Printability study of metal ion crosslinked PEG-catechol based inks.

abstract：:Calcified cartilage regeneration plays an important role in successful osteochondral repair, since it provides a biological and mechanical transition from the unmineralized cartilage at the articulating surface to the underlying mineralized bone. To biomimic native calcified cartilage in engineered constructs, here we...

journal_title：Biofabrication

authors： You F,Chen X,Cooper DML,Chang T,Eames BF

更新日期：2018-12-27 00:00:00

abstract：:This paper presents a novel continuous tool-path planning methodology for hollowed scaffold fabrication in tissue engineering. A new functionally gradient porous architecture is proposed with a continuous material deposition planning scheme. A controllable variational pore size and hence the porosity have been achieve...

journal_title：Biofabrication

authors： Khoda AK,Ozbolat IT,Koc B

更新日期：2011-09-01 00:00:00

abstract：:In clinical islet transplantation, allogeneic islets of Langerhans are transplanted into the portal vein of patients with type 1 diabetes, enabling the restoration of normoglycemia. After intra-hepatic transplantation several factors are involved in the decay in islet mass and function mainly caused by an immediate bl...

journal_title：Biofabrication

authors： Marchioli G,van Gurp L,van Krieken PP,Stamatialis D,Engelse M,van Blitterswijk CA,Karperien MB,de Koning E,Alblas J,Moroni L,van Apeldoorn AA

更新日期：2015-05-28 00:00:00

abstract：:In the past few decades, 3D printing has played a significant role in fabricating scaffolds with consistent, complex structure that meet patient-specific needs in future clinical applications. Although many studies have contributed to this emerging field of additive manufacturing, which includes material development a...

journal_title：Biofabrication

authors： Guo T,Holzberg TR,Lim CG,Gao F,Gargava A,Trachtenberg JE,Mikos AG,Fisher JP

更新日期：2017-04-12 00:00:00

abstract：:Tissue engineering based on building blocks is an emerging method to fabricate 3D tissue constructs. This method requires depositing and assembling building blocks (cell-laden microgels) at high throughput. The current technologies (e.g., molding and photolithography) to fabricate microgels have throughput challenges ...

journal_title：Biofabrication

authors： Xu F,Moon SJ,Emre AE,Turali ES,Song YS,Hacking SA,Nagatomi J,Demirci U

更新日期：2010-03-01 00:00:00

abstract：:We have developed cell sheet technology as a modern method for the fabrication of functional tissue-like and organ-like structures. This technology allows for a sheet of interconnected cells and cells in full contact with their natural extracellular environment to be obtained. A cell sheet can be patterned and compose...

journal_title：Biofabrication

authors： Hannachi IE,Yamato M,Okano T

更新日期：2009-06-01 00:00:00

abstract：:Nature has evolved to grow and regenerate tissues and organs using self-assembling processes capable of organizing a wide variety of molecular building-blocks at multiple size scales. As the field of biofabrication progresses, it is essential to develop innovative ways that can enhance our capacity to build more compl...

journal_title：Biofabrication

authors： Hedegaard CL,Mata A

更新日期：2020-06-01 00:00:00

abstract：:Three-dimensional (3D) tissue models are invaluable tools that can closely reflect the in vivo physiological environment. However, they are usually difficult to develop, have a low throughput and are often costly; limiting their utility to most laboratories. The recent availability of inexpensive additive manufacturin...

journal_title：Biofabrication

authors： Flood P,Alvarez L,Reynaud EG

更新日期：2016-10-11 00:00:00

abstract：:A major limitation of existing 3D implantable structures for bone tissue engineering is that most of the cells rapidly attach on the outer edges of the structure, restricting the cells penetration into the inner parts and causing the formation of a necrotic core. Furthermore, these structures generally possess a rando...

journal_title：Biofabrication

authors： Paun IA,Popescu RC,Mustaciosu CC,Zamfirescu M,Calin BS,Mihailescu M,Dinescu M,Popescu A,Chioibasu D,Soproniy M,Luculescu CR

更新日期：2018-02-05 00:00:00

abstract：:Omentum-based matrices fabricated by decellularization have the potential to serve as autologous scaffolds for tissue engineering. Transplantation of such scaffolds prepared from the patient's own biomaterial may reduce the immunogenic response after transplantation. Recently we reported on the potential of the decell...

journal_title：Biofabrication

authors： Soffer-Tsur N,Shevach M,Shapira A,Peer D,Dvir T

更新日期：2014-09-01 00:00:00

abstract：:The tumour microenvironment is heterogeneous and consists of multiple cell types, variable extracellular matrix (ECM) composition, and contains cell-defined gradients of small molecules, oxygen, nutrients and waste. Emerging in vitro cell culture systems that attempt to replicate these features often fail to incorpora...

journal_title：Biofabrication

authors： Rodenhizer D,Cojocari D,Wouters BG,McGuigan AP

更新日期：2016-10-18 00:00:00

abstract：:Bioprinting of living cells is rapidly developing as an advanced biofabrication approach to engineer tissues. Bioinks can be extruded in three-dimensions (3D) to fabricate complex and hierarchical constructs for implantation. However, a lack of functionality can often be attributed to poor bioink properties. Indeed, a...

journal_title：Biofabrication

authors： Cidonio G,Alcala-Orozco CR,Lim KS,Glinka M,Mutreja I,Kim YH,Dawson JI,Woodfield TBF,Oreffo ROC

更新日期：2019-06-12 00:00:00

abstract：:Engineering surfaces with functional polymers is a crucial issue in the field of micro/nanofabrication and cell-material interface studies. For many applications of surface patterning, it does not need cells to attach on the whole surface. Herein, we introduce a novel polymer fabrication protocol of off-stoichiometry ...

journal_title：Biofabrication

authors： Liu W,Li Y,Ding X

更新日期：2017-04-24 00:00:00

abstract：:Cell-imprinting technology is a novel method for directing stem cell fate using substrates molded from target cells. Here, we fabricated and studied cell-imprinted substrates for neural priming in human adipose-derived stem cells in the absence of chemical cues. We molded polydimethylsiloxane (PDMS) silicone substrate...

journal_title：Biofabrication

authors： Ghazali ZS,Eskandari M,Bonakdar S,Renaud P,Mashinchian O,Shalileh S,Bonini F,Uckay I,Preynat-Seauve O,Braschler T

更新日期：2020-10-30 00:00:00

abstract：:In this study, we report the step-gradient nanocomposite (NC) hydrogel generated easily by spatial connection of different nanocomposite hydrogel pastes varying in the concentrations of nanomaterials with the aid of a 3D printing technique. The prepared 3D printed gradient NC hydrogel has self-adhesive properties and ...

journal_title：Biofabrication

authors： Motealleh A,Çelebi-Saltik B,Ermis N,Nowak S,Khademhosseini A,Kehr NS

更新日期：2019-08-22 00:00:00

abstract：:We report a method for preparing cell-laden hydrogel tubes. This method uses a coaxial double-orifice spinneret, simpler than triple-orifice spinnerets which have been used for preparing similar constructs. The intended application was to create a template for preparing filament-like structures composed of two heterog...

journal_title：Biofabrication

authors： Sakai S,Liu Y,Mah EJ,Taya M

更新日期：2013-03-01 00:00:00

abstract：:Calcium alginate hydrogels are widely used as biocompatible materials in a substantial number of biomedical applications. This paper reports on a hybrid 3D printing and electrodeposition approach for forming 3D calcium alginate hydrogels in a controllable manner. Firstly, a specific 3D hydrogel printing system is deve...

journal_title：Biofabrication

authors： Shang W,Liu Y,Wan W,Hu C,Liu Z,Wong CT,Fukuda T,Shen Y

更新日期：2017-06-07 00:00:00

abstract：:A major challenge in muscle tissue engineering is mimicking the ordered nanostructure of native collagen fibrils in muscles. Electrospun nanofiber constructs have been proposed as promising candidate alternatives to natural extracellular matrix. Here, we introduce a novel method to fabricate a two-dimension (2D) sheet...

journal_title：Biofabrication

authors： Park SH,Koh UH,Kim M,Yang DY,Suh KY,Shin JH

更新日期：2014-06-01 00:00:00

abstract：:The high attrition rate of neuro-pharmaceuticals as they proceed to market necessitates the development of clinically-relevant in vitro neural microphysiological systems that can be utilized during the preclinical screening phase to assess the safety and efficacy of potential compounds. Historically, proposed models h...

journal_title：Biofabrication

authors： Bowser DA,Moore MJ

更新日期：2019-10-21 00:00:00

abstract：:Critical understanding of the complex metastatic cascade of prostate cancer is necessary for the development of a therapeutic interventions for treating metastatic prostate cancer. Increasing evidence supports the synergistic role of biochemical and biophysical cues in cancer progression at metastases. The biochemical...

journal_title：Biofabrication

authors： Jasuja H,Kar S,Katti DR,Katti K

更新日期：2021-01-08 00:00:00

abstract：:Plant cell cultures produce active agents for pharmaceuticals, food and cosmetics. However, up to now process control for plant cell suspension cultures is challenging. A positive impact of cell immobilization, such as encapsulation in hydrogel beads, on secondary metabolites production has been reported for several p...

journal_title：Biofabrication

authors： Seidel J,Ahlfeld T,Adolph M,Kümmritz S,Steingroewer J,Krujatz F,Bley T,Gelinsky M,Lode A

更新日期：2017-11-14 00:00:00

abstract：:Fabricating three-dimensional, biocompatible microenvironments to support functional tissue assembly remains a key challenge in cardiac tissue engineering. We hypothesized that since the omentum can be removed from patients by minimally invasive procedures, the obtained underlying matrices can be manipulated to serve ...

journal_title：Biofabrication

authors： Shevach M,Soffer-Tsur N,Fleischer S,Shapira A,Dvir T

更新日期：2014-06-01 00:00:00

abstract：:Cell therapy represents a promising option for revascularization of ischemic tissues. However, injection of dispersed cells is not optimal to ensure precise homing into the recipient's vasculature. Implantation of cell-engineered scaffolds around the occluded artery may obviate these limitations. Here, we employed the...

journal_title：Biofabrication

authors： Carrabba M,De Maria C,Oikawa A,Reni C,Rodriguez-Arabaolaza I,Spencer H,Slater S,Avolio E,Dang Z,Spinetti G,Madeddu P,Vozzi G

更新日期：2016-03-24 00:00:00

abstract：:Electrospinning has been widely used to produce ultrafine fibers in microscale and nanoscale; however, traditional electrospinning processes are currently beset by troublesome limitations in fabrication of 3D periodic porous structures because of the chaotic nature of the electrospinning jet. Here we report a novel st...

journal_title：Biofabrication

authors： Yuan H,Zhou Q,Li B,Bao M,Lou X,Zhang Y

更新日期：2015-11-05 00:00:00

abstract：:An important unsolved challenge in tissue engineering has been the inability to replicate the geometry and function of vascular networks and blood vessels. Here, we engineer a user-defined 3D microfluidic vascular channel using 3D printing-enabled hydrogel casting. First, a hollow L-shaped channel is developed using a...

journal_title：Biofabrication

authors： Yang L,Shridhar SV,Gerwitz M,Soman P

更新日期：2016-08-26 00:00:00

abstract：:Tissue engineering needs innovative solutions to better fit the requirements of a minimally invasive approach, providing at the same time instructive cues to cells. The use of shape memory polyurethane has been investigated by producing 4D scaffolds via additive manufacturing technology. Scaffolds with two different p...

journal_title：Biofabrication

authors： Hendrikson WJ,Rouwkema J,Clementi F,van Blitterswijk CA,Farè S,Moroni L

更新日期：2017-08-02 00:00:00

abstract：:Technical limitations of traditional electrospinning make it hard to produce three-dimensional (3D) scaffolds with hierarchical pore structures. Here, porous polycaprolactone (PCL) nanofiber meshes with different nano-hydroxyapatite (nHA) concentrations were prepared by electrospinning with stainless steel mesh as the...

journal_title：Biofabrication

authors： Song J,Zhu G,Wang L,An G,Shi X,Wang Y

更新日期：2017-02-14 00:00:00

abstract：:The inkjet ejection technology used in printers has been adopted and research has been conducted on manufacturing artificial tissue by patterning cells through micronozzle ejection of small droplets containing multiple cells. However, stable injection of cells has proven difficult, owing to the frequent occurrence of ...

journal_title：Biofabrication

authors： Yamaguchi S,Ueno A,Akiyama Y,Morishima K

更新日期：2012-12-01 00:00:00

abstract：:Drop-on-demand (DoD) inkjet printing has been explored for a range of applications, including those to selectively deposit cellular material, due to the high accuracy and scalability of such systems when compared with alternative bioprinting techniques. Despite this, there remain considerable limitations when handling...

journal_title：Biofabrication

authors： Dudman JPR,Ferreira AM,Gentile P,Wang X,Ribeiro RDC,Benning M,Dalgarno KW

更新日期：2020-08-12 00:00:00

abstract：:Bone healing is regulated by multiple microenvironmental signals provided by the extracellular matrix (ECM). This study aimed to mimic the native osteoinductive microenvironment by developing an ECM using gene-transduced cells. The LIM mineralization protein-1 (LMP-1) gene was transferred to murine pre-osteoblast cell...

journal_title：Biofabrication

authors： Ma J,Guo W,Gao M,Huang B,Qi Q,Ling Z,Chen Y,Hu H,Zhou H,Yu F,Chen K,Richards G,Lin J,Zhou Z,Xiao D,Zou X

更新日期：2017-11-14 00:00:00