Treatment Strategy for Distant Synchronous Metastatic Head and Neck Squamous Cell Carcinoma.

abstract：:High-risk non-melanoma skin cancer (NMSC) of the head and neck is difficult to manage, given its propensity for regional metastasis, perineural invasion, direct parotid invasion, and bony destruction. Management of these tumors demands awareness of the characteristics contributing to their recurrence. Recent studies e...

journal_title：Current oncology reports

authors： Lai SY,Weber RS

更新日期：2005-03-01 00:00:00

abstract：:Neuroblastoma is the most common extracranial tumor of childhood, with about 650 new cases each year in the United States. The clinical course of neuroblastoma is variable and depends on age at diagnosis, staging, histology, and specific genetic abnormalities, such as MYCN oncogene amplification or aberrations of chro...

journal_title：Current oncology reports

authors： Mueller S,Matthay KK

更新日期：2009-11-01 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is the leading cause of death from cancer worldwide and has a poor overall survival across all stages of disease. The recent advancement of gene expression technology addresses the phenotypic complexity of many diseases, including NSCLC. These genomic approaches have shown great prom...

journal_title：Current oncology reports

authors： Jolly Graham A,Potti A

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The American Society of Clinical Oncology (ASCO) palliative care recommendations have been updated into a full guideline. Symptom questionnaires-completed and reviewed with patients during care delivery-are poised to play a large role in this guideline because they provide a more comprehensive underst...

journal_title：Current oncology reports

authors： Stover AM,Basch EM

更新日期：2017-02-01 00:00:00

abstract：:Cancer risk has become a significant research topic due to an increase in statistical risk models built to predict cancer incidence or mortality. Over the past 3 years, 15 models on the development of different types of cancer, including breast, colorectal, prostate, gastric, lung, ovarian, pancreatic, testicular, and...

journal_title：Current oncology reports

authors： Johnson CM,Smolenski D

更新日期：2007-11-01 00:00:00

abstract：:Many women undergo mastectomy as treatment of their breast cancer either because of personal preference or because of tumor-related factors making mastectomy the preferred surgical option. The use of postmastectomy radiation therapy has been shown to decrease the risk of local recurrence and in some cases improve over...

journal_title：Current oncology reports

authors： Lyons JA,Sherertz T

更新日期：2014-01-01 00:00:00

abstract：:Hypogonadism is common throughout the illness trajectory of patients with cancer. About two thirds of male patients with advanced cancer have hypothalamic-pituitary-gonadal dysfunction and low testosterone levels. Chronic inflammation, comorbidities, cachexia, chemotherapy, and medications such as opioids, megestrol a...

journal_title：Current oncology reports

authors： Dev R,Bruera E,Del Fabbro E

更新日期：2014-04-01 00:00:00

abstract：:Epidemiologic studies supported by molecular technology have provided sufficient evidence of the causal role of some human papillomavirus (HPV) infections in the development of cervical cancer. The finding is consistent universally, and HPV has been proposed as the first identified necessary cause of cervical cancer. ...

journal_title：Current oncology reports

authors： Bosch FX,de Sanjosé S

更新日期：2002-03-01 00:00:00

abstract：:The utility of lymphatic mapping and sentinel lymph node biopsy in malignancies of the female lower genital tract-- vulvar, vaginal, and cervical cancers--is being explored in multiple centers internationally. For patients with these tumors, lymphatic mapping with sentinel lymph node biopsy holds the promise of increa...

journal_title：Current oncology reports

authors： Frumovitz M,Ramirez PT,Levenback C

更新日期：2005-11-01 00:00:00

abstract：:Although postoperative chemoradiation has a proven role in the treatment of stage II to III localized rectal cancer, recent trials have demonstrated the role of preoperative chemoradiation. A recent randomized trial has shown that preoperative chemoradiation yields higher rates of local control and sphincter preservat...

journal_title：Current oncology reports

authors： Das P,Crane CH

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to sum up the state of the art of urachal carcinoma (UC) in order to easily guide clinicians. RECENT FINDINGS:UC is a rare and aggressive disease with consequent few data about diagnosis and treatment. Dates are mainly based on retrospective trial and case reports with limit...

journal_title：Current oncology reports

authors： Claps M,Stellato M,Zattarin E,Mennitto A,Sepe P,Guadalupi V,Mennitto R,de Braud FGM,Verzoni E,Procopio G

更新日期：2020-01-27 00:00:00

abstract：:Gamma-(γ)-herpes virus lymphomas comprise a heterogenous group of B-cell and T-cell neoplasms most commonly associated with Epstein-Barr virus and rarely human herpes virus-8 infection. Adult T-cell leukemia/lymphoma (ATLL) is a unique disease entity caused by the human T-cell lymphotrophic virus, type 1 (HTLV-I), the...

journal_title：Current oncology reports

authors： Ramos JC,Lossos IS

更新日期：2011-10-01 00:00:00

abstract：:Malignant pleural effusions (MPEs) are a significant source of cancer-related morbidity. Over 150,000 patients in the United States suffer from breathlessness and diminished quality of life due to MPE each year. Current management strategies are of mostly palliative value and focus on symptom control; they do not addr...

journal_title：Current oncology reports

authors： Bradshaw M,Mansfield A,Peikert T

更新日期：2013-06-01 00:00:00

abstract：:Cutaneous melanoma is a significant and increasing clinical problem. Knowing accurately the prognosis in a given patient is critical for treatment decisions and for optimal patient education. In this article we discuss the most current information regarding prognostic factors in early-stage and advanced malignant mela...

journal_title：Current oncology reports

authors： Buzaid AC,Anderson CM

更新日期：2000-07-01 00:00:00

abstract：:Successful immune targeting of malignancies hinges upon the ability to activate specific T-cell populations to recognize and attack tumor but spare normal vital tissues. Investigators in the field of tumor immunology are currently utilizing at least three distinct approaches toward this goal. In the first approach, mo...

journal_title：Current oncology reports

authors： Mackall CL,Helman LJ

更新日期：2000-11-01 00:00:00

abstract：:The number of patients given neoadjuvant chemotherapy (NAC) followed by fertility-sparing surgery in cervical cancer is still scarce. Only a few centres perform these procedures, and thus, such procedures remain largely in the experimental stage. Patients that do not fulfil the criteria for standard fertility-sparing ...

journal_title：Current oncology reports

authors： Robova H,Rob L,Halaska MJ,Pluta M,Skapa P

更新日期：2015-01-01 00:00:00

abstract：:The introduction of targeted therapies, specifically those that target the VEGF receptor (VEGFR), PDGF receptor (PDGFR) and the mTOR pathways, has significantly changed the approach to patients with unresectable renal cell cancer (RCC). However, drug resistance develops through bypassing of targeted pathways. Regorafe...

journal_title：Current oncology reports

authors： Zaki K,Aslam S,Eisen T

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite recent advances in the care of patients with advanced non-small cell lung cancer (NSCLC), significant morbidity and mortality remains. Symptoms caused by the cancer and its treatments can be profoundly debilitating. Palliative care aims to reduce this burden. In this review, we discuss the def...

journal_title：Current oncology reports

authors： Bhattacharya P,Dessain SK,Evans TL

更新日期：2018-11-09 00:00:00

abstract：:Electronic data sharing is a critical, but underappreciated, requirement for modern medical informatics systems. This capability is facilitated by acquisition of structured clinical data, but optimized only if this data is stored and transmitted using standardized representations. Most electronic medical record and cl...

journal_title：Current oncology reports

authors： Jones RB,Reeves D,Martinez CS

更新日期：2012-12-01 00:00:00

abstract：:Chordomas and chondrosarcomas of the skull base are rare, indolent tumors with a natural history of locally invading their surroundings. Safe, maximal resection is the mainstay of treatment, followed by adjuvant radiation therapy. Even with multimodality therapy, local recurrence remains the most common failure patter...

journal_title：Current oncology reports

authors： Nguyen QN,Chang EL

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:We aim to summarise the available evidence on systemic therapies for advanced anal cancer. RECENT FINDINGS:There is no universal consensus on the management of this condition and the prognosis remains poor. Nevertheless, significant progress has been recently made including completion of the first, e...

journal_title：Current oncology reports

authors： Sclafani F,Rao S

更新日期：2018-05-04 00:00:00

abstract：:Gastrointestinal stromal tumors (GISTs) are the most common soft tissue sarcoma, and most feature abnormalities in two genes encoding the receptor tyrosine kinases (RTKs), KIT, and PDGFRA. The RTK inhibitor imatinib revolutionized treatment in GIST; however, drug resistance remains a challenge. Constitutive autophosph...

journal_title：Current oncology reports

authors： Patel S

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Although surgery for lung cancer was not common before the early twentieth century, it has enjoyed remarkable progress since then both in type of resection and technical approach. This has been coupled with significant technological advances. Here, we will review the history and evolution of this rela...

journal_title：Current oncology reports

authors： Abbas AE

更新日期：2018-11-13 00:00:00

abstract：:Accurate, reproducible criteria for determining tumor response and progression after therapy are critical for optimal patient care and effective evaluation of novel therapeutic agents. Currently, the most widely used criteria for determining treatment response in gliomas is based on two-dimensional tumor measurements ...

journal_title：Current oncology reports

authors： Wen PY,Norden AD,Drappatz J,Quant E

更新日期：2010-01-01 00:00:00

abstract：:Concurrent radiation therapy and chemotherapy is the primary treatment for patients with squamous cell tumors of the anal canal, and is also employed in the neoadjuvant setting for patients with stage II and III adenocarcinoma of the rectum. There is constant clinical study involving modifications of chemoradiotherapy...

journal_title：Current oncology reports

authors： Meyer J,Balch G,Willett C,Czito B

更新日期：2011-06-01 00:00:00

abstract：:Most patients with chronic lymphocytic leukemia are diagnosed at an early stage, when traditional staging systems fail to distinguish those with an aggressive disease course from those with an excellent prognosis. This failure underscores the need for better prognostic markers. Although many markers have been explored...

journal_title：Current oncology reports

authors： Jain N,Lamanna N

更新日期：2009-09-01 00:00:00

abstract：:Inter-individual variability in carcinogen metabolism has been attributed in part to the polymorphic expression of several phase I and II detoxification enzymes. The role of these genetic polymorphisms in cancer susceptibility has been most extensively evaluated for isozymes of cytochrome P450 (CYP1A1, CYP2D6, and CYP...

journal_title：Current oncology reports

authors： Clapper ML

更新日期：2000-05-01 00:00:00

abstract：:Colon cancer remains the third most common cancer, and cause of cancer-related death in the United States. Greater public awareness and acceptance of screening programs have contributed significantly to increasingly earlier detection of colon cancer and decreased mortality. Advances made in the understanding of this d...

journal_title：Current oncology reports

authors： Kumar SK,Goldberg RM

更新日期：2001-03-01 00:00:00

abstract：:Acute promyelocytic leukemia (APL) is a disease associated with fusion oncoproteins invariably involving the retinoic acid receptor (Raralpha). Retinoic acid induces differentiation in APL cells and is successfully used in conjunction with chemotherapy to treat and cure a significant percentage of patients with APL. A...

journal_title：Current oncology reports

authors： Mann KK,Shao W,Miller WH Jr

更新日期：2001-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This review was undertaken to analyze the main reasons behind the limited development of hospice care in China, and to put forward some suggestions. RECENT FINDINGS:Although the Chinese government has increased its support for hospice care in recent years, however, owing to the lack of education arou...

journal_title：Current oncology reports

authors： Ling M,Wang X,Ma Y,Long Y

更新日期：2020-07-28 00:00:00