Genetically Encoded Inverse Bolaamphiphiles.

abstract：:Amphiphilic polymer conetworks (APCNs) are materials with a very large interface between their hydrophilic and hydrophobic phases due to their nanophase-separated morphologies. Proteins were found to enrich in APCNs by up to 2 orders of magnitude when incubated in aqueous protein solutions, raising the question of the...

journal_title：Biomacromolecules

authors： Dech S,Cramer T,Ladisch R,Bruns N,Tiller JC

更新日期：2011-05-09 00:00:00

abstract：:The design of functional systems with sizes in the nanometer range is a key challenge in fields such as biomedicine, nanotechnology, and engineering. Some of the most promising materials nowadays consist of self-assembling peptides or peptide-polymer hybrid materials because of their versatility and the resulting prop...

journal_title：Biomacromolecules

authors： Mikhalevich V,Craciun I,Kyropoulou M,Palivan CG,Meier W

更新日期：2017-11-13 00:00:00

abstract：:This study clarifies the contribution to overall osmotic kinetics of colloid osmotic pressure (Pi) and the interaction of synthetic colloids with the membrane. Solutions (6%) of dextran with weight average molecular weight (MW(w)) 68 800 (DEX 70), dextran with MW(w) 40 000 (DEX 40), hydroxyethyl starch with MW(w) 70 0...

journal_title：Biomacromolecules

authors： Tatara T,Tashiro C

更新日期：2005-05-01 00:00:00

abstract：:We report structural and dynamical aspects of DNAs from various sources including synthetic oligonucleotides in bulk buffer and as a complex with histone1 (H1). High-resolution transmission electron microscopic (HRTEM) studies reveal the structural change of the DNAs upon complexation with H1 leading to formation of c...

journal_title：Biomacromolecules

authors： Sarkar R,Pal SK

更新日期：2007-11-01 00:00:00

abstract：:The synthesis, characterization, and degradation kinetics of three alpha-cyclodextrin (alpha-CD)-poly(ethylene glycol) (PEG) polyrotaxanes with endcaps that were installed using Cu(I)-catalyzed Huisgen cyclization is reported. PEG1500, azidated with azidoacetic acid, was threaded with alpha-CD to form a pseudopolyrota...

journal_title：Biomacromolecules

authors： Loethen S,Ooya T,Choi HS,Yui N,Thompson DH

更新日期：2006-09-01 00:00:00

abstract：:The affinity of surfaces toward proteins is found to be a key parameter to govern the synthesis of polymer brushes by surface-initiated biocatalytic atom transfer radical polymerization (SI-bioATRP). While the "ATRPase" hemoglobin (Hb) stimulates only a relatively slow growth of protein repellent brushes, the synthesi...

journal_title：Biomacromolecules

authors： Divandari M,Pollard J,Dehghani E,Bruns N,Benetti EM

更新日期：2017-12-11 00:00:00

abstract：:Since their discovery at the end of the previous millennium, carbon nanotubes (CNTs) have been the object of thousands of papers describing their applications in fields ranging from physics to electronics, photonics, chemistry, biology, and medicine. The development of chemical approaches to modify their graphitic sid...

journal_title：Biomacromolecules

authors： Bottini M,Rosato N,Bottini N

更新日期：2011-10-10 00:00:00

abstract：:This paper describes the synthesis and evaluation of a series of multifunctional poly-l-glutamic acid derivatives that can be used as vectors for gene delivery. They readily form polyelectrolyte complexes with DNA, resulting in a reduced surface charge and size of the DNA. The formation of a polymer-DNA complex and th...

journal_title：Biomacromolecules

authors： Dubruel P,Dekie L,Schacht E

更新日期：2003-09-01 00:00:00

abstract：:Biobased poly(γ-butyrolactone) (PγBL) as a fully biodegradable and bioabsorbable biomaterial has shown superior properties compared to those of other aliphatic polyesters. It is of great importance to prepare amphiphilic block copolymer containing PγBL block to make ordered nano-objects for biomedical applications suc...

journal_title：Biomacromolecules

authors： Shen Y,Zhang J,Zhao Z,Zhao N,Liu F,Li Z

更新日期：2019-01-14 00:00:00

abstract：:Glycerol derivatives of cutin and suberin monomers were synthesized by acid catalysis. Their dispersion in an aqueous solution was examined by phase contrast microscopy, neutron scattering, and solid state NMR. It is shown that the phase behavior strongly depends on the nature of the derivatives forming either lumps o...

journal_title：Biomacromolecules

authors： Douliez JP,Barrault J,Jerome F,Heredia A,Navailles L,Nallet F

更新日期：2005-01-01 00:00:00

abstract：:Nanoparticles (NPs) composed of chitosan (CS) and poly(gamma-glutamic acid) (gamma-PGA) were prepared by a simple ionic-gelation method for oral insulin delivery. Fourier transform infrared (FT-IR) spectra indicated that CS and gamma-PGA were ionized at pH 2.5-6.6, while X-ray diffractograms demonstrated that the crys...

journal_title：Biomacromolecules

authors： Lin YH,Mi FL,Chen CT,Chang WC,Peng SF,Liang HF,Sung HW

更新日期：2007-01-01 00:00:00

abstract：:We have studied the degradation of well-characterized soluble heteropolymeric chitosans by a novel family 46 chitosanase, ScCsn46A from Streptomyces coelicolor A3(2), to obtain insight into the enzyme's mode of action and to determine its potential for production of different chitooligosaccharides. The degradation of ...

journal_title：Biomacromolecules

authors： Heggset EB,Dybvik AI,Hoell IA,Norberg AL,Sørlie M,Eijsink VG,Vårum KM

更新日期：2010-09-13 00:00:00

abstract：:The supramolecular organization of self-assembled stoichiometric complexes formed by dodecyltrimethylammonium cations and ionized poly(gamma-glutamic) acid has been investigated in chloroform solution. Atomistic molecular dynamics simulations have been performed considering three different starting conformations for t...

journal_title：Biomacromolecules

authors： Zanuy D,Alemán C

更新日期：2007-02-01 00:00:00

abstract：:Although the field of cancer immunotherapy is intensively investigated, there is still a need for generic strategies that allow easy, mild and efficient formulation of vaccine antigens. Here we report on a generic polymer-protein ligation strategy to formulate protein antigens into reversible polymeric conjugates for ...

journal_title：Biomacromolecules

authors： Lybaert L,Vanparijs N,Fierens K,Schuijs M,Nuhn L,Lambrecht BN,De Geest BG

更新日期：2016-03-14 00:00:00

abstract：:A strategy to manipulate the disulfide bond breaking triggered unfolding, and subsequently assembly of human serum albumin (HSA) in a lipophilic drug-dependent manner is present. In this study, the hydrophobic region, a molecular switch of the HSA, was regulated to form HSA-paclitaxel (HSA-PTX) nanoparticles by a faci...

journal_title：Biomacromolecules

authors： Gong G,Xu Y,Zhou Y,Meng Z,Ren G,Zhao Y,Zhang X,Wu J,Hu Y

更新日期：2012-01-09 00:00:00

abstract：:The synthesis and polymerization of six AB(3) tapered self-assembling methacrylate monomers (5a, 5b, 5c,5d, 17a, and 17b) based on first generation alkyl substituted benzyl ether monodendrons (i.e., minidendrons) containing oligooxyethylene units at their focal point and the polymerizable group on their periphery are ...

journal_title：Biomacromolecules

authors： Percec V,Bera TK

更新日期：2002-01-01 00:00:00

abstract：:This paper reports the synthesis of hyaluronan (HA) and its derivatives via the hyaluronidase-catalyzed polymerization of 2-substituted oxazoline derivative monomers designed as "transition-state analogue substrates". Polymerization of 2-methyl oxazoline monomer from N-acetylhyalobiuronate (GlcAbeta(1-->3)GlcNAc) effe...

journal_title：Biomacromolecules

authors： Ochiai H,Ohmae M,Mori T,Kobayashi S

更新日期：2005-03-01 00:00:00

abstract：:In the present study, novel bionanocomposite materials with tunable properties were successfully prepared using a poly(lactic acid) (PLA) matrix and acetylated microfibrillated cellulose (MFC) as reinforcing agent. The acetylation of MFC was confirmed by FTIR and (13)C CP-MAS NMR spectroscopies. The grafting of acetyl...

journal_title：Biomacromolecules

authors： Tingaut P,Zimmermann T,Lopez-Suevos F

更新日期：2010-02-08 00:00:00

abstract：:Poly(3-hydroxybutyrate) (PHB) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) are biopolyesters reported to provide favorable microenvironments for cell culture and possess potential for tissue engineering applications. Both biopolymers have been investigated for applications in a variety of medical scenarios,...

journal_title：Biomacromolecules

authors： Ahmed T,Marçal H,Lawless M,Wanandy NS,Chiu A,Foster LJ

更新日期：2010-10-11 00:00:00

abstract：:Cellulose nanocrystals (CNCs) are mechanically rigid, toxicologically benign, fiber-like nanoparticles. They can easily be extracted from renewable biosources and have attracted significant interest as reinforcing fillers in polymers. We here report the modification of CNCs with the 2-ureido-4[1H]pyrimidinone (UPy) mo...

journal_title：Biomacromolecules

authors： Natterodt JC,Sapkota J,Foster EJ,Weder C

更新日期：2017-02-13 00:00:00

abstract：:Reduction-sensitive shell-sheddable glyco-nanoparticles were designed and developed based on poly(ε-caprolactone)-graft-SS-lactobionic acid (PCL-g-SS-LBA) copolymer for efficient hepatoma-targeting delivery of doxorubicin (DOX). PCL-g-SS-LBA was prepared by ring-opening copolymerization of ε-caprolactone and pyridyl d...

journal_title：Biomacromolecules

authors： Chen W,Zou Y,Meng F,Cheng R,Deng C,Feijen J,Zhong Z

更新日期：2014-03-10 00:00:00

abstract：:N-(3-Aminopropyl)pyrrole was covalently coupled with alginate in an aqueous-phase reaction by means of carbodiimide-mediated activation chemistry to provide a pyrrole-alginate conjugate for subsequent use in biosensor applications. The pyrrole-alginate conjugate was quantified by UV spectroscopy at 230 nm, by an HPSEC...

journal_title：Biomacromolecules

authors： Abu-Rabeah K,Polyak B,Ionescu RE,Cosnier S,Marks RS

更新日期：2005-11-01 00:00:00

abstract：:Water-soluble T-antigen containing glycopolymers [Gal beta(1,3)-GalNAc alpha) having a high degree of lipophilicity were synthesized from poly[N-(acryloxy)succinimide] (6-10) by amidation with an amine-ending T-antigen derivative (3) and various amines of increasing alkyl chain length (ammonia and methyl-, ethyl-, and...

journal_title：Biomacromolecules

authors： Baek MG,Roy R

更新日期：2000-01-01 00:00:00

abstract：:We have investigated the self-assembly of fluorenylmethoxycarbonyl-conjugated dialanine (Fmoc-AA) molecules using combined computational and experimental approaches. Fmoc-AA gels were characterized using transmission electron microscopy (TEM), circular dichroism (CD), Fourier transform infrared (FTIR), and wide-angle ...

journal_title：Biomacromolecules

authors： Mu X,Eckes KM,Nguyen MM,Suggs LJ,Ren P

更新日期：2012-11-12 00:00:00

abstract：:This paper reports the rheological behavior of chitosan solutions that have been cross-linked with different amounts of genipin, at body temperature and physiological pH. The effect of the cross-linker loading on the rheological properties of hydrogels has been evaluated. The oscillatory time sweep method was used to ...

journal_title：Biomacromolecules

authors： Moura MJ,Figueiredo MM,Gil MH

更新日期：2007-12-01 00:00:00

abstract：:We have developed herein an engineered polymer-based nanoplatform showing the convergence of two-photon fluorescence imaging and bimodal phototherapeutic activity in a single nanostructure. It was achieved through the appropriate choice of three different components: a β-cyclodextrin-based polymer acting as a suitable...

journal_title：Biomacromolecules

authors： Kandoth N,Kirejev V,Monti S,Gref R,Ericson MB,Sortino S

更新日期：2014-05-12 00:00:00

abstract：:The unsatisfied results of cancer therapy are caused by many issues and metastasis of cancer cells is one of the major challenge. It has been reported that inhibiting the SDF1/CXCR4 interaction can significantly reduce the metastasis of breast cancer cells to regional lymph nodes and lung. Herein, a nanogel system equ...

journal_title：Biomacromolecules

authors： Zhang F,Gong S,Wu J,Li H,Oupicky D,Sun M

更新日期：2017-06-12 00:00:00

abstract：:The effect of increasing water composition on the rheological and microstructural behavior of a ternary cellulose acetate (CA)/N,N-dimethylacetamide (DMA)/water system is examined. Addition of water to the CA/DMA system results in enhanced steady shear viscosity and dynamic viscoelastic properties and ultimately to ph...

journal_title：Biomacromolecules

authors： Appaw C,Gilbert RD,Khan SA,Kadla JF

更新日期：2007-05-01 00:00:00

abstract：:The development and use of synthetic, cross-linked, macromolecular substrates with tunable elasticity has been instrumental in revealing the mechanisms by which cells sense and respond to their mechanical microenvironment. We here describe a hydrogel based on radical-free, cross-linked poly(ethylene glycol) to study t...

journal_title：Biomacromolecules

authors： Missirlis D,Spatz JP

更新日期：2014-01-13 00:00:00

abstract：:In the present contribution, two-dimensional ATR-FTIR spectroscopy was used to study the diffusion of water in poly(epsilon-caprolactone) (PCL). In the spectral region of the nu(OH) stretching vibration of water, four absorption bands (3635, 3560, 3411, and 3220 cm(-1)) can be identified. The higher wavenumber band pa...

journal_title：Biomacromolecules

authors： Peng Y,Wu P,Siesler HW

更新日期：2003-07-01 00:00:00