The effect of a mentally fatiguing task on postural balance control in young and older women.

abstract：:Exercise training has been associated with the attenuation of cardiovascular impairment after menopause. This study aimed to compare central and peripheral blood pressure and aortic pulse wave reflection in sedentary and trained (aerobic exercise in the water) hypertensive postmenopausal women. Hypertensive postmenopa...

journal_title：Experimental gerontology

authors： de Andrade Barboza C,Moura EG,Ministro G,Castaño JB,Silva Santos GC,Dias Junior G,Moreno Junior H,Rodrigues B

更新日期：2021-01-01 00:00:00

abstract：:Diet is the most variable aspect of life history, as most individuals have a large diversity of food choices, varying in the type and amount that they ingest. In the short-term, diet can affect metabolism and energy levels. However, in the long run, the net deficiency or excess of calories from diet can influence the ...

journal_title：Experimental gerontology

authors： Yen CA,Curran SP

更新日期：2016-12-15 00:00:00

abstract：OBJECTIVE:To assess the effect of genetic and non-genetic factors on indicators derived from waist circumference (WC) and body mass index (BMI) as well as inter-indicator differences in risk assessment age-related diseases including diabetes mellitus, coronary heart disease and liver cancer. METHODS:Height, weight and...

journal_title：Experimental gerontology

authors： Xin G,Shong L,Hui L

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Epidemiological and objective studies report an association between sedentary time and lower risk of the metabolic syndrome (MetS) and its risk factors in young and middle-age adults. To date, there is a lack of objective data on the association between sedentary time and MetS among older adults. METHODS:Th...

journal_title：Experimental gerontology

authors： Mankowski RT,Aubertin-Leheudre M,Beavers DP,Botoseneanu A,Buford TW,Church T,Glynn NW,King AC,Liu C,Manini TM,Marsh AP,McDermott M,Nocera JR,Pahor M,Strotmeyer ES,Anton SD,LIFE Research Group.

更新日期：2015-10-01 00:00:00

abstract：:Forkhead box O 3a (FoxO3a) has been known to link with aging process and senescence. In this study, we investigated the age-related changes of FoxO3a in the gerbil hippocampus using immunohistochemistry and western blot analysis. In the postnatal month 3 (PM 3) group, FoxO3a immunoreactivity was well detected in pyram...

journal_title：Experimental gerontology

authors： Park JH,Lee CH,Yoo KY,Choi JH,Hwang IK,Lee JY,Kang IJ,Won MH

更新日期：2011-10-01 00:00:00

abstract：:In the central nervous system, the degree of decline in memory retrieval along the aging process depends on the quantity and quality of the stimuli received during lifetime. The cholinergic system modulates long-term potentiation and, therefore, memory processing. This study evaluated the spatial memory, the synaptic ...

journal_title：Experimental gerontology

authors： Baraldi T,Schöwe NM,Balthazar J,Monteiro-Silva KC,Albuquerque MS,Buck HS,Viel TA

更新日期：2013-08-01 00:00:00

abstract：:Senescence, a deteriorative process that increases the probability of death of an organism with increasing chronological age, has been found in all metazoans where careful studies have been carried out. There has been much controversy, however, about the potential immortality of hydra, a solitary freshwater member of ...

journal_title：Experimental gerontology

authors： Martínez DE

更新日期：1998-05-01 00:00:00

abstract：:The mechanisms responsible for age-associated hearing loss are still incompletely characterized. In this study, we used a murine model of age-dependent hearing loss and evaluated whether this condition is associated with vascular modifications of the structures of the inner ear. We used old C57BL/6J mice that are affe...

journal_title：Experimental gerontology

authors： Picciotti P,Torsello A,Wolf FI,Paludetti G,Gaetani E,Pola R

更新日期：2004-08-01 00:00:00

abstract：:The A3243G mutation, one of the changes of human mitochondrial DNA (mtDNA) that accumulates in cells during aging, is a useful marker for investigating the aging of cells. We measured the mutation level of the mtDNA A3243G mutation using DNAs from two different tissues (esophageal epithelium and myocardium) from advan...

journal_title：Experimental gerontology

authors： Harihara S,Nakamura K,Takubo K,Takeuchi F

更新日期：2002-07-01 00:00:00

abstract：:The Tokyo Metropolitan Institute of Gerontology (TMIG) celebrates its 30th anniversary in 2002. Since its establishment, TMIG has been carrying out inter-disciplinary research on aging as a core institute in Japan and functions as a knowledge bank and a source for capable researchers of gerontology. The proportion of ...

journal_title：Experimental gerontology

authors： Suzuki K

更新日期：2002-12-01 00:00:00

abstract：:While influenza immunization significantly reduces the risk of pneumonia and associated deaths, vaccination of elderly only affords 30-50% protection against influenza disease. The purpose of this study was to: (1) evaluate the consistency of immune responses across multiple years in young and elderly; (2) determine t...

journal_title：Experimental gerontology

authors： Murasko DM,Bernstein ED,Gardner EM,Gross P,Munk G,Dran S,Abrutyn E

更新日期：2002-01-01 00:00:00

abstract：:In this study we report the identification of FAH domain containing protein 1 (FAHD1), a recently described member of the fumarylacetoacetate hydrolase (FAH) superfamily of metabolic enzymes, as a novel player in the regulation of cellular senescence. FAHD1 was found in a proteomic screen searching for mitochondrial p...

journal_title：Experimental gerontology

authors： Petit M,Koziel R,Etemad S,Pircher H,Jansen-Dürr P

更新日期：2017-06-01 00:00:00

abstract：:Based on evidence that human diploid fibroblasts (HDF) from the Werner syndrome (WS) of premature aging might overexpress an inhibitor of DNA synthesis (IDS), we prepared a eukaryotic cDNA expression library from WS mRNA and tested it for IDS activity in a transient assay. Two of six WS cDNA pools tested gave IDS acti...

journal_title：Experimental gerontology

authors： Goldstein S,Murano S,Benes H,Moerman EJ,Jones RA,Thweatt R,Shmookler Reis RJ,Howard BH

更新日期：1989-01-01 00:00:00

abstract：:Alpha-synuclein (α-Syn) accumulation is significantly correlated with motor deficits and mitochondrial dysfunction in Parkinson's disease (PD), but the molecular mechanism underlying its pathogenesis is unclear. In this study, we investigated the effects of treadmill exercise on motor deficits and mitochondrial dysfun...

journal_title：Experimental gerontology

authors： Koo JH,Cho JY,Lee UB

更新日期：2017-03-01 00:00:00

abstract：:Studies have suggested that older individuals are more fatigable than young adults when power loss, measured during single-joint contractions, is considered the fatigue index; however, age-related differences in fatigue considering power measurements during multi-joint movements (e.g., cycling) have not been fully elu...

journal_title：Experimental gerontology

authors： Krüger RL,Aboodarda SJ,Jaimes LM,Vaz MA,Samozino P,Millet GY

更新日期：2020-05-01 00:00:00

abstract：:Age-related declines in human skeletal muscle performance may be caused, in part, by decreased responsivity of muscle fibers to calcium (Ca2+). This study examined the contractile properties of single vastus lateralis muscle fibers with various myosin heavy chain (MHC) isoforms (I, I/IIA, IIA and IIAX) across a range ...

journal_title：Experimental gerontology

authors： Straight CR,Ades PA,Toth MJ,Miller MS

更新日期：2018-02-01 00:00:00

abstract：:Proteomic analysis is defined as the characterization of the entire set of proteins encoded by a genome. Two-dimensional (2D) electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) are key technologies used in proteomic analysis to gain information about protein...

journal_title：Experimental gerontology

authors： Kim CH,Park DU,Chung AS,Zou Y,Jung KJ,Sung BK,Yu BP,Chung HY

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVES:1) To determine if there was a practice effect associated with walk tests performed by frail older adults with and without dementia, 2) to examine the role of systematic cueing in the walk tests for those with dementia, and 3) to make recommendations to testing protocols of the walk tests for frail older adu...

journal_title：Experimental gerontology

authors： Chan WLS,Pin TW

更新日期：2019-09-01 00:00:00

abstract：:While it may be possible to employ panels of molecular parameters which correlate with senescence in vivo or in vitro, in a manner analogous to the use of mutagenesis assays for economic carcinogen screening, such an endeavor would at present be impeded by the absence of a clear mechanistic rationale for focusing on p...

journal_title：Experimental gerontology

authors： Shmookler Reis RJ

更新日期：1988-01-01 00:00:00

abstract：:The TOR kinase pathway is central in modulating aging in a variety of animal models. The target of rapamycin (TOR) integrates a complex network of signals from growth conditions, nutrient availability, energy status, and physiological stresses and matches an organism's growth rate to the resource environment. Importan...

journal_title：Experimental gerontology

authors： Snell TW,Johnston RK,Rabeneck B,Zipperer C,Teat S

更新日期：2014-04-01 00:00:00

abstract：:The immune response declines with age. This decline correlates with thymic involution and involves primarily a loss in T-cell function, whereas humoral immunity is more variably affected. In the current experiments we have measured immunoglobulin synthesis in vitro after mitogen stimulation, and specific antibody resp...

journal_title：Experimental gerontology

authors： Ershler WB,Robbins DL,Moore AL,Hebert JC

更新日期：1986-01-01 00:00:00

abstract：:The CG9940 gene, which encodes the NAD(+) synthase protein in Drosophila, is conserved in human, zebra fish, and mosquito. NAD(+) synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD(+)) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic a...

journal_title：Experimental gerontology

authors： Wen DT,Zheng L,Ni L,Wang H,Feng Y,Zhang M

更新日期：2016-10-01 00:00:00

abstract：:Androgen levels decrease with aging in men. Androgen deficiency in elderly men may lead to asthenia, decrease in muscle mass, osteoporosis, decrease in sexual activity, and, in some cases, changes in mood and cognitive function. Combination of these factors may result in impaired quality of life in the elderly male. A...

journal_title：Experimental gerontology

authors： Swerdloff RS,Wang C

更新日期：1993-07-01 00:00:00

abstract：:Changes associated with the age-related decline of physiological functions, and their relation with mortality rates, are thoroughly being investigated in the aging research field. We used the Mediterranean fruit fly Ceratitis capitata, largely studied by biodemographers, as a model for functional senescence studies. T...

journal_title：Experimental gerontology

authors： Pujol-Lereis LM,Rabossi A,Quesada-Allué LA

更新日期：2012-06-01 00:00:00

abstract：:A summary of the Eleventh International Symposium on the Neurobiology and Neuroendocrinology of Aging that was held in July 29-August 3 in Bregenz, Austria, is presented. Sixteen of the speakers who presented at the conference submitted review papers covering the topic of their presentation as well as an overview of t...

journal_title：Experimental gerontology

authors： Brown-Borg HM,Borg KE

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:To date studies evaluating the relation between circulating aldosterone levels and mortality in elderly female individuals are lacking. We therefore aimed to assess the relationship between circulating aldosterone levels and mortality in a population-based cohort study of female nursing home residents. METH...

journal_title：Experimental gerontology

authors： Tomaschitz A,Pilz S,Pieske B,Ritz E,März W,Meinitzer A,Dobnig H,Amrein K,Kienreich K,Verheyen N,Kraigher-Krainer E,Drechsler C,Colantonio C,Wagner D,Fahrleitner-Pammer A

更新日期：2013-03-01 00:00:00

abstract：:Aging is associated with diminished regenerative capacity and increased risk of chronic diseases. There is now compelling evidence suggests that aging process is reversible. Besides metabolic modification and systematic factors, both senescence elimination and cellular reprogramming showed beneficial effects on tissue...

journal_title：Experimental gerontology

authors： Chiche A,Chen C,Li H

更新日期：2020-09-01 00:00:00

abstract：:Natural killer (NK) cells play an important role in controlling several viral diseases. Our previous studies demonstrated an age-dependent susceptibility to mousepox due to defective NK cell responses and trafficking. However, the mechanisms that underlie the age-related impairment in NK cell migration have yet to be ...

journal_title：Experimental gerontology

authors： Duan X,Lu J,Wang H,Liu X,Wang J,Zhou K,Jiang W,Wang Y,Fang M

更新日期：2017-10-01 00:00:00

abstract：:The dependent elderly are widely considered to be at higher risk of nutritional problems. Suboptimal micronutrient intake might put the elderly, especially those living in nursing homes, at high risk of morbidity. So far, no public authority, except for the Israel Ministry of Health, has issued particular recommendati...

journal_title：Experimental gerontology

authors： Tal S,Stern F,Polyak Z,Ichelzon I,Dror Y

更新日期：2016-11-01 00:00:00

abstract：:Mitochondrial DNA 5178 adenine/cytosine (mt5178 A/C) polymorphism is one of the longevity-associated mitochondrial DNA polymorphisms. The frequency of the mt5178A genotype is significantly higher in Japanese centenarians than in the general population. We previously reported that serum high-density lipoprotein cholest...

journal_title：Experimental gerontology

authors： Kokaze A,Ishikawa M,Matsunaga N,Yoshida M,Sekine Y,Sekiguchi K,Satoh M,Harada M,Teruya K,Takeda N,Uchida Y,Tsunoda T,Takashima Y

更新日期：2003-10-01 00:00:00