Radiologic sinus inflammation and symptoms of chronic rhinosinusitis in a population-based sample.

abstract：:In this study, we investigated the role of calcium and phospholipid-dependent protein kinase (protein kinase C, PKC) in the modulation of histamine release from human basophils. A novel and potent inhibitor of PKC, K-252a, inhibited the release of histamine induced by anti-IgE in a dose-dependent manner with ID50 (the...

journal_title：Allergy

authors： Morita Y,Takaishi T,Honda Z,Miyamoto T

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Children with spina bifida (SB) are exposed to latex soon after birth during bladder catheterization, rectal disimpaction, and multiple surgical procedures. IgE-mediated latex-allergic reactions have been reported recently in these children. Our study was designed to assess the prevalence of allergic reactio...

journal_title：Allergy

authors： Kattan H,Harfi H,Tipirneni P

更新日期：1999-01-01 00:00:00

abstract：:The protective effect of terfenadine on inflammatory processes following the early phase of conjunctival provocation tests by specific allergen was assessed in 24 patients suffering from seasonal allergic rhinoconjunctivitis, in a single-blind, randomized, placebo-controlled, parallel-group study. Patients were random...

journal_title：Allergy

authors： Ciprandi G,Buscaglia S,Iudice A,Canonica GW

更新日期：1992-08-01 00:00:00

abstract：:In studies on atopic dermatitis (AD), different scoring systems are used to evaluate the severity of the disease. The objective of this study was to investigate agreement between observers in the assessment of the overall severity of AD, and interobserver variation in the assessment of severity of AD for each scoring ...

journal_title：Allergy

authors： Sprikkelman AB,Tupker RA,Burgerhof H,Schouten JP,Brand PL,Heymans HS,van Aalderen WM

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Genetic modification of allergenic foods such as apple has the potential to reduce their clinical allergenicity, but this has never been studied by oral challenges in allergic individuals. METHODS:We performed oral food challenges in 21 apple-allergic individuals with Elstar apples which had undergone gene ...

journal_title：Allergy

authors： Dubois AE,Pagliarani G,Brouwer RM,Kollen BJ,Dragsted LO,Eriksen FD,Callesen O,Gilissen LJ,Krens FA,Visser RG,Smulders MJ,Vlieg-Boerstra BJ,Flokstra-de Blok BJ,van de Weg WE

更新日期：2015-11-01 00:00:00

abstract：:Sleep is fundamental for physical and mental health as well as daytime performance and represents a crucial aspect in the personal representations of well-being. Sleep disturbances in patients with chronic disorders constitute a factor that contributes to exacerbate symptoms, complicate management, and affect mood and...

journal_title：Allergy

authors： Baiardini I,Braido F,Cauglia S,Canonica GW

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Little information is available on the clinical efficacy of sublingual immunotherapy (SLIT) using extracts derived from mammalian epithelia. OBJECTIVES:To assess clinical efficacy of cat SLIT based on natural exposure challenge test (NCT). MATERIAL AND METHODS:Fifty cat allergic patients with rhinoconjunct...

journal_title：Allergy

authors： Alvarez-Cuesta E,Berges-Gimeno P,González-Mancebo E,Fernández-Caldas E,Cuesta-Herranz J,Casanovas M

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Nasopharynx-associated lymphoid tissue (NALT) serves as an important inductive site for mucosal immunity in the upper respiratory tract. Despite its importance in the mucosal immune system, little is known regarding the role of NALT in airway allergic immune responses. We aimed to elucidate the role of NALT ...

journal_title：Allergy

authors： Kim DY,Fukuyama S,Nagatake T,Takamura K,Kong IG,Yokota Y,Lee CH,Kiyono H

更新日期：2012-04-01 00:00:00

abstract：:Environmental exposures in pregnancy and the early postnatal period affect early immune development. Early immune function and future allergy susceptibility appear to result from a combination of maternal phenotype, infant genotype, and environmental exposures in utero that affect early gene expression. Furthermore, e...

journal_title：Allergy

authors： Prescott SL

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:While total IgE measurements are often used in clinical practice, it is unclear how they should be interpreted for the diagnosis of allergic disorders. We studied whether total IgE may be used to rule out or predict sensitization and whether there are age or gender differences. METHODS:ROC curves were asses...

journal_title：Allergy

authors： Kerkhof M,Dubois AE,Postma DS,Schouten JP,de Monchy JG

更新日期：2003-09-01 00:00:00

abstract：:Histamine is a key mediator in the development of allergy symptoms, and oral H(1)-antihistamines are among the most widely used treatments for symptomatic relief in conditions such as allergic rhinitis and chronic urticaria. Ebastine is a second-generation antihistamine which has been shown to be an effective treatmen...

journal_title：Allergy

authors： Sastre J

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Anaphylaxis is an acute, potentially fatal, multi-organ system, allergic reaction caused by the release of chemical mediators from mast cells and basophils. Uncertainty exists around epidemiological measures of incidence and prevalence, risk factors, risk of recurrence, and death due to anaphylaxis. This sys...

journal_title：Allergy

authors： Panesar SS,Javad S,de Silva D,Nwaru BI,Hickstein L,Muraro A,Roberts G,Worm M,Bilò MB,Cardona V,Dubois AE,Dunn Galvin A,Eigenmann P,Fernandez-Rivas M,Halken S,Lack G,Niggemann B,Santos AF,Vlieg-Boerstra BJ,Zolkipli Z

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The prevalence of allergic rhinoconjunctivitis has increased significantly over the past decades with grass pollen being a common trigger. The impact of allergy on patient's quality of life is substantial. AIM:To investigate the sustained effect on quality of life during the grass pollen season 1 year after...

journal_title：Allergy

authors： Frølund L,Durham SR,Calderon M,Emminger W,Andersen JS,Rask P,Dahl R

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Intranasal noninhaled delivery of carbon dioxide (CO₂) is efficacious in the symptomatic treatment of seasonal allergic rhinitis. The goal of this study was to determine whether and how 100% CO₂ inhibits mast cell degranulation, thereby possibly contributing to the reduction of symptoms in seasonal allergic ...

journal_title：Allergy

authors： Strider JW,Masterson CG,Durham PL

更新日期：2011-03-01 00:00:00

abstract：:The prevalence and specificity of naturally occurring human IgA anti-IgE autoantibodies (a-E Ab) were studied by ELISA with anti-IgA monoclonal antibodies (mAb) and a purified myeloma IgE as solid-phase protein, i.e., IgE-DES(kappa). Such detected IgA a-E Ab were common among adults, and significantly increased geomet...

journal_title：Allergy

authors： Magnusson CG

更新日期：1994-12-01 00:00:00

abstract：:We developed an antigen- and isotype-specific ELISA for the rapid detection of native serum immune complexes (IC). It is a sandwich assay, in which a solid phase antigen-specific capture antibody selectively binds the antigen-specific IC via the antigen. The isotype of the bound IC is then identified using an enzyme-l...

journal_title：Allergy

authors： Bell SJ,Potter PC

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Specific oral tolerance induction (SOTI) seems to be a promising treatment of food allergy. Specific oral tolerance induction and elimination diet were compared with respect to efficacy rate and patterns of clinical reaction. METHODS:Children with challenge proven immunoglobulin E (IgE)-mediated cow's milk ...

journal_title：Allergy

authors： Staden U,Rolinck-Werninghaus C,Brewe F,Wahn U,Niggemann B,Beyer K

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Signal transducer and activator of transcription 1 (STAT1), an intracellular signal transducer and activator of transcription centrally involved in many inflammatory pathways, was recently suggested to play an important role in allergy related immune responses. AIM:Thus, we investigated the effect of polymo...

journal_title：Allergy

authors： Pinto LA,Steudemann L,Depner M,Klopp N,Illig T,Weiland SK,von Mutius E,Kabesch M

更新日期：2007-12-01 00:00:00

abstract：:We investigated the prevalence of sensitization to the cat lipocalin Fel d 7 among 140 cat-sensitized Swedish patients and elucidated its allergenic activity and cross-reactivity with the dog lipocalin Can f 1. Sixty-five of 140 patients had IgE to rFel d 7 whereof 60 also had IgE to rCan f 1. A moderate correlation b...

journal_title：Allergy

authors： Apostolovic D,Sánchez-Vidaurre S,Waden K,Curin M,Grundström J,Gafvelin G,Cirkovic Velickovic T,Grönlund H,Thomas WR,Valenta R,Hamsten C,van Hage M

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Air-pollution levels have been shown to be associated with increased morbidity of respiratory diseases. METHODS:Data for ambient air-pollutant levels, meteorologic factors, and hospitalization or emergency room (ER) visits for acute asthma in Singapore children over a 5-year period (1990-4) were obtained an...

journal_title：Allergy

authors： Chew FT,Goh DY,Ooi BC,Saharom R,Hui JK,Lee BW

更新日期：1999-04-01 00:00:00

abstract：:Chronic rhinosinusitis (CRS) is a multifactorial disease of the upper airways with a high prevalence (approximately 11%) in the general population. Different immune and inflammatory mechanisms are involved in its pathogenesis. Alterations in the arachidonic acid pathway (leading to an imbalanced production of eicosano...

journal_title：Allergy

authors： Pezato R,Świerczyńska-Krępa M,Niżankowska-Mogilnicka E,Derycke L,Bachert C,Pérez-Novo CA

更新日期：2012-11-01 00:00:00

abstract：:This study was conducted to evaluate how bronchial responsiveness to direct and indirect stimuli relate to nitric oxide producing airway inflammation, and whether the relationship differs between atopic and nonatopic patients with various degrees of bronchial hyperresponsiveness and airway inflammation in a group of o...

journal_title：Allergy

authors： Rouhos A,Ekroos H,Karjalainen J,Sarna S,Sovijärvi AR

更新日期：2005-12-01 00:00:00

abstract：:Using monoclonal anti-human IgE antibodies recognizing the D epsilon 1 or D epsilon 2 epitope, we have developed a sandwich radioimmunoassay (RIA) to determine IgE in human cell cultures. With the help of this assay, various methods of measuring an actual de novo IgE synthesis were compared. It was necessary to subtra...

journal_title：Allergy

authors： Knutti-Müller JM,Stadler BM,Magnusson CM,de Weck L

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Asthma is a complex disorder, which is known to be affected by interactions between genetic and environmental factors. The human Eotaxin 1 and CCR3 attract eosinophils and Th2-lymphocytes to migrate to the inflammatory foci that could represent a key mechanism in allergy and asthma. OBJECTIVE:We hypothesize...

journal_title：Allergy

authors： Wang TN,Chiang W,Tseng HI,Chu YT,Chen WY,Shih NH,Ko YC

更新日期：2007-10-01 00:00:00

abstract：:Arachidonic acid metabolism represents an important source of mediators with ambivalent actions. Among these, lipoxins (LXs) are the first agents identified and recognized as anti-inflammatory endogenous lipid mediators, which are involved in the resolution of inflammation and are present in the airways of asthmatic p...

journal_title：Allergy

authors： Bonnans C,Chanez P,Chavis C

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:A cross-sectional retrospective study suggested a link between allergic diseases and Parkinson's disease. However, the temporal association between asthma and Parkinson's disease remains unknown. METHODS:From the Taiwan National Health Insurance Research Database, 10 455 patients who were diagnosed with ast...

journal_title：Allergy

authors： Cheng CM,Wu YH,Tsai SJ,Bai YM,Hsu JW,Huang KL,Su TP,Li CT,Tsai CF,Yang AC,Lin WC,Pan TL,Chang WH,Chen TJ,Chen MH

更新日期：2015-12-01 00:00:00

abstract：:The usefulness of the leukocyte migration inhibition factor (LIF) test to detect cow milk (CM) hypersensitivity was studied in 40 children with suspected allergy to CM. Hypersensitivity was carefully investigated by oral milk challenges, which gave a final confirmation of cow milk hypersensitivity in 12 subjects, and ...

journal_title：Allergy

authors： Vanto T,Smogorzewska EM,Viander M,Kalimo K,Koivikko A

更新日期：1987-11-01 00:00:00

abstract：:To determine optimal conditions for allergen preservation, we investigated the influence of different stabilizing additives and of storage temperature on the allergen activity of apple protein preparations, obtained by extraction in phosphate buffer or by precipitation in diacetone alcohol and resolubilization in phos...

journal_title：Allergy

authors： Rudeschko O,Fahlbusch B,Henzgen M,Schlenvoigt G,Herrmann D,Vieths S,Jäger L

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Whereas recent studies underlie the fundamental importance of the CC chemokine receptor 3 (CCR3) for the recruitment of eosinophils in allergic diseases, controversial data exist about the relevance of CCR1 on eosinophils. Therefore, the purpose of this study was to investigate the expression and regulation ...

journal_title：Allergy

authors： Elsner J,Dulkys Y,Gupta S,Escher SE,Forssmann WG,Kapp A,Forssmann U

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Up to 10% of the patients in whom suspected betalactam hypersensitivity (HS) has been excluded by skin and challenge tests report suspected allergic reactions during subsequent treatments with the same or very similar betalactams. It has been suggested that the reactions may result from a resensitization ind...

journal_title：Allergy

authors： Ponvert C,Weilenmann C,Wassenberg J,Walecki P,Bourgeois ML,de Blic J,Scheinmann P

更新日期：2007-01-01 00:00:00