Cocaine- and amphetamine-regulated transcript protects synaptic structures in neurons after ischemic cerebral injury.

abstract：:The present study was undertaken in order to establish the possible involvement of melatonin in the mechanisms underlying the arginine-vasopressin (AVP) responses to physical exercise and angiotensin II (ANG II). On two mornings at least 1 week apart, normal male subjects were tested with exercise on a bicycle ergomet...

journal_title：Neuropeptides

authors： Chiodera P,Volpi R,Capretti L,Giuliani N,Maffei ML,Coiro V

更新日期：1998-04-01 00:00:00

abstract：:The role of somatostatin on inhibition of both normal and tumor cell cycle, secretion of endocrine and exocrine cells, as well as induction apoptosis is well documented. However, its effect on T cell development and thymic structure is not fully clarified. In order to investigate the influence of somatostatin in vivo ...

journal_title：Neuropeptides

authors： Petrović-Dergović DM,Rakin AK,Dimitrijević LA,Ristovski JS,Kustrimović NZ,Mićić MV

更新日期：2007-12-01 00:00:00

abstract：:The aim of the present work was to study the potential involvement of melanocortin system in the anorectic mechanism of fluoxetine, a selective serotonin reuptake inhibitors, in obese Zucker rats. Male obese Zucker (fa/fa) rats were administered fluoxetine (10 mg/kg; i.p.) daily for two weeks. The control group was gi...

journal_title：Neuropeptides

authors： Churruca I,Portillo MP,Casis L,Gutiérrez A,Macarulla MT,Echevarría E

更新日期：2008-06-01 00:00:00

abstract：:Microchemotaxis chambers were used to investigate whether one aspect of ciliary neurotrophic factor CNTF's role as a lesion factor might be to promote the initial early recruitment of macrophages, which express the signal transducing receptor components, gp130 and LIFRbeta. CNTFRalpha alone, or in combination with CNT...

journal_title：Neuropeptides

authors： Kobayashi H,Mizisin AP

更新日期：2000-12-01 00:00:00

abstract：:Immunohistochemical tests have demonstrated for the first time the presence of endothelins in the neuroendocrine cells of fish gill. We have sought co-localization of endothelins with serotonin and neuropeptides which are regarded as neuroendocrine markers of pulmonary diffuse neuroendocrine systems in higher vertebra...

journal_title：Neuropeptides

authors： Zaccone G,Mauceri A,Fasulo S,Ainis L,Lo Cascio P,Ricca MB

更新日期：1996-02-01 00:00:00

abstract：:Angiotensin I-converting enzyme (ACE) is recognized as one of the main effector molecules involved in blood pressure regulation. In the last few years some polymorphisms of ACE such as the insertion/deletion (I/D) polymorphism have been described, but their physiologic relevance is poorly understood. In addition, few ...

journal_title：Neuropeptides

authors： Almeida SS,Barros CC,Moraes MR,Russo FJ,Haro AS,Rosa TS,Alves MF,Pesquero JB,Carmona AK,Bacurau RF,Araújo RC

更新日期：2010-04-01 00:00:00

abstract：:Immune system function has been shown to be under the influence of various neuromodulators and endocrine system peptides. This in vitro study describes the stimulatory effect of thyrotropin releasing hormone (thyroliberin, TRH) on thyrotropin (TSH) release from cultured human peripheral blood monocytes. The stimulator...

journal_title：Neuropeptides

authors： Komorowski J,Stepień H,Pawlikowski M

更新日期：1993-07-01 00:00:00

abstract：:Fracture repair is a complex yet well orchestrated regenerative process involving numerous signaling and cell types including osteoblasts. Here we showed that NPY, a neurotransmitter with regulatory functions in bone homeostasis, may contribute to the post-fracture bone healing in patients with traumatic brain injury-...

journal_title：Neuropeptides

authors： Gu XC,Zhang XB,Hu B,Zi Y,Li M

更新日期：2016-12-01 00:00:00

abstract：:Both endothelins and corticotropin releasing factor (CRF) appear in capsaicin-sensitive neurons. We have investigated the effects of human endothelin-1 (ET-1) and CRF in the guinea-pig ileum longitudinal and circular preparations and sought for ways of specific antagonism. With the aid of tachyphylaxis to capsaicin (i...

journal_title：Neuropeptides

authors： Lázár Z,Benkó R,Bölcskei K,Rumbus Z,Wolf M,Holzer P,Maggi CA,Barthó L

更新日期：2003-08-01 00:00:00

abstract：:Chronic stress induces the activation of hippocampal microglia, which produces many inflammatory mediators and mediates the occurrence of depression. Two phenotypes of microglia polarization, the classical M1 and alternative M2, play important regulatory roles in neuroinflammation and are involved in the occurrence an...

journal_title：Neuropeptides

authors： Zhou S,Chen S,Xie W,Guo X,Zhao J

更新日期：2020-06-01 00:00:00

abstract：:Humanin (HN) is an endogenous 24-residue peptide. A highly potent HN derivative, S14G-HN, which has a substitution of serine 14 to glycine, reduced amyloid burden and suppressed cognitive impairment in a mouse model of Alzheimer's disease. S14G-HN also suppressed amnesia induced by a muscarinic receptor antagonist in ...

journal_title：Neuropeptides

authors： Murakami M,Nagahama M,Maruyama T,Niikura T

更新日期：2017-04-01 00:00:00

abstract：:In vivo microdialysis was employed to explore the effects of different selective non-peptides NK(1),NK(2) and NK(3) receptor antagonists on the corticotropin releasing factor (CRF)-induced release of acetylcholine (ACh) in the hippocampus of rats and guinea-pigs. In both species, the intracerebroventricular (i.c.v.) a...

journal_title：Neuropeptides

authors： Desvignes C,Rouquier L,Souilhac J,Mons G,Rodier D,Soubrié P,Steinberg R

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Chromogranin A (CgA) in plasma (P-CgA), a neuroendocrine marker of sympathetic stress, has been shown to predict mortality in medical intensive care. We hypothesized that the magnitude of CgA release would reflect stress load, and thereby injury severity in burn intensive care patients. METHODS:Fifty-one co...

journal_title：Neuropeptides

authors： Lindahl AE,Low A,Stridsberg M,Sjöberg F,Ekselius L,Gerdin B

更新日期：2013-06-01 00:00:00

abstract：:In binding assays with homogenates of the myenteric plexus-longitudinal muscle of the guinea-pig, beta-funaltrexamine is more potent at displacing mu-binding than kappa-binding. Incubation of homogenates with beta-funaltrexamine (100 or 1000 nM) for 30 min at 37 degrees C followed by repeated washing with drug-free Tr...

journal_title：Neuropeptides

authors： McKnight AT,Paterson SJ,Corbett AD,Kosterlitz HW

更新日期：1984-12-01 00:00:00

abstract：:The biological and immunological properties of insulin-like material produced by brain cells from 12 day old mice, cultured in serum-free media were examined. Differences were seen in the rate of appearance, relative amounts and behaviour on HPLC between immunoreactive and biologically active insulin-like material. Ex...

journal_title：Neuropeptides

authors： Birch NP,Christie DL,Renwick AG

更新日期：1987-05-01 00:00:00

abstract：:The neurokinin-1 (NK-1) receptor interacts with peptides that belong to the tachykinin family. NK-1 is inducible in bone marrow (BM) stroma. In neural cells, its expression is high to constitutive. Screening of three cDNA libraries indicated that this different in NK-1 expression in neural and BM cells could not be ex...

journal_title：Neuropeptides

authors： Bandari PS,Qian J,Yehia G,Seegopaul HP,Harrison JS,Gascon P,Fernandes H,Rameshwar P

更新日期：2002-02-01 00:00:00

abstract：:Neurokinin A (NKA) and substance P (SP) are often co-localized in small sensory neurons and have been suggested to subserve similar roles. We have now compared tissue levels of NKA and SP in rat cervical dorsal root ganglia with those in the central and peripheral terminations of the same neurons. We found that NKA co...

journal_title：Neuropeptides

authors： Bakhle YS,Bell C

更新日期：1995-04-01 00:00:00

abstract：:In our previous study we have identified PACAP, VIP and their receptors in rat malignant peripheral nerve sheath tumor (MPNST) cells, thus showing anti-apoptotic roles. Recently it has been shown that the tumor suppressor neurofibromin, encoded by the Neurofibromatosis type I (NF1) gene, promotes MPNST cells sensitivi...

journal_title：Neuropeptides

authors： Giunta S,Castorina A,Adorno A,Mazzone V,Carnazza ML,D'Agata V

更新日期：2010-02-01 00:00:00

abstract：:Brain extracts from 3 to 4 day old final (eighth) instar larvae of Opisina arenosella (Lepidoptera) stimulate amylase release from midgut preparations maintained in vitro. This effect of the brain extract was both time and dose dependent. The brain factor stimulating enzyme release may be a peptide as it is heat stabl...

journal_title：Neuropeptides

authors： Harshini S,Reshmi V,Sreekumar S

更新日期：2003-06-01 00:00:00

abstract：:Experiments were performed to determine whether the renal nerve mediates the renin release induced by intracerebroventricular administration of angiotensin II (ANG II), bradykinin (BK), leucine-enkephalin (Leu-ENK) and neurotensin (NT). In sham-operated rats, both ANG II and NT suppressed plasma renin activity (PRA), ...

journal_title：Neuropeptides

authors： Iwata T,Hiwada K,Kokubu T

更新日期：1985-09-01 00:00:00

abstract：:Orexins are neuropeptides that are localized to neurons in the lateral and dorsal hypothalamus but its receptors are distributed to many different regions of the central nervous system. Orexins are implicated in a variety of physiological functions including sleep regulation, energy homeostats, and stress reactions. F...

journal_title：Neuropeptides

authors： Toyama S,Shimoyama N,Shimoyama M

更新日期：2017-02-01 00:00:00

abstract：:Bombesin (BN) and its mammalian counterpart gastrin-releasing peptide act as neuroregulatory hormones and tissue-specific growth factors, and have been implicated as peripheral and central satiety-inducing agents. In the present study, the immunohistochemical expression of BN in submandibular, sublingual and parotid g...

journal_title：Neuropeptides

authors： Aalto Y,Kjörell U,Henriksson R,Franzén L,Forsgren S

更新日期：1997-04-01 00:00:00

abstract：:This study investigated the nature of the cholecystokinin-like immunoreactivity (CCKLI) in the dorsal horn of the rat spinal cord. Indeed, using the same antiserum, no variation of radioimmunoassayable CCKLI in the dorsal horn of rats treated neonatally with capsaicin could be seen, whereas the density of immunoreacti...

journal_title：Neuropeptides

authors： Zouaoui D,Benoliel JJ,Conrath M,Cesselin F

更新日期：1990-12-01 00:00:00

abstract：:The effect of the neurokinin-1 (NK1) receptor antagonist RP67580 in modulating inflammatory oedema formation has been investigated in guinea-pig skin. Oedema formation was measured over 30 min by the extravascular accumulation of intravenously-injected 125I-albumin in the anaesthetised guinea-pig. RP67580 was injected...

journal_title：Neuropeptides

authors： Wilsoncroft P,Euzger H,Brain SD

更新日期：1994-06-01 00:00:00

abstract：:Two tachykinin peptides, substance P (SP) and hemokinin-1 (HK-1), and three transient receptor potential (TRP) channels, TRPV1, TRPA1 and TRPM8, are similarly localized in the spinal dorsal horn and dorsal root ganglion, suggesting that TRP channels may be related or modulated by these tachykinin peptides. Thus, to cl...

journal_title：Neuropeptides

authors： Naono-Nakayama R,Sunakawa N,Ikeda T,Nishimori T

更新日期：2010-02-01 00:00:00

abstract：:Endothelins (ET) are a family of highly active neuropeptides with manifold influences via ET receptors (ETR) in both the peripheral and central nervous systems. We have shown previously that satellite glial cells (SGCs) in mouse trigeminal ganglia (TG) are extremely sensitive to ET-1 in evoking [Ca2+]in increase, appa...

journal_title：Neuropeptides

authors： Feldman-Goriachnik R,Hanani M

更新日期：2017-06-01 00:00:00

abstract：:Cholecystokinin (CCK) is co-localized with dopamine (DA) in mesolimbic neurons of the CNS and appears to selectively regulate the output of this system. In an attempt to characterize the nature of CCK interactions with mesolimbic DA-containing nerve terminals, we have investigated CCK regulation of [3H]DA overflow fro...

journal_title：Neuropeptides

authors： Vickroy TW,Bianchi BR

更新日期：1989-01-01 00:00:00

abstract：:The orexins (hypocretins) are lateral hypothalamic (LH) neuropeptides that have been implicated in a variety of behaviors ranging from feeding to sleep and arousal. Evidence from animal models suggests a role for orexins in reward processing and drug addiction. In the present study, we investigated the direct effect o...

journal_title：Neuropeptides

authors： Zarepour L,Fatahi Z,Sarihi A,Haghparast A

更新日期：2014-06-01 00:00:00

abstract：:After chronic treatment with morphine, the muscular rigidity mediated by opioid receptors in the striatum, was gradually replaced by stereotypic behaviour indicating an increased nigrostriatal dopaminergic activity. These results suggest that one behavioural pattern, originating in the striatum, was replaced by anothe...

journal_title：Neuropeptides

authors： Themann P,Havemann U,Kuschinsky K

更新日期：1984-12-01 00:00:00

abstract：:Utilizing a double-blind crossover design, the hormonal effects of high dose, 2 mg/kg, were compared to low dose, 0.4 mg (approx. 5 micrograms/kg), naloxone administration in physically healthy humans. A significant naloxone dose effect on plasma cortisol levels was found (p less than 0.001), but no significant effect...

journal_title：Neuropeptides

authors： Cohen MR,Cohen RM,Pickar D,Kreger D,McLellan C,Murphy DL

更新日期：1985-07-01 00:00:00