Author Correction: Puma genomes from North and South America provide insights into the genomic consequences of inbreeding.

abstract：:One of the main reasons why nonlinear-optical signal processing (regeneration, logic, etc.) has not yet become a practical alternative to electronic processing is that the all-optical elements with nonlinear input-output relationship have remained inherently single-channel devices (just like their electronic counterpa...

journal_title：Nature communications

authors： Li L,Patki PG,Kwon YB,Stelmakh V,Campbell BD,Annamalai M,Lakoba TI,Vasilyev M

更新日期：2017-10-12 00:00:00

abstract：:To overcome the fundamental challenge of the weak natural response of antiferromagnetic materials under a magnetic field, voltage manipulation of antiferromagnetic interaction is developed to realize ultrafast, high-density, and power efficient antiferromagnetic spintronics. Here, we report a low voltage modulation of...

journal_title：Nature communications

authors： Yang Q,Wang L,Zhou Z,Wang L,Zhang Y,Zhao S,Dong G,Cheng Y,Min T,Hu Z,Chen W,Xia K,Liu M

更新日期：2018-03-07 00:00:00

abstract：:Late-onset Alzheimer's disease (AD) can, in part, be considered a metabolic disease. Besides age, female sex and APOE ε4 genotype represent strong risk factors for AD that also give rise to large metabolic differences. We systematically investigated group-specific metabolic alterations by conducting stratified associa...

journal_title：Nature communications

authors： Arnold M,Nho K,Kueider-Paisley A,Massaro T,Huynh K,Brauner B,MahmoudianDehkordi S,Louie G,Moseley MA,Thompson JW,John-Williams LS,Tenenbaum JD,Blach C,Chang R,Brinton RD,Baillie R,Han X,Trojanowski JQ,Shaw LM,Martin

更新日期：2020-03-02 00:00:00

abstract：:Chronic inflammation has been proposed as having a prominent role in the construction of social inequalities in health. Disentangling the effects of early life and adulthood social disadvantage on inflammation is key in elucidating biological mechanisms underlying socioeconomic disparities. Here we explore the relatio...

journal_title：Nature communications

authors： Berger E,Castagné R,Chadeau-Hyam M,Bochud M,d'Errico A,Gandini M,Karimi M,Kivimäki M,Krogh V,Marmot M,Panico S,Preisig M,Ricceri F,Sacerdote C,Steptoe A,Stringhini S,Tumino R,Vineis P,Delpierre C,Kelly-Irving M

更新日期：2019-02-15 00:00:00

abstract：:Sustainable food production in the context of climate change necessitates diversification of agriculture and a more efficient utilization of plant genetic resources. Fonio millet (Digitaria exilis) is an orphan African cereal crop with a great potential for dryland agriculture. Here, we establish high-quality genomic ...

journal_title：Nature communications

authors： Abrouk M,Ahmed HI,Cubry P,Šimoníková D,Cauet S,Pailles Y,Bettgenhaeuser J,Gapa L,Scarcelli N,Couderc M,Zekraoui L,Kathiresan N,Čížková J,Hřibová E,Doležel J,Arribat S,Bergès H,Wieringa JJ,Gueye M,Kane NA,Leclerc C

更新日期：2020-09-08 00:00:00

abstract：:Cytidine base editors (CBEs) and adenine base editors (ABEs), composed of a cytidine deaminase or an evolved adenine deaminase fused to Cas9 nickase, enable the conversion of C·G to T·A or A·T to G·C base pair in organisms, respectively. Here, we show that BE3 and ABE7.10 systems can achieve a targeted mutation effici...

journal_title：Nature communications

authors： Liu Z,Chen M,Chen S,Deng J,Song Y,Lai L,Li Z

更新日期：2018-07-13 00:00:00

abstract：:Cyclic GMP-AMP synthase (cGAS) is the primary sensor for aberrant intracellular dsDNA producing the cyclic dinucleotide cGAMP, a second messenger initiating cytokine production in subsets of myeloid lineage cell types. Therefore, inhibition of the enzyme cGAS may act anti-inflammatory. Here we report the discovery of ...

journal_title：Nature communications

authors： Lama L,Adura C,Xie W,Tomita D,Kamei T,Kuryavyi V,Gogakos T,Steinberg JI,Miller M,Ramos-Espiritu L,Asano Y,Hashizume S,Aida J,Imaeda T,Okamoto R,Jennings AJ,Michino M,Kuroita T,Stamford A,Gao P,Meinke P,Glickman

更新日期：2019-05-21 00:00:00

abstract：:Amazonian Dark Earths (ADEs) are unusually fertile soils characterised by elevated concentrations of microscopic charcoal particles, which confer their distinctive colouration. Frequent occurrences of pre-Columbian artefacts at ADE sites led to their ubiquitous classification as Anthrosols (soils of anthropic origin)....

journal_title：Nature communications

authors： Silva LCR,Corrêa RS,Wright JL,Bomfim B,Hendricks L,Gavin DG,Muniz AW,Martins GC,Motta ACV,Barbosa JZ,Melo VF,Young SD,Broadley MR,Santos RV

更新日期：2021-01-04 00:00:00

abstract：:Due to the generally delocalized nature of molecular valence orbitals, valence-shell spectroscopies do not usually allow to specifically target a selected atom in a molecule. However, in X-ray electron spectroscopy, the photoelectron momentum is large and the recoil angular momentum transferred to the molecule is larg...

journal_title：Nature communications

authors： Miron C,Miao Q,Nicolas C,Bozek JD,Andrałojć W,Patanen M,Simões G,Travnikova O,Ågren H,Gel'mukhanov F

更新日期：2014-05-09 00:00:00

abstract：:A challenge for neuroscience is to understand the conscious and unconscious processes underlying construction of willed actions. We investigated the neural substrate of human motor awareness during awake brain surgery. In a first experiment, awake patients performed a voluntary hand motor task and verbally monitored t...

journal_title：Nature communications

authors： Fornia L,Puglisi G,Leonetti A,Bello L,Berti A,Cerri G,Garbarini F

更新日期：2020-02-04 00:00:00

abstract：:Osteoporosis is a devastating disease with an essential genetic component. GWAS have discovered genetic signals robustly associated with bone mineral density (BMD), but not the precise localization of effector genes. Here, we carry out physical and direct variant to gene mapping in human mesenchymal progenitor cell-de...

journal_title：Nature communications

authors： Chesi A,Wagley Y,Johnson ME,Manduchi E,Su C,Lu S,Leonard ME,Hodge KM,Pippin JA,Hankenson KD,Wells AD,Grant SFA

更新日期：2019-03-19 00:00:00

abstract：:Ruddlesden-Popper halide perovskites are 2D solution-processed quantum wells with a general formula A2A'n-1M n X3n+1, where optoelectronic properties can be tuned by varying the perovskite layer thickness (n-value), and have recently emerged as efficient semiconductors with technologically relevant stability. However,...

journal_title：Nature communications

authors： Blancon JC,Stier AV,Tsai H,Nie W,Stoumpos CC,Traoré B,Pedesseau L,Kepenekian M,Katsutani F,Noe GT,Kono J,Tretiak S,Crooker SA,Katan C,Kanatzidis MG,Crochet JJ,Even J,Mohite AD

更新日期：2018-06-08 00:00:00

abstract：:Radiofrequency switches are critical components in wireless communication systems and consumer electronics. Emerging devices include switches based on microelectromechanical systems and phase-change materials. However, these devices suffer from disadvantages such as large physical dimensions and high actuation voltage...

journal_title：Nature communications

authors： Pi S,Ghadiri-Sadrabadi M,Bardin JC,Xia Q

更新日期：2015-06-25 00:00:00

abstract：:Dynamics of molecules in the solid state holds promise for connecting molecular behaviors with properties of bulk materials. Solid-state dynamics of [60]fullerene (C60) is controlled by intimate intermolecular contacts and results in restricted motions of a ratchet phase at low temperatures. Manipulation of the solid-...

journal_title：Nature communications

authors： Matsuno T,Nakai Y,Sato S,Maniwa Y,Isobe H

更新日期：2018-05-15 00:00:00

abstract：:Intestinal intraepithelial T cells contribute to the regulation of inflammatory responses in the intestine; however, the molecular basis for their development and maintenance is unknown. The aryl hydrocarbon receptor complexes with the aryl hydrocarbon receptor nuclear translocator (ARNT) and senses environmental fact...

journal_title：Nature communications

authors： Nakajima K,Maekawa Y,Kataoka K,Ishifune C,Nishida J,Arimochi H,Kitamura A,Yoshimoto T,Tomita S,Nagahiro S,Yasutomo K

更新日期：2013-01-01 00:00:00

abstract：:The application of electron microscopy to hydrated biological samples has been limited by high-vacuum operating conditions. Traditional methods utilize harsh and laborious sample dehydration procedures, often leading to structural artefacts and creating difficulties for correlating results with high-resolution fluores...

journal_title：Nature communications

authors： Wojcik M,Hauser M,Li W,Moon S,Xu K

更新日期：2015-06-11 00:00:00

abstract：:With the development of ultrafast electron and X-ray sources it is becoming possible to study structural dynamics with atomic-level spatial and temporal resolution. Because of their short mean free path, electrons are particularly well suited for investigating surfaces and thin films, such as the challenging and impor...

journal_title：Nature communications

authors： Engelen WJ,van der Heijden MA,Bakker DJ,Vredenbregt EJ,Luiten OJ

更新日期：2013-01-01 00:00:00

abstract：:The worldwide biodiversity crisis has intensified the need to better understand how biodiversity and human disturbance are related. The 'intermediate disturbance hypothesis' suggests that disturbance regimes generate predictable non-linear patterns in species richness. Evidence often contradicts intermediate disturban...

journal_title：Nature communications

authors： Mayor SJ,Cahill JF Jr,He F,Sólymos P,Boutin S

更新日期：2012-01-01 00:00:00

abstract：:Flexible organic memory devices are one of the integral components for future flexible organic electronics. However, high-density all-organic memory cell arrays on malleable substrates without cross-talk have not been demonstrated because of difficulties in their fabrication and relatively poor performances to date. H...

journal_title：Nature communications

authors： Ji Y,Zeigler DF,Lee DS,Choi H,Jen AK,Ko HC,Kim TW

更新日期：2013-01-01 00:00:00

abstract：:Schizophrenia and bipolar disorder are major psychiatric disorders with high heritability and overlapping genetic variance. Here we perform a genome-wide association study in an ethnically homogeneous cohort of 904 schizophrenia cases and 1,640 controls drawn from the Ashkenazi Jewish population. We identify a novel g...

journal_title：Nature communications

authors： Lencz T,Guha S,Liu C,Rosenfeld J,Mukherjee S,DeRosse P,John M,Cheng L,Zhang C,Badner JA,Ikeda M,Iwata N,Cichon S,Rietschel M,Nöthen MM,Cheng AT,Hodgkinson C,Yuan Q,Kane JM,Lee AT,Pisanté A,Gregersen PK,Pe'er I

更新日期：2013-01-01 00:00:00

abstract：:The interpretation of molecular vibrational spectroscopic signals in terms of atomic motion is essential to understand molecular mechanisms and for chemical characterization. The signals are usually assigned after harmonic normal mode analysis, even if molecular vibrations are known to be anharmonic. Here we obtain th...

journal_title：Nature communications

authors： Aieta C,Micciarelli M,Bertaina G,Ceotto M

更新日期：2020-08-28 00:00:00

abstract：:Innate immune signaling through the NLRP3 inflammasome is activated by multiple diabetes-related stressors, but whether targeting the inflammasome is beneficial for diabetes is still unclear. Nucleoside reverse-transcriptase inhibitors (NRTI), drugs approved to treat HIV-1 and hepatitis B infections, also block inflam...

journal_title：Nature communications

authors： Ambati J,Magagnoli J,Leung H,Wang SB,Andrews CA,Fu D,Pandey A,Sahu S,Narendran S,Hirahara S,Fukuda S,Sun J,Pandya L,Ambati M,Pereira F,Varshney A,Cummings T,Hardin JW,Edun B,Bennett CL,Ambati K,Fowler BJ,Kerur

更新日期：2020-09-23 00:00:00

abstract：:The basal ganglia, and the striatum in particular, have been implicated in the generation of contraversive movements. The striatum projects to downstream basal ganglia nuclei through two main circuits, originating in striatonigral and striatopallidal neurons, and different models postulate that the two pathways can wo...

journal_title：Nature communications

authors： Tecuapetla F,Matias S,Dugue GP,Mainen ZF,Costa RM

更新日期：2014-07-08 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is an autoimmune disease, characterised by increased expression of type I interferon (IFN)-regulated genes and a striking sex imbalance towards females. Through combined genetic, in silico, in vitro, and ex vivo approaches, we define CXorf21, a gene of hitherto unknown function, whic...

journal_title：Nature communications

authors： Odhams CA,Roberts AL,Vester SK,Duarte CST,Beales CT,Clarke AJ,Lindinger S,Daffern SJ,Zito A,Chen L,Jones LL,Boteva L,Morris DL,Small KS,Fernando MMA,Cunninghame Graham DS,Vyse TJ

更新日期：2019-05-15 00:00:00

abstract：:Nascent polypeptides can induce ribosome stalling, regulating downstream genes. Stalling of ErmBL peptide translation in the presence of the macrolide antibiotic erythromycin leads to resistance in Streptococcus sanguis. To reveal this stalling mechanism we obtained 3.6-Å-resolution cryo-EM structures of ErmBL-stalled...

journal_title：Nature communications

authors： Arenz S,Bock LV,Graf M,Innis CA,Beckmann R,Grubmüller H,Vaiana AC,Wilson DN

更新日期：2016-07-06 00:00:00

abstract：:We have developed a single-breath-hold photoacoustic computed tomography (SBH-PACT) system to reveal detailed angiographic structures in human breasts. SBH-PACT features a deep penetration depth (4 cm in vivo) with high spatial and temporal resolutions (255 µm in-plane resolution and a 10 Hz 2D frame rate). By scannin...

journal_title：Nature communications

authors： Lin L,Hu P,Shi J,Appleton CM,Maslov K,Li L,Zhang R,Wang LV

更新日期：2018-06-15 00:00:00

abstract：:The ciliary kinase NEK8 plays a critical role in situs determination and cystic kidney disease, yet its exact function remains unknown. In this study, we identify ANKS6 as a target and activator of NEK8. ANKS6 requires NEK8 for localizing to the ciliary inversin compartment (IC) and activates NEK8 by binding to its ki...

journal_title：Nature communications

authors： Czarnecki PG,Gabriel GC,Manning DK,Sergeev M,Lemke K,Klena NT,Liu X,Chen Y,Li Y,San Agustin JT,Garnaas MK,Francis RJ,Tobita K,Goessling W,Pazour GJ,Lo CW,Beier DR,Shah JV

更新日期：2015-01-20 00:00:00

abstract：:Coordinated activity of VEGF and Notch signals guides the endothelial cell (EC) specification into tip and stalk cells during angiogenesis. Notch activation in stalk cells leads to proliferation arrest via an unknown mechanism. By using gain- and loss-of-function gene-targeting approaches, here we show that PTEN is cr...

journal_title：Nature communications

authors： Serra H,Chivite I,Angulo-Urarte A,Soler A,Sutherland JD,Arruabarrena-Aristorena A,Ragab A,Lim R,Malumbres M,Fruttiger M,Potente M,Serrano M,Fabra À,Viñals F,Casanovas O,Pandolfi PP,Bigas A,Carracedo A,Gerhardt H,Gra

更新日期：2015-07-31 00:00:00

abstract：:Photovoltaic devices based on metal halide perovskites are rapidly improving in efficiency. Once the Shockley-Queisser limit is reached, charge-carrier extraction will be limited only by radiative bimolecular recombination of electrons with holes. Yet, this fundamental process, and its link with material stoichiometry...

journal_title：Nature communications

authors： Davies CL,Filip MR,Patel JB,Crothers TW,Verdi C,Wright AD,Milot RL,Giustino F,Johnston MB,Herz LM

更新日期：2018-01-18 00:00:00

abstract：:Cellular protein-RNA complexes assemble on nascent transcripts, but methods to observe transcription and protein binding in real time and at physiological concentrations are not available. Here, we report a single-molecule approach based on zero-mode waveguides that simultaneously tracks transcription progress and the...

journal_title：Nature communications

authors： Duss O,Stepanyuk GA,Grot A,O'Leary SE,Puglisi JD,Williamson JR

更新日期：2018-11-30 00:00:00