Clinical Validity of DSM-5 Attenuated Psychosis Syndrome: Advances in Diagnosis, Prognosis, and Treatment.

abstract：Importance:Suicide is a leading cause of deaths in the United States. Although the emergency department (ED) is an opportune setting for initiating suicide prevention efforts, ED-initiated suicide prevention interventions remain underdeveloped. Objective:To determine whether an ED-initiated intervention reduces subseq...

journal_title：JAMA psychiatry

authors： Miller IW,Camargo CA Jr,Arias SA,Sullivan AF,Allen MH,Goldstein AB,Manton AP,Espinola JA,Jones R,Hasegawa K,Boudreaux ED,ED-SAFE Investigators.

更新日期：2017-06-01 00:00:00

abstract：Importance:Although several strategies of repetitive transcranial magnetic stimulation (rTMS) have been investigated as treatment of major depressive disorder (MDD), their comparative efficacy and acceptability is unknown. Objective:To establish the relative efficacy and acceptability of the different modalities of rT...

journal_title：JAMA psychiatry

authors： Brunoni AR,Chaimani A,Moffa AH,Razza LB,Gattaz WF,Daskalakis ZJ,Carvalho AF

更新日期：2017-02-01 00:00:00

abstract：IMPORTANCE:Although high rates of current mental disorder are known to exist in the US Army, little is known about the proportions of these disorders that had onsets prior to enlistment. OBJECTIVE:To estimate the proportions of 30-day DSM-IV mental disorders among nondeployed US Army personnel with first onsets prior ...

journal_title：JAMA psychiatry

authors： Kessler RC,Heeringa SG,Stein MB,Colpe LJ,Fullerton CS,Hwang I,Naifeh JA,Nock MK,Petukhova M,Sampson NA,Schoenbaum M,Zaslavsky AM,Ursano RJ,Army STARRS Collaborators.

更新日期：2014-05-01 00:00:00

abstract：Importance:There is concern about potentially causal effects of tobacco use on psychosis, but epidemiological studies have been less robust in attempts to minimize effects of confounding than studies of cannabis use have been. Objectives:To examine the association of patterns of cigarette and cannabis use with precedi...

journal_title：JAMA psychiatry

authors： Jones HJ,Gage SH,Heron J,Hickman M,Lewis G,Munafò MR,Zammit S

更新日期：2018-03-01 00:00:00

abstract：Importance:Tobacco use disorder is associated with dysregulated neurocognitive function in the right inferior frontal gyrus (IFG)-one node in a corticothalamic inhibitory control (IC) network. Objective:To examine associations between IC neural circuitry structure and function and lapse/relapse vulnerability in 2 inde...

journal_title：JAMA psychiatry

authors： Froeliger B,McConnell PA,Bell S,Sweitzer M,Kozink RV,Eichberg C,Hallyburton M,Kaiser N,Gray KM,McClernon FJ

更新日期：2017-04-01 00:00:00

abstract：IMPORTANCE:Motivational and cognitive deficits are core features of schizophrenia, both closely linked with functional outcomes. Although poor effort and decreased motivation are known to affect performance on cognitive tests, the extent of this relationship is unclear in patients with schizophrenia. OBJECTIVE:To eval...

journal_title：JAMA psychiatry

authors： Fervaha G,Zakzanis KK,Foussias G,Graff-Guerrero A,Agid O,Remington G

更新日期：2014-09-01 00:00:00

abstract：Importance:A recent increase in patients presenting with nonfatal opioid overdoses has focused clinical attention on characterizing their risks of premature mortality. Objective:To describe all-cause mortality rates, selected cause-specific mortality rates, and standardized mortality rate ratios (SMRs) of adults durin...

journal_title：JAMA psychiatry

authors： Olfson M,Crystal S,Wall M,Wang S,Liu SM,Blanco C

更新日期：2018-08-01 00:00:00

abstract：IMPORTANCE:Posttraumatic stress disorder (PTSD) is a common, debilitating mental disorder that has been associated with type 2 diabetes mellitus (T2D) and its risk factors, including obesity, in cross-sectional studies. If PTSD increases risk of incident T2D, enhanced surveillance in high-risk populations may be warran...

journal_title：JAMA psychiatry

authors： Roberts AL,Agnew-Blais JC,Spiegelman D,Kubzansky LD,Mason SM,Galea S,Hu FB,Rich-Edwards JW,Koenen KC

更新日期：2015-03-01 00:00:00

abstract：IMPORTANCE:Cannabis dependence (CAD) is a serious problem worldwide and is of growing importance in the United States because cannabis is increasingly available legally. Although genetic factors contribute substantially to CAD risk, at present no well-established specific genetic risk factors for CAD have been elucidat...

journal_title：JAMA psychiatry

authors： Sherva R,Wang Q,Kranzler H,Zhao H,Koesterer R,Herman A,Farrer LA,Gelernter J

更新日期：2016-05-01 00:00:00

abstract：IMPORTANCE:Serotonin is involved in negative affect, but whether anxiety syndromes, such as social anxiety disorder (SAD), are characterized by an overactive or underactive serotonin system has not been established. Serotonin 1A autoreceptors, which inhibit serotonin synthesis and release, are downregulated in SAD, and...

journal_title：JAMA psychiatry

authors： Frick A,Åhs F,Engman J,Jonasson M,Alaie I,Björkstrand J,Frans Ö,Faria V,Linnman C,Appel L,Wahlstedt K,Lubberink M,Fredrikson M,Furmark T

更新日期：2015-08-01 00:00:00

abstract：IMPORTANCE:Forward models predict the sensory consequences of planned actions and permit discrimination of self- and non-self-elicited sensation; their impairment in schizophrenia is implied by an abnormality in behavioral force-matching and the flawed agency judgments characteristic of positive symptoms, including aud...

journal_title：JAMA psychiatry

authors： Shergill SS,White TP,Joyce DW,Bays PM,Wolpert DM,Frith CD

更新日期：2014-01-01 00:00:00

abstract：Importance:Little is known about changes in marijuana use and cannabis use disorder (CUD) after recreational marijuana legalization (RML). Objectives:To examine the associations between RML enactment and changes in marijuana use, frequent use, and CUD in the United States from 2008 to 2016. Design, Setting, and Parti...

journal_title：JAMA psychiatry

authors： Cerdá M,Mauro C,Hamilton A,Levy NS,Santaella-Tenorio J,Hasin D,Wall MM,Keyes KM,Martins SS

更新日期：2020-02-01 00:00:00

abstract：IMPORTANCE:After major policy changes in the United States, policymakers, health care professionals, and the general public seek information about whether recreational cannabis use is associated with physical health problems later in life. OBJECTIVE:To test associations between cannabis use over 20 years and a variety...

journal_title：JAMA psychiatry

authors： Meier MH,Caspi A,Cerdá M,Hancox RJ,Harrington H,Houts R,Poulton R,Ramrakha S,Thomson WM,Moffitt TE

更新日期：2016-07-01 00:00:00

abstract：Importance:Depressive severity is typically measured according to total scores on questionnaires that include a diverse range of symptoms despite convincing evidence that depression is not a unitary construct. When evaluated according to aggregate measurements, treatment efficacy is generally modest and differences in ...

journal_title：JAMA psychiatry

authors： Chekroud AM,Gueorguieva R,Krumholz HM,Trivedi MH,Krystal JH,McCarthy G

更新日期：2017-04-01 00:00:00

abstract：IMPORTANCE:In schizophrenia, working memory deficits appear to reflect abnormalities in the generation of gamma oscillations in the dorsolateral prefrontal cortex. The generation of gamma oscillations requires the phasic excitation of inhibitory parvalbumin-containing interneurons. Thus, gamma oscillations depend, in p...

journal_title：JAMA psychiatry

authors： Kimoto S,Zaki MM,Bazmi HH,Lewis DA

更新日期：2015-08-01 00:00:00

abstract：IMPORTANCE:Depression and obesity are 2 prevalent disorders that have been repeatedly shown to be associated. However, the mechanisms and temporal sequence underlying this association are poorly understood. OBJECTIVE:To determine whether the subtypes of major depressive disorder (MDD; melancholic, atypical, combined, ...

journal_title：JAMA psychiatry

authors： Lasserre AM,Glaus J,Vandeleur CL,Marques-Vidal P,Vaucher J,Bastardot F,Waeber G,Vollenweider P,Preisig M

更新日期：2014-08-01 00:00:00

abstract：Importance:Understanding the neurodevelopmental trajectory of psychiatric symptoms is important for improving early identification, intervention, and prevention of mental disorders. Objective:To test whether the strength of the coupling of activation between specific brain regions, as measured by resting-state functio...

journal_title：JAMA psychiatry

authors： Whitfield-Gabrieli S,Wendelken C,Nieto-Castañón A,Bailey SK,Anteraper SA,Lee YJ,Chai XQ,Hirshfeld-Becker DR,Biederman J,Cutting LE,Bunge SA

更新日期：2020-04-01 00:00:00

abstract：IMPORTANCE:National epidemiologic information from recently collected data on the new DSM-5 classification of alcohol use disorder (AUD) using a reliable, valid, and uniform data source is needed. OBJECTIVE:To present nationally representative findings on the prevalence, correlates, psychiatric comorbidity, associated...

journal_title：JAMA psychiatry

authors： Grant BF,Goldstein RB,Saha TD,Chou SP,Jung J,Zhang H,Pickering RP,Ruan WJ,Smith SM,Huang B,Hasin DS

更新日期：2015-08-01 00:00:00

abstract：IMPORTANCE:Major depressive disorder (MDD) is a heterogeneous condition in terms of symptoms, course, and underlying disease mechanisms. Current classifications do not adequately address this complexity. In novel network approaches to psychopathology, psychiatric disorders are conceptualized as complex dynamic systems ...

journal_title：JAMA psychiatry

authors： van Borkulo C,Boschloo L,Borsboom D,Penninx BW,Waldorp LJ,Schoevers RA

更新日期：2015-12-01 00:00:00

abstract：IMPORTANCE:The continuum view of the psychosis spectrum (PS) implies that, in population-based samples, PS symptoms should be associated with neural abnormalities similar to those found in help-seeking clinical risk individuals and in schizophrenia. To our knowledge, functional neuroimaging has not previously been appl...

journal_title：JAMA psychiatry

authors： Wolf DH,Satterthwaite TD,Calkins ME,Ruparel K,Elliott MA,Hopson RD,Jackson CT,Prabhakaran K,Bilker WB,Hakonarson H,Gur RC,Gur RE

更新日期：2015-05-01 00:00:00

abstract：IMPORTANCE:Psychosis-risk studies have examined help-seeking adolescents and young adults. Population-based studies evaluating psychotic symptoms and neurocognitive performance across childhood are needed for "growth charting" cognitive development. We hypothesized that psychosis spectrum youths have delayed neurocogni...

journal_title：JAMA psychiatry

authors： Gur RC,Calkins ME,Satterthwaite TD,Ruparel K,Bilker WB,Moore TM,Savitt AP,Hakonarson H,Gur RE

更新日期：2014-04-01 00:00:00

abstract：Importance:Suicide deaths are a leading cause of maternal mortality in the US, yet the prevalence and trends in suicidality (suicidal ideation and/or intentional self-harm) among childbearing individuals remain poorly described. Objective:To characterize trends in suicidality among childbearing individuals. Design, S...

journal_title：JAMA psychiatry

authors： Admon LK,Dalton VK,Kolenic GE,Ettner SL,Tilea A,Haffajee RL,Brownlee RM,Zochowski MK,Tabb KM,Muzik M,Zivin K

更新日期：2020-11-18 00:00:00

abstract：Importance:Identifying genes and proteins for cognitive resilience (ie, targets that may be associated with slowing or preventing cognitive decline regardless of the presence, number, or combination of common neuropathologic conditions) provides a complementary approach to developing novel therapeutics for the treatmen...

journal_title：JAMA psychiatry

authors： Yu L,Tasaki S,Schneider JA,Arfanakis K,Duong DM,Wingo AP,Wingo TS,Kearns N,Thatcher GRJ,Seyfried NT,Levey AI,De Jager PL,Bennett DA

更新日期：2020-07-01 00:00:00

abstract：Importance:There has been limited systematic examination of whether risk of suicide attempt (SA) among US Army soldiers is associated with time-related deployment variables, such as time in service before first deployment, duration of first deployment, and dwell time (DT) (ie, length of time between deployments). Obje...

journal_title：JAMA psychiatry

authors： Ursano RJ,Kessler RC,Naifeh JA,Herberman Mash H,Fullerton CS,Aliaga PA,Wynn GH,Ng THH,Dinh HM,Sampson NA,Kao TC,Bliese PD,Stein MB

更新日期：2018-06-01 00:00:00

abstract：Importance:Growing evidence suggests that prescription opioid use affects depression and anxiety disorders; however, observational studies are subject to confounding, making causal inference and determining the direction of these associations difficult. Objective:To investigate the potential bidirectional associations...

journal_title：JAMA psychiatry

authors： Rosoff DB,Smith GD,Lohoff FW

更新日期：2020-11-11 00:00:00

abstract：:CONTEXT Suicide bereavement remains understudied and poorly understood. OBJECTIVES To examine outcomes of parents bereaved by the suicide death of their offspring and to compare these with both nonbereaved parent controls and parents who had offspring die in a motor vehicle crash (MVC). DESIGN Population-based case-co...

journal_title：JAMA psychiatry

authors： Bolton JM,Au W,Leslie WD,Martens PJ,Enns MW,Roos LL,Katz LY,Wilcox HC,Erlangsen A,Chateau D,Walld R,Spiwak R,Seguin M,Shear K,Sareen J

更新日期：2013-02-01 00:00:00

abstract：IMPORTANCE:Compulsory admissions, defined as admissions against the will of the patient (according to local judicial procedures), have a strong effect on psychiatric patients. In several Western countries, the rate of such admissions is tending to rise. Its reduction is urgently needed. OBJECTIVE:To establish which in...

journal_title：JAMA psychiatry

authors： de Jong MH,Kamperman AM,Oorschot M,Priebe S,Bramer W,van de Sande R,Van Gool AR,Mulder CL

更新日期：2016-07-01 00:00:00

abstract：Importance:Suicide is a public health problem, with multiple causes that are poorly understood. The increased focus on combining health care data with machine-learning approaches in psychiatry may help advance the understanding of suicide risk. Objective:To examine sex-specific risk profiles for death from suicide usi...

journal_title：JAMA psychiatry

authors： Gradus JL,Rosellini AJ,Horváth-Puhó E,Street AE,Galatzer-Levy I,Jiang T,Lash TL,Sørensen HT

更新日期：2020-01-01 00:00:00

abstract：IMPORTANCE:At least 11 rare copy number variants (CNVs) have been shown to be major risk factors for schizophrenia (SZ). These CNVs also increase the risk for other neurodevelopmental disorders, such as intellectual disability. It is possible that additional intellectual disability-associated CNVs increase the risk for...

journal_title：JAMA psychiatry

authors： Rees E,Kendall K,Pardiñas AF,Legge SE,Pocklington A,Escott-Price V,MacCabe JH,Collier DA,Holmans P,O'Donovan MC,Owen MJ,Walters JTR,Kirov G

更新日期：2016-09-01 00:00:00

abstract：IMPORTANCE:Adverse childhood experiences (ACEs) are associated with several adulthood health problems, such as self-directed violence. For some individuals, enlistment in the military may be an instrumental act to escape adverse household environments; however, to our knowledge prevalence of ACEs among persons with a h...

journal_title：JAMA psychiatry

authors： Blosnich JR,Dichter ME,Cerulli C,Batten SV,Bossarte RM

更新日期：2014-09-01 00:00:00