Abstract:
:Quantitative perfusion scans were used to predict the proportion of pulmonary function lost by inclusion of lung in radiotherapy fields. Nineteen patients receiving radiotherapy for carcinoma of the lung had pulmonary function evaluated by forced expiratory volume at 1 second (FEV1) prior to and following radiotherapy. FEV1 measurement followed initiation of radiotherapy from two to 18 months (mean: seven months). Prior to radiotherapy quantitative lung scans were performed with Tc-99m macroaggregated albumin. On images acquired by computer, the radiotherapy field was drawn as a region of interest (ROI) and the proportion of count within this ROI relative to total lung count was determined. The total FEV1 was apportioned by the ROI ratio of count excluded from radiation ROI to total count in lungs to predict the FEV1 expected to be remaining after radiotherapy. In only two cases was the measured post-therapy FEV1 less than predicted (and then, by only 2% and 5%, respectively). The data indicate that quantitative perfusion lung scans can be used to predict conservatively the pulmonary function that may be expected to remain post-radiotherapy. Therapy fields may be adjusted in patients with underlying compromised pulmonary function to conserve a pre-selected FEV1.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Moldofsky PJ,Rubenstein JH,Richter MP,Solin LJ,Gatenby RA,Broder GJdoi
10.1097/00003072-198809000-00006subject
Has Abstractpub_date
1988-09-01 00:00:00pages
644-6issue
9eissn
0363-9762issn
1536-0229journal_volume
13pub_type
杂志文章abstract::A 9-year-old girl had a 6-month history of left hip pain. Radiographs of the left hip showed a metaphyseal osteolytic lesion with sclerotic borders in the femoral neck. Tc-99m MDP bone imaging and a Ga-67 scan showed focal areas of increased activity in the left femoral neck. These areas of increased uptake correspond...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199510000-00013
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:Mammographic screening has led to the identification of more women with nonpalpable breast cancer, many of them to be treated with breast-preserving surgery. To accomplish radical tumor excision, adequate localization techniques such as radioactive seed localization (RSL) are required. For RSL, a radioactive...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001081
更新日期:2016-05-01 00:00:00
abstract::We presented a promising result of radionuclide therapy using Lu-PSMA and Lu-DOTATATE in a patient with prostatic adenocarcinoma and neuroendocrine differentiation. Functional imaging of somatostatin receptors in patients with metastatic castration-resistant prostate cancer may pave the way toward implementation of no...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002824
更新日期:2019-12-01 00:00:00
abstract::We report a rare case of a mediastinal malignant granular cell tumor in a 41-year-old man presenting with dyspnea, retrosternal chest pain, and recurrent pericardial effusion under treatment with corticosteroids. Because of recurrent episodes, further investigations with chest MRI and F-FDG PET/CT revealed a large inf...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002137
更新日期:2018-08-01 00:00:00
abstract::This is the first report in the nuclear medicine literature of the scintigraphic appearance of the piriformis muscle syndrome. This syndrome previously has been thought to be a purely clinical diagnosis and imaging modalities have been ignored. However, its confusing clinical presentation can lead to unnecessary surgi...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198505000-00011
更新日期:1985-05-01 00:00:00
abstract::This interesting image illustrates a case of biopsy-proven pulmonary anthracosilicosis, a mixed dust pneumoconiosis, associated with Ga-PSMA-ligand uptake. Prostate-specific membrane antigen (PSMA) is an emerging imaging biomarker, with clinical application in evaluation of prostate cancer using Ga-PSMA-ligand PET/CT....
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001782
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:Investigate the ability of F-fluorothymidine (FLT) PET combined with CT at 6 weeks to predict treatment response at 12 weeks after treatment with pembrolizumab. METHODS:Five patients with unresectable stage IV melanoma were included in this single-institution pilot study. Patients underwent FLT-PET/CT (baselin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002967
更新日期:2020-04-01 00:00:00
abstract::Patients with primary central nervous system lymphomas (PCNSLs) present with nonspecific clinical symptoms, which makes correct imaging evaluation essential for diagnostic and therapeutic management. In this work, we examined an 81-year-old man with recently discovered PCNSL using F-FDG PET/MRI, and we were able to di...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003067
更新日期:2020-07-01 00:00:00
abstract::PET/CT with Ga-labeled prostate-specific membrane antigen (PSMA) is increasingly recognized as the best imaging modality for disease staging and detection of recurrent prostate cancer. Despite its name, PSMA expression has been reported in a number of nonprostatic benign and malignant pathologies. Apparently, angioneo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002103
更新日期:2018-07-01 00:00:00
abstract::Primary seminoma of the prostate is extremely rare. We describe a case of a 35-year-old man who presented with difficulty in urinating. Physical findings were unremarkable, but a rectal examination revealed a slightly hardened prostate with a nodule in the right lobe. Blood parameters were normal; however, blood chemi...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182177350
更新日期:2011-07-01 00:00:00
abstract::We report a 58-year-old man whose incidentally discovered papillary thyroid carcinoma in the left lobe showed high FDG and low FLT uptake on PET/CT. The SUVmax was 19.7 for FDG and 3.0 for FLT. The Ki-67 labeling index of the tumor was 1.9%. Thus, the low FLT uptake might be attributed to the low proliferative activit...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318252d80f
更新日期:2012-06-01 00:00:00
abstract::Although the incidence of an organic cause is low and most of the detected genitourinary anomalies are not responsible for enuresis, a simple, noninvasive screening test is preferable in the analysis of children with enuresis. Extension of standard radionuclide renography as a method of screening the upper as well as ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199203000-00010
更新日期:1992-03-01 00:00:00
abstract::A 67-year-old woman was referred for staging of a mucosa-associated lymphoid tumor lymphoma involving the left conjunctiva. CT scan had shown paravertebral and pelvic masses, and a breast nodule. FDG PET/CT demonstrated moderately increased uptake in the left ocular conjunctiva and confirmed the paravertebral and pelv...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000356
更新日期:2014-03-01 00:00:00
abstract::Focal radionuclide accumulation of Tc-99m sulfur colloid (SC) and tc-99m macroaggregated albumin (MAA) in the liver has been reported in both inferior and superior vena caval obstruction. We studied a patient with uniform radionuclide accumulation of Tc-99m MAA in the liver during lung scintigraphy. In this patient, b...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198308000-00009
更新日期:1983-08-01 00:00:00
abstract::A 59-year-old man presented cough, chest pain, and shortness of breath for 2 weeks and fever for 4 days. A contrast chest CT revealed a large right pulmonary artery filling defect, suggestive of pulmonary embolism that failed to respond to anticoagulation therapy. FDG PET/CT was performed to evaluate possible malignan...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001248
更新日期:2016-08-01 00:00:00
abstract::Cortical alterations of brain metabolism, as seen in PET, obviously depend on the nature of the damage (either mechanical, toxic, anoxic, or other). However, some subcortical abnormalities seem to occur rather frequently regardless of the extension, position and cause of the damage. In particular, relative cerebellar ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3180537621
更新日期:2007-06-01 00:00:00
abstract::In three cases, irradiated regions of liver failed to concentrate Tc-99m-sulfur colloid. In two of these three, imaging with Tc-99m-acetanilide iminodiacetic acid (IDA) agents within five days showed near normal hepatic uptake of this hepatobiliary imaging agent. The hepatic parenchymal cells may be imaged with Tc-99m...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198109000-00003
更新日期:1981-09-01 00:00:00
abstract::We report a 65-year-old man with a right cerebral infarction that occurred 15 years ago and a residual left hemiparesis that began with progressive contralateral hemiparesis. During the hospitalization, the patient developed a bilateral alien hand syndrome. Urgent CT, MR, CT angiography, and brain perfusion SPECT were...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000637
更新日期:2015-03-01 00:00:00
abstract::We present an F-18 FDG PET scan which demonstrates 3 synchronous primary malignancies. The patient is a 61-year-old man who presented with weight loss and dysphagia. He was initially diagnosed with squamous cell carcinoma of the midesophagus, and was then found to have an adenocarcinoma in the right lung. A staging PE...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3180a1ad48
更新日期:2007-08-01 00:00:00
abstract::Two case reports of malignant pleural effusion from breast carcinoma, with scans showing a striking accumulation of Tc-99m MDP, are presented. The Tc-99m MDP was in the pleural fluid and not in the pleura as demonstrated by shift with gravity. Possible mechanisms of malignant effusion accumulation of Tc-99m MDP are su...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198207000-00009
更新日期:1982-07-01 00:00:00
abstract:ABSTRACT:A 13-year-old boy with mediastinal T-cell lymphoblastic lymphoma demonstrated an altered biodistribution with diffuse activity in subcutaneous white adipose tissue and decreased visceral activity on interim posttreatment FDG PET/CT. This altered biodistribution was attributed to administration of the chemother...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003340
更新日期:2021-03-01 00:00:00
abstract::A case of false-negative Tc-99m MDP bone scintigrams, taken at one and two weeks for pathologic fractures in a patient with metabolic bone disease and a super-scan appearance, is described. The patient had renal osteodystrophy, and postparathyroidectomy hypocalcemia. Postoperative seizures caused multiple pathologic f...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198707000-00004
更新日期:1987-07-01 00:00:00
abstract::Using serial perfusion lung scans, we have documented the opening up and closure of right-to-left intrapulmonary arteriovenous shunts over a period of several weeks in a patient with chronic alcoholic liver disease. The presence of the shunts correlates well with the severity of hypoxemia and the presence of nodular m...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198405000-00009
更新日期:1984-05-01 00:00:00
abstract:PURPOSE:Dynamic PET studies with a ⁶⁸Ga-Bombesin analog, the ⁶⁸Ga-BZH₃, were performed in patients with highly suspected recurrent gliomas to investigate the effect of the receptor scintigraphy on tumor grading. Furthermore, dynamic F-18 Fluorodeoxyglucose (FDG) studies were performed for comparison. METHODS:The study...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318203bb24
更新日期:2011-02-01 00:00:00
abstract::Increased bone activity in the sacroiliac joints has been shown to be a sensitive method for detecting sacroiliitis in brucellosis. Because symmetrically increased uptake usually is difficult to detect, this study was performed to improve the sensitivity by quantifying sacroiliac joint uptake. Quantification was accom...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199910000-00005
更新日期:1999-10-01 00:00:00
abstract::A 66-year-old man with castration-resistant prostate cancer was evaluated with F-prostate-specific membrane antigen (PSMA) 1007 PET/CT, which revealed extensive PSMA-positive skeletal metastases in the skull, thorax, spine, pelvis, and extremities. He was then treated Lu-PSMA-617 therapy. Twenty-four-hour SPECT/CT rev...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002982
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:The sensitivity of sestamibi scanning is 85% for breast lesions that measure >or=1 cm in diameter. This detection technique complements mammography and clinical examination and can benefit patients with very dense breast tissue. An innovation in nuclear imaging uses a lead marker for localization. MATERIALS AN...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200203000-00001
更新日期:2002-03-01 00:00:00
abstract::Retinal hemangioblastomas are highly vascular benign tumors that can be encountered either sporadically or within the von Hippel-Lindau (VHL) syndrome. We report a case of a VHL patient with retinal hemangioblastoma who underwent PET/CT scans using F-FDG and Ga-DOTATATE. The tumor showed low-level F-FDG and increased ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001511
更新日期:2017-03-01 00:00:00
abstract::Thirty gallium scans, using currently acceptable dosage levels (5-6 mCi) and a conventional rotating gamma camera, were performed on 20 patients with lymphoma or infection. Compared to planar scans, SPECT increased sensitivity and lesion detection from 48% to 89% in lymphoma, and from 50% to 80% in infection. The pred...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198709000-00003
更新日期:1987-09-01 00:00:00
abstract::A case is presented of an accessory spleen that was identified on nuclear scan at the time of diagnosis of splenic rupture. This information, proven by subsequent angiography, alerted the surgeons to the ease with which functional splenic tissue could be preserved in this patient. A sulfur colloid scan obtained post s...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198206000-00003
更新日期:1982-06-01 00:00:00