Abstract:
PURPOSE:Urethroplasty is the most effective treatment method for anterior urethral strictures, which constitute an important health concern for males. This study aims to investigate factors that may predict treatment failure following urethroplasty for anterior urethral strictures and evaluate outcomes of different urethroplasty techniques. METHODS:This retrospective study utilized univariate and multivariate analyses to identify factors affecting treatment success following different urethroplasty techniques performed by a single surgeon on male patients with anterior urethral strictures. Surgical outcomes of different urethroplasty techniques were evaluated individually. RESULTS:Urethroplasty procedures performed on 244 patients with a mean age of 54 years and a mean stricture length of 4.7 cm produced a success rate of 79.1%. Multivariate analyses identified stricture length and number of previous internal urethrotomy procedures as factors predicting urethroplasty success (HR 1.265, 95% CI 1.129-1.416, p < 0.001 and HR 1.188, 95% CI 1.038-1.361, p = 0.013, respectively). The eight surgical techniques used by the surgeon produced success rates that varied between 50% and 86.2%. CONCLUSION:Urethroplasty can offer satisfactory outcomes for anterior urethral strictures. Accordingly, a longer stricture length and greater number of previous internal urethrotomy procedures were associated with greater risk for urethroplasty failure. Moreover, urethroplasty techniques must be selected based on multifactorial evaluation and performed at experienced centers.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Yalçınkaya F,Kartal Idoi
10.1007/s00345-019-03014-zsubject
Has Abstractpub_date
2020-09-01 00:00:00pages
2313-2319issue
9eissn
0724-4983issn
1433-8726pii
10.1007/s00345-019-03014-zjournal_volume
38pub_type
杂志文章abstract:OBJECTIVES:Adjuvant chemotherapy (ACT) is recommended for non-organ-confined bladder cancer (BCa) after radical cystectomy (RC) and pelvic lymph node dissection (PLND), but there are sparse data regarding its specific efficacy in patients with histological variants. The aim of our study was to evaluate the role of ACT ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03362-1
更新日期:2020-07-25 00:00:00
abstract:PURPOSE:MicroRNAs (miRNAs) play an important role as regulators of gene expression in tumourigenesis by controlling many biological processes in growth, development, differentiation and apoptosis. Previous studies have shown an altered expression of specific miRNAs in clear cell renal cell carcinoma (ccRCC). But the fu...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-010-0633-4
更新日期:2011-06-01 00:00:00
abstract::Familial risks for cancer are important for clinical counseling and understanding cancer etiology. The nationwide Swedish Family-Cancer Database includes all Swedes born in 1932 and later (0 to 68-year-old offspring) with their parents, totaling over 10.2 million individuals. Urological cancer cases were retrieved fro...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-003-0375-7
更新日期:2004-02-01 00:00:00
abstract::Can urolithiasis start as an intratubular event? Under severe hyperoxaluric conditions in animal models at least crystal formation can. Recently models have been presented that assess the chances of crystal formation under more normal conditions. These models describe changes in fluid composition as this passes throug...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/BF01367659
更新日期:1997-01-01 00:00:00
abstract:PURPOSE:To examine phosphodiesterase type 5 (PDE5) expression in the anterior fibromuscular stroma (AFMS) of the prostate. Although PDE5 expression was identified in the human prostate, differences in PDE5 expression in intra-prostatic regions are unknown. The AFMS in the prostate has peculiar innervations that could c...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03095-1
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:Patients and their families utilize online resources when dealing with a diagnosis of bladder cancer. Many patients have questions regarding clinical management options. Online research forums may help researchers and providers identify research areas of interest. Our objective was to review online forums and i...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2479-0
更新日期:2019-06-01 00:00:00
abstract::We are fortunate that our ability to diagnose the specific adrenal entities that mandate a surgical approach is extremely accurate. The combination of analytical methodology to measure the appropriate adrenocortical and medullary hormone production and the radiology techniques for localization are superb. The manageme...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s003450050103
更新日期:1999-02-01 00:00:00
abstract:PURPOSE:To describe results of a simplified technique to configure the vesicourethral anastomosis and to restore posterior musculofascial plate during laparoscopic radical prostatectomy with a "single knot-single running" suture. METHODS:Between December 2006 and 2009, a conventional Van Velthoven anastomosis (group A...
journal_title:World journal of urology
pub_type: 临床试验,杂志文章
doi:10.1007/s00345-012-0840-2
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To assess the performance of EAU risk classification in PCa patients according to the biopsy pathway (standard versus MRI guided) and to develop a new, more accurate, targeted biopsy (TB)-based classification. MATERIALS AND METHODS:We included 1345 patients consecutively operated by radical prostatectomy (RP) ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-03053-6
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:To analyse whether the reported differences in nodal yield at pelvic lymph node dissection (PLND) for bladder cancer, between two hospitals, are reflected in the survival rates. PATIENTS AND METHODS:We assessed follow-up data of all 174 patients (mean age: 62.7, median follow-up: 3 years) who underwent PLND ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-012-0916-z
更新日期:2013-10-01 00:00:00
abstract::The diagnosis of prostate cancer (PCa) can be challenging due to the limited performance of current diagnostic tests, including PSA, digital rectal examination and transrectal conventional US. Multiparametric MRI has improved PCa diagnosis and is recommended prior to biopsy; however, mp-MRI does miss a substantial num...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03193-0
更新日期:2020-04-18 00:00:00
abstract:OBJECTIVES:Monopolar transurethral resection of the prostate (TURP) is the gold standard surgical treatment for bothersome moderate to severe lower urinary tract symptoms (LUTS) secondary to benign prostate obstruction. The aim of the study is to compare monopolar versus bipolar TURP focusing on operative and functiona...
journal_title:World journal of urology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00345-017-2023-7
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:Prostate Imaging Reporting and Data System version 2 (PI-RADSv2) provides reasonable performance in detecting significant cancers. Still, it is unclear about whether all PI-RADS 4 lesions show the same cancer detection rate (CDR) regardless of tumor size. The aim was to compare the CDRs of small (< 10 mm) and l...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02924-2
更新日期:2020-06-01 00:00:00
abstract::Local recurrent prostate cancer after radical treatment is found in the majority of men with a rising PSA. Salvage treatment procedures for recurrent disease, such as radiation therapy and ablative procedures, can provide long-term responses in well-selected cases. Prostate magnetic resonance imaging (MRI) allows diag...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-019-02677-y
更新日期:2019-08-01 00:00:00
abstract::A basic understanding of the mediators and related mechanisms involved in the genital physiology of the female sexual response, and, in particular, the physiology of arousal, is paramount for the clinical practitioner whose medical knowledge and practice pertain to female sexual dysfunction. Familiarity with establish...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-002-0271-6
更新日期:2002-06-01 00:00:00
abstract:PURPOSE:Previous studies examining the management of urinary tract infections (UTI) showed marked variability in the economical burden of care, with a tenfold increase in costs when patients require admission to the hospital. We sought to examine the patient and emergency department (ED) characteristics associated with...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-013-1167-3
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:To report survival outcomes of patients treated surgically for sarcomatoid-variant renal cell carcinomas (sRCC) and to assess whether the underlying histologic subtype is an independent predictor of outcome. METHODS:One hundred and fifty-one patients underwent surgery at a referral center between 1991 and 2014...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1644-y
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:To investigate pathological and oncological outcomes of obese patients who underwent robot-assisted radical prostatectomy (RARP) compared with laparoscopic radical prostatectomy (LRP) or open retropubic radical prostatectomy (RRP) since limited comparative data exist with regard to oncological and survival o...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-014-1326-1
更新日期:2015-03-01 00:00:00
abstract:INTRODUCTION:Erectile dysfunction (ED) and cardiovascular disease (CVD) share a great number of common risk factors. There is growing evidence that aldosterone, an independent CVD risk factor, is associated with ED. AIMS:The purpose of this study was to determine the relationship between plasma aldosterone and erectil...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1723-0
更新日期:2016-07-01 00:00:00
abstract::Recent investigations have given a clearer insight into the genetic progression of bladder cancer. In this review we identify the clinical courses of bladder cancer, review the basic concepts of carcinogenesis, and focus on the specific cytogenetic and molecular alterations observed in bladder cancer. Progression mode...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/BF00184243
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:Reactive oxygen species (ROS) are produced during the interaction between oxalate/calcium oxalate monohydrate (COM) crystals and renal epithelial cells and are responsible for the various cellular responses through the activation of NADPH oxidase (Nox). Ox and COM also activate the renin-ang...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1563-y
更新日期:2016-01-01 00:00:00
abstract::The effects of pelvic floor muscle contraction on rectal and vesical function were studied in 19 healthy volunteers with the aim of shedding light on some of the hitherto vague aspects of the mechanisms involved in micturition and defecation and their disorders. Rectal and vesical pressures were recorded during pubore...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s003450100218
更新日期:2001-08-01 00:00:00
abstract:PURPOSE:Current systemic treatment of targeted therapies, namely the vascular endothelial growth factor-antibody (VEGF-AB), VEGF receptor tyrosine kinase inhibitor (TKI) and mammalian target of rapamycin (mTOR) inhibitors, have improved progression-free survival and replaced non-specific immunotherapy with cytokines in...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-016-1868-5
更新日期:2017-02-01 00:00:00
abstract::Ileal conduits have long been accepted as a standard method for urinary diversion, but conventional ileal conduits are not always suitable for patients whose ureters are for the greater part compromised by neoplasm or preoperative irradiation, resulting in a shortening of the ureters. Bowel migration into the large ca...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s003450050092
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:We aim to evaluate prostate-specific antigen (PSA) trends in post-primary focal cryotherapy (PFC) patients. MATERIALS AND METHODS:This was an institutional review board-approved retrospective study of PFC patients from 2010 to 2015. Patients with at least one post-PFC PSA were included in the study. Biochemica...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-017-2130-5
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:To investigate the spontaneous clearance rates of remnant particles following miniaturized percutaneous nephrolithotomy (mini-PCNL) and retrograde intrarenal surgery (RIRS). METHODS:Among 624 patients who underwent mini-PCNL or RIRS at our institution from 2011 to 2015, we collected data of 247 patients with 2...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-016-1807-5
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:Testicular torsion is the most concerning underlying cause of acute scrotal pain that can lead to loss of the affected testicle. Whether a torted testicle can be salvaged surgically is directly affected by prompt presentation and diagnosis. This study aims to evaluate the awareness of testicular torsion amongst...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2269-8
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:To examine patterns of crowdsourcing on the social media platform Twitter among urologists. METHODS:Urologists' public Twitter accounts were reviewed for original posts seeking clinical advice or feedback, and associated reply posts, before and after the 140-character-limit expansion in 2017. Predictors of res...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2405-5
更新日期:2019-03-01 00:00:00
abstract:PURPOSE:Salvage radiotherapy (SRT) for biochemical recurrence (BCR) following radical prostatectomy (RP) should if possible be added at a prostate-specific antigen (PSA) level of <1-2 ng/mL. The value of positron emission tomography combined with computed tomography (PET/CT) at such low PSA values is not defined. The p...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1547-y
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:To assess treatments and survival of patients with muscle invasive bladder cancer (MIBC) in the Comprehensive Cancer Center Northern Netherlands (CCCN) region. STUDY DESIGN AND SETTING:Retrospective cohort analysis. Data of 548 patients with MIBC diagnosed between 1997 and 2002 were collected from the CCCN c...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-010-0546-2
更新日期:2010-08-01 00:00:00