors: Groen SC,Ćalić I,Joly-Lopez Z,Platts AE,Choi JY,Natividad M,Dorph K,Mauck WM 3rd,Bracken B,Cabral CLU,Kumar A,Torres RO,Satija R,Vergara G,Henry A,Franks SJ,Purugganan MD

    更新日期:2020-02-01 00:00:00

  • Fast vesicle reloading and a large pool sustain high bandwidth transmission at a central synapse.

    abstract::What limits the rate at which sensory information can be transmitted across synaptic connections in the brain? High-frequency signalling is restricted to brief bursts at many central excitatory synapses, whereas graded ribbon-type synapses can sustain release and transmit information at high rates. Here we investigate...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature04509

    authors: Saviane C,Silver RA

    更新日期:2006-02-23 00:00:00

  • Signatures of granular microstructure in dense shear flows

    abstract::Granular materials and ordinary fluids react differently to shear stresses. Rather than deforming uniformly, materials such as dry sand or cohesionless powders develop shear bands--narrow zones of large relative particle motion, with essentially rigid adjacent regions. Because shear bands mark areas of flow, material ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/35019032

    authors: Mueth DM,Debregeas GF,Karczmar GS,Eng PJ,Nagel SR,Jaeger HM

    更新日期:2000-07-27 00:00:00

  • IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex.

    abstract::Pro-inflammatory cytokines activate the transcription factor NF-kappaB by stimulating the activity of a protein kinase that phosphorylates IkappaB, an inhibitor of NF-kappaB, at sites that trigger its ubiquitination and degradation. This results in the nuclear translocation of freed NF-kappaB dimers and the activation...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/26261

    authors: Rothwarf DM,Zandi E,Natoli G,Karin M

    更新日期:1998-09-17 00:00:00

  • Osmotic stress mimics effects of vasopressin on learned behaviour.

    abstract::It has been suggested that arginine vasopressin (AVP) is involved in the retention of learned responses, in addition to its classical physiological functions of water retention and modulation of blood pressure. AVP administered subcutaneously (s.c.), intraventricularly or intracerebrally can prolong extinction of acti...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/315750a0

    authors: Koob GF,Dantzer R,Rodriguez F,Bloom FE,Le Moal M

    更新日期:1985-06-27 00:00:00

  • T cells can distinguish between allogeneic major histocompatibility complex products on different cell types.

    abstract::In the response of T cells to foreign antigens, the ligand for the T cell alpha/beta receptor is presented on a cell surface as a fragment of antigen complexed to one of the membrane molecules encoded in the major histocompatibility complex (MHC). The receptor apparently interacts via its variable elements (V beta, D ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/332840a0

    authors: Marrack P,Kappler J

    更新日期:1988-04-28 00:00:00

  • Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117.

    abstract::HIV-1 immunotherapy with a combination of first generation monoclonal antibodies was largely ineffective in pre-clinical and clinical settings and was therefore abandoned. However, recently developed single-cell-based antibody cloning methods have uncovered a new generation of far more potent broadly neutralizing anti...

    journal_title:Nature

    pub_type: 杂志文章,多中心研究

    doi:10.1038/nature14411

    authors: Caskey M,Klein F,Lorenzi JC,Seaman MS,West AP Jr,Buckley N,Kremer G,Nogueira L,Braunschweig M,Scheid JF,Horwitz JA,Shimeliovich I,Ben-Avraham S,Witmer-Pack M,Platten M,Lehmann C,Burke LA,Hawthorne T,Gorelick RJ,Walk

    更新日期:2015-06-25 00:00:00

  • Dynamics of a seafloor-spreading episode at the East Pacific Rise.

    abstract::Seafloor spreading is largely unobserved because 98 per cent of the global mid-ocean-ridge system is below the ocean surface. Our understanding of the dynamic processes that control seafloor spreading is thus inferred largely from geophysical observations of spreading events on land at Afar in East Africa and Iceland....

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature20116

    authors: Tan YJ,Tolstoy M,Waldhauser F,Wilcock WS

    更新日期:2016-12-08 00:00:00

  • Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor.

    abstract::Since the discovery that epidermal growth factor (EGF) can accelerate opening of the eyelids, the EGF receptor (EGF-R) has been extensively studied and is now considered to be a prototype tyrosine kinase receptor. Binding of EGF or of transforming growth factor-alpha (TGF-alpha) or other related factors activates the ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/376337a0

    authors: Miettinen PJ,Berger JE,Meneses J,Phung Y,Pedersen RA,Werb Z,Derynck R

    更新日期:1995-07-27 00:00:00

  • Phagosomes are competent organelles for antigen cross-presentation.

    abstract::The ability to process microbial antigens and present them at the surface of cells is an important aspect of our innate ability to clear infections. It is generally accepted that antigens in the cytoplasm are loaded in the endoplasmic reticulum and presented at the cell surface on major histocompatibility complex (MHC...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature01912

    authors: Houde M,Bertholet S,Gagnon E,Brunet S,Goyette G,Laplante A,Princiotta MF,Thibault P,Sacks D,Desjardins M

    更新日期:2003-09-25 00:00:00

  • Structure and flexibility in cortical representations of odour space.

    abstract::The cortex organizes sensory information to enable discrimination and generalization1-4. As systematic representations of chemical odour space have not yet been described in the olfactory cortex, it remains unclear how odour relationships are encoded to place chemically distinct but similar odours, such as lemon and o...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/s41586-020-2451-1

    authors: Pashkovski SL,Iurilli G,Brann D,Chicharro D,Drummey K,Franks KM,Panzeri S,Datta SR

    更新日期:2020-07-01 00:00:00

  • Evolution of RNA editing in kinetoplastid protozoa.

    abstract::The editing of RNA in trypanosomatid mitochondria involves the insertion and occasional deletion of uridine residues within coding regions of maxicircle messenger RNA transcripts. The extent to which the transcripts of homologous genes undergo editing differs in different species. In some, entire genes are edited (pan...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/368345a0

    authors: Maslov DA,Avila HA,Lake JA,Simpson L

    更新日期:1994-03-24 00:00:00

  • Baf60c is essential for function of BAF chromatin remodelling complexes in heart development.

    abstract::Tissue-specific transcription factors regulate several important aspects of embryonic development. They must function in the context of DNA assembled into the higher-order structure of chromatin. Enzymatic complexes such as the Swi/Snf-like BAF complexes remodel chromatin to allow the transcriptional machinery access ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature03071

    authors: Lickert H,Takeuchi JK,Von Both I,Walls JR,McAuliffe F,Adamson SL,Henkelman RM,Wrana JL,Rossant J,Bruneau BG

    更新日期:2004-11-04 00:00:00

  • Predicting new molecular targets for known drugs.

    abstract::Although drugs are intended to be selective, at least some bind to several physiological targets, explaining side effects and efficacy. Because many drug-target combinations exist, it would be useful to explore possible interactions computationally. Here we compared 3,665 US Food and Drug Administration (FDA)-approved...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature08506

    authors: Keiser MJ,Setola V,Irwin JJ,Laggner C,Abbas AI,Hufeisen SJ,Jensen NH,Kuijer MB,Matos RC,Tran TB,Whaley R,Glennon RA,Hert J,Thomas KL,Edwards DD,Shoichet BK,Roth BL

    更新日期:2009-11-12 00:00:00

  • A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences.

    abstract::A biologically active complementary DNA clone of a transforming gene present in a human colon carcinoma contains gene sequences of both tropomyosin and a previously unknown protein tyrosine kinase. The predicted protein (641 amino acids) encoded by this oncogene seems to have been formed by a somatic rearrangement tha...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/319743a0

    authors: Martin-Zanca D,Hughes SH,Barbacid M

    更新日期:1986-02-27 00:00:00

  • Publisher Correction: DNA damage detection in nucleosomes involves DNA register shifting.

    abstract::In this Article, in Fig. 1a, the 5' and 3' labels were reversed in the DNA sequence, and Fig. 4 was missing panel labels a-e. These errors have been corrected online. ...

    journal_title:Nature

    pub_type: 已发布勘误

    doi:10.1038/s41586-019-1343-8

    authors: Matsumoto S,Cavadini S,Bunker RD,Grand RS,Potenza A,Rabl J,Yamamoto J,Schenk AD,Schübeler D,Iwai S,Sugasawa K,Kurumizaka H,Thomä NH

    更新日期:2019-07-01 00:00:00