Beta rhythm events predict corticospinal motor output.

abstract：:The objective of this study was to unveil the potential mechanism of focused ultrasound (FUS)-enhanced intranasal (IN) brain drug delivery and assess its feasibility in the delivery of therapeutic molecules. Delivery outcomes of fluorescently-labeled dextrans to mouse brains by IN administration either before or after...

journal_title：Scientific reports

authors： Chen H,Yang GZ,Getachew H,Acosta C,Sierra Sánchez C,Konofagou EE

更新日期：2016-06-27 00:00:00

abstract：:The association of cabbage white butterflies (Pieris spec., Lepidoptera: Pieridae) with their glucosinolate-containing host plants represents a well-investigated example of the sequential evolution of plant defenses and insect herbivore counteradaptations. The defensive potential of glucosinolates, a group of amino ac...

journal_title：Scientific reports

authors： Steiner AM,Busching C,Vogel H,Wittstock U

更新日期：2018-07-17 00:00:00

abstract：:Although human induced pluripotent stem cell (hiPSC) lines are karyotypically normal, they retain the potential for mutation in the genome. Accordingly, intensive and relevant quality controls for clinical-grade hiPSCs remain imperative. As a conceptual approach, we performed RNA-seq-based broad-range genetic quality ...

journal_title：Scientific reports

authors： Jo HY,Han HW,Jung I,Ju JH,Park SJ,Moon S,Geum D,Kim H,Park HJ,Kim S,Stacey GN,Koo SK,Park MH,Kim JH

更新日期：2020-03-03 00:00:00

abstract：:We address the impact of the spin-orbit (SO) coupling on the localization-delocalization-transition (LDT) in a spin-orbit coupled Bose-Einstein condensate in a bichromatic potential. We find that SO coupling significantly alters the threshold depth of the one of sublattices above which the lowest eigenstates transform...

journal_title：Scientific reports

authors： Li C,Ye F,Kartashov YV,Konotop VV,Chen X

更新日期：2016-08-17 00:00:00

abstract：:Chronic consumption of excess ethanol increases the risk of colorectal cancer. The pathogenesis of ethanol-related colorectal cancer (ER-CRC) is thought to be partly mediated by gut microbes. Specifically, bacteria in the colon and rectum convert ethanol to acetaldehyde (AcH), which is carcinogenic. However, the effec...

journal_title：Scientific reports

authors： Tsuruya A,Kuwahara A,Saito Y,Yamaguchi H,Tsubo T,Suga S,Inai M,Aoki Y,Takahashi S,Tsutsumi E,Suwa Y,Morita H,Kinoshita K,Totsuka Y,Suda W,Oshima K,Hattori M,Mizukami T,Yokoyama A,Shimoyama T,Nakayama T

更新日期：2016-06-13 00:00:00

abstract：:Here we show that electrical tuning of the sensitivity of chemitransistor sensors, namely field-effect-transistors (FETs) exploiting nano/mesostructured sensing materials, can be used to effectively address two chief problems of state-of-the-art gas sensors, specifically fabrication reliability and degradation by agin...

journal_title：Scientific reports

authors： Lazzerini GM,Strambini LM,Barillaro G

更新日期：2013-01-01 00:00:00

abstract：:R.PabI is a type II restriction enzyme that recognizes the 5'-GTAC-3' sequence and belongs to the HALFPIPE superfamily. Although most restriction enzymes cleave phosphodiester bonds at specific sites by hydrolysis, R.PabI flips the guanine and adenine bases of the recognition sequence out of the DNA helix and hydrolyz...

journal_title：Scientific reports

authors： Wang D,Miyazono KI,Tanokura M

更新日期：2016-10-12 00:00:00

abstract：:Cell competition is a cell-cell interaction by which a cell compares its fitness to that of neighboring cells. The cell with the relatively lower fitness level is the "loser" and actively eliminated, while the cell with the relatively higher fitness level is the "winner" and survives. Recent studies have shown that ce...

journal_title：Scientific reports

authors： Chiba T,Ishihara E,Miyamura N,Narumi R,Kajita M,Fujita Y,Suzuki A,Ogawa Y,Nishina H

更新日期：2016-06-21 00:00:00

abstract：:Interfacial charge transfer from photoexcited ruthenium-based N3 dye molecules into ZnO thin films received controversial interpretations. To identify the physical origin for the delayed electron transfer in ZnO compared to TiO2, we probe directly the electronic structure at both dye-semiconductor interfaces by applyi...

journal_title：Scientific reports

authors： Borgwardt M,Wilke M,Kampen T,Mähl S,Xiao M,Spiccia L,Lange KM,Kiyan IY,Aziz EF

更新日期：2016-04-13 00:00:00

abstract：:Elevated ground-level ozone (O3), which is an important aspect of air quality related to public health, has been causing increasing concern. This study investigated the spatiotemporal distribution of ground-level O3 concentrations in China using a dataset from the Chinese national air quality monitoring network during...

journal_title：Scientific reports

authors： Wang WN,Cheng TH,Gu XF,Chen H,Guo H,Wang Y,Bao FW,Shi SY,Xu BR,Zuo X,Meng C,Zhang XC

更新日期：2017-06-16 00:00:00

abstract：:Sea surface temperature (SST) patterns can - as surface climate forcing - affect weather and climate at large distances. One example is El Niño-Southern Oscillation (ENSO) that causes climate anomalies around the globe via teleconnections. Although several studies identified and characterized these teleconnections, ou...

journal_title：Scientific reports

authors： Agarwal A,Caesar L,Marwan N,Maheswaran R,Merz B,Kurths J

更新日期：2019-06-19 00:00:00

abstract：:Bose Einstein condensates of spin-1 atoms are known to exist in two different phases, both having spontaneously broken spin-rotation symmetry, a ferromagnetic and a polar condensate. Here we show that in two spatial dimensions it is possible to achieve a quantum phase transition from a polar condensate into a singlet ...

journal_title：Scientific reports

authors： Chudnovskiy AL,Cheianov V

更新日期：2018-08-20 00:00:00

abstract：:The aims of this study were, firstly, to assess the effect of concurrent peripheral artery disease (PAD) on the health-related quality of life (QOL) of people diagnosed with a small abdominal aortic aneurysm (AAA); and secondly, to test whether the peroxisome proliferator-activated receptor α agonist fenofibrate impro...

journal_title：Scientific reports

authors： Golledge J,Pinchbeck J,Rowbotham SE,Yip L,Jenkins JS,Quigley F,Moxon JV

更新日期：2020-09-03 00:00:00

abstract：:Immunoaffinity enrichment of proteotypic peptides, coupled with selected reaction monitoring, enables indirect protein quantification. However the lack of suitable antibodies limits its widespread application. We developed a method in which multi-specific antibodies are used to enrich groups of peptides, thus facilita...

journal_title：Scientific reports

authors： Weiß F,Schnabel A,Planatscher H,van den Berg BH,Serschnitzki B,Nuessler AK,Thasler WE,Weiss TS,Reuss M,Stoll D,Templin MF,Joos TO,Marcus K,Poetz O

更新日期：2015-03-04 00:00:00

abstract：:Protein colocalisation is often studied using pixel intensity-based coefficients such as Pearson, Manders, Li or Costes. However, these methods cannot be used to study object-based colocalisations in biological systems. Therefore, a novel method is required to automatically identify regions of fluorescent signal in tw...

journal_title：Scientific reports

authors： Khushi M,Napier CE,Smyth CM,Reddel RR,Arthur JW

更新日期：2017-08-21 00:00:00

abstract：:Breast cancer (BC) is the leading cause of cancer death in women. Adipokines, and other inflammation molecules linked to adiposity, are suspected to be involved in breast carcinogenesis, however prospective findings are inconclusive. In a prospective nested case-control study within the EPIC-Varese cohort, we used con...

journal_title：Scientific reports

authors： Agnoli C,Grioni S,Pala V,Allione A,Matullo G,Gaetano CD,Tagliabue G,Sieri S,Krogh V

更新日期：2017-10-05 00:00:00

abstract：:Bt cotton was genetically modified to produce insecticidal proteins targeting Lepidopteran pests and is therefore only minimally affected by caterpillar damage. This could lead to reduced levels of inherent, systemically inducible defensive compounds in Bt cotton which might benefit other important cotton herbivores s...

journal_title：Scientific reports

authors： Eisenring M,Naranjo SE,Bacher S,Abbott A,Meissle M,Romeis J

更新日期：2019-02-25 00:00:00

abstract：:The objective of this study was to evaluate the stimulatory effects of Bacillus amyloliquefaciens SQR9 on dendritic cells (DCs) and to verify its ability to enhance the immune response by modulating DC maturation. The results demonstrated that B. amyloliquefaciens SQR9 can adhere to the nasal epithelium and be taken u...

journal_title：Scientific reports

authors： Huang L,Qin T,Yin Y,Gao X,Lin J,Yang Q,Yu Q

更新日期：2016-02-19 00:00:00

abstract：:Overuse of nitrogen (N) fertilizer has led to low N use efficiency (NUE) and high N loss in single rice cropping systems in southeast China. Application of controlled-release urea (CRU) is considered as an effective N fertilizer practice for improving crop yields and NUE. Here, field experiments were conducted during ...

journal_title：Scientific reports

authors： Chen Z,Wang Q,Ma J,Zou P,Jiang L

更新日期：2020-06-26 00:00:00

abstract：:The need for sensitive, robust, portable, and inexpensive biosensing platforms is of significant interest in clinical applications for disease diagnosis and treatment monitoring at the point-of-care (POC) settings. Rapid, accurate POC diagnostic assays play a crucial role in developing countries, where there are limit...

journal_title：Scientific reports

authors： Shafiee H,Asghar W,Inci F,Yuksekkaya M,Jahangir M,Zhang MH,Durmus NG,Gurkan UA,Kuritzkes DR,Demirci U

更新日期：2015-03-06 00:00:00

abstract：:Myocardial infarction (MI) can result in sympathetic nerve loss in the infarct region. However, the contribution of hypo-innervation to electrophysiological remodeling, independent from MI-induced ischemia and fibrosis, has not been comprehensively investigated. We present a novel mouse model of regional cardiac sympa...

journal_title：Scientific reports

authors： Tapa S,Wang L,Francis Stuart SD,Wang Z,Jiang Y,Habecker BA,Ripplinger CM

更新日期：2020-11-02 00:00:00

abstract：:Rapid, sensitive, point-of-care diagnostics are critical for managing infectious diseases. Here we adapt the CRISPR-based SHERLOCK method to develop a rapid, accurate, single copy detection assay for White Spot Syndrome Virus, the most devastating virus impacting global shrimp aquaculture. Further, we combine paper ma...

journal_title：Scientific reports

authors： Sullivan TJ,Dhar AK,Cruz-Flores R,Bodnar AG

更新日期：2019-12-23 00:00:00

abstract：:Nicotinamide riboside (NR) is a newly discovered nicotinamide adenine dinucleotide (NAD+) precursor vitamin. A crystal form of NR chloride termed NIAGEN is generally recognized as safe (GRAS) for use in foods and the subject of two New Dietary Ingredient Notifications for use in dietary supplements. To evaluate the ki...

journal_title：Scientific reports

authors： Conze D,Brenner C,Kruger CL

更新日期：2019-07-05 00:00:00

abstract：:Excessive tillage and soil compaction threaten the sustainable farmlands in the Huang-Huai-Hai Plains of China. Our study explores tillage practices to improve soil and root ecology and promote productivity in the winter wheat fields. We tested the impact of plowing, rotary, strip rotary tillage and strip rotary tilla...

journal_title：Scientific reports

authors： He J,Shi Y,Zhao J,Yu Z

更新日期：2019-08-12 00:00:00

abstract：:The Internet of Things is driving extensive efforts to develop intelligent everyday objects. This requires seamless integration of relatively simple electronics, for example through 'stick-on' electronics labels. We believe the future evolution of this technology will be governed by Wright's Law, which was first propo...

journal_title：Scientific reports

authors： Myny K,Smout S,Rockelé M,Bhoolokam A,Ke TH,Steudel S,Cobb B,Gulati A,Gonzalez Rodriguez F,Obata K,Marinkovic M,Pham DV,Hoppe A,Gelinck GH,Genoe J,Dehaene W,Heremans P

更新日期：2014-12-10 00:00:00

abstract：:In kidney disease, higher circulating levels of the mineral-regulating hormone fibroblast growth factor (FGF)-23 are predictive of disease progression but direct pathogenic effects on the kidney are unknown. We sought evidence of local renal synthesis in response to unilateral ureteric obstruction in the mouse, and pr...

journal_title：Scientific reports

authors： Smith ER,Tan SJ,Holt SG,Hewitson TD

更新日期：2017-06-13 00:00:00

abstract：:Fully elucidating the molecular mechanisms of non-coding RNAs (ncRNAs), including micro RNAs (miRNAs) and long non-coding RNAs (lncRNAs), underlying hepatocarcinogenesis is challenging. We characterized the expression profiles of ncRNAs and constructed a regulatory mRNA-lncRNA-miRNA (MLMI) network based on transcripto...

journal_title：Scientific reports

authors： Tang X,Feng D,Li M,Zhou J,Li X,Zhao D,Hao B,Li D,Ding K

更新日期：2019-11-06 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Ihara T,Nakamura Y,Mitsui T,Tsuchiya S,Kanda M,Kira S,Nakagomi H,Sawada N,Kamiyama M,Shigetomi E,Shinozaki Y,Yoshiyama M,Nakao A,Koizumi S,Takeda M

更新日期：2019-11-08 00:00:00

abstract：:Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and platelet count (PC) were shown to be prognostic in several solid malignancies. We analysed 603 R0 resected patients to assess whether NLR, PLR and PC correlate with other well-known prognostic factors and survival of patients with colorectal ...

journal_title：Scientific reports

authors： Pedrazzani C,Mantovani G,Fernandes E,Bagante F,Luca Salvagno G,Surci N,Campagnaro T,Ruzzenente A,Danese E,Lippi G,Guglielmi A

更新日期：2017-05-04 00:00:00

abstract：:The long-term survival of relict populations depends on the accessibility of appropriate sites (microrefugia). In recent times, due to the mass extinction of rare species that has resulted from the loss of natural habitats, the question is - Are there any human-made sites that can act as refugial habitats? We examined...

journal_title：Scientific reports

authors： Zielińska KM,Kiedrzyński M,Grzyl A,Rewicz A

更新日期：2016-08-18 00:00:00