HIV Preexposure Prophylaxis-The Role of Primary Care Clinicians in Ending the HIV Epidemic.

abstract：IMPORTANCE:Better continuity of care is expected to improve patient outcomes and reduce health care costs, but patterns of use, costs, and clinical complications associated with the current patterns of care continuity have not been quantified. OBJECTIVE:To measure the association between care continuity, costs, and ra...

journal_title：JAMA internal medicine

authors： Hussey PS,Schneider EC,Rudin RS,Fox DS,Lai J,Pollack CE

更新日期：2014-05-01 00:00:00

abstract：Importance:Lung cancer has become a leading cause of death among people living with human immunodeficiency virus (HIV) (PLWH). Over 40% of PLWH in the United States smoke cigarettes; HIV independently increases the risk of lung cancer. Objective:To project cumulative lung cancer mortality by smoking exposure among PLW...

journal_title：JAMA internal medicine

authors： Reddy KP,Kong CY,Hyle EP,Baggett TP,Huang M,Parker RA,Paltiel AD,Losina E,Weinstein MC,Freedberg KA,Walensky RP

更新日期：2017-11-01 00:00:00

abstract：IMPORTANCE:For antidepressants, the translation of evidence of comparative effectiveness into practice is suboptimal. This deficit directly affects outcomes and quality of care for patients with depression. To overcome this problem, we developed the Depression Medication Choice (DMC) encounter decision aid, designed to...

journal_title：JAMA internal medicine

authors： LeBlanc A,Herrin J,Williams MD,Inselman JW,Branda ME,Shah ND,Heim EM,Dick SR,Linzer M,Boehm DH,Dall-Winther KM,Matthews MR,Yost KJ,Shepel KK,Montori VM

更新日期：2015-11-01 00:00:00

abstract：Importance:Previous studies identify gestational diabetes (GD) as a risk factor for intermediate markers of cardiovascular disease (CVD) risk; however, few are prospective, evaluate hard CVD end points, or account for shared risk factors including body weight and lifestyle. Objective:To prospectively evaluate history ...

journal_title：JAMA internal medicine

authors： Tobias DK,Stuart JJ,Li S,Chavarro J,Rimm EB,Rich-Edwards J,Hu FB,Manson JE,Zhang C

更新日期：2017-12-01 00:00:00

abstract：Importance:The effects of acupuncture as adjunctive treatment to antianginal therapies for patients with chronic stable angina are uncertain. Objective:To investigate the efficacy and safety of acupuncture as adjunctive therapy to antianginal therapies in reducing frequency of angina attacks in patients with chronic s...

journal_title：JAMA internal medicine

authors： Zhao L,Li D,Zheng H,Chang X,Cui J,Wang R,Shi J,Fan H,Li Y,Sun X,Zhang F,Wu X,Liang F

更新日期：2019-07-29 00:00:00

abstract：IMPORTANCE:The effect of strict blood pressure control on clinical outcomes in patients with chronic kidney disease (CKD) is unclear. OBJECTIVE:To compare the outcomes associated with a treated systolic blood pressure (SBP) of less than 120 mm Hg vs those associated with the currently recommended SBP of less than 140 ...

journal_title：JAMA internal medicine

authors： Kovesdy CP,Lu JL,Molnar MZ,Ma JZ,Canada RB,Streja E,Kalantar-Zadeh K,Bleyer AJ

更新日期：2014-09-01 00:00:00

abstract：Importance:Approximately 1 million patients in the United States with type 2 diabetes mellitus and mild-to-moderate kidney disease do not receive guideline-directed therapy with metformin. This may reflect uncertainty regarding the risk of acidosis in patients with chronic kidney disease. Objective:To quantify the ass...

journal_title：JAMA internal medicine

authors： Lazarus B,Wu A,Shin JI,Sang Y,Alexander GC,Secora A,Inker LA,Coresh J,Chang AR,Grams ME

更新日期：2018-07-01 00:00:00

abstract：Importance:Elevated incidence rates of thyroid cancer among World Trade Center (WTC)-exposed individuals may be associated with the identification of asymptomatic cancers during medical surveillance. Objective:To examine the association between WTC exposure and thyroid cancer among Fire Department of the City of New Y...

journal_title：JAMA internal medicine

authors： Colbeth HL,Genere N,Hall CB,Jaber N,Brito JP,El Kawkgi OM,Goldfarb DG,Webber MP,Schwartz TM,Prezant DJ,Zeig-Owens R

更新日期：2020-06-01 00:00:00

abstract：Importance:Low-value care is prevalent in the United States, yet little is known about the downstream health care use triggered by low-value services. Measurement of such care cascades is essential to understanding the full consequences of low-value care. Objective:To describe cascades (tests, treatments, visits, hosp...

journal_title：JAMA internal medicine

authors： Ganguli I,Lupo C,Mainor AJ,Raymond S,Wang Q,Orav EJ,Chang CH,Morden NE,Rosenthal MB,Colla CH,Sequist TD

更新日期：2019-06-03 00:00:00

abstract：IMPORTANCE:The 2008 Physical Activity Guidelines for Americans recommended a minimum of 75 vigorous-intensity or 150 moderate-intensity minutes per week (7.5 metabolic-equivalent hours per week) of aerobic activity for substantial health benefit and suggested additional benefits by doing more than double this amount. H...

journal_title：JAMA internal medicine

authors： Arem H,Moore SC,Patel A,Hartge P,Berrington de Gonzalez A,Visvanathan K,Campbell PT,Freedman M,Weiderpass E,Adami HO,Linet MS,Lee IM,Matthews CE

更新日期：2015-06-01 00:00:00

abstract：Importance:Chronic kidney disease (CKD) is common in adults with heart failure and is associated with an increased risk of sudden cardiac death. Randomized trials of participants without CKD have demonstrated that implantable cardioverter defibrillators (ICDs) decrease the risk of arrhythmic death in selected patients ...

journal_title：JAMA internal medicine

authors： Bansal N,Szpiro A,Reynolds K,Smith DH,Magid DJ,Gurwitz JH,Masoudi F,Greenlee RT,Tabada GH,Sung SH,Dighe A,Go AS

更新日期：2018-03-01 00:00:00

abstract：Importance:Initiatives to reduce sodium in packaged foods have been launched in the United States, yet corresponding changes in the amount of sodium that US households obtain from packaged foods have not been evaluated, to our knowledge. Objective:To assess 15-year changes in the amount of sodium that US households ac...

journal_title：JAMA internal medicine

authors： Poti JM,Dunford EK,Popkin BM

更新日期：2017-07-01 00:00:00

abstract：Importance:Radiation doses for computed tomography (CT) vary substantially across institutions. Objective:To assess the impact of institutional-level audit and collaborative efforts to share best practices on CT radiation doses across 5 University of California (UC) medical centers. Design, Setting, and Participants:...

journal_title：JAMA internal medicine

authors： Demb J,Chu P,Nelson T,Hall D,Seibert A,Lamba R,Boone J,Krishnam M,Cagnon C,Bostani M,Gould R,Miglioretti D,Smith-Bindman R

更新日期：2017-06-01 00:00:00

abstract：IMPORTANCE:In type 2 diabetes mellitus (T2DM), team management using protocols with regular feedback improves clinical outcomes, although suboptimal self-management and psychological distress remain significant challenges. OBJECTIVE:To investigate if frequent contacts through a telephone-based peer support program (Pe...

journal_title：JAMA internal medicine

authors： Chan JC,Sui Y,Oldenburg B,Zhang Y,Chung HH,Goggins W,Au S,Brown N,Ozaki R,Wong RY,Ko GT,Fisher E,JADE and PEARL Project Team.

更新日期：2014-06-01 00:00:00

abstract：Importance:Staphylococcus aureus bacteremia is common and frequently associated with poor outcomes. Evidence indicates that specific care processes are associated with improved outcomes for patients with S aureus bacteremia, including appropriate antibiotic prescribing, use of echocardiography to identify endocarditis,...

journal_title：JAMA internal medicine

authors： Goto M,Schweizer ML,Vaughan-Sarrazin MS,Perencevich EN,Livorsi DJ,Diekema DJ,Richardson KK,Beck BF,Alexander B,Ohl ME

更新日期：2017-10-01 00:00:00

abstract：IMPORTANCE:Experts debate optimal 25-hydroxyvitamin D (25[OH]D) levels for musculoskeletal health. OBJECTIVE:To compare the effects of placebo, low-dose cholecalciferol, and high-dose cholecalciferol on 1-year changes in total fractional calcium absorption, bone mineral density, Timed Up and Go and five sit-to-stand t...

journal_title：JAMA internal medicine

authors： Hansen KE,Johnson RE,Chambers KR,Johnson MG,Lemon CC,Vo TN,Marvdashti S

更新日期：2015-10-01 00:00:00

abstract：IMPORTANCE:Up-front treatment of older men with low-risk prostate cancer can cause morbidity without clear survival benefit; however, most such patients receive treatment instead of observation. The impact of physicians on the management approach is uncertain. OBJECTIVE:To determine the impact of physicians on the man...

journal_title：JAMA internal medicine

authors： Hoffman KE,Niu J,Shen Y,Jiang J,Davis JW,Kim J,Kuban DA,Perkins GH,Shah JB,Smith GL,Volk RJ,Buchholz TA,Giordano SH,Smith BD

更新日期：2014-09-01 00:00:00

abstract：IMPORTANCE:Healthcare overuse, the delivery of low-value services, is increasingly recognized as a critical problem. However, little is known about the comparative effectiveness of alternate formats for presenting benefits and harms information to patients as a strategy to reduce overuse. OBJECTIVE:To examine the effe...

journal_title：JAMA internal medicine

authors： Sheridan SL,Sutkowi-Hemstreet A,Barclay C,Brewer NT,Dolor RJ,Gizlice Z,Lewis CL,Reuland DS,Golin CE,Kistler CE,Vu M,Harris R

更新日期：2016-01-01 00:00:00

abstract：IMPORTANCE:Pulmonary nodules are common, and more will be found with implementation of lung cancer screening. How potentially malignant pulmonary nodules are evaluated may affect patient outcomes, health care costs, and effectiveness of lung cancer screening programs. Guidelines for evaluating pulmonary nodules for can...

journal_title：JAMA internal medicine

authors： Wiener RS,Gould MK,Slatore CG,Fincke BG,Schwartz LM,Woloshin S

更新日期：2014-06-01 00:00:00

abstract：IMPORTANCE:Transthoracic echocardiography (TTE) accounts for almost half of all cardiac imaging services and is a widely available and versatile tool. Appropriate use criteria (AUC) for echocardiography were developed to improve patient care and health outcomes. Prior studies have shown that most TTEs are appropriate b...

journal_title：JAMA internal medicine

authors： Matulevicius SA,Rohatgi A,Das SR,Price AL,DeLuna A,Reimold SC

更新日期：2013-09-23 00:00:00

abstract：Importance:Maximizing the value of critical care services requires understanding the relationship between intensive care unit (ICU) utilization, clinical outcomes, and costs. Objective:To examine whether hospitals had consistent patterns of ICU utilization across 4 common medical conditions and the association between...

journal_title：JAMA internal medicine

authors： Chang DW,Shapiro MF

更新日期：2016-10-01 00:00:00

abstract：Importance:The safety of discharging adult patients recovering from critical illness directly home from the intensive care unit (ICU) is unknown. Objective:To compare the health care utilization and clinical outcomes for ICU patients discharged directly home from the ICU with those of patients discharged home via the ...

journal_title：JAMA internal medicine

authors： Stelfox HT,Soo A,Niven DJ,Fiest KM,Wunsch H,Rowan KM,Bagshaw SM

更新日期：2018-10-01 00:00:00

abstract：IMPORTANCE:Chronic obstructive pulmonary disease (COPD) is a common and deadly disease. Long-acting inhaled β-agonists and anticholinergics, first-line medications for COPD, have been associated with increased risk of cardiovascular outcomes. When choosing between the medications, patients and physicians would benefit ...

journal_title：JAMA internal medicine

authors： Gershon A,Croxford R,Calzavara A,To T,Stanbrook MB,Upshur R,Stukel TA

更新日期：2013-07-08 00:00:00

abstract：IMPORTANCE:Persons with type 2 diabetes mellitus (T2DM) are at increased risk for decline in cognitive function, reduced brain volume, and increased white matter lesions in the brain. Poor control of blood pressure (BP) and lipid levels are risk factors for T2DM-related cognitive decline, but the effect of intensive tr...

journal_title：JAMA internal medicine

authors： Williamson JD,Launer LJ,Bryan RN,Coker LH,Lazar RM,Gerstein HC,Murray AM,Sullivan MD,Horowitz KR,Ding J,Marcovina S,Lovato L,Lovato J,Margolis KL,Davatzikos C,Barzilay J,Ginsberg HN,Linz PE,Miller ME,Action to Contr

更新日期：2014-03-01 00:00:00

abstract：Importance:As cervical cancer screening transitions from Papanicolaou cytologic screening to primary human papillomavirus (HPV) testing worldwide, effective triage tests are needed to decide who among the HPV-positive women should receive further diagnostic evaluation to avoid unnecessary colposcopies and biopsies. Ob...

journal_title：JAMA internal medicine

authors： Wentzensen N,Clarke MA,Bremer R,Poitras N,Tokugawa D,Goldhoff PE,Castle PE,Schiffman M,Kingery JD,Grewal KK,Locke A,Kinney W,Lorey TS

更新日期：2019-07-01 00:00:00

abstract：Importance:Chlorthalidone is currently recommended as the preferred thiazide diuretic to treat hypertension, but no trials have directly compared risks and benefits. Objective:To compare the effectiveness and safety of chlorthalidone and hydrochlorothiazide as first-line therapies for hypertension in real-world practi...

journal_title：JAMA internal medicine

authors： Hripcsak G,Suchard MA,Shea S,Chen R,You SC,Pratt N,Madigan D,Krumholz HM,Ryan PB,Schuemie MJ

更新日期：2020-04-01 00:00:00

abstract：Importance:End-of-life care is costly, and decedents often experience overtreatment or low-quality care. Noninvasive ventilation (NIV) may be a palliative approach to avoid invasive mechanical ventilation (IMV) among select patients who are hospitalized at the end of life. Objective:To examine the trends in NIV and IM...

journal_title：JAMA internal medicine

authors： Sullivan DR,Kim H,Gozalo PL,Bunker J,Teno JM

更新日期：2021-01-01 00:00:00

abstract：IMPORTANCE:Antihypertensive agents are the most commonly prescribed class of medications in the United States. Evidence regarding the relationship between different types of antihypertensives and breast cancer risk is sparse and inconsistent, and prior studies have lacked the capacity to assess impacts of long-term use...

journal_title：JAMA internal medicine

authors： Li CI,Daling JR,Tang MT,Haugen KL,Porter PL,Malone KE

更新日期：2013-09-23 00:00:00

abstract：Importance:Clinician communication about goals of care is associated with improved patient outcomes and reduced intensity of end-of-life care, but it is unclear whether interventions can improve this communication. Objective:To evaluate the efficacy of a patient-specific preconversation communication-priming intervent...

journal_title：JAMA internal medicine

authors： Curtis JR,Downey L,Back AL,Nielsen EL,Paul S,Lahdya AZ,Treece PD,Armstrong P,Peck R,Engelberg RA

更新日期：2018-07-01 00:00:00

abstract：IMPORTANCE:Additional information is needed about the role of dietary sodium on health outcomes in older adults. OBJECTIVE:To examine the association between dietary sodium intake and mortality, incident cardiovascular disease (CVD), and incident heart failure (HF) in older adults. DESIGN, SETTING, AND PARTICIPANTS:W...

journal_title：JAMA internal medicine

authors： Kalogeropoulos AP,Georgiopoulou VV,Murphy RA,Newman AB,Bauer DC,Harris TB,Yang Z,Applegate WB,Kritchevsky SB

更新日期：2015-03-01 00:00:00