Abstract：
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Taheri S,Abdullah TL,Rafii MY,Harikrishna JA,Werbrouck SPO,Teo CH,Sahebi M,Azizi Pdoi
10.1038/s41598-019-53129-xsubject
Has Abstractpub_date
2019-11-05 00:00:00pages
16395issue
1issn
2045-2322pii
10.1038/s41598-019-53129-xjournal_volume
9pub_type
已发布勘误abstract：:Gram-positive bacteria homeostasis and antibiotic resistance mechanisms are dependent on the intricate architecture of the cell wall, where amidated peptidoglycan plays an important role. The amidation reaction is carried out by the bi-enzymatic complex MurT-GatD, for which biochemical and structural information is ve...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22986-3
更新日期：2018-03-28 00:00:00
abstract：:High-altitude retinopathy is initiated by hypobaric hypoxia and characterized by retinal functional changes, but the precise cellular and molecular mechanisms that mediate this dysfunction remain unclear. The aim of our investigation is to determine the protective efficacy of hesperidin (HSD) on the hypobaric hypoxia-...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76156-5
更新日期：2020-11-10 00:00:00
abstract：:Oestrogen is an important regulator in reproduction. To understand the role of oestrogen receptor 1 (ESR1) in Leydig cells, we investigated the expression of ESR1 in mouse Leydig cells during postnatal development and the effects of oestrogen on steroidogenesis and proliferation of progenitor Leydig cells (PLCs). In L...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep43459
更新日期：2017-03-07 00:00:00
abstract：:We report a multi-channel optical frequency synthesizer developed to generate extremely stable continuous-wave lasers directly out of the optical comb of an Er-doped fiber oscillator. Being stabilized to a high-finesse cavity with a fractional frequency stability of 3.8 × 10-15 at 0.1 s, the comb-rooted synthesizer pr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44122-5
更新日期：2019-05-21 00:00:00
abstract：:Brain-computer interfaces enable active communication and execution of a pre-defined set of commands, such as typing a letter or moving a cursor. However, they have thus far not been able to infer more complex intentions or adapt more complex output based on brain signals. Here, we present neuroadaptive generative mod...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71287-1
更新日期：2020-09-07 00:00:00
abstract：:Parkinson's disease (PD) is a degenerative disorder that affects the central nervous system. PD-related alterations in structural and functional neuroimaging have not been fully explored. This study explored multi-modal PD neuroimaging and its application for predicting clinical scores on the Movement Disorder Society...
journal_title：Scientific reports
pub_type： 杂志文章,随机对照试验
doi：10.1038/srep38070
更新日期：2016-11-30 00:00:00
abstract：:The present study aimed to evaluate the accuracy and repeatability of morphological contour interpolation (MCI)-based semiautomatic segmentation method for volumetric measurements of bone grafts around dental implants. Three in vitro (one with a cylinder and two with a geometrically complex form) and four ex vivo mode...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71651-1
更新日期：2020-09-10 00:00:00
abstract：:The aim of the present work was to study whether the leptin-adiponectin axis may have a pathophysiological role in the increased systemic inflammation and oxidative stress observed in patients with the metabolic syndrome (MS). Leptin, adiponectin, and markers of inflammation and oxidative stress were measured in a sam...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-06997-0
更新日期：2017-07-26 00:00:00
abstract：:The extracellular matrix (ECM) impacts stem cell differentiation, but identifying formulations supportive of differentiation is challenging in 3D models. Prior efforts involving combinatorial ECM arrays seemed intuitively advantageous. We propose an alternative that suggests reducing sample size and technological burd...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep18705
更新日期：2015-12-21 00:00:00
abstract：:Enterovirus 71 (EV71) is a major pathogen of hand, foot, and mouth disease (HFMD). To date, no antiviral drug has been approved to treat EV71 infection. Due to the essential role that EV71 3 C protease (3Cpro) plays in the viral life cycle, it is generally considered as a highly appealing target for antiviral drug dev...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10840-x
更新日期：2017-09-04 00:00:00
abstract：:Electronic cigarettes (ECs) are nicotine delivery devices that are proposed as tobacco harm reduction products to smokers. Nicotine delivery from ECs is potentially important in their efficacy as smoking substitutes. Herein, nicotine delivery from using a new-generation EC device (variable-wattage, set at 9 W) was eva...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11269
更新日期：2015-06-17 00:00:00
abstract：:The modern Asian monsoonal systems are currently believed to have originated around the end of the Oligocene following a crucial step of uplift of the Tibetan-Himalayan highlands. Although monsoon possibly drove the evolution of many mammal lineages during the Neogene, no evidence thereof has been provided so far. We ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09008
更新日期：2015-03-11 00:00:00
abstract：:Identification of AD (Alzheimer's disease)-related genes obtained from blood samples is crucial for early AD diagnosis. We used three public datasets, ADNI, AddNeuroMed1 (ANM1), and ANM2, for this study. Five feature selection methods and five classifiers were used to curate AD-related genes and discriminate AD patien...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60595-1
更新日期：2020-02-26 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-57850-w
更新日期：2020-01-21 00:00:00
abstract：:Two-photon polymerization (TPP) is capable of fabricating 3D structures with dimensions from sub-µm to a few hundred µm. As a direct laser writing (DLW) process, fabrication time of 3D TPP structures scale with the third order, limiting its use in large volume fabrication. Here, we report on a scalable fabrication met...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-64955-9
更新日期：2020-05-26 00:00:00
abstract：:Normalization procedures for the qRT-PCR analysis of miRNA in biological samples are recommended to reduce the variability caused by pre-analytical factors. Since there is no universal standardized normalization strategy for miRNA qRT-PCR studies, we conducted a throughout study to evaluate a panel of small non-coding...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-59682-0
更新日期：2020-02-21 00:00:00
abstract：:In recent decades Madagascar has experienced significant habitat loss and modification, with minimal understanding of how human land use practices have impacted the evolution of its flora and fauna. In light of ongoing and intensifying anthropogenic pressures, we seek new insight into mechanisms driving genetic variab...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52689-2
更新日期：2019-11-07 00:00:00
abstract：:Microbial life below the seafloor has changed over geological time, but these changes are often not obvious, as they are not recorded in the sediment. Sulphur (S) isotope values in pyrite extracted from a Plio- to Holocene sequence of the Peru Margin (Ocean Drilling Program, ODP, Site 1229) show a down-core pattern th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-36943-7
更新日期：2019-01-24 00:00:00
abstract：:Unlike MoS2 ultra-thin films, where solution-based single source precursor synthesis for electronic applications has been widely studied, growing uniform and large area few-layer WS2 films using this approach has been more challenging. Here, we report a method for growth of few-layer WS2 that results in continuous and...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-58694-0
更新日期：2020-02-03 00:00:00
abstract：:The newly discovered Candidatus 'Methanoperedens nitroreducens' (M. nitroreducens), mediating nitrate-dependent anaerobic oxidation of methane, is an important microorganism in linking carbon and nitrogen cycles. In order to explore the diversity of M. nitroreducens-like archaea in various environmental niches with ad...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24974-z
更新日期：2018-05-16 00:00:00
abstract：:Efficient mitochondrial Ca2+ uptake takes place at contact points between the ER and mitochondria, and represents a key regulator of many cell functions. In a previous study with HeLa cells, we showed that ER-to-mitochondria Ca2+ transfer increases during the early phase of ER stress induced by tunicamycin as an adapt...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36394
更新日期：2016-11-03 00:00:00
abstract：:Predicting regions at risk from introductions of non-native species and the subsequent invasions is a fundamental aspect of horizon scanning activities that enable the development of more effective preventative actions and planning of management measures. The Asian cyprinid fish topmouth gudgeon Pseudorasbora parva ha...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26316
更新日期：2016-05-20 00:00:00
abstract：:Most studies on buoyant microplastics in the marine environment rely on sea surface sampling. Consequently, microplastic amounts can be underestimated, as turbulence leads to vertical mixing. Models that correct for vertical mixing are based on limited data. In this study we report measurements of the depth profile of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33882
更新日期：2016-10-10 00:00:00
abstract：:The 3D MHD nonlinear radiative hybrid nanofluid flow across an irregular dimension sheet with slip effect is studied numerically. The hybrid nanofluid consists of copper oxide (CuO) and magnesium oxide (MgO) nanoparticles embedded in methanol or methyl alcohol (MA). The governing PDEs' are altered as ODEs' using simil...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66102-w
更新日期：2020-06-08 00:00:00
abstract：:Rheumatoid Arthritis (RA) causes chronic inflammation of joints. The cytokines TNFα and IFNγ are central players in RA, however their source has not been fully elucidated. Natural Killer (NK) cells are best known for their role in elimination of viral-infected and transformed cells, and they secrete pro-inflammatory c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37448-z
更新日期：2019-02-04 00:00:00
abstract：:The anuran amphibian Xenopus laevis can regenerate its limbs for a limited time during the larval stage, while limbs are still developing. Using this regeneration model, we evaluated the proximo-distal blastema cell identity when endogenous retinoids were increased by CYP26 inhibition or when RAR-specific agonists alt...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01886
更新日期：2013-01-01 00:00:00
abstract：:Milk microbiota has a great influence on the safety and quality of dairy products. However, few studies have investigated the variations of bacterial composition in raw milk. In this study, raw milk samples were collected in 12 successive months, and their bacterial compositions were determined by 16 S rRNA gene seque...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-20862-8
更新日期：2018-02-05 00:00:00
abstract：:In spite of intensive investigations, the role of spontaneous breathing (SB) activity in ARDS has not been well defined yet and little has been known about the different contribution of inspiratory or expiratory muscles activities during mechanical ventilation in patients with ARDS. In present study, oleic acid-induce...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep42785
更新日期：2017-02-23 00:00:00
abstract：:Imaging the distribution of sphingomyelin (SM) in membranes is an important issue in lipid-raft research. Recently we developed novel fluorescent SM analogs that exhibit partition and dynamic behaviors similar to native SM, and succeeded in visualizing lateral domain-segregation between SM-rich liquid-ordered (Lo) and...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16361-x
更新日期：2017-12-01 00:00:00
abstract：:We developed a new concept of X- and γ-ray radiation semiconductor detectors based on a large area graphene/semi-insulating single crystal CdTe Schottky-type heterojunction. These two terminal electronic devices can be easily fabricated by forming a Van der Waals contact between large area chemical vapor deposited gra...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37637-w
更新日期：2019-01-31 00:00:00
