Abstract:
Purpose:To investigate choroidal hyper-reflective foci (HRF) in subjects with retinal dystrophy [Stargardt's disease (SGD) and retinitis pigmentosa (RP)] and their association with demographics, visual acuity, choroidal thickness (CT), and choroidal vascularity index (CVI). Methods:Single center retrospective study of subjects with previously diagnosed SGD or RP. Swept-source optical coherence tomography images were analyzed for the presence of choroidal HRFs and CVI using previously validated automated algorithm. A Spearman's rank correlation coefficient was used to evaluate the correlation between the number of HRF and various baseline parameters including age, visual acuity, intraocular pressure, and other optical coherence tomography (OCT) parameters (CT, choroidal area, and CVI) were evaluated in these subjects. Results:This study included 46 eyes (23 subjects) and 55 eyes (28 subjects) with previously diagnosed RP and SGD, respectively. In the RP group, the mean number of HRFs was 247.9 ± 57.1 and mean CVI was 0.56 ± 0.04. In SGD group, mean HRF was 192.5 ± 44.3 and mean CVI was 0.41 ± 0.04. Mean HRF was significantly greater in the RP group (0.02), however, the mean CVI was not statistically different. In RP, mean HRF were correlated only with CVI (r = 0.49; P = 0.001), however, in SGD, it correlated with only choroidal area (r = 0.27; P = 0.04). Conclusion:Choroidal HRF were present in both RP and SGD subjects with more HRFs in those with RP. These HRFs were associated with alteration in choroidal vascularity, which further adds into the pathogenesis of these diseases.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Hanumunthadu D,Rasheed MA,Goud A,Gupta A,Vupparaboina KK,Chhablani Jdoi
10.4103/ijo.IJO_148_19subject
Has Abstractpub_date
2020-01-01 00:00:00pages
130-133issue
1eissn
0301-4738issn
1998-3689pii
IndianJOphthalmol_2020_68_1_130_273198journal_volume
68pub_type
杂志文章abstract:Purpose:To evaluate the long-term outcomes of cataract surgery in children with uveitis. Methods:Retrospective, noncomparative review of medical records of children (≤16 years) with uveitic cataract who had undergone cataract surgery between January 2001 and December 2014 at a tertiary care center was done. The main o...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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abstract::Parasites are a group of eukaryotic organisms that may be free-living or form a symbiotic or parasitic relationship with the hosts. Consisting of over 800,000 recognized species, parasites may be unicellular (Protozoa) or multicellular (helminths and arthropods). The association of parasites with human population star...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.278367
更新日期:2020-03-01 00:00:00
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journal_title:Indian journal of ophthalmology
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doi:
更新日期:1993-12-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
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更新日期:2018-12-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_1560_20
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doi:10.4103/0301-4738.39124
更新日期:2008-03-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,多中心研究
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1990-07-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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更新日期:2012-05-01 00:00:00
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
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更新日期:2020-12-01 00:00:00
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journal_title:Indian journal of ophthalmology
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1999-03-01 00:00:00
abstract:: ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
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