Organic Molecule Detection Based on SERS in Microfluidics.

abstract：:Schiff-based complexes as a source of cancer chemotherapeutic compounds have been subjected to the variety of anticancer studies. The in-vitro analysis confirmed the CdCl2(C14H21N3O2) complex possess cytotoxicity and apoptosis induction properties in colon cancer cells, so lead to investigate the inhibitory efficiency...

journal_title：Scientific reports

authors： Hajrezaie M,Shams K,Moghadamtousi SZ,Karimian H,Hassandarvish P,Emtyazjoo M,Zahedifard M,Majid NA,Mohd Ali H,Abdulla MA

更新日期：2015-07-23 00:00:00

abstract：:Two essential key events in acrylamide (ACR) acute neurotoxicity are the formation of adducts with nucleophilic sulfhydryl groups on cysteine residues of selected proteins in the synaptic terminals and the depletion of the glutathione (GSx) stores in neural tissue. The use of N-acetylcysteine (NAC) has been recently p...

journal_title：Scientific reports

authors： Faria M,Prats E,Gómez-Canela C,Hsu CY,Arick MA 2nd,Bedrossiantz J,Orozco M,Garcia-Reyero N,Ziv T,Ben-Lulu S,Admon A,Gómez-Oliván LM,Raldúa D

更新日期：2019-11-11 00:00:00

abstract：:Solution-processed gate dielectrics were fabricated with the combined ZrO2 and Al2O3 (ZAO) in the form of mixed and stacked types for oxide thin film transistors (TFTs). ZAO thin films prepared with double coatings for solid gate dielectrics were characterized by analytical tools. For the first time, the capacitance o...

journal_title：Scientific reports

authors： Kim H,Kwack YJ,Yun EJ,Choi WS

更新日期：2016-09-19 00:00:00

abstract：:Modification of lattice thermal conductivity (κL) of a solid by means of hydrostatic pressure (P) has been a crucially interesting approach that targets a broad range of advanced materials from thermoelectrics and thermal insulators to minerals in mantle. Although it is well documented knowledge that thermal conductiv...

journal_title：Scientific reports

authors： Luo Y,Wang J,Li Y,Wang J

更新日期：2016-07-19 00:00:00

abstract：:Over the last decades, great strides were made in the development of novel implants for the treatment of bone defects. The increasing versatility and complexity of these implant designs request for concurrent advances in means to assess in vivo the course of induced bone formation in preclinical models. Since its disc...

journal_title：Scientific reports

authors： Lienemann PS,Metzger S,Kiveliö AS,Blanc A,Papageorgiou P,Astolfo A,Pinzer BR,Cinelli P,Weber FE,Schibli R,Béhé M,Ehrbar M

更新日期：2015-05-19 00:00:00

abstract：:Giant spin Hall effect (GSHE) has received significant attention for its potential in future spintronic applications. Spin current via GSHE-based thin films provides an effective and promising means to manipulate magnetization. However, an external in-plane magnetic field is required to consistently switch the perpend...

journal_title：Scientific reports

authors： Chen W,Qian L,Xiao G

更新日期：2018-05-25 00:00:00

abstract：:For the first time, high-surface-area (approximately 1465 m(2) g(-1)), highly porous and heteroatom-enriched activated carbon (HAC) was prepared from banana stems (Musa paradisiaca, Family: Musaceae) at different carbonization temperatures of 700, 800 and 900 °C (HAC) using a simple and eco-friendly method. The amount...

journal_title：Scientific reports

authors： Madhu R,Veeramani V,Chen SM

更新日期：2014-04-23 00:00:00

abstract：:Methylated non-CpGs (mCpH; H means A, C, and T) have emerged as key epigenetic marks in mammalian embryonic stem cells (ESCs) and neurons, regulating cell type-specific functions. In these two cell types, mCpHs show distinct motifs and correlations to transcription that could be a key in understanding the cell type-sp...

journal_title：Scientific reports

authors： Lee JH,Park SJ,Nakai K

更新日期：2017-09-12 00:00:00

abstract：:Raman spectroscopy is a powerful analytical method that allows deposited and/or immobilized cells to be evaluated without complex sample preparation or labeling. However, a main limitation of Raman spectroscopy in cell analysis is the extremely weak Raman intensity that results in low signal to noise ratios. Therefore...

journal_title：Scientific reports

authors： Mikoliunaite L,Rodriguez RD,Sheremet E,Kolchuzhin V,Mehner J,Ramanavicius A,Zahn DR

更新日期：2015-08-27 00:00:00

abstract：:We investigated whether clinical factors including comorbidities, medications, and laboratory results predict inpatient fall risk in older adults. The participants in this case-control study included hospitalized older adults with acute conditions who had falls during their hospital stay (case group) and 410 hospitali...

journal_title：Scientific reports

authors： Noh HM,Song HJ,Park YS,Han J,Roh YK

更新日期：2021-01-15 00:00:00

abstract：:The symmetrically stable craniofacial bony structure supports the complex functions and delicate contour of the face. Congenital craniofacial deformities are often accompanied by bony defects and have been repetitively correlated with compromised dento-maxillary stability, but neither the extent nor the pattern of cle...

journal_title：Scientific reports

authors： Luo X,Huang H,Yin X,Shi B,Li J

更新日期：2019-03-12 00:00:00

abstract：:M2BP (also called 90K) is an interferon-stimulated gene product that is upregulated in HIV-1 infection. A recent study revealed that M2BP reduces the infectivity of HIV-1 by inhibiting the processing of the viral envelope protein. Here we report that in addition to reducing viral infectivity, M2BP inhibits HIV-1 virio...

journal_title：Scientific reports

authors： Wang Q,Zhang X,Han Y,Wang X,Gao G

更新日期：2016-09-08 00:00:00

abstract：:Nanocrystals of Ln3+ (Ln = Yb, Tm and Ho) doped β-NaLuF4 with average diameter about 200 nm are dispersed in silica-based microtube (MT) by a simple flame heating method. The fabricated microtube has a diameter range from 2 μm to 30 μm and lengths up to hundreds microns. The fluorescence of upconversion nanocrystals (...

journal_title：Scientific reports

authors： Li H,Wang Y,Li H,Zhang Y,Yang J

更新日期：2016-10-25 00:00:00

abstract：:Pentameric ligand-gated ion channels (pLGICs) are targets of general anesthetics, but molecular mechanisms underlying anesthetic action remain debatable. We found that ELIC, a pLGIC from Erwinia chrysanthemi, can be functionally inhibited by isoflurane and other anesthetics. Structures of ELIC co-crystallized with iso...

journal_title：Scientific reports

authors： Chen Q,Kinde MN,Arjunan P,Wells MM,Cohen AE,Xu Y,Tang P

更新日期：2015-09-08 00:00:00

abstract：:Mucociliary clearance is a biomechanical mechanism of airway protection. It consists of the active transport along the bronchial tree of the mucus, a fluid propelled by the coordinated beating of a myriad of cilia on the epithelial surface of the respiratory tract. The physics of mucus transport is poorly understood b...

journal_title：Scientific reports

authors： Khelloufi MK,Loiseau E,Jaeger M,Molinari N,Chanez P,Gras D,Viallat A

更新日期：2018-02-05 00:00:00

abstract：:Therapies that target the signal transduction and metabolic pathways of cancer stem cells (CSCs) are innovative strategies to effectively reduce the recurrence and significantly improve the outcome of glioblastoma multiforme (GBM). CSCs exhibit an increased rate of glycolysis, thus rendering them intrinsically more se...

journal_title：Scientific reports

authors： Daniele S,Giacomelli C,Zappelli E,Granchi C,Trincavelli ML,Minutolo F,Martini C

更新日期：2015-10-23 00:00:00

abstract：:We show that ATM kinase inhibition using AZ31 prior to 9 or 9.25 Gy total body irradiation (TBI) reduced median time to moribund in mice to 8 days. ATR kinase inhibition using AZD6738 prior to TBI did not reduce median time to moribund. The striking finding associated with ATM inhibition prior to TBI was increased cry...

journal_title：Scientific reports

authors： Vendetti FP,Leibowitz BJ,Barnes J,Schamus S,Kiesel BF,Abberbock S,Conrads T,Clump DA,Cadogan E,O'Connor MJ,Yu J,Beumer JH,Bakkenist CJ

更新日期：2017-02-01 00:00:00

abstract：:High mobility channel thin-film-transistor (TFT) is crucial for both display and future generation integrated circuit. We report a new metal-oxide TFT that has an ultra-thin 4.5 nm SnO2 thickness for both active channel and source-drain regions, very high 147 cm(2)/Vs field-effect mobility, high ION/IOFF of 2.3 × 10(7...

journal_title：Scientific reports

authors： Shih CW,Chin A,Lu CF,Su WF

更新日期：2016-01-08 00:00:00

abstract：:Diabetic Retinopathy, the main cause of visual loss and blindness among working population, is a complication of Diabetes mellitus (DM), which has been described as a major public health challenge, so it is important to identify biomarkers to predict and to stratify patient´s possibility for developing DR. MicroRNAs (...

journal_title：Scientific reports

authors： Prado MSG,de Goes TC,de Jesus ML,Mendonça LSO,Nascimento JS,Kaneto CM

更新日期：2019-12-23 00:00:00

abstract：:This study was to evaluate the effect of Epigallocatechin-3-gallate (EGCG) on the bond strength of two adhesive systems to the Sodium hypochlorite (NaOCl) treated intraradicular dentin. The roots were accepted regular root canal treatments and post space preparations, and further divided into eight groups according to...

journal_title：Scientific reports

authors： Yu HH,Zhang L,Xu S,Li F,Yu F,Liu ZY,Huang L,Chen JH

更新日期：2017-06-26 00:00:00

abstract：:Mitofusins are large transmembrane GTPases of the dynamin-related protein family, and are required for the tethering and fusion of mitochondrial outer membranes. Their full-length structures remain unknown, which is a limiting factor in the study of outer membrane fusion. We investigated the structure and dynamics of ...

journal_title：Scientific reports

authors： De Vecchis D,Cavellini L,Baaden M,Hénin J,Cohen MM,Taly A

更新日期：2017-08-31 00:00:00

abstract：:Malignant transformation results in increased levels of reactive oxygen species (ROS). Adaption to this toxic stress allows cancer cells to proliferate. Recently, piperlongumine (PL), a natural alkaloid, was identified to exhibit novel anticancer effects by targeting ROS signaling. PL induces apoptosis specifically in...

journal_title：Scientific reports

authors： Li J,Sharkey CC,King MR

更新日期：2015-05-18 00:00:00

abstract：:Accurate repair of DNA damage is crucial to ensure genome stability and cell survival of all organisms. Bile functions as a defensive barrier against intestinal colonization by pathogenic microbes. Campylobacter jejuni, a leading bacterial cause of foodborne illness, possess strategies to mitigate the toxic components...

journal_title：Scientific reports

authors： Gourley CR,Negretti NM,Konkel ME

更新日期：2017-10-31 00:00:00

abstract：:Human papillomaviruses enter host cells via a clathrin-independent endocytic pathway involving tetraspanin proteins. However, post-endocytic trafficking required for virus capsid disassembly remains unclear. Here we demonstrate that the early trafficking pathway of internalised HPV particles involves tetraspanin CD63,...

journal_title：Scientific reports

authors： Gräßel L,Fast LA,Scheffer KD,Boukhallouk F,Spoden GA,Tenzer S,Boller K,Bago R,Rajesh S,Overduin M,Berditchevski F,Florin L

更新日期：2016-08-31 00:00:00

abstract：:Our previous studies demonstrated that volatile oil from saussurea lappa root (VOSL), rich in two natural sesquiterpene lactones, costunolide (Cos) and dehydrocostuslactone (Dehy), exerts better anti-breast cancer efficacy and lower side effects than Cos or Dehy alone in vivo, however, their anti-cancer molecular mech...

journal_title：Scientific reports

authors： Peng Z,Wang Y,Fan J,Lin X,Liu C,Xu Y,Ji W,Yan C,Su C

更新日期：2017-01-24 00:00:00

abstract：:Rheumatoid arthritis (RA) patients have been observed to be at a lower risk of developing Alzheimer's Disease (AD). Clinical trials have showed no relationship between nonsteroidal anti-inflammatory drug (NSAID) use and AD. The aim of this study was to establish if there is a causal link between RA and AD. A systemati...

journal_title：Scientific reports

authors： Policicchio S,Ahmad AN,Powell JF,Proitsi P

更新日期：2017-10-09 00:00:00

abstract：:Balancing stomata-dependent CO2 assimilation and transpiration is a key challenge for increasing crop productivity and water use efficiency under drought stress for sustainable crop production worldwide. Here, we show that cucumber and luffa plants with luffa as rootstock have intrinsically increased water use efficie...

journal_title：Scientific reports

authors： Liu S,Li H,Lv X,Ahammed GJ,Xia X,Zhou J,Shi K,Asami T,Yu J,Zhou Y

更新日期：2016-02-02 00:00:00

abstract：:Human NAD-dependent isocitrate dehydrogenase catalyzes the decarboxylation of isocitrate (ICT) into α-ketoglutarate in the Krebs cycle. It exists as the α2βγ heterotetramer composed of the αβ and αγ heterodimers. Previously, we have demonstrated biochemically that the α2βγ heterotetramer and αγ heterodimer can be allo...

journal_title：Scientific reports

authors： Ma T,Peng Y,Huang W,Ding J

更新日期：2017-01-18 00:00:00

abstract：:Diabrotica virgifera virgifera LeConte, the western corn rootworm (WCR), is the most destructive pest of maize in North America, and has recently spread across central Europe. Its subterranean larval stages are hard to reach with pesticides and it has evolved resistance to conventional management practices. The applic...

journal_title：Scientific reports

authors： Jaffuel G,Imperiali N,Shelby K,Campos-Herrera R,Geisert R,Maurhofer M,Loper J,Keel C,Turlings TCJ,Hibbard BE

更新日期：2019-02-28 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) and cytokeratin 18 (CK18) were previously reported to be elevated in nonalcoholic fatty liver disease (NAFLD). We aim to analyze the differential roles of FGF21, cell apoptosis marker CK18 fragment M30 and total cell death marker CK18 M65ED in monitoring the different stages of NAFL...

journal_title：Scientific reports

authors： Wu G,Li H,Fang Q,Zhang J,Zhang M,Zhang L,Wu L,Hou X,Lu J,Bao Y,Jia W

更新日期：2017-07-11 00:00:00