Effect of Different Doses of Inhaled Corticosteroids on the Isolation of Nasopharyngeal Flora in Children with Asthma.

Abstract:

OBJECTIVE:To find the effects of inhaled corticosteroids and the impact of different doses of inhaled corticosteroids on the isolation of nasopharyngeal flora in asthmatic children aged 1-15 years. METHODS:The study included 75 children with asthma and 25 age-matched controls. Nasopharyngeal swabs were obtained. Bacteria were identified by standard techniques. RESULTS:Pathogenic organisms were isolated from 36% of asthmatic children and 20% of controls, the difference was not significant statistically (OR=2.25, 95% CI=0.75-6.67, P=0.13). There was no statistically significant association of using a high dose of inhaled corticosteroids with the isolation of pathogenic organisms. Usage of biomass fuel for cooking in the household of asthmatic children increases the risk of colonization (OR=3.4, 95% CI= 1.26-9.10, P=0.03). CONCLUSIONS:Inhaled corticosteroids are safe in the treatment of asthma and there is no association between different doses of Inhaled corticosteroids and isolation of the pathogenic organism.

journal_name

Indian Pediatr

journal_title

Indian pediatrics

authors

Nirmal G,Awasthi S,Gupta S,Aggarwal J

subject

Has Abstract

pub_date

2019-11-15 00:00:00

pages

913-916

issue

11

eissn

0019-6061

issn

0974-7559

journal_volume

56

pub_type

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