Retroactive interference of a learnt action-outcome association by exposure to a stimulus-outcome learning experience.

Abstract:

:The current study used the protocol established to produce retroactive interference (RI) in contextual memory paradigms and applied it to an appetitive learning setting. Rats were first subjected to the learning of an operant conditioning, action-outcome (A-O) association and were tested in a probe (A-O probe) session the following day. Rats that experienced an interpolated, classical conditioning, stimulus-outcome (S-O) learning experience performed more poorly in the probe session than those that did not undergo this experience. The S-O learning experience had therefore retroactively interfered with the A-O task. The degree of interference also varied with the amount of time lag between the three (A-O, S-O and the A-O probe) conditions. The current study is the first to show evidence of RI by an S-O learning experience on a recently learnt A-O association. These results are similar to those from hippocampal-dependent learning paradigms and indicate that interference of memory consolidation in an appetitive learning paradigm can be produced by an intervening task that is behaviourally distinct from the initial learning experience.

journal_name

Behav Processes

journal_title

Behavioural processes

authors

Pattabhiraman H,Ward RD

doi

10.1016/j.beproc.2019.104020

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

104020

eissn

0376-6357

issn

1872-8308

pii

S0376-6357(19)30331-6

journal_volume

170

pub_type

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