Abstract:
BACKGROUND:China is facing challenges of the shifting presentation of tuberculosis (TB) from younger to elderly due to an ageing population, longer life expectancy and reactivation disease. However, the burden of elderly TB and influence factors are not yet clear. To fill the gap, we generated a cohort study to measure the magnitude of TB incidence and associated factors among the elderly population aged 65 years and above in China. METHODS:In this cohort established in 2013 through a prevalence survey conducted in selected sites, a total of 34 076 elderlies without TB were enrolled into two-year follow-up. We used both active and passive case findings to find out all TB patients among them. The person-year (PY) incidence rates for both bacteriologically positive TB and active TB were calculated. Cox proportional regression model was performed to test effect of risk factors, and the population attributable fraction (PAF) of each risk factor contributing to incident TB among elderlies was calculated. RESULTS:Over the two-year follow-up period, a total of 215 incident active TB were identified, 62 of which were bacteriologically positive. The incidence rates for active TB and bacteriologically positive TB were 481.8 per 100 000 PY (95% CI: 417.4-546.2 per 100 000 PY) and 138.9 per 100 000 PY (95% CI: 104.4-173.5 per 100 000 PY), respectively. Incident cases detected by active case finding were significantly higher (P < 0.001). Male, non-Han nationality, previously treated TB, ex/current smoker and body mass index (BMI) < 18.5 presented as independent predictors for developing TB disease. For developing bacteriologically positive TB, the biggest contribution was from self-reported ex or current smoker (18.06%). And, for developing active TB, the biggest contribution was from non-Han nationality (35.40%), followed by male (26.80%) and age at 75 years and above (10.85%). CONCLUSIONS:Ageing population in China had a high TB incidence rate and risk to develop TB disease, implying that National TB Program (NTP) needs to prioritize for elderly. Active case finding should be applied capture more active TB cases among this particular population, especially for male, non-Han nationality, and those with identified risk factors.
journal_name
Infect Dis Povertyjournal_title
Infectious diseases of povertyauthors
Cheng J,Sun YN,Zhang CY,Yu YL,Tang LH,Peng H,Peng Y,Yao YX,Hou SY,Li JW,Zhao JM,Xia L,Xu L,Xia YY,Zhao F,Wang LX,Zhang Hdoi
10.1186/s40249-019-0614-9subject
Has Abstractpub_date
2020-01-31 00:00:00pages
13issue
1eissn
2095-5162issn
2049-9957pii
10.1186/s40249-019-0614-9journal_volume
9pub_type
杂志文章abstract:BACKGROUND:A high epilepsy prevalence has been reported in several onchocerciasis-endemic villages along the Mbam and Sanaga river valleys in Cameroon, including Bilomo and Kelleng. We sought to determine the prevalence of epilepsy in these two villages following more than 13 years of community-directed treatment with ...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-018-0497-1
更新日期:2018-12-03 00:00:00
abstract::Despite increased international efforts to control schistosomiasis using preventive chemotherapy, several challenges still exist in reaching the target populations. Until recently, preschool-aged children had been excluded from the recommended target population for mass drug administration, i.e. primary school childre...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章,评审
doi:10.1186/s40249-017-0300-8
更新日期:2017-04-07 00:00:00
abstract:CORRECTION:After publication of this article [1] it came to our attention that the affiliation of Jun Chen and Hong-zhou Lu were incorrectly shown.Jun Chen's affiliation should have been given as Department of Infectious Diseases, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.Hong-zhou Lu sh...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章,已发布勘误
doi:10.1186/s40249-017-0376-1
更新日期:2017-11-23 00:00:00
abstract::Unfortunately, the original article [1] contained some errors. The table title of Tables 4, 5, 6, 7 were interchanged by mistake and displayed incorrectly in the article. The correct table titles of Tables 4, 5, 6, 7 can be found below. ...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章,已发布勘误
doi:10.1186/s40249-018-0415-6
更新日期:2018-04-20 00:00:00
abstract::In the past five months, success in control the national epidemic of coronavirus disease 2019 (COVID-19) has been witnessed in China. The implementation of public health measures accounts for the success which include different interventions in the early or later stages of the outbreak. It is clear that although not a...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-020-00759-3
更新日期:2020-10-12 00:00:00
abstract:BACKGROUND:Brucellosis is a major public health issue in China, while its temporal and spatial distribution have not been studied in depth. This study aims to better understand the epidemiology of brucellosis in the mainland of China, by investigating the human, temporal and spatial distribution and clustering characte...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-020-00754-8
更新日期:2020-10-13 00:00:00
abstract:BACKGROUND:The coronavirus disease 2019 (COVID-19) epidemic met coincidentally with massive migration before Lunar New Year in China in early 2020. This study is to investigate the relationship between the massive migration and the coronavirus disease 2019 (COVID-19) epidemic in China. METHODS:The epidemic data betwee...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-020-00722-2
更新日期:2020-08-10 00:00:00
abstract:BACKGROUND:Hand, foot, and mouth disease (HFMD) has become an emerging infectious disease in China in the last decade. There has been evidence that meteorological factors can influence the HFMD incidence, and understanding the mechanisms can help prevent and control HFMD. METHODS:HFMD incidence data and meteorological...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-018-0388-5
更新日期:2018-01-31 00:00:00
abstract::Infectious diseases of poverty, a collective term coined for infections known to be particularly prevalent amongst poor populations, is increasingly used for neglected tropical diseases (NTDs) with special transmission routes, such as depending on vectors and/or intermediate hosts. The journal Infectious Diseases of P...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/2049-9957-1-1
更新日期:2012-10-25 00:00:00
abstract:BACKGROUND:Following the West Africa Ebola virus disease (EVD) outbreak (2013-2016), WHO developed a preparedness checklist for its member states. This checklist is currently being applied for the first time on a large and systematic scale to prepare for the cross border importation of the ongoing EVD outbreak in the D...
journal_title:Infectious diseases of poverty
pub_type: 信件
doi:10.1186/s40249-020-00657-8
更新日期:2020-04-21 00:00:00
abstract::Schistosomiasis is an important zoonotic parasitic disease that causes serious harms to humans and animals. Surveillance and diagnosis play key roles in schistosomiasis control, however, current techniques for surveillance and diagnosis of the disease have limitations. As genome data for parasites are increasing, nove...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章,评审
doi:10.1186/s40249-016-0116-y
更新日期:2016-03-30 00:00:00
abstract::Ecohealth is a comprehensive approach to understanding health at its human, animal and environmental interface in a socio-ecological systems context. This approach was introduced widely in Southeast Asia (SEA) by the Canadian International Development Research Centre (IDRC) in the late 2000s. Aimed at addressing the p...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/2049-9957-4-5
更新日期:2015-01-29 00:00:00
abstract::Enabling innovation and access to health technologies remains a key strategy in combating infectious diseases in low- and middle-income countries (LMICs). However, a gulf between paying markets and the endemicity of such diseases has contributed to the dearth of R&D in meeting these public health needs. While the phar...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/2049-9957-1-2
更新日期:2012-10-25 00:00:00
abstract:BACKGROUND:Echinococcosis is a parasitic zoonosis caused by Echinococcus larvae parasitism causing high mortality. The Tibetan Region of Sichuan Province is a high prevalence area for echinococcosis in China. Understanding the geographic distribution pattern is necessary for precise control and prevention. In this stud...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-018-0486-4
更新日期:2018-11-02 00:00:00
abstract:BACKGROUND:The pandemic of the coronavirus disease 2019 (COVID-19) has caused substantial disruptions to health services in the low and middle-income countries with a high burden of other diseases, such as malaria in sub-Saharan Africa. The aim of this study is to assess the impact of COVID-19 pandemic on malaria trans...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-020-00788-y
更新日期:2021-01-07 00:00:00
abstract:BACKGROUND:Aedes borne viral diseases, notably dengue, are increasingly reported in Cameroon with Aedes aegypti being a major vector. Data on insecticide resistance of this vector and underlying mechanisms needed for outbreak preparedness remain scarce in Cameroon. Here, we present the nationwide distribution of insect...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-020-00769-1
更新日期:2020-11-02 00:00:00
abstract:BACKGROUND:As part of an ongoing program that aims to use early detection and timely treatment to improve the control of echinococcosis, especially in younger age groups, we undertook a series of active surveys among Qinghai-Tibetan children in the Qinghai Province of Northwestern China in 2011 and 2012. The significan...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-018-0455-y
更新日期:2018-07-12 00:00:00
abstract::Brucellosis is one of the most widespread zoonoses in the world caused by several species of the genus Brucella. The disease, eradicated in many developed countries, is a re-emerging neglected zoonosis endemic in several zones especially in the Mediterranean region, impacting on human health and livestock production. ...
journal_title:Infectious diseases of poverty
pub_type: 历史文章,杂志文章,meta分析
doi:10.1186/s40249-015-0086-5
更新日期:2015-12-22 00:00:00
abstract:BACKGROUND:Epidermal parasitic skin diseases (EPSD) occur in most countries and cause a considerable health and economic burden, particularly in the tropics and subtropics. The aim of this study was to assess and analyse peer-reviewed literature on EPSD in humans. The results of this study serve as an indicator of the ...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-018-0456-x
更新日期:2018-08-06 00:00:00
abstract:BACKGROUND:The prevalence of infection with Toxoplasma gondii (T. gondii) in humans has been increasing in China due to the growing number of cats in the country. Hand, foot and mouth disease (HFMD) is a serious public health issue in China and still one of the leading causes of child mortality. However, little is know...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-015-0088-3
更新日期:2015-12-10 00:00:00
abstract:BACKGROUND:The livestock industry plays a vital role in the economy of Nigeria. It serves as a major source of income and livelihood for majority of Nigerians who are rural settlers and contributes about 5.2% to the National Gross Domestic Product (GDP). Helminths however, cause economic losses due to reductions in mil...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章,meta分析
doi:10.1186/s40249-018-0438-z
更新日期:2018-05-29 00:00:00
abstract:BACKGROUND:Echinococcosis has a worldwide geographical distribution with endemic foci on every inhabited continent. Due to the frequent outbreaks in different parts of Pakistan in the recent past, echinococcosis is being described as a neglected tropical disease and is considered one of the most neglected parasitic dis...
journal_title:Infectious diseases of poverty
pub_type: 信件
doi:10.1186/s40249-017-0309-z
更新日期:2017-07-03 00:00:00
abstract::Mechanisms and outcomes of host-parasite interactions during malaria co-infections with gastrointestinal helminths are reasonably understood. In contrast, very little is known about such mechanisms in cases of malaria co-infections with tissue-dwelling parasites. This is lack of knowledge is exacerbated by misdiagnosi...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s40249-015-0070-0
更新日期:2015-08-29 00:00:00
abstract:BACKGROUND:The damage inflicted by the coronavirus diseases 2019 (COVID-19) pandemic upon humanity is and will continue to be considerable. Unprecedented progress made in global health over the past 20 years has reverted and economic growth has already evaporated, giving rise to a global recession, the likes of which w...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章,评审
doi:10.1186/s40249-020-00790-4
更新日期:2021-01-04 00:00:00
abstract:BACKGROUND:Interventions are currently being used against 'infectious diseases of poverty', which remain highly debilitating and deadly in most endemic countries, especially malaria, schistosomiasis, echinococcosis and African sleeping sickness. However, major limitations of current 'traditional' methods for diagnosis ...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-017-0344-9
更新日期:2017-10-02 00:00:00
abstract:BACKGROUND:Zooprophylaxis is the use of wild or domestic animals, which are not the reservoir host of a given disease, to divert the blood-seeking malaria vectors from human hosts. In this paper, we systematically reviewed zooprophylaxis to assess its efficacy as a malaria control strategy and to evaluate the possible ...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章,评审
doi:10.1186/s40249-017-0366-3
更新日期:2017-10-25 00:00:00
abstract:BACKGROUND:Access to clean and safe drinking water that is free from pathogenic protozoan parasites, especially Cryptosporidium parvum and Giardia lamblia that cause gastrointestinal illness in humans, is still an issue in Southeast Asia (SEA). This study is the first attempt to detect the aforementioned protozoan para...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-016-0095-z
更新日期:2016-01-13 00:00:00
abstract:BACKGROUND:National tuberculosis (TB) programs increasingly engage with international non-governmental organizations (INGOs), especially to provide TB care in complex settings where community involvement might be required. In Myanmar, however, there is limited data on how such INGO community-based programs are organize...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-017-0285-3
更新日期:2017-03-24 00:00:00
abstract:BACKGROUND:Recently, several epidemiological studies performed in Onchocerca volvulus-endemic regions have suggested that onchocerciasis-associated epilepsy (OAE) may constitute an important but neglected public health problem in many countries where onchocerciasis is still endemic. MAIN TEXT:On October 12-14th 2017, ...
journal_title:Infectious diseases of poverty
pub_type: 社论
doi:10.1186/s40249-018-0400-0
更新日期:2018-03-22 00:00:00
abstract:BACKGROUND:Before 2014 (the year of closure of the two largest needle exchange programs in Hungary, which halved the number of available syringes in the country despite increased injecting risk practices) no HIV was reportedly acquired in Hungary among people who inject drugs (PWIDs) who were not also men who had sex w...
journal_title:Infectious diseases of poverty
pub_type: 杂志文章
doi:10.1186/s40249-017-0360-9
更新日期:2017-10-11 00:00:00