Corneal alteration and pathogenesis in diabetes mellitus.

abstract：AIM:To evaluate the functional and aesthetic outcomes of upper eyelid cicatricial entropion (UCE) correction using anterior lamellar recession (ALR) with addressing the associated conditions including dermatochalasis, brow ptosis, blepharoptosis, and lid retraction. METHODS:Chart review of patients with upper lid cica...

journal_title：International journal of ophthalmology

authors： Gawdat TI,Kamal MA,Saif AS,Diab MM

更新日期：2017-12-18 00:00:00

abstract：AIM:To study the effect of Rac1 on the induction of HIF-1α in choroidal neovascularization (CNV) in mice. METHODS:One hundred C57BL/6J mice were laser photocoagulated to induce CNV, fifty mice of that were selected randomly for intravitreal injection of Rac1 inhibitor NSC23766 solution (1µL). After laser photocoagulat...

journal_title：International journal of ophthalmology

authors： Zhang P,Zhang X,Fan JL,Hao XF,Wang YS,Hui YN,Hu D,Zhou J

更新日期：2011-01-01 00:00:00

abstract：:Valsalva retinopathy was described as a particular form of retinopathy, pre-retinal and subinternal limiting membrane haemorrhages in nature that rarely may break through and become subhyloid or intravitreal, secondary to a sudden increase in intrathoracic pressure. We reported a new way that Nd:YAG laser for ILM hyal...

journal_title：International journal of ophthalmology

authors： Hua R,Liu LM,Hu YD,Zhou Y,Chen L

更新日期：2013-04-18 00:00:00

abstract：AIM:To investigate the efficacy and safety of the treatment of endoscopic trans-ethmosphenoid optic canal decompression (ETOCD) with combination of steroid in patients with newly onset indirect traumatic optic neuropathy (ITON) and compare the outcome between immediate ETOCD treatment and ETOCD with preoperative steroi...

journal_title：International journal of ophthalmology

authors： Yu B,Ma YJ,Tu YH,Wu WC

更新日期：2020-01-18 00:00:00

abstract：AIM:To evaluate the effect of sodium tungstate on visual evoked potentials (VEPs) in diabetic rats. METHODS:Wistar rats were randomly divided into three groups as normal control, diabetic control and diabetic rats treated with sodium tungstate. Diabetes was induced by single intraperitoneal injection of streptozotocin...

journal_title：International journal of ophthalmology

authors： Bulut M,Dönmez BÖ,Öztürk N,Başaranlar G,Kencebay Manas C,Derin N,Özdemir S

更新日期：2016-05-18 00:00:00

abstract：AIM:To evaluate the efficacy of modified corneal ulcer debridement in superficial fungal keratitis unresponsive to medications. METHODS:A total of 209 patients (209 eyes) with fungal keratitis, involving no more than 50% of the stromal depth and not responding to antifungal agents for 2wk, were recruited in this retro...

journal_title：International journal of ophthalmology

authors： Wang JY,Wang DQ,Qi XL,Cheng J,Xie LX

更新日期：2018-02-18 00:00:00

abstract：AIM:To evaluate the neuroprotective effect of rosuvastatin, in a rat experimental glaucoma model. METHODS:Ocular hypertension was induced in right eyes of Long-Evans rats (n=30) by cauterization of three episcleral veins. Left eyes were defined as controls. Rats were divided into five groups: oral rosuvastatin, intrav...

journal_title：International journal of ophthalmology

authors： Unlu M,Aktas Z,Gocun PU,Ilhan SO,Hasanreisoglu M,Hasanreisoglu B

更新日期：2016-03-18 00:00:00

abstract：AIM:To analyze the efficacy of ultraviolet (UV) light initiating corneal cross-linking (CXL). METHODS:The time-dependent absorption of UV light due to the depletion of the initiator (riboflavin) was calculated. The effective dose of CXL with corneal surface covered by a thin layer of riboflavin was derived analyticall...

journal_title：International journal of ophthalmology

authors： Zhang Y,Wang KC,Chang CK,Lin JT

更新日期：2016-08-18 00:00:00

abstract：AIM:To investigate microvascular changes in eyes with central retinal vein occlusion (CRVO) complicated by macular edema before and after intravitreal conbercept injection and evaluate correlations between these changes and best-corrected visual acuity (BCVA) and retinal thickness. METHODS:Twenty-eight eyes of 28 pati...

journal_title：International journal of ophthalmology

authors： Deng Y,Zhong QW,Zhang AQ,Cai XJ,Lu MZ,Zhang SC,Su LS,Chen H,Lin Y,Sun LM,Chen GD,Zhong LT,Jin CJ,Chi W

更新日期：2019-05-18 00:00:00

abstract：AIM:To assess if the included vascular endothelial growth factor (VEGF) polymorphisms rs3025035, rs3025021 and rs2010963 are associated to proliferative retinopathy in a Mexican population with type 2 diabetes mellitus (T2DM). METHODS:A case-control study was conducted in adult individuals with T2DM associated to prol...

journal_title：International journal of ophthalmology

authors： Gonzalez-Salinas R,Garcia-Gutierrez MC,Garcia-Aguirre G,Morales-Canton V,Velez-Montoya R,Soberon-Ventura VR,Gonzalez V,Lechuga R,Garcia-Solis P,Garcia-Gutierrez DG,Garcia-Solis MV,Saenz de Viteri M,Solis-S JC

更新日期：2017-01-18 00:00:00

abstract：AIM:To attempt to identify the primary targets of carbamylation in bovine lenses incubated under physiological condition. METHODS:Fresh intact bovine lenses were incubated with [(14)C]-labelled potassium cyanate for seven days. The water-soluble proteins (WSP) of both cortex and nucleus lens were isolated by size-excl...

journal_title：International journal of ophthalmology

authors： Yan H,Zhang J,Harding JJ

更新日期：2010-01-01 00:00:00

abstract：:The use of personal protective equipment (PPE) for ophthalmologists caring for asymptomatic patients remains controversial. This commentary reviews the latest emerging evidence. This is paramountly important in shaping health policies in countries which is not currently recommended. ...

journal_title：International journal of ophthalmology

authors： Fung AT

更新日期：2020-12-18 00:00:00

abstract：AIM:To compare the functional and anatomic results of femtosecond laser (FSL)-assisted deep anterior lamellar keratoplasty (DALK) associated with phototherapeutic keratectomy (PTK) and FSL-assisted DALK performed using the big-bubble technique in keratoconus. METHODS:During the first phase of the study, an electron mi...

journal_title：International journal of ophthalmology

authors： de Macedo JP,de Oliveira LA,Hirai F,de Sousa LB

更新日期：2018-05-18 00:00:00

abstract：AIM:To assess the refractive status, anterior chamber depth (ACD) and axial length (AL) of patients with primary angle-closure disease (PACD). METHODS:Retrospective cohort. Data was collected from charts of all PACD patients treated from April 2013 to December 2015. Analysis was done on 137 patient charts with complet...

journal_title：International journal of ophthalmology

authors： Mohamed-Noor J,Abd-Salam D

更新日期：2017-08-18 00:00:00

abstract：:As a non-penetrating glaucoma surgery (NPGS), canaloplasty aims to reconstruct the physiological outflow of aqueous humor by dilating the Schlemm's canal. Ab interno canaloplasty (ABiC), which can reconstruct the natural outflow pathways of aqueous humor in mild-to-moderate primary open angle glaucoma (POAG) patients,...

journal_title：International journal of ophthalmology

authors： Zhang J,Wang NL

更新日期：2019-10-18 00:00:00

abstract：AIM:To determine the epidemiological characteristics, clinical signs, laboratory findings, and outcomes in patients with corneal infection in Shandong peninsula of China. METHODS:The medical records of 578 inpatients (578 eyes) with corneal infection were reviewed retrospectively for demographic characteristics, risk ...

journal_title：International journal of ophthalmology

authors： Pan XJ,Jiang T,Zhu H,Liu PP,Zhou ZY,Mao AJ

更新日期：2016-01-18 00:00:00

abstract：AIM:To study the effects of curcumin on the secretion of interleukin (IL)-6 and IL-8 by corneal limbus epithelial cells. METHODS:Human corneal limbus epithelial cells were isolated and cultured from donor eyes and irradiated by UVB at different dosages with or without curcumin. MTT test was used for studying the effec...

journal_title：International journal of ophthalmology

authors： Chao SC,Hu DN,Roberts J,Shen X,Lee CY,Nien CW,Lin HY

更新日期：2017-06-18 00:00:00

abstract：AIM:To record aberrations with a corneal topographic device on the anterior surface of the cornea at different time-points prior to wearing and following discontinued use of rigid gas permeable (RGP) contact lenses. The effect of wearing RGP on the anterior surface of the cornea was discussed to provide guidance for cl...

journal_title：International journal of ophthalmology

authors： Yu Q,Wu JX,Zhang HN,Ye S,Dong SQ,Zhang CH

更新日期：2013-04-18 00:00:00

abstract：AIM:To observe the characteristics of iridociliary cysts in myopic patients and evaluate the influences on the position and safety of implantable collamer lens (ICL) after surgery. METHODS:Totally 270 eyes of 135 patients who underwent ICL surgery for the corrections of myopia were included in this study. Preoperative...

journal_title：International journal of ophthalmology

authors： Chen Q,Qi MY,Lei XH,Zeng QY

更新日期：2020-06-18 00:00:00

abstract：AIM:To investigate the effects of the phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 on retinal neovascularization (RNV) in the oxygen-induced retinopathy (OIR) mouse model and human umbilical vein endothelial cells (HUVECs). METHODS:C57BL/6J mice were randomly divided into normoxia-control, OIR-control and L...

journal_title：International journal of ophthalmology

authors： Di Y,Chen XL

更新日期：2018-08-18 00:00:00

abstract：AIM:To investigate the expression of the v-raf-1 murine leukemia viral oncogene homolog 1 (Raf-1) and its role in the innate immune response of human corneal epithelial cells (HCECs) infected by Aspergillus fumigatus. METHODS:HCECs were cultured in vitro. They were randomly divided into 4 groups, including control gro...

journal_title：International journal of ophthalmology

authors： Zhao GQ,Lin J,Hu LT,Yin XN,Wang Q,Xu Q,Li H

更新日期：2016-10-18 00:00:00

abstract：AIM:To evaluate ocular penetration of topically applied 1% tigecycline. METHODS:Forty-two New Zealand White rabbits were divided into 3 groups. A 50 µL drop of 1% tigecycline was administered in group 1. In groups 2 and 3, the drop was administered every 15min for 60min (keratitis protocol). Aqueous humor samples in g...

journal_title：International journal of ophthalmology

authors： Sakarya Y,Sakarya R,Ozcimen M,Goktas S,Ozcimen S,Alpfidan I,Ivacık IS,Erdogan E,Cetinkaya S,Bukus A

更新日期：2017-05-18 00:00:00

abstract：AIM:To investigate the impact of non-Descemet stripping endothelial keratoplasty (non-DSEK) on graft rejection rate, and its overall procedural effectiveness in patients. METHODS:Non-DSEK was performed on 65 eyes of 64 patients, and the procedural outcomes, including rejection episodes, failure and dislocation of the ...

journal_title：International journal of ophthalmology

authors： Zhang T,Li SW,Chen TH,He JL,Kang YW,Lyu FQ,Ning JH,Liu C

更新日期：2017-02-18 00:00:00

abstract：AIM:To investigate extent and nature of visual pathways involvement in children with clinically isolated syndrome (CIS). METHODS:Forty-seven patients (age 11-17y) with CIS, which later proved to be multiple sclerosis (MS) onset, and 30 controls underwent visual evoked potentials (VEP) investigation within 12d from the...

journal_title：International journal of ophthalmology

authors： Voitenkov V,Skripchenko N,Klimkin A

更新日期：2015-04-18 00:00:00

abstract：:This study is to investigate the characteristic features of Acanthamoeba keratitis (AK) that differentiating it from herpetic epithelial keratitis (HEK) using anterior segment optical coherence tomography (AS-OCT). Medical records of three eyes of each AK and herpetic keratitis who had AS-OCT examination were reviewed...

journal_title：International journal of ophthalmology

authors： Park YM,Lee JS,Yoo JM,Park JM,Seo SW,Chung IY,Kim SJ

更新日期：2018-08-18 00:00:00

abstract：:Non-simulator-based examination methods of the fundal examination have shown to be cost-effective. We reviewed different non-simulator-based direct fundoscopy examination methods used in undergraduate curricula and their outcomes. PubMed (MEDLINE) and Cochrane Database of Systematic Reviews were searched using standar...

journal_title：International journal of ophthalmology

authors： Samaranayake UMJE,Mathangasinghe Y,Samaranayake UMNP,Wijayatunga M

更新日期：2020-04-18 00:00:00

abstract：AIM:To evaluate postoperative visual acuity and contrast sensitivity results following deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) in patients with keratoconus (KC). METHODS:All the patients' records with KC who had PK or DALK surgery between May 2010 and May 2011 were retrospectively ...

journal_title：International journal of ophthalmology

authors： Akdemir MO,Kandemir B,Sayman IB,Selvi C,Kamil Dogan O

更新日期：2012-01-01 00:00:00

abstract：:With the evolution of cataract surgery from visual rehabilitation to refractive surgery, aspheric intraocular lenses (IOLs) are being increasingly used in the field of ophthalmology. This increased use can be attributed to negative or zero spherical aberrations with unique optical designs, which counteract some of the...

journal_title：International journal of ophthalmology

authors： Du W,Lou W,Wu Q

更新日期：2019-11-18 00:00:00

abstract：AIM:To investigate the epidemiology and surgical outcomes of old canalicular laceration and analyze the variables impacting on the prognosis of reparation. METHODS:A retrospective review of all old canalicular laceration repairs from Jan. 1, 2008 to Dec. 30, 2015 was performed. Analyzed data included demographics, mec...

journal_title：International journal of ophthalmology

authors： Bai F,Tao H,Zhang Y,Wang P,Han C,Huang YF,Tao Y

更新日期：2017-06-18 00:00:00

abstract：AIM:To evaluate the effect of age on visual and refractive results after laser in situ keratomileusis (LASIK) obtained with a mechanical microkeratome or a femtosecond laser. METHODS:Retrospective, nonrandomized, cohort study. A total of 3826 eyes were included in the study (1725 eyes treated with mechanical LASIK and...

journal_title：International journal of ophthalmology

authors： Garcia-Gonzalez M,Gros-Otero J,Rodriguez-Perez I,Rodero A,Teus MA

更新日期：2019-03-18 00:00:00