Abstract:
:Aim: We assessed reporting of data on sex/gender and race/ethnicity in randomized controlled trials of interventions published in the highest-ranking anesthesiology journals from 2014 to 2017. Methods: We extracted data regarding terminology for sex/gender, proportion of participants according to the race/gender and race/ethnicity, and results shown for the race/gender and race/ethnicity. Results: Among the analyzed 732 trials, few stratified allocation of participants on the basis of sex/gender and race/ethnicity, few reported results for sex/gender or race/ethnicity and the outcomes reported may be influenced by one or both. Conclusion: In conclusion, outcomes of anesthesiology trials could be vulnerable to an important and avoidable source of bias; trialists need to pay more attention to sex and race/ethnicity when designing and reporting their studies.
journal_name
J Comp Eff Resjournal_title
Journal of comparative effectiveness researchauthors
Begic D,Janda-Martinac C,Vrdoljak M,Puljak Ldoi
10.2217/cer-2019-0071subject
Has Abstractpub_date
2019-12-01 00:00:00pages
1417-1423issue
16eissn
2042-6305issn
2042-6313journal_volume
8pub_type
杂志文章abstract:AIM:We conducted a meta-analysis to compare the efficacy and safety of oral and intravenous applications of tranexamic acid (TXA) in total hip arthroplasty (THA). MATERIALS & METHODS:Electronic databases, including PubMed, Cochrane CENTRAL, ScienceDirect and Embase, were searched to identify the studies comparing the ...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章,meta分析
doi:10.2217/cer-2018-0120
更新日期:2019-04-01 00:00:00
abstract:AIM:Explore perspectives of adolescent and young adult (AYA) and parent stakeholders regarding their engagement in comparative effectiveness research (CER) evaluating cholesterol screening and treatment strategies for 17-21 year olds. METHODS:All nine AYAs and parent stakeholders participating in a 20-member panel of ...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2016-0025
更新日期:2016-08-01 00:00:00
abstract:AIM:Current stroke severity scales cannot be used for archival data. We develop and validate a measure of stroke severity at hospital discharge (Stroke Administrative Severity Index [SASI]) for use in billing data. METHODS:We used the NIH Stroke Scale (NIHSS) as the theoretical framework and identified 285 relevant In...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2017-0058
更新日期:2018-04-01 00:00:00
abstract:AIM:To provide an overview of thresholds for incremental cost-effectiveness ratios (ICERs) representing willingness-to-pay (WTP) across multiple countries and insights into exemptions pertaining to the ICER (e.g., cancer). To compare ICER thresholds to individual country's estimated ability-to-pay. MATERIALS & METHODS...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer.15.38
更新日期:2015-09-01 00:00:00
abstract::Aim: To evaluate the patterns of cancer patients-assessed quality of outpatient care in the USA. Materials & methods: Medical Expenditure Panel Survey datasets for the years 2011, 2013, 2015 and 2017 were accessed and adult participants with a history of cancer diagnosis were reviewed. Participants' assessments of dif...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2020-0124
更新日期:2020-09-01 00:00:00
abstract::Aim: To compare efficacy between total gastrectomy (TG) and proximal gastrectomy (PG) for upper-third gastric cancer. Materials & methods: PubMed, Embase and Cochrane library were searched to select suitable researches. Stata was used for meta-analysis including 5-year overall survival rate, recurrence rate, complicat...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章,meta分析
doi:10.2217/cer-2019-0016
更新日期:2019-07-01 00:00:00
abstract:AIM:Develop an accessible exercise to engage underserved populations about research funding priorities; analyze the criteria they use to prioritize research; contrast these criteria to those currently used by Patient Centered Outcomes Research Institute (PCORI). MATERIALS & METHODS:Academic and community partners coll...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2017-0008
更新日期:2017-07-01 00:00:00
abstract::Degenerative spine disorders are a significant cause of patient morbidity and are a prominent factor in healthcare costs in many countries. Pressure for healthcare cost control and the desire for improved outcomes have led to an expanding emphasis on evidence-based medicine methodologies in spine research. Determinati...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章,评审
doi:10.2217/cer.12.73
更新日期:2013-01-01 00:00:00
abstract::Aim: Increasing use of selective serotonin-reuptake inhibitors (SSRIs) in Scotland, coupled with safety concerns with some SSRIs, and the increasing availability of generic SSRIs, have resulted in multiple initiatives to improve the quality and efficiency of their prescribing in Scotland. Our aim is to assess their in...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2018-0132
更新日期:2019-05-01 00:00:00
abstract:AIM:Reducing the fluctuation of blood pressure has recently been recognized as a potential target for improving management of hypertension to prevent cardiovascular events, particularly for strokes. Some randomized controlled trials demonstrated that amlodipine can effectively reduce blood pressure as a well-establishe...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章,多中心研究
doi:10.2217/cer-2017-0063
更新日期:2018-07-01 00:00:00
abstract::Patients with acute coronary syndromes and severe multivessel or left main coronary artery disease have better outcomes when prompt revascularization is performed in addition to optimal medical therapy (OMT). However, in patients with stable ischemic heart disease, randomized strategy trials have revealed equipoise be...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章,评审
doi:10.2217/cer.15.37
更新日期:2015-09-01 00:00:00
abstract::The COVID-19 pandemic is revealing the unacceptable health disparities across New York City and in this country. The mortality rates of vulnerable and minority populations alone suggest a need to re-evaluate clinical decision making protocols, especially given the recently passed Emergency or Disaster Treatment Protec...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2020-0090
更新日期:2020-08-01 00:00:00
abstract:AIM:The importance of adjusting for cross-study heterogeneity when conducting network meta-analyses (NMAs) was demonstrated using a case study of biologic therapies for moderate-to-severe plaque psoriasis. METHODS:Bayesian NMAs were conducted for Psoriasis Area and Severity Index 90 response. Several covariates were c...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2018-0065
更新日期:2018-11-01 00:00:00
abstract:AIM:Many hepatitis C virus regimens are unlikely to be compared head to head. In more difficult to treat populations where there is no standard of care, trials are single arm. We describe a flexible meta-analysis platform in this setting. METHODS:Our meta-analysis is literature based. We illustrate our methodology and...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章,meta分析,评审
doi:10.2217/cer.14.69
更新日期:2015-03-01 00:00:00
abstract:AIM:GNE myopathy, a rare, severe, progressive myopathy, presents with lower extremity distal muscle weakness. The GNE myopathy functional activity scale (GNEM-FAS) evaluates the impact of GNE myopathy on functioning in adults. This paper presents the psychometric validation of the GNEM-FAS. PATIENTS & METHODS:Validati...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2017-0062
更新日期:2018-04-01 00:00:00
abstract::Translation of medical evidence into practice has not kept pace with the growth of medical technology and knowledge. We present three case studies--statins, drug eluting stents and bone marrow transplantation for breast cancer--to propose a framework for describing five factors that may influence the rate of adoption....
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer.13.39
更新日期:2013-07-01 00:00:00
abstract:AIM:Laboratory test (lab) results may be useful to detect incident diabetes in electronic health record and claims-based studies. RESEARCH DESIGN & METHODS:Using the Mini-Sentinel distributed database, we assessed the value of lab results added to diagnosis codes and dispensing claims to identify incident diabetes. R...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2016-0033
更新日期:2017-01-01 00:00:00
abstract::Aim: Medicaid versus private primary insurance status may predict in-hospital mortality and morbidity after total knee arthroplasty (TKA). Materials & methods: Regression models were used to test our hypothesis in patients in the State Inpatient Database (SID) from five states who underwent primary TKA from January 20...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2019-0027
更新日期:2019-10-01 00:00:00
abstract::Concerted efforts are underway to improve healthcare decision-making through patient-centered outcomes research. These efforts are supported by the Patient-Centered Outcomes Research Trust Fund, which was established within the Patient Protection and Affordable Care Act. This article focuses on describing national dat...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer.14.54
更新日期:2015-01-01 00:00:00
abstract:AIM:Studies on multiple sclerosis in Saudi Arabia remain scant, particularly studies on the psychological aspects. This study measures severities of depression, anxiety and stress, and compares them to the used disease-modifying treatment. MATERIALS & METHODS:Cross-sectional study using a phone questionnaire targeting...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章,多中心研究
doi:10.2217/cer-2016-0087
更新日期:2017-07-01 00:00:00
abstract::Aim: Breast cancer is a leading cause of cancer among women. Because guidelines on screening for breast cancer for certain ages are controversial, many experts advocate the use of shared decision making (SDM) using validated decision aids (DAs). Recent studies have concluded that DAs are beneficial; however, the resul...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2020-0052
更新日期:2020-10-01 00:00:00
abstract::Evaluation of: Olanow CW, Kieburtz K, Odin P et al. Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study. Lancet Neurol. 13(2), 141-149 (2014). Levodopa-induced motor complications, including mot...
journal_title:Journal of comparative effectiveness research
pub_type: 评论,杂志文章
doi:10.2217/cer.14.33
更新日期:2014-07-01 00:00:00
abstract::Aim: The systematic review assessed the effect of mindfulness-based interventions on the quality of life among women with breast cancer. Methods: PubMed, Cochrane library, EMBASE, Web of Science and CINAHL databases were searched for studies published. Our review assessed the effect of mindfulness-based interventions ...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2019-0053
更新日期:2019-08-01 00:00:00
abstract::Aim: Dedicated brain imaging is advocated by the National Comprehensive Cancer Network guidelines for newly diagnosed non-small-cell cancer (NSCLC) patients beyond stage I. The current study assessed the performance characteristics of this recommendation. Methods: Through accessing the Surveillance, Epidemiology and E...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer-2018-0148
更新日期:2019-06-01 00:00:00
abstract::The 11 big health data networks participating in the AcademyHealth Electronic Data Methods Forum represent cutting-edge efforts to harness the power of big health data for research and quality improvement. This paper is a comparative case study based on site visits conducted with a subset of these large infrastructure...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer.14.72
更新日期:2014-11-01 00:00:00
abstract:AIM:To identify ongoing practices and opportunities for improving national comparative effectiveness research (CER) translation through dissemination and implementation (D&I) via NIH-funded Clinical and Translational Science Award (CTSA) institutions. MATERIALS & METHODS:Key informant interviews were conducted with 18...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer.13.10
更新日期:2013-03-01 00:00:00
abstract:AIMS:This study aimed to identify methods to engage hard-to-reach patients in the research process. MATERIALS & METHODS:With funding from the Patient-Centered Outcomes Research Institute (Washington, DC, USA), the University of Maryland (MD, USA) conducted 20 focus groups and one individual interview. The sample consi...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章
doi:10.2217/cer.13.11
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Palliative cancer patients often require clinic or hospital follow-up after any treatment intervention they may have received. This is typically done in person at either a hospital or a clinic. In these advanced cancer patients, this may be burdensome and result in attrition. Telephone follow-up is becoming ...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章,评审
doi:10.2217/cer.12.63
更新日期:2012-11-01 00:00:00
abstract::Comparative effectiveness research (CER) calls for substantial changes in the way clinical research is conducted, interpreted and practically applied in the USA, in order to produce useful clinical evidence. Departing from classic efficacy and effectiveness research, the evolving CER paradigm requires structural and s...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章,评审
doi:10.2217/CER.12.23
更新日期:2012-05-01 00:00:00
abstract:AIM:Compare the safety and efficacy of intermittent fenofibrate versus simvastatin in chronic hemodialysis patients. PATIENTS & METHODS:Sixty patients received either fenofibrate 100 mg or simvastatin 20 mg after their dialysis session (parallel study). The safety and efficacy of drugs on lipid profile, oxidized low-d...
journal_title:Journal of comparative effectiveness research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2217/cer-2016-0076
更新日期:2017-07-01 00:00:00