Preparation and application of alcohol based deep eutectic solvents for extraction of curcumin in food samples prior to its spectrophotometric determination.

Abstract:

:In this study, a novel, simple and economic vortex-assisted alcohol-based deep eutectic solvent microextraction (VA-DES-ME) procedure has been developed for the preconcentration of curcumin in food samples prior to its spectrophotometric determination. A alcohol-based-DES consists of betaine hydrochloride - glycerol (1:3) as extraction solvent and acetone as aprotic solvent at pH 6.0 were used for the preconcentration of curcumin from sample matrix. Some experimental variables such as pH, DES solvent type and volume, aprotic solvent type and volume, vortex time, sample volume and matrix effect etc. were investigated and optimized in detail. Under optimized conditions, the working range, limit of detection and pre-concentration factor were determined to be as 5-300 μg L-1 and 1.5 μg L-1 and 100 respectively. Validity of the proposed method was proved by the intra-day/inter-day precision studies and addition-recovery test. Consequently, the VA-DES-ME procedure was successfully applied for the extraction and determination of curcumin in food samples.

journal_name

Food Chem

journal_title

Food chemistry

authors

Altunay N,Elik A,Gürkan R

doi

10.1016/j.foodchem.2019.125933

subject

Has Abstract

pub_date

2020-04-25 00:00:00

pages

125933

eissn

0308-8146

issn

1873-7072

pii

S0308-8146(19)32072-2

journal_volume

310

pub_type

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