Abstract:
:Delay embedding-a method for reconstructing dynamical systems by delay coordinates-is widely used to forecast nonlinear time series as a model-free approach. When multivariate time series are observed, several existing frameworks can be applied to yield a single forecast combining multiple forecasts derived from various embeddings. However, the performance of these frameworks is not always satisfactory because they randomly select embeddings or use brute force and do not consider the diversity of the embeddings to combine. Herein, we develop a forecasting framework that overcomes these existing problems. The framework exploits various "suboptimal embeddings" obtained by minimizing the in-sample error via combinatorial optimization. The framework achieves the best results among existing frameworks for sample toy datasets and a real-world flood dataset. We show that the framework is applicable to a wide range of data lengths and dimensions. Therefore, the framework can be applied to various fields such as neuroscience, ecology, finance, fluid dynamics, weather, and disaster prevention.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Okuno S,Aihara K,Hirata Ydoi
10.1038/s41598-019-57255-4subject
Has Abstractpub_date
2020-01-20 00:00:00pages
664issue
1issn
2045-2322pii
10.1038/s41598-019-57255-4journal_volume
10pub_type
杂志文章abstract::Cellular membrane distortion invokes variations in cellular physiology. However, lack of an appropriate system to control the stress and facilitate molecular analyses has hampered progress of relevant studies. In this study, a microfluidic system that finely manipulates membrane distortion of Chlamydomonas reinhardtii...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep04675
更新日期:2014-04-14 00:00:00
abstract::Artificial grasslands play a role in carbon storage on the Qinghai-Tibetan Plateau. The artificial grasslands exhibit decreased proportions of graminate and increased species richness with age. However, the effect of the graminate proportions and species richness on ecosystem C stocks in artificial grasslands have not...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40307
更新日期:2017-01-09 00:00:00
abstract::Antigen-presenting cells including dendritic cells (DCs) express mannan receptors (MR) on their surface, which can be exploited in cancer therapy by designing immune-stimulatory viruses coated with mannan-modified capsids that then bind to DCs and initiate a potent immune response. Although the combination of anti-ang...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep11275
更新日期:2015-06-18 00:00:00
abstract::Mucus is responsible for controlling transport and barrier function in biological systems, and its properties can be significantly affected by compositional and environmental changes. In this study, the impacts of pH and CaCl2 were examined on the solution-to-gel transition of mucin, the primary structural component o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65392-4
更新日期:2020-05-29 00:00:00
abstract::This study aims to identify a panel of blood-cell neuroplasticity-related genes expressed following environmental enrichment stimulation (EE). The Drug detection (DD) training course was an excellent model for the study of EE in the working dog. This research is divided into two experimental trials. In the First Trial...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43402-4
更新日期:2019-05-06 00:00:00
abstract::Activated coke (AC) has great potential in the field of low-temperature NO removal (DeNOx), especially the branch prepared by blending modification. In this study, the AC-based pyrolusite and/or titanium ore blended catalysts were prepared and applied for DeNOx. The results show blending pyrolusite and titanium ore pr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76592-3
更新日期:2020-11-10 00:00:00
abstract::Cell competition is a cell-cell interaction by which a cell compares its fitness to that of neighboring cells. The cell with the relatively lower fitness level is the "loser" and actively eliminated, while the cell with the relatively higher fitness level is the "winner" and survives. Recent studies have shown that ce...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28383
更新日期:2016-06-21 00:00:00
abstract::Large amounts of anthropogenic CO2 in the atmosphere are taken up by the ocean, which leads to 'ocean acidification' (OA). In addition, the increasing application of nanoparticles inevitably leads to their increased release into the aquatic environment. However, the impact of OA on the bioaccumulation of nanoparticles...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40047-1
更新日期:2019-03-05 00:00:00
abstract::Excessive Zn2+ causes brain damage via promoting ROS generation. Here we investigated the role of ROS-sensitive TRPM2 channel in H2O2/Zn2+-induced Ca2+ signalling and cell death in microglial cells. H2O2/Zn2+ induced concentration-dependent increases in cytosolic Ca2+ concentration ([Ca2+]c), which was inhibited by PJ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45032
更新日期:2017-03-21 00:00:00
abstract::Interactions of high-frequency radio waves (RF) with biological tissues are currently being investigated as a therapeutic platform for non-invasive cancer hyperthermia therapy. RF delivers thermal energy into tissues, which increases intra-tumoral drug perfusion and blood-flow. Herein, we describe an optical-based met...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43961
更新日期:2017-03-13 00:00:00
abstract::Alternations in the p53 regulatory network may render cancer cells resistant to the radiation-induced apoptosis. In this theoretical study we search for the best protocols combining targeted therapy with radiation to treat cancers with wild-type p53, but having downregulated expression of PTEN or overexpression of Wip...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-69380-6
更新日期:2020-07-28 00:00:00
abstract::Pupillary light reflex (PLR) is an involuntary response where the pupil size changes with luminance. Studies have shown that PLR response was altered in children with autism spectrum disorders (ASDs) and other neurological disorders. However, PLR in infants and toddlers is still understudied. We conducted a longitudin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58254-6
更新日期:2020-01-27 00:00:00
abstract::We engineered a transdermal neuromodulation approach that targets peripheral (cranial and spinal) nerves and utilizes their afferent pathways as signaling conduits to influence brain function. We investigated the effects of this transdermal electrical neurosignaling (TEN) method on sympathetic physiology under differe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13865
更新日期:2015-09-10 00:00:00
abstract::Parkinson's disease (PD) is a neurodegenerative disorder characterised by motor abnormalities. Many non-demented patients with PD have cognitive impairment especially in executive functions. Using magnetoencephalographic (MEG) recording combined with event-related desynchronisation/synchronisation (ERD/ERS) analysis, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43762-x
更新日期:2019-05-10 00:00:00
abstract::Uncertainties over future climatic conditions pose significant challenges when selecting appropriate conservation strategies for heritage sites. Choosing effective strategies is especially important for earthen heritage sites located in dryland regions, as many are experiencing rapid environmentally-driven deteriorati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73456-8
更新日期:2020-10-02 00:00:00
abstract::Slow disintegration and poor solubility are common problems facing the dispersible tablets of Traditional Chinese Medicine (TCM). In an early study, the research group found that co-grinding of extracts and silica could achieve a rapid disintegration effect, though the mechanism of this effect was not thoroughly eluci...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28734-x
更新日期:2018-07-09 00:00:00
abstract::Accumulating evidence implies that both AKT1 and GABAA receptor (GABAAR) subunit genes are involved in schizophrenia pathogenesis. Activated Akt promotes GABAergic neuron differentiation and increases GABAAR expression on the plasma membrane. To elucidate the role of Akt1 in modulating GABAergic functions and schizoph...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33095
更新日期:2016-09-12 00:00:00
abstract::Rhizomorphic lycopsids are the land plant group that includes the first giant trees to grow on Earth and extant species in the genus Isoetes. Two mutually exclusive hypotheses account for the evolution of terminal rooting axes called rootlets among the rhizomorphic lycopsids. One hypothesis states that rootlets are tr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-78171-y
更新日期:2020-12-09 00:00:00
abstract::Ebola virus (EBOV), isolate Makona, was the causative agent of the West African epidemic devastating predominantly Guinea, Liberia and Sierra Leone from 2013-2016. While several experimental vaccine and treatment approaches have been accelerated through human clinical trials, there is still no approved countermeasure ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-19041-y
更新日期:2018-01-16 00:00:00
abstract::Copy Number Variants (CNVs) are a class of structural variations of DNA. Germline CNVs are known to confer disease susceptibility, but their role in breast cancer warrants further investigations. We hypothesized that breast cancer associated germline CNVs contribute to disease risk through gene dosage or other post-tr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25801-1
更新日期:2018-05-14 00:00:00
abstract::Atomic hydrogen exists ubiquitously in graphene materials made by chemical methods. Yet determining the effect of hydrogen on the electrochemical performance of graphene remains a significant challenge. Here we report the experimental observations of high rate capacity in hydrogen-treated 3-dimensional (3D) graphene n...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16190
更新日期:2015-11-05 00:00:00
abstract::The current theories of antimalarial mechanism of artemisinin are inadequate to fully explain the observed effects. In our study, "organism-like" formation of Schistosoma hemozoin granules by attaching to and utilizing erythrocytes to form new ones was observed. This indicates that heme iron is transferred from erythr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34463
更新日期:2016-10-03 00:00:00
abstract::Human mesenchymal stem cells (hMSCs) are widely used in regenerative medicine. In some applications, they must survive under low nutrient conditions engendered by avascularity. Strategies to improve hMSCs survival may be of high relevance in tissue engineering. Carnitine palmitoyltransferase 1 C (CPT1C) is a pseudoenz...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25485-7
更新日期:2018-05-03 00:00:00
abstract::In this work, a novel technique to create positive-negative tunable liquid crystal lenses is proposed and experimentally demonstrated. This structure is based on two main elements, a transmission line acting as a voltage divider and concentric electrodes that distribute the voltage homogeneously across the active area...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67141-z
更新日期:2020-06-23 00:00:00
abstract::Ceramide is one of the most important intercellular components responsible for the barrier and moisture retention functions of the skin. Because of the risks involved with using products of animal origin and the low productivity of plants, the availability of ceramides is currently limited. In this study, we successfu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16319
更新日期:2015-11-17 00:00:00
abstract::Identification of low-abundance, low-molecular-weight native peptides using non-tryptic plasma has long remained an unmet challenge, leaving potential bioactive/biomarker peptides undiscovered. We have succeeded in efficiently removing high-abundance plasma proteins to enrich and comprehensively identify low-molecular...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79353-4
更新日期:2021-01-13 00:00:00
abstract::Selective amygdalohippocampectomy is an effective treatment for patients with therapy-refractory temporal lobe epilepsy but may cause visual field defect (VFD). Here, we aimed to describe tissue-specific pre- and postoperative imaging correlates of the VFD severity using whole-brain analyses from voxel- to network-lev...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80751-x
更新日期:2021-01-14 00:00:00
abstract::Thirty-nine UK adapted wheat cultivars dating from between 1790 and 2012 were grown in replicated randomised field trials for three years, milled, and white flour analysed for the contents of dietary fibre components (arabinoxylan and β-glucan) and polar metabolites (sugars, amino acids, organic acids, choline and bet...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62777-3
更新日期:2020-04-03 00:00:00
abstract::The brain-derived neurotrophic factor BDNF plays a critical role in neuronal development and the induction of L-LTP at glutamatergic synapses in several brain regions. However, the cellular and molecular mechanisms underlying these BDNF effects have not been firmly established. Using in vitro cultures of cortical neur...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14778
更新日期:2015-10-06 00:00:00
abstract::Cyanobacteria are attractive microbial hosts for production of chemicals using light and CO2. However, their low productivity of chemicals is a major challenge for commercial applications. This is mostly due to their relatively slow growth rate and carbon partitioning toward biomass rather than products. Many cyanobac...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-57319-5
更新日期:2020-01-15 00:00:00